Lada
Lada Bemert, Solingen DE
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20120180741 | METHOD FOR THE IN SITU PRODUCTION OF FUEL/WATER MIXTURES IN COMBUSTION ENGINES - A process for operating an internal combustion engine or a nozzle includes producing a fuel mixture in-situ. The fuel mixture consists of a polar component A, a nonpolar fuel component B, an amphiphilic component C, and an auxiliary component D. The fuel mixture is produced in a high-pressure region of an injection system of an internal combustion engine or of a nozzle within 10 seconds of an injection operation. The fuel mixture is injected into the internal combustion engine or the nozzle. A pressure is in a range of from 100 to 4,000 bar. | 07-19-2012 |
Lada Martincova, Kostelec Nad Orlici CZ
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20140284827 | METHOD FOR PRODUCTION OF MATERIALS HAVING ANISOTROPIC PROPERTIES COMPOSED OF NANOFIBRES OR MICROFIBRES AND AN APPARATUS FOR IMPLEMENTATION OF SAID METHOD - A method of producing fibres includes continuously drawing a fibre out of a solution, and pulling it to a rotary set of n electrodes by means of an electrostatic field. The individual electrodes of the set are arranged at regular spacing to each other and at the same distance from the set's rotation axis, and parallel with it. The fibre is wound on the set of electrodes by rotating the set of electrodes. The electrostatic field is disconnected and rotation of the set of electrodes is stopped. A layer of the fibres formed in the field between two adjacent electrodes is removed. The rotating set of electrodes turns through an angle of 360/n, the layer of the fibres formed between two adjacent electrodes in the field adjacent to the field from which the layer was removed, is removed, and this step is repeated in total n-times. | 09-25-2014 |
Lada Mitchell, Allschwil CH
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20130095172 | USES FOR AND ARTICLE OF MANUFACTURE INCLUDING HER2 DIMERIZATION INHIBITOR PERTUZUMAB - The present application describes uses for and articles of manufacture including Pertuzumab, a first-in-class HER2 dimerization inhibitor. In particular, the application describes methods for extending progression free survival in a HER2-positive breast cancer patient population; combining two HER2 antibodies to treat HER2-positive cancer without increasing cardiac toxicity; treating early-stage HER2-positive breast cancer; treating HER2-positive cancer by co-administering a mixture of Pertuzumab and Trastuzumab from the same intravenous bag; treating HER2-positive metastatic gastric cancer; treating HER2-positive breast cancer with Pertuzumab, Trastuzumab and Vinorelbine; treating HER2-positive breast cancer with Pertuzumab, Trastuzumab and aromatase inhibitor; and treating low HER3 ovarian, primary peritoneal, or fallopian tube cancer. It also describes an article of manufacture comprising a vial with Pertuzumab therein and a package insert providing safety and/or efficacy data thereon; a method of making the article of manufacture; and a method of ensuring safe and effective use of Pertuzumab related thereto. In addition the application describes an intravenous (IV) bag containing a stable mixture of Pertuzumab and Trastuzumab suitable for administration to a cancer patient. | 04-18-2013 |
20130195851 | ARTICLES OF MANUFACTURE AND METHODS FOR CO-ADMINISTRATION OF ANTIBODIES - The present invention relates to articles of manufacture and methods for co-administration of antibodies and/or antibody-like molecules, and further concerns methods for intravenous administration of more than one antibody and/or antibody-like molecule to a subject in need from a stable mixture contained in the same article of manufacture, such as an intravenous infusion bag (IV bag). | 08-01-2013 |
Lada Rasochova, Del Mar, CA US
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20090093019 | PRODUCTION AND IN VIVO ASSEMBLY OF SOLUBLE RECOMBINANT ICOSAHEDRAL VIRUS-LIKE PARTICLES - The present invention provides an improved method for the in vivo production of soluble assembled virus-like particles (“VLPs”) in bacterial cells of Pseudomonad origin. The Pseudomonad cells support assembly of VLPs from icosahedral viral capsid proteins (“CPs”) in vivo, and allow the inclusion of larger recombinant peptides as monomers or concatamers in the VLP. The invention specifically provides an improved method for the in vivo production of soluble assembled Cowpea Chlorotic Mottle Virus (“CCMV”) VLPs by introducing modifications into the CCMV CP that result in high yield production of soluble CP fusions in a | 04-09-2009 |
20090117144 | Recombinant flu vaccines - The present invention provides compositions for use as vaccines against the influenza virus, and rapid methods of producing such compositions. The composition include i) at least one peptide derived from an influenza virus, wherein the peptide is fused to a capsid protein derived from a plant virus forming a recombinant capsid fusion peptide and ii) at least one isolated antigenic protein or protein fragment derived from a human or avian influenza virus. The isolated antigenic protein or protein fragment derived from the human or avian influenza virus can be conjugated to the surface of the recombinant capsid fusion peptide. | 05-07-2009 |
20090158473 | SEED-PREFERRED GENE PROMOTERS FROM THE CASTOR PLANT - A nucleotide sequence comprising a nucleotide sequence having at least about 90% homology to the sequence of SEQ ID NO:9 or SEQ ID NO:10. Nucleotide sequences interest operatively linked to nucleotide sequence having at least about 90% homology to the sequence of SEQ ID NO:9 or SEQ ID NO:10 are disclosed. Vectors, methods of regulating target expression, methods of providing a cells, plants, and seeds comprising the nucleotide sequence are also disclosed. | 06-18-2009 |
Lada Rasochova, Madison, WI US
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20090106855 | Expression cassette for transformation comprising a modified viral sequence driven by a suitable promoter - Disclosed herein are novel methods and materials directed to transforming a host cell and expressing exogenous RNA therein. Specifically disclosed are DNA-launching platforms used to introduce a replicating viral segment attached to an exogenous polynucleotide into a cell, whereby the exogenous polynucleotide is expressed in said cell and confers a detectable trait. | 04-23-2009 |
Lada Suková, Dobruska CZ
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20140030370 | COMBINED SPINNING NOZZLE FOR THE MANUFACTURE OF NANOFIBROUS AND MICROFIBROUS MATERIALS - The combined spinning nozzle for the production of nanofibrous or microfibrous materials according to the invention comprises a thin-walled electrode and a first non-conductive body adjoining the first wall of said thin-walled electrode, said first body having its wall, which faces the thin-walled electrode, provided with an array of grooves formed therein, said grooves leading to the distal end of the combined spinning nozzle and having their proximal ends connected to a supply of spinning mixture. The thin-walled electrode as well as the first non-conductive body may assume either plate-like or cylindrical shapes. The combined spinning nozzle may further comprise the second non-conductive body adjoining the second wall of the thin-walled electrode and directing the air from the proximal end towards the distal end of the nozzle. The combined spinning nozzle is easy to dismantle and clean since the spinning capillaries assume the shape of the grooves formed on the surfaces of the first or third non-conductive bodies. | 01-30-2014 |