Kim, MD
Alison M. Kim, Bethesda, MD US
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20130017602 | MODULATION OF OOCYTE MEIOTIC PROGRESSION AND OOCYTE ACTIVATION - The present invention provides methods, compositions, and systems for reinitiating meiosis in cells in meiotic arrest and oocyte activation in fertilized, but un-activated, oocytes. In certain embodiments, Zn-binding moieties (e.g., zinc chelators) are used for reinitiating meiosis or oocyte activation. | 01-17-2013 |
Angelina Rochelle Kim, Silver Spring, MD US
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20110203035 | Cuff Protector - A clip that fastens the cuffs of apparel, such as pants, shirts, and skirts, without doing damage to the apparel fabric. This is accomplished primarily by means of a crimp located at the clip's base, configured to keep the clip's outer and inner edges close together but not in contact at the clip's base. The crimp, a feature lacking in previously patented pants cuff clips, is found in most of the embodiments of the present invention. Other features designed to hold apparel fabric in place are included in other embodiments, to include a rubber coating placed on the surface of the clip, a rubber stopper placed on the tip of the clip's inner edge, a hinge placed at the junction of the crimp and the inner edge, a pin and clasp to hold the apparel material, and magnets that clasp the apparel material. | 08-25-2011 |
Anthony Kim, Laurel, MD US
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20110181721 | OPTICAL PATH PROTECTION DEVICE AND METHOD FOR A RAILROAD TRACK INSPECTION SYSTEM - A railroad track inspection system and method for facilitating inspection of a rail component while traveling on the railroad track. The railroad track inspection system includes an optical path protection device for a protective window for optical sensors of an optical inspection system when it becomes contaminated with dirt, dust, mud, grease, and other contaminants that block or obscure an optical path of the sensors. The optical path protection device eliminates the need for a human operator to perform the periodic cleaning of the protective window by using a clear film with an automated advancement mechanism for providing clean film, as needed, for keeping the optical path of the optical sensors unobstructed and clear. | 07-28-2011 |
Chunwoo Kim, Baltimore, MD US
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20140039314 | Remote Center of Motion Robot for Medical Image Scanning and Image-Guided Targeting - The present invention pertains to a remote center of motion robot for medical image scanning and image-guided targeting, hereinafter referred to as the “Euler” robot. The Euler robot allows for ultrasound scanning for 3-Dimensional (3-D) image reconstruction and enables a variety of robot-assisted image-guided procedures, such as needle biopsy, percutaneous therapy delivery, image-guided navigation, and facilitates image-fusion with other imaging modalities. The Euler robot can also be used with other handheld medical imaging probes, such as gamma cameras for nuclear imaging, or for targeted delivery of therapy such as high-intensity focused ultrasound (HIFU). 3-D ultrasound probes may also be used with the Euler robot to provide automated image-based targeting for biopsy or therapy delivery. In addition, the Euler robot enables the application of special motion-based imaging modalities, such as ultrasound elastography. | 02-06-2014 |
20150065886 | COHESIVE ROBOT-ULTRASOUND PROBE FOR PROSTATE BIOPSY - An embodiment in accordance with the present invention provides a device and method for a transrectal ultrasound (TRUS) guided prostate biopsy. The device includes an ultrasound wand equipped with a lateral fire ultrasound sensor. The ultrasound wand also defines a channel having an oblique path though the wand. The channel accommodates a biopsy needle, which can be pivoted as well inserted through the channel to different depths in order to perform a biopsy of the prostate. The device therefore uses only three degrees-of-freedom of movement in order to obtain the biopsy samples. Additionally, the ultrasound wand can be used to generate a three-dimensional image of the prostate. | 03-05-2015 |
Deog J. Kim, Rockville, MD US
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20090270358 | PHARMACEUTICAL FORMULATION OF CLAVULANIC ACID - The present invention generally relates to stable pharmaceutical compositions, and methods of making and administering such compositions. In one aspect, the invention features stabilized pharmaceutical compositions that include pharmaceutically active ingredients such as potassium clavulanate or Clavitesse™, preferably in an immediate-release solid dosage form or an extended-release solid dosage form. Also provided are methods for making and using such immediate-release and stabilized compositions or extended-release and stabilized compositions. | 10-29-2009 |
20100099644 | HPMA - DOCETAXEL OR GEMCITABINE CONJUGATES AND USES THEREFORE - Disclosed are water-soluble compositions of gemcitabine and docetaxel formed by conjugating the gemcitabine or docetaxel to a water-soluble polymer such as N-2-hydroxypropyl methacrylamide (HPMA). Also disclosed are methods of using the compositions of the invention for the treatment of cancer. | 04-22-2010 |
20100255099 | CLAVULANATE FORMULATION FOR NEUROPROTECTION AND TREATMENT OF NEURODEGENERATIVE DISORDERS - The present invention generally relates to use of a stable solid pharmaceutical compositions that includes a clavulanate as the pharmaceutically active ingredients in an immediate-release or an extended-release solid dosage form. The composition can be used in a method of treating a neurodegenerative disease, providing neuroprotection, or preventing neuronal cell loss or death. Exemplary neurodegenerative diseases include Parkinson's disease, Alzheimer's disease and multiple sclerosis. | 10-07-2010 |
20110086111 | POLYMERIC SYSTEMS FOR THE DELIVERY OF ANTICANCER DRUGS - The present invention relates to compositions for the treatment of cancerous tissues in warm-blooded animals containing one or two anticancer agents attached to polymeric carriers having monomer units derived from one or more of N-(2-carboxypropyl)methacrylamide (2-CPMA), N-(3-carboxypropyl)methacrylamide (3-CPMA), N-(2-aminopropyl)methacrylamide (2-APMA) and/or N-(3-aminopropyl)methacrylamide (3-APMA) are also included. Anticancer agents in compositions can be attached to said polymeric carrier by side-chains which can be susceptible to hydrolysis by lysosomal enzymes intracellularly. Compositions can also include a targeting ligand attached to the polymeric carrier, optionally through a second linker. | 04-14-2011 |
20150071872 | POLYMERIC SYSTEMS FOR THE DELIVERY OF ANTICANCER DRUGS - The present invention relates to compositions for the treatment of cancerous tissues in warm-blooded animals containing one or two anticancer agents attached to polymeric carriers having monomer units derived from one or more of N-(2-carboxypropyl)methacrylamide (2-CPMA), N-(3-carboxypropyl)methacrylamide (3-CPMA), N-(2-aminopropyl)methacrylamide (2-APMA) and/or N-(3-aminopropyl)methacrylamide (3-APMA) are also included. Anticancer agents in compositions can be attached to said polymeric carrier by side-chains which can be susceptible to hydrolysis by lysosomal enzymes intracellularly. Compositions can also include a targeting ligand attached to the polymeric carrier, optionally through a second linker. | 03-12-2015 |
Deog Joong Kim, Rockville, MD US
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20130315937 | LIPID NANOPARTICLE COMPOSITIONS FOR ANTISENSE OLIGONUCLEOTIDES DELIVERY - Described is a lipid nanoparticle composition that includes a macromolecule conjugated to a polymer and a targeting agent. The composition can include a therapeutic agent. The therapeutic agent can be an antisense oligonucleotide (ASO). Exemplary ASOs are targeted to a portion of a nucleic acid encoding Akt-1, and which modulates the expression of Akt-1; or targeted to a portion of a nucleic acid encoding HIF-1, and which modulates the expression of HIF-1. Also described is a lipid nanoparticle composition that includes a macromolecule conjugated to a polymer and a therapeutic agent that is an ASO such as an ASO targeted to a portion of a nucleic acid encoding Akt-1, and which modulates the expression of Akt-1 or an ASO targeted to a portion of a nucleic acid encoding HIF-1, and which modulates the expression of HIF-1. Pharmaceutical formulations, methods of making the lipid nanoparticles, and methods of using the lipid nanoparticles, for example for treating cancers, are also disclosed. | 11-28-2013 |
20140275129 | TETRAHYDROISOQUINOLIN-2-YL-(QUINAZOLIN-4-YL)METHANONE COMPOUNDS - Tetrahydroisoquinolin-2-yl-(quinazolin-4-yl)methanone derivatives represented by formula (I), pharmacologically acceptable salts thereof, and compositions containing such compounds are described. Methods for treating hyperproliferative disorders by administering the compounds are also described. 1,2,3,4-tetrahydroisoquinoline derivatives for making tetrahydroisoquinolin-2-yl-(quinazolin-4-yl)methanone compounds are also described. | 09-18-2014 |
20140275537 | PROCESS FOR THE PREPARATION OF 4-AMINO-1-((1S,4R,5S)-2-FLUORO-4,5-DIHYDROXY-3-HYDROXYMETHYL-CYCLOPENT-2-- ENYL)-1H-PYRIMIDIN-2-ONE - Processes for the preparation of 4-amino-1-((1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-hydroxymethyl-cyclopent-2-enyl)-1H-pyrimidin-2-one (13, RX-3117) and its intermediates are described. | 09-18-2014 |
20150376142 | Process for the Preparation of 4-Amino-1-((1S,4R,5S)-2-Fluoro-4,5-Dihydroxy-3-Hydroxymethyl-Cyclopent-2-- Enyl)-1H-Pyrimidin-2-One - Processes for the preparation of 4-amino-1((1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-hydroxymethyl-cyclopent-2-enyl)-1H-pyrimidin-2-one (13, RX-3117) and its intermediates are described. | 12-31-2015 |
Dominic Kim, West Friendship, MD US
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20130324543 | REVERSAL OF HIGH BREAST CANCER RISK IN MAMMALS EXPOSED TO ESTROGENIC CHEMICALS IN UTERO BY ADULT EXPOSURE TO HDAC AND DNMT INHIBITORS - Methods of reducing breast cancer risk in an individual exposed in utero to an elevated estrogenic environment, where the individuals are identified by obtaining a measurement of at least one of: (a) DNMT1 expression; (b) methylation of normally unmethylated CpG islands of tumor suppressor genes; and (c) polycomb target genes, in cells obtained from the individual and comparing the measurement to a statistical level of a population not exposed in utero to an elevated estrogenic environment. Methods of reducing breast cancer risk in such an individual can be reduced by administering at least one DNA methyltransferase (DNMT) and/or histone deacetylase (HDAC) inhibitor. The administration of these inhibitors may be part of a treatment regime which may include the administration of at least one anti-cancer agent. | 12-05-2013 |
Douglas S. Kim, North Bethesda, MD US
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20090281163 | REGULATORY ELEMENTS THAT MEDIATE RETINAL CELL-SPECIFIC GENE EXPRESSION - Isolated nucleic acid molecules including regulatory elements that direct retinal-cell specific expression are provided. Methods for treating or preventing retinal disorders in a subject are also provided. | 11-12-2009 |
Edward Hyundeng Kim, Rockville, MD US
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20140349553 | Apparatus for and method of refurbishing a lacrosse ball - This invention relates to an apparatus and method for refurbishing lacrosse balls by using a fast, convenient, automated, entertaining, energy efficient, portable, and modular machine/method of removing a thin layer of rubber from the surface of a used lacrosse ball, by applying even pressure and random rotation of abrasive, one to four cups or rings, utilizing a combination of gravity and/or force of the cups against the surface of the ball, and the introduction of a solvent at various speeds, volume, and concentration, during and after the removal of a thin layer of rubber, to maximize the restoration of the rubber surface. | 11-27-2014 |
Eui-Soo Kim, Laurel, MD US
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20100184040 | COMPOSITIONS AND METHODS FOR DETERMINING LIKELIHOOD OF TWINNING - Collections of polynucleotides useful for estimating breeding value or detecting likelihood of twinning are disclosed. The polynucleotides are used to detect genomic sequences quantitatively associated with the twinning trait. Also disclosed are methods and kits for using the collections to estimate breeding value or predict likelihood of twinning. | 07-22-2010 |
Eunkyoung Kim, Woodstock, MD US
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20140332410 | ANALYTICAL MICRO-DEVICES FOR MENTAL HEALTH TREATMENT MONITORING - A lab on a chip device includes a whole blood inlet port and microchannels to transport a whole blood sample or plasma skimmed from the whole blood sample into a detection chamber that includes at least one 3-electrode set of a counter electrode, a working electrode and a reference electrode. The counter electrode, the working electrode and the reference electrode may present bare, unmodified surfaces that are disposed so that clozapine present in the whole blood sample is detected via a reduction-oxidation reaction. Alternatively, the working electrode surface may include catechol grafted to chitosan. A method of detecting analytes and biomarkers includes collecting a whole blood sample, loading the sample into a point-of-care testing (POCT) device that includes at least one working electrode; testing the sample for the occurrence of a redox reaction; and calculating the total oxidative charge when the working electrode is bare or modified as before. | 11-13-2014 |
Gabriel M. Kim, West Friendship, MD US
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20120259178 | AUTOMATED SURGICAL ILLUMINATION SYSTEM - The present invention provides illumination for a surgical procedure. Using an optical tracking system, the illumination is made to automatically track an optical marker on a surgical glove worn by a clinician to provide more consistent illumination for a surgical procedure. | 10-11-2012 |
Gabriel Min Kim, West Friendship, MD US
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20090275984 | REFORMING DEVICE - The present invention relates to a reforming device. A reforming device according to the present invention includes a main body that is locked to bones of a human body and of which a length is extensible depending on growth of the human body; an external controller that transmits a wireless control signal for a length of the main body to be extended inside of the human body; and an internal controller that is mounted inside of the human body and extends the length of the main body depending on the wireless control signal. | 11-05-2009 |
Grace J. Kim, Frederick, MD US
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20120178078 | Methods and Compositions for Nucleic Acid Detection - The present application relates to Multicomponent Nucleic Acid Enzymes (MNAzymes), which may be used for detecting, identifying and/or quantifying targets. More particularly, this application provides methods of designing and making more reliable MNAzymes, as well as compositions comprising MNAzyme components and methods of using MNAzymes. | 07-12-2012 |
Hee-Yong Kim, Potomac, MD US
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20150031878 | DERIVATIVES OF DOCOSAHEXAENOYLETHANOLAMIDE AND USES THEREOF - The invention provides derivatives of DEA which have increased potency and hydrolysis resistance as compared to DEA, and compositions thereof, as well as methods of using these derivatives to promote neurogenesis, neurite growth and/or length, and/or promote synaptogenesis. | 01-29-2015 |
Hosan Kim, Clarksville, MD US
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20160122697 | Devices and Methods for Creating and Testing Microbes and Biofilms - Systems and methods for growing microbes and biofilms on a hydrogel in a controlled environment. The system can have a cup, and a liner with the liner inserted into the cup and a hydrogel inserted into the liner. The cup, liner, and hydrogel assembly can be placed into a containment tray. The hydrogel can be sterilized before being placed into the containment tray. A lid can seal the cup, liner, and hydrogel into the containment tray. A lid can have inoculations ports, or can be made out of a self-sealable material keeping the inside environment sterilized and free of contaminants. The hydrogel can be inoculated with microbes through the inoculations ports, and incubated for a period of time at a set temperature to allow the microbes, and biofilms time to grow. After being grown the microbes and biofilms can be separated from each other allowing for both microbes and biofilm to be separately tested. | 05-05-2016 |
Hyuncheol Kim, Greenbelt, MD US
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20100272777 | OCULAR THERAPEUTIC AGENT DELIVERY DEVICES AND METHDOS FOR MAKING AND USING SUCH DEVICES - Ocular implant devices ( | 10-28-2010 |
Hyun K. Kim, Bethesda, MD US
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20090023695 | METHOD OF MAKING AND USING 7alpha,11beta-DIMETHYL-17beta-HYDROXYESTR-4-EN-3-ONE 17-UNDECANOATE - Methods of using 7α,11β-dimethyl-17β-hydroxy-4-estren-3-one bucyclate (I) and 7α,11β-dimethyl-17β-hydroxyestr-4-en-3-one 17-undecanoate (II) | 01-22-2009 |
Hyun Mun Kim, Rockville, MD US
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20080212686 | METHOD OF REDUCING A BLOCKING ARTIFACT WHEN CODING MOVING PICTURE - A method of coding a moving picture is provided that reduces blocking artifacts. The method can include defining a plurality of defining pixels S | 09-04-2008 |
20100086058 | METHOD OF REDUCING A BLOCKING ARTIFACT WHEN CODING MOVING PICTURE - A method of coding a moving picture is provided that reduces blocking artifacts. The method can include defining a plurality of defining pixels S | 04-08-2010 |
20150156514 | Method of Reducing a Blocking Artifact When Coding Moving Picture - A method of coding a moving picture is provided that reduces blocking artifacts. The method can include defining a plurality of defining pixels S | 06-04-2015 |
Jae Min Kim, Clarksburg, MD US
Patent application number | Description | Published |
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20140275129 | TETRAHYDROISOQUINOLIN-2-YL-(QUINAZOLIN-4-YL)METHANONE COMPOUNDS - Tetrahydroisoquinolin-2-yl-(quinazolin-4-yl)methanone derivatives represented by formula (I), pharmacologically acceptable salts thereof, and compositions containing such compounds are described. Methods for treating hyperproliferative disorders by administering the compounds are also described. 1,2,3,4-tetrahydroisoquinoline derivatives for making tetrahydroisoquinolin-2-yl-(quinazolin-4-yl)methanone compounds are also described. | 09-18-2014 |
Jae Ouk Kim, Rockville, MD US
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20090214510 | Broad Spectrum Antiviral Compositions - The instant invention provides compositions and methods for the treatment of viral infections caused by enveloped viruses comprising phospholipase nucleic acid molecules or polypeptides, or fusion molecules comprising phospholipase molecules or functional fragments thereof. | 08-27-2009 |
Jean Kim, Baltimore, MD US
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20110305689 | TREATMENT OF CHRONIC INFLAMMATORY RESPIRATORY DISORDERS - This invention relates, e.g., to a method for treating a subject having a chronic inflammatory respiratory disorder, comprising administering to the subject an effective amount of an inhibitor of the expression of and/or the activity of VEGF-A and/or VEGFR1 and/or VEGFR2 and/or NP1, or a combination thereof. Also described are screeing assays for agents for treating a subject having a chronic inflammatory respiratory disorder, and kits for performing one of the methods of the invention. | 12-15-2011 |
Jeonggoo Kim, Laurel, MD US
Patent application number | Description | Published |
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20080254235 | Pulsed laser deposition of high quality photoluminescent GaN films - High quality GaN films exhibiting strong room temperature blue photoluminescence with negligible impurity emissions are grown by a Pulsed Laser Deposition process in which process parameters are controlled to attain plasma particle energy of a target material plume directed from the target on the substrate structure below 5 eV at the deposition surface. Among the process parameters, a distance between the deposition surface and the target, a pressure level of the reaction gas in the processing chamber, and an energy density of the pulsed laser beam directed to the target are controlled, in combination, to attain the required low plasma particle energy of the plume below 5 eV in vicinity of the deposition surface. | 10-16-2008 |
20090078202 | SUBSTRATE HEATER FOR MATERIAL DEPOSITION - A radiative heater for substrates in a physical vapor deposition process for fabricating films of materials in a wide dynamic range of process temperatures and gas pressures includes a heat radiating member made from a high-temperature and oxidation resistant material tolerant to vacuum conditions which separates a heater volume containing heating filaments from a process volume which contains a deposition substrate heated by radiation of the walls of the heat radiating member. The heating elements extend through the body of the heat radiating member as well as in proximity to its surface to provide delivery of the heat to the substrate. The heat radiating member is shaped to form a cavity containing the substrate. The walls of the cavity envelope the substrate and radiate heat towards the substrate. Alternatively, the substrate is adhered to the flat surface of the heat radiating member. | 03-26-2009 |
20110027928 | PULSED LASER DEPOSITION OF HIGH QUALITY PHOTOLUMINESCENT GaN FILMS - High quality GaN films exhibiting strong room temperature blue photoluminescence with negligible impurity emissions are grown by a Pulsed Laser Deposition process in which process parameters are controlled to attain plasma particle energy of a target material plume directed from the target on the substrate structure below 5 eV at the deposition surface. Among the process parameters, a distance between the deposition surface and the target, a pressure level of the reaction gas in the processing chamber, and an energy density of the pulsed laser beam directed to the target are controlled, in combination, to attain the required low plasma particle energy of the plume below 5 eV in vicinity of the deposition surface. | 02-03-2011 |
Jeong H. Kim, Potomac, MD US
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20150229695 | METHODS AND APPARATUS FOR REDUCING LATENCY SHIFT IN SWITCHING BETWEEN DISTINCT CONTENT STREAMS - A method comprises receiving content from a source, and generating multiple content streams each comprising the received content. Each content stream includes segments comprising respective portions of the received content. Different segmenting is utilized in generating respective ones of the content streams such that the segments in each of the content streams are offset in time relative to corresponding segments in the other ones of the streams. For example, generating the multiple content streams may comprise segmenting n content streams such that each content stream comprises segments of length Ts with corresponding segments in adjacent ones of the content streams being offset from one another by an offset Tg. Such an arrangement ensures that latency shift upon switching between one of the content streams and another content stream in a different set of multiple content streams at a client device can be limited to a value approximated by Tg. | 08-13-2015 |
20160080830 | METHODS AND APPARATUS FOR CONTENT INTERACTION - A method comprises receiving content from at least one source, processing the content to identify an object in the content, assigning an identifier to the object based on the processing, permitting viewer selection of the object identifier, and providing additional information for presentation to a viewer of the content responsive to viewer selection of the object identifier. The content in some embodiments comprises live video from at least one live video source. For example, the content may comprise at least a portion of a panoramic video comprising a combination of multiple live videos from respective ones of a plurality of video sources. The panoramic video may be digitally cropped and scaled before a resulting version of the content is provided for presentation to the viewer. A plurality of different digitally cropped and scaled versions of the content from the panoramic video can be generated and made available to the viewer. | 03-17-2016 |
Jerome Kim, Fort Detrick, MD US
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20140248311 | N-TERMINAL DELETED GP120 IMMUNOGENS - The present invention relates, in general, to human immunodeficiency virus (HIV), and in particular to a vaccine for HIV-1 and to methods of making and using same. | 09-04-2014 |
20140302062 | HERPES SIMPLEX VIRUS - The present invention relates, in general to herpes simplex virus (HSV) and, particular, to antibodies that are specific for glycoprotein D (gD) of HSV. The invention also relates to prophylactic and therapeutic uses of such antibodies. | 10-09-2014 |
20140335126 | V1V2 IMMUNOGENS - The present invention relates, in general, to human immunodeficiency virus (HIV), and in particular to a vaccine for HIV-1 and to methods of making and using same. | 11-13-2014 |
20150239961 | ADCC-MEDIATING ANTIBODIES, COMBINATIONS AND USES THEREOF - The present invention relates, in general, to antibody-dependent cellular cytoxicity (ADCC)-mediating antibodies, and, in particular, to ADCC-mediating antibodies (and fragments thereof) suitable for use, for example, in reducing the risk of HIV-1 infection in a subject. The invention further relates to compositions comprising such antibodies or antibody fragments. | 08-27-2015 |
20160115205 | POLYVALENT HIV-1 IMMUNOGEN - The present invention relates, in general, to human immunodeficiency virus-1 (HIV-1) particular, to a polyvalent vaccine for HIV-1 and to methods of making and using same. | 04-28-2016 |
Jerome H. Kim, Bethesda, MD US
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20120308593 | Immunological Compositions for HIV - The disclosure relates to immunological compositions for vaccinating human beings against infection by the Human Immunodeficiency Virus (HIV). | 12-06-2012 |
John J. Kim, Baltimore, MD US
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20150073516 | Evaporative Therapeutic Hypothermia Device - The present invention provides a low-cost, low-power therapeutic hypothermia device for use in developing nations. The device includes a first and second receptacle separated by a space filled with a porous material such as sand. A cooling chemical can also be added to the porous material in order to speed cooling. Water is added to the porous material and a neonate is placed into the device for therapeutic hypothermia treatment. The neonate is monitored carefully using temperature sensors and a feedback system integrated into the device. Cooling can be modulated and/or warming commenced by adding Styrofoam blocks to raise the neonate off the surface of the device. | 03-12-2015 |
Joseph Iibong Kim, Frederick, MD US
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20130074338 | PRE-COMPRESSED SEAL INCLUDING REMOVABLE PRE-COMPRESSION MEMBER - A seal is provided that includes a resilient, arc-shaped body having a pair of sealing portions movable between a pre-compressed state and a compressed state. A removable pre-compression member slidingly engages the seal body along at least a portion of its length to hold the sealing portions in the pre-compressed state. In an embodiment, the seal body includes a pair of first retaining features and the pre-compression member includes a retaining portion having a pair of second retaining features that engage the pair of first retaining features to hold the sealing portions in the pre-compressed state. A strap portion extends from and between each retaining portion to allow the pre-compression member to flex during assembly of the seal to accommodate the radius of the seal body. | 03-28-2013 |
Joseph Ilbong Kim, Frederick, MD US
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20110304103 | PRE-COMPRESSED SEAL INCLUDING REMOVABLE PRE-COMPRESSION MEMBER - A seal is provided that includes a resilient, arc-shaped body having a pair of sealing portions movable between a pre-compressed state and a compressed state. A removable, arc-shaped pre-compression member slidingly engages the seal body along at least a portion of its length to hold the sealing portions in the pre-compressed state. | 12-15-2011 |
Jungho Kim, College Park, MD US
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20130190940 | OPTIMIZING AND CONTROLLING THE ENERGY CONSUMPTION OF A BUILDING - Described herein are methods and systems, including computer program products, for optimizing and controlling the energy consumption of a building. A first computing device generates a set of thermal response coefficients for the building based on energy characteristics of the building and weather data associated with the location of the building. The first computing device predicts an energy response of the building based on the set of thermal response coefficients and forecasted weather associated with the location of the building. The first computing device selects minimal energy requirements of the building based on an energy consumption cost associated with the building. The first computing device determines one or more temperature set points for the building based on the energy response and the minimal energy requirements. The first computing device transmits the one or more temperature set points to a thermostat of the building. | 07-25-2013 |
20150192911 | OPTIMIZING AND CONTROLLING THE ENERGY CONSUMPTION OF A BUILDING - Described herein are methods and systems, including computer program products, for optimizing and controlling a building's energy consumption and comfort. A computing device receives measurements from a plurality of sensors, at least some of which are located inside the building, where the measurements include temperature readings and comfort characteristics. The computing device generates a set of thermal response coefficients based on energy characteristics of the building, the measurements from the sensors, and weather data associated with the building's location. The computing device predicts an energy response of the building based on the set of thermal response coefficients and forecasted weather. The computing device selects minimal energy requirements of the building based on an energy consumption cost associated with the building and determines energy control points based on the energy response and the minimal energy requirements. The computing device transmits the energy control points to comfort devices in the building. | 07-09-2015 |
Jung-Sik Kim, Clarksburg, MD US
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20130029865 | Stromal Antigen 2 (STAG2) Compositions and Methods - Compositions and methods related to stromal antigen 2 (STAG2) and its role in diverse human cancers, including nucleic acids, polypeptides, vectors, cells and cell lines. | 01-31-2013 |
20130216559 | Stromal Antigen 2 (STAG2) Compositions and Methods - Compositions and methods related to stromal antigen 2 (STAG2) and its role in diverse human cancers, including nucleic acids, polypeptides, vectors, cells and cell lines. | 08-22-2013 |
20140094384 | STROMAL ANTIGEN 2 (STAG2) COMPOSITIONS AND METHODS - Compositions and methods related to stromal antigen 2 (STAG2) and its role in diverse human cancers, including nucleic acids, polypeptides, vectors, cells and cell lines. | 04-03-2014 |
Jung-Whan Kim, Baltimore, MD US
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20090209618 | Pyruvate dehydrogenase kinases as therapeutic targets for cancer and ischemic diseases - The invention provides therapeutic and prophylactic compounds and methods for altering the activity of pyruvate dehydrogenase kinase (e.g. PDK1, PDK2, PDK3, PDK4). Such therapies are useful for the treatment of neoplasia. The invention further provides therapeutic and prophylactic compounds and methods of altering pyruvate dehydrogenase activity to treat or prevent cell death related to ischemia. | 08-20-2009 |
20150133524 | PYRUVATE DEHYROGENASE KINASES AS THERAEUTIC TARGETS FOR CANCER AND ISCHEMIC DISEASES - The invention provides therapeutic and prophylactic compounds and methods for altering the activity of pyruvate dehydrogenase kinase (e.g. PDK1, PDK2, PDK3, PDK4). Such therapies are useful for the treatment of neoplasia. The invention further provides therapeutic and prophylactic compounds and methods of altering pyruvate dehydrogenase activity to treat or prevent cell death related to ischemia. | 05-14-2015 |
Kunwoo Kim, Baltimore, MD US
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20140126732 | ACOUSTIC MONITORING SYSTEM AND METHODS - An electronic stethoscope includes an acoustic sensor assembly having a plurality of microphones arranged in an acoustic coupler to provide a plurality of pick-up signals. The electronic stethoscope also includes a detection system to communicate with the acoustic sensor assembly and to combine the plurality of pick-up signals to provide a detection signal. The electronic stethoscope also includes an output system to communicate with the detection system. The acoustic coupler uses a compliant material that forms an acoustically tight seal with a body under observation. | 05-08-2014 |
Kwang S. Kim, Reisterstown, MD US
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20100136027 | Methods and Compositions for Treating Bacterial Infection - The present invention relates to methods and compositions for the treatment of bacterial infection, for example extraintestinal | 06-03-2010 |
Kwang S. Kim, Baltimore, MD US
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20150148389 | Methods for Treating or Preventing Brain Infections - The invention is directed to methods of treating organ specific infections in a host organism by administering compounds that target host receptors and/or host cellular signaling molecules to prevent a pathogen from infecting the organ. For example, the administration of a compound to prevent a pathogen from crossing the blood-brain barrier to prevent a brain infection. | 05-28-2015 |
Kwang Sik Kim, Baltimore, MD US
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20110098333 | METHODS FOR TREATING OR PREVENTING BRAIN INFECTIONS - The invention is directed to methods of treating organ specific infections in a host organism by administering compounds that target host receptors and/or host cellular signaling molecules to prevent a pathogen from infecting the organ. For example, the administration of a compound to prevent a pathogen from crossing the blood-brain barrier to prevent a brain infection. | 04-28-2011 |
Matthew Jachyun Kim, Rockville, MD US
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20140349553 | Apparatus for and method of refurbishing a lacrosse ball - This invention relates to an apparatus and method for refurbishing lacrosse balls by using a fast, convenient, automated, entertaining, energy efficient, portable, and modular machine/method of removing a thin layer of rubber from the surface of a used lacrosse ball, by applying even pressure and random rotation of abrasive, one to four cups or rings, utilizing a combination of gravity and/or force of the cups against the surface of the ball, and the introduction of a solvent at various speeds, volume, and concentration, during and after the removal of a thin layer of rubber, to maximize the restoration of the rubber surface. | 11-27-2014 |
Michael Juhyun Kim, Rockville, MD US
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20140349553 | Apparatus for and method of refurbishing a lacrosse ball - This invention relates to an apparatus and method for refurbishing lacrosse balls by using a fast, convenient, automated, entertaining, energy efficient, portable, and modular machine/method of removing a thin layer of rubber from the surface of a used lacrosse ball, by applying even pressure and random rotation of abrasive, one to four cups or rings, utilizing a combination of gravity and/or force of the cups against the surface of the ball, and the introduction of a solvent at various speeds, volume, and concentration, during and after the removal of a thin layer of rubber, to maximize the restoration of the rubber surface. | 11-27-2014 |
Mina Kim, Baltimore, MD US
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20100286502 | FREQUENCY REFERENCING FOR CHEMICAL EXCHANGE SATURATION TRANSFER (CEST) MRI - A water saturation shift referencing (WASSR) technique performed using a magnetic resonance scanner comprises: acquiring a spatial map of Z spectra that encompass the water center frequency using sufficiently low saturation power and sufficiently acquisition short duration selected such that symmetry of the Z spectra is not obscured by magnetization transfer but dominated by direct water saturation effects so that the spectrum is substantially symmetric; and performing a symmetry analysis on the substantially symmetric Z spectra to generate a spatial map of the water center frequency. WASSR-corrected chemical exchange saturation transfer (CEST) imaging is disclosed as an illustrative example. | 11-11-2010 |
Moon S. Kim, Silver Spring, MD US
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20090087033 | Method and system for wholesomeness inspection of freshly slaughtered chickens on a processing line - An imaging system containing an electron-multiplying charge-coupled device detector and line-scan spectrograph is used for identifying wholesome and unwholesome freshly slaughtered chicken carcasses on high-speed commercial chicken processing lines. Multispectral imaging algorithms allow for real-time online identification of wholesome and unwholesome chicken carcasses. | 04-02-2009 |
20090185182 | Simultaneous Acquisition of Fluorescence and Reflectance Imaging Techniques with a Single Imaging Device for Multitask Inspection - A hyperspectral reflectance and fluorescence line-scan imaging system is used for on-line quality and safety inspection of agricultural commodities. The system simultaneously acquires hyperspectral/multispectral combinations of both fluorescence and reflectance images of the agricultural commodities. | 07-23-2009 |
20090309967 | Hand-held inspection tool and method - The hand-held inspection tool enhances the ability of an on-site inspector to detect and communicate the presence of contamination on an object or in an area. An on-site inspector directs an excitation light in the sensing head of the tool into an area of interest. If the targeted contamination is present, the excitation light causes the contamination to emit fluorescence. The emitted fluorescent light passes through a narrow spectral band-pass video camera filter and is detected by a video camera mounted in the tool sensing head. The video camera transmits the image to a display visible to the on-site inspector. The invention also includes a means of recording, documenting, and wirelessly communicating the inspection process so that remotely located personnel can view the inspection, and respond to the inspection findings in real time. | 12-17-2009 |
20120008835 | Method and System for Wholesomeness Inspection of Freshly Slaughtered Chickens on a Processing Line - An imaging system containing an electron-multiplying charge-coupled device detector and line-scan spectrograph is used for identifying wholesome and unwholesome freshly slaughtered chicken carcasses on high-speed commercial chicken processing lines. Multispectral imaging algorithms allow for real-time online identification of wholesome and unwholesome chicken carcasses. | 01-12-2012 |
Myeongseob Kim, Ellicott City, MD US
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20110130297 | QUANTUM DOT-SENSORY ARRAY FOR BIOLOGICAL RECOGNITION - The present invention provides a quantum dot-based biomolecule sensor array capable of differentiating the strain of a variety of biological molecules including bacteria, spores, fungi, viruses, and disease-causing prions. The biosensor uses specific chemical functionalities that regulate the interactions between different chemical ligands and biological molecules. | 06-02-2011 |
Myung Kim, Bethesda, MD US
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20080299128 | Effect of Bst2 on inflammation - The application disclose a method of preventing immune cells from binding to other cells, which includes contacting the immune cells and the other cells with a composition comprising Bst2 antagonist. | 12-04-2008 |
20100129365 | TREATMENT OF INFLAMMATION USING BST2 INHIBITOR - The application discloses a method of preventing immune cells from binding to other cells, which includes contacting the immune cells and the other cells with a composition comprising Bst2 antagonist. | 05-27-2010 |
Myung Kyung Kim, Bethesda, MD US
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20100130597 | DNA-PKCS MODULATES ENERGY REGULATION AND BRAIN FUNCTION - The invention relates to new functions of the DNA-PKcs gene product in energy metabolism, brain function and physical fitness. | 05-27-2010 |
Nancy Kim, Marriottsville, MD US
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20100211516 | METHOD AND SYSTEM FOR MATCHING EMPLOYERS WITH JOB-SEEKING INDIVIDUALS - A system for proactively marketing job openings via an employment clearinghouse in communication with employers and outreach organizations serving potential employees is provided. The employment clearinghouse provides information and services related to employment; receives one or more job openings from an employer; geocodes the one or more job openings to determine a location for each of the one or more job openings; determines, for each of the one or more job openings, one or more outreach organizations within a predetermined distance of the location determined for the job opening; and presents the received one or more job openings to the one or more determined outreach organizations. | 08-19-2010 |
20110258132 | METHOD AND SYSTEM FOR MATCHING EMPLOYERS WITH JOB-SEEKING INDIVIDUALS - A system for proactively marketing job openings via an employment clearinghouse in communication with employers and outreach organizations serving potential employees is provided. The employment clearinghouse provides information and services related to employment; receives one or more job openings from an employer; geocodes the one or more job openings to determine a location for each of the one or more job openings; determines, for each of the one or more job openings, one or more outreach organizations within a predetermined distance of the location determined for the job opening; and presents the received one or more job openings to the one or more determined outreach organizations. | 10-20-2011 |
Nicole Jurie Kim, Potomac, MD US
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20100134863 | PORTABLE ELECTRONIC DEVICE WITH AN INTEGRATED SWITCHABLE MIRROR - Electronic devices with displays having switchable mirrors are described. The switchable mirror covers the display and is capable of switching from a transparent state to a reflecting state responsive to a switch in the electronic device. In one embodiment, the display is switched off when the switchable mirror switches to its reflecting state. In another embodiment, the switchable mirror is switched to its reflecting state when the electronic device is switched off. | 06-03-2010 |
Robert Kim, Baltimore, MD US
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20150073516 | Evaporative Therapeutic Hypothermia Device - The present invention provides a low-cost, low-power therapeutic hypothermia device for use in developing nations. The device includes a first and second receptacle separated by a space filled with a porous material such as sand. A cooling chemical can also be added to the porous material in order to speed cooling. Water is added to the porous material and a neonate is placed into the device for therapeutic hypothermia treatment. The neonate is monitored carefully using temperature sensors and a feedback system integrated into the device. Cooling can be modulated and/or warming commenced by adding Styrofoam blocks to raise the neonate off the surface of the device. | 03-12-2015 |
Sangsoo Kim, Gaithersburg, MD US
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20140120157 | TARGETED LIPOSOMES - The present invention is in the field of drug delivery, and specifically, cationic liposome-based drug delivery. In embodiments, this invention provides methods of making ligand-targeted (e.g., antibody- or antibody fragment-targeted) liposomes useful for the delivery of liposomes to tumors, including brain tumors. In embodiments, the liposomes deliver temozolomide across the blood-brain barrier for treatment of primary or metastatic brain tumors. Additional cancers that can be treated with the liposomes include neuroendocrine tumors, melanoma, prostate, head and neck, ovarian, lung, liver, kidney, breast, urogenital, gastric, colorectal, cervical, vaginal, angiosarcoma, liposarcoma, rhabdomyosarcoma, choriocarcinoma, pancreatic, retinoblastoma and other types of cancer. In another embodiment the liposomes deliver melphalan for the treatment of multiple myeloma, other tumors of the blood or other solid tumors. In still other embodiments the liposomes can deliver other drugs such as pemetrexed or irinotecan for treatment of cancer or drugs including atropine for treatment of organophosphate poisoning. | 05-01-2014 |
Sangwon Kim, Baltimore, MD US
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20090304596 | Methods for Predicting Psychotropic Drugs Which Elicit Weight Gain - The atypical antipsychotic drugs (AAPDs) have markedly enhanced the treatment of schizophrenias but their use has been hindered by the major weight gain elicited by some AAPDs. We found that orexigenic AAPDs potently and selectively activate hypothalamic AMP kinase (AMPK), an action abolished in mice with deletion of histamine H1 receptors. These findings afford a means of developing better therapeutic agents and provide insight into the hypothalamic regulation of food intake. | 12-10-2009 |
Scott C. Kim, Glen Burnie, MD US
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20140119481 | SYMBOL TIMING RECOVERY WITH MULTI-CORE PROCESSOR - A method of performing timing error detection includes receiving, by a multi-core processor, a data stream and up-sampling the data stream by a plurality of processing cores of the multi-core processor. The up-sampling is performed in parallel by the plurality of processing cores. The method includes selecting one sample per symbol of the data stream to generate a sampled data output. The method also includes performing symbol timing recovery based on the sampled data output to adjust a resampling point. | 05-01-2014 |
Seon Woo Kim, Elkridge, MD US
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20100120106 | Process for producing lower alkyl alcohols from cellulosic biomass using microorganisms - At least one isolated microorganism, which converts at least 10% by weight, and preferably 50% by weight, of cellulosic biomass to a lower alkyl alcohol by direct digestion, and which produces at least 4% by volume of the lower alkyl alcohol in an aqueous-based digestion medium. | 05-13-2010 |
20140148621 | PROCESS TO PRODUCE ORGANIC COMPOUNDS FROM SYNTHESIS GASES - At least one isolated microorganism and a fermentation method to convert hydrogen gas, carbon dioxide gas, and/or carbon monoxide gas to a lower alkyl alcohol and/or carboxylic acid and to produce at least 2% by volume of the lower alkyl alcohol or carboxylic acid in an aqueous-based medium. | 05-29-2014 |
Seon-Woo Kim, Ellicott City, MD US
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20120034664 | PROCESS TO PRODUCE ORGANIC COMPOUNDS FROM SYNTHESIS GASES - At least one isolated microorganism and a fermentation method to convert hydrogen gas, carbon dioxide gas, and/or carbon monoxide gas to a lower alkyl alcohol and/or carboxylic acid and to produce at least 2% by volume of the lower alkyl alcohol or carboxylic acid in an aqueous-based medium. | 02-09-2012 |
20120270288 | PROCESS TO PRODUCE ORGANIC COMPOUNDS FROM SYNTHESIS GASES - At least one isolated microorganism and a fermentation method to convert hydrogen gas, carbon dioxide gas, and/or carbon monoxide gas to a lower alkyl alcohol and/or carboxylic acid and to produce at least 2% by volume of the lower alkyl alcohol or carboxylic acid in an aqueous-based medium. | 10-25-2012 |
Seon-Woo Kim, Columbia, MD US
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20160017378 | Process for producing lower alkyl alcohols from cellulosic biomass using microorganisms - At least one isolated microorganism, which converts at least 10% by weight, and preferably 50% by weight, of cellulosic biomass to a lower alkyl alcohol by direct digestion, and which produces at least 4% by volume of the lower alkyl alcohol in an aqueous-based digestion medium. | 01-21-2016 |
Silvia R. Kim, Bethesda, MD US
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20150211063 | Methods of Screening for Susceptibility to Virus Infection - The invention is directed to methods for screening the resistance of CD4+ cells to viral infection, in particular human immunodeficiency virus (HIV) infection. | 07-30-2015 |
Sung Min Kim, Towson, MD US
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20150202014 | Surgical Robot System and Surgical Robot Control Method - Disclosed are a surgical robot system and a surgical robot control method. The surgical robot system includes a surgical tool configured to perform surgery on each of a plurality of procedure regions in a surgical region which is divided into the plurality of procedure regions, a robot arm on which the surgical tool is mounted, and a driver configured to operate the robot arm. The present invention adjusts a speed at which a surgical robot moves, based on a risk level which is set for a procedure region, and thus enhances a stability of surgery performed by the surgical robot and moreover decreases a degree to which the surgery is delayed, thereby reducing pain and inconvenience caused to an operator and a patient. | 07-23-2015 |
Sung Soo Kim, Perry Hall, MD US
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20130038353 | SYSTEM AND METHOD FOR SIMULATING BIOFIDELIC SIGNALS - A system for simulating biofidelic signals includes a transducer and a neural transmitter port. The transducer is affected by a parameter and provides an alternating electrical signal based on an effect of the parameter. The neural transmitter port receives a processed electrical signal and outputs the processed electrical to a neural transmitter. The system further includes an input portion, a band-pass filter, and an integrate-and-fire mechanism. The input portion outputs a first signal based on the alternating electrical signal. The band-pass filter outputs a first filtered signal based on the first signal. The integrate-and-fire mechanism generates the processed electrical signal based on the first filtered signal. | 02-14-2013 |
Un-Kyung Kim, Gaithersburg, MD US
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20080227093 | PHENYLTHIOCARBAMIDE (PTC) TASTE RECEPTOR - The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor. | 09-18-2008 |
20100035340 | VARIANTS OF HUMAN TASTE RECEPTOR GENES - Identified herein are different forms of bitter receptor genes that occur in different humans. These alleles are generated by numerous coding single nucleotide polymorphisms (cSNP's) that occur within the members of the T2R gene family. Some SNP's cause amino acid substitutions, while others introduce chain termination codons, rendering the allele non-functional. Differences in these genes are believed to have a large effect on those individuals' sense of bitter taste, such that these individuals perceive the taste of bitter substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define large groups and populations who perceive bitter tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level for the first time. | 02-11-2010 |
20100151476 | PHENYLTHIOCARBAMIDE (PTC) TASTE RECEPTOR - The invention provides isolated nucleic and amino acid sequences of a taste cell receptor that serves as a sensor for the bitter taste of phenylthiocarbamide (PTC), antibodies to such PTC taste receptor, methods of detecting such nucleic and amino acid sequences, and methods of screening for modulators of such PTC taste receptor. | 06-17-2010 |
Yeong Sang Kim, Gaithersburg, MD US
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20120283215 | PHARMACEUTICAL COMPOSITIONS WHICH INHIBIT FKBP52-MEDIATED REGULATION OF ANDROGEN RECEPTOR FUNCTION AND METHODS OF USING SAME - Pharmaceutical compositions that bind to a predicted FK506 Binding Protein 52 (FKBP52) interaction surface on the androgen receptor hormone binding domain, otherwise known as FKBP52 Targeting Agents (FTAs) are provided. These compositions of the present invention are found to specifically recognize the FKBP52 regulatory surface on the androgen receptor and inhibit FKBP52 from functionally interacting with the androgen receptor. Compositions comprising the pharmaceutical composition, as well as methods of use, treatment and screening are also provided. | 11-08-2012 |
20140171503 | NUCLEAR RECEPTOR MODULATORS AND THEIR USE FOR THE TREATMENT AND PREVENTION OF CANCER - Disclosed are compounds which are nuclear receptor modulators that can act as antagonists to the androgen receptor, for example, a compound of Formula I: wherein R | 06-19-2014 |
Yeounjin Kim, Germantown, MD US
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20090035299 | Methods and compositions for treating diseases targeting MABA1 - Methods and compositions for diagnosing, detecting and treating a colon disease associated with differential expression of MABA1 in comparison to healthy cells. Also provided are antagonists or agonists of MABA1, and methods for screening agents that modulate the MABA1 level or activity in vivo or in vitro. | 02-05-2009 |
20100239581 | KIDNEY DISEASE TARGETS AND USES THEREOF - The present invention provides a method for diagnosing and detecting diseases associated with kidney. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in kidney diseases (KCAT) and antibodies binds to KCATs. The present invention provides that KCATs are used as targets for screening agents that modulates the KCAT activities. Further the present invention provides methods for treating diseases associated with kidney. | 09-23-2010 |
20110271357 | COLON DISEASE TARGETS AND USES THEREOF - The present invention provides a method for diagnosing and detecting diseases associated with colon. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in colon diseases (CCAT) and antibodies binds to CCAT. The present invention provides that CCAT is used as targets for screening agents that modulates the CCAT activities. Further the present invention provides methods for treating diseases associated with colon. | 11-03-2011 |
20120183552 | KIDNEY DISEASE TARGETS AND USES THEREOF - The present invention provides a method for diagnosing and detecting diseases associated with kidney. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in kidney diseases (KCAT) and antibodies binds to KCATs. The present invention provides that KCATs are used as targets for screening agents that modulates the KCAT activities. Further the present invention provides methods for treating diseases associated with kidney. | 07-19-2012 |
20130111613 | COLON DISEASE TARGETS AND USES THEREOF | 05-02-2013 |
20150125456 | COLON DISEASE TARGETS AND USES THEREOF - The present invention provides a method for diagnosing and detecting diseases associated with colon. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in colon diseases (CCAT) and antibodies binds to CCAT. The present invention provides that CCAT is used as targets for screening agents that modulates the CCAT activities. Further the present invention provides methods for treating diseases associated with colon. | 05-07-2015 |
Yeounjin Kim, Gemantown, MD US
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20100172908 | METHODS AND COMPOSITIONS FOR TREATING DISEASES TARGETING MABA1 - Methods and compositions for diagnosing, detecting and treating a colon disease associated with differential expression of MABA1 in comparison to healthy cells. Also provided are antagonists or agonists of MABA1, and methods for screening agents that modulate the MABA1 level or activity in vivo or in vitro. | 07-08-2010 |
Yong Chan Kim, Rockville, MD US
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20130157363 | METHODS OF PRODUCING T CELL POPULATIONS ENRICHED FOR STABLE REGULATORY T-CELLS - The present invention provides methods for producing cell populations enriched for stable, regulatory T cells (Tregs). In particular, the invention relates to methods for culturing T cells such that the final culture is enriched for stable, regulatory T cells. It also relates to methods for stabilizing regulatory T cells. Also provided are compositions enriched for stable, regulatory T cells, which are useful for treating individuals in need of such treatment. The methods and compositions disclosed herein can also be used to treat an individual suffering from an immune-mediated disease. | 06-20-2013 |
Youngmin Kim, College Park, MD US
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20090092314 | Method, system and apparatus for determining and modifying saliency of a visual medium - A method, system and apparatus for determining and modifying saliency of a visual medium are provided. The method, system and apparatus may obtain saliency values for a visual medium based on a plurality of visual channels. The saliency values may be obtained based on at least one of computer-generated modeling, user-specified input and eye-tracking. The method, system and apparatus may aggregate the obtained saliency values and classify regions of the visual medium based on the aggregated saliency values. The visual channels may include one or more of absolute mean curvature, a gradient of mean curvature, a gradient of color intensity, color luminance, color opponency, color saturation, lighting and focus. When calculating mean curvature, the method, system and apparatus may calculate a change in mean curvature for a plurality of vertices around a region and displace the vertices in accordance with the calculated change in mean curvature to change a saliency of the region. | 04-09-2009 |
Young Wook Kim, Beltsville, MD US
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20140199757 | ATOMIC LAYER DEPOSITION INVERTED PASSIVATED SURFACE ACOUSTIC WAVE SENSOR FOR EARLY DETECTION OF BIOFILM GROWTH - A surface acoustic wave (SAW) biofilm sensor includes a transmitting electric to acoustic wave transducer defining an upper surface and a lower surface, a receiving acoustic wave to electric transducer defining an upper surface and a lower surface, a piezoelectric film layer defining an upper surface and a lower surface, and a passivation film layer defining an upper surface and a lower surface. Portions of the lower surface of the piezoelectric film layer are disposed on the upper surface of the transmitting electric to acoustic wave transducer and on the upper surface of the receiving acoustic wave to electric transducer, and the lower surface of the passivation film layer is disposed on the upper surface of the piezoelectric film layer such that the upper surface of the passivation film layer is configured to enable contact with a biofilm. | 07-17-2014 |