Patent application number | Description | Published |
20080214534 | (1,10B-Dihydro-2-(Aminoalkyl-Phenyl)-5H-Pyrazolo[1,5-C][1,3]Benzoxazin-5-Yl)Phenyl Methanone Derivatives as Hiv Viral Replication Inhibitors - The present invention relates to 5H-pyrazolo[1,5-c][1,3]benzoxazin-5-yl)phenyl methanone derivatives as inhibitors of the viral replication of the HIV virus, processes for their preparation as well as pharmaceutical compositions, their use as medicines, and diagnostic kits comprising them. The present invention also concerns combinations of the present HIV inhibitors with other anti-retroviral agents. It further relates to their use in assays as reference compounds or as reagents. The compounds of the present invention are useful for preventing or treating infection by HIV and for treating AIDS. | 09-04-2008 |
20080234288 | Hcv Inhibiting Sulfonamides - The present invention concerns sulfonamide derivatives having the general formula | 09-25-2008 |
20080262058 | Macrocylic Inhibitors of Hepatitis C Virus - Inhibitors of HCV replication of formula (I) | 10-23-2008 |
20080269322 | Substituted Aminophenylsulfonamide Compounds as Hiv Protease Inhibitor - The present invention concerns substituted aminophenylsulfonamide compounds, their use as protease inhibitors, in particular as broad-spectrum HIV protease inhibitors, processes for their preparation as well as pharmaceutical compositions and diagnostic kits comprising them. The present invention also concerns combinations of the present substituted aminophenylsulfonamide compounds with another anti-retroviral agent. It further relates to their use in assays as reference compounds or as reagents. | 10-30-2008 |
20080306061 | Aminophenylsulfonamide Derivatives as Hiv Protease Inhibitor - The present invention concerns substituted aminophenylsulfonamide compounds and derivatives, their use as protease inhibitors, in particular as broadspectrum HIV protease inhibitors, processes for their preparation as well as pharmaceutical compositions and diagnostic kits comprising them. The present invention also concerns combinations of the present substituted aminophenylsulfonamide compounds and derivatives with another anti-retroviral agent. It further relates to their use in assays as reference compounds or as reagents. | 12-11-2008 |
20090131460 | PYRIDO[2,3-D]PYRIMIDINES USEFUL AS HCV INHIBITORS, AND METHODS FOR THE PREPARATION THEREOF - The present invention relates to the use of pyrido[2,3-d]pyrimidines as inhibitors of HCV replication as well as their use in pharmaceutical compositions aimed to treat or combat HCV infections. In addition, the present invention relates to pyrido-[2,3-d]pyrimidines compounds per se and their use as medicines. The present invention also concerns processes for the preparation of such compounds, pharmaceutical compositions comprising them, and combinations of said compounds with other anti-HCV agents. | 05-21-2009 |
20090156595 | Pteridines useful as HCV inhibitors and methods for the preparation thereof - The present invention relates to the use of pteridines as inhibitors of HCV replication as well as their use in pharmaceutical compositions aimed to treat or combat HCV infections. In addition, the present invention relates to compounds per se and their use as medicines. The present invention also concerns processes for the preparation of such compounds, pharmaceutical compositions comprising them, and combinations of said compounds with other anti-HCV agents. | 06-18-2009 |
20090281140 | Macrocyclic inhibitors of hepatitis c virus - Inhibitors of HCV replication of formula (I) | 11-12-2009 |
20090281141 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS - Inhibitors of HCV replication of formula (I) | 11-12-2009 |
20100087649 | QUINOLINONE DERIVATIVES - HIV inhibitory compounds of formula (I) including the stereoisomeric forms thereof, the pharmaceutically acceptable salts, and pharmaceutically acceptable solvates thereof; wherein R | 04-08-2010 |
20100240698 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS - Inhibitors of HCV of formula al | 09-23-2010 |
20110160468 | PROCESS FOR THE PREPARATION OF (3R,3AS,6AR)-HEXAHYDROFURO [2,3-B] FURAN-3-YL (1S,2R)-3-[[(4-AMINOPHENYL) SULFONYL] (ISOBUTYL) AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE - The present invention relates to a process for the preparation of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate as well as novel intermediates for use in said process. (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate is particularly useful as an HIV protease inhibitor. | 06-30-2011 |
20120171157 | Macrocyclic Inhibitors Of Hepatitis C Virus - Inhibitors of HCV replication of formula (I) | 07-05-2012 |
20120202859 | Macrocyclic Inhibitors of Hepatitis C Virus - Inhibitors of HCV replication of formula (I) | 08-09-2012 |
20130089520 | Macrocyclic Inhibitors Of Hepatitis C Virus - Inhibitors of HCV replication of formula (I) | 04-11-2013 |
20130217725 | Macrocyclic Inhibitors Of Hepatitis C Virus - Inhibitors of HCV replication of formula (I) | 08-22-2013 |
20140255347 | Macrocyclic Inhibitors Of Hepatitis C Virus - Inhibitors of HCV replication of formula (I) | 09-11-2014 |