Bizzarri, IT
Cinzia Bizzarri, L'Aquila IT
Patent application number | Description | Published |
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20090093530 | (2R)-2-[4-Sulfonyl) Aminophenyl] Propanamides and Pharmaceutical Compositions Containing Them - The present invention relates to novel (2R)-2-phenylpropanamides bearing a 4-sulfonylamino substituent on the 4 position of the phenyl group and to pharmaceutical compositions containing them, which are used as inhibitors of the chemotaxis of polymorphonucleate and mononucleate cells, and which are useful in the treatment of various ELR+CXC chemokine-mediated disorders. In particular, the compounds of the invention are useful in the treatment and control of specific CXCR2 dependent pathologies such as BOS, COPD, angiogenesis and melanoma. | 04-09-2009 |
20090131441 | Metabolites Of 2-Arylpropionic Acid Derivatives And Pharmaceutical Compositions Containing Them - Metabolites of 2-(R)-4-isobutylarylpropionamides and pharmaceutical compositions containing such compounds are useful in inhibiting the chemotactic activation of neutrophils (PMN leukocytes) induced by the interaction of Interleukin-8 (IL-8) with CXCR1 and CXCR2 membrane receptors. The compounds are used for the prevention and treatment of pathologies deriving from said activation. Notably, these metabolites are devoid of cyclo-oxygenase inhibition activity and are particularly useful in the treatment of neutrophil-dependent pathologies such as psoriasis, ulcerative colitis, melanoma, chronic obstructive pulmonary disease (COPD), bullous pemphigoid, rheumatoid arthritis, idiopathic fibrosis, glomerulonephritis and in the prevention and treatment of damages caused by ischemia and reperfusion. | 05-21-2009 |
20090203652 | CHIRAL ARYLKETONES IN THE TREATMENT OF NEUTROPHIL-DEPENDENT INFLAMMATORY DISEASES - The compounds of formula (I): | 08-13-2009 |
20100152256 | (2R)-2-[(4-sulfonyl) aminophenyl] propanamides and pharmaceutical compositions containing them - The present invention relates to novel (2R)-2-phenylpropanamides bearing a 4-sulfonylamino substituent on the 4 position of the phenyl group and to pharmaceutical compositions containing them, which are used as inhibitors of the chemotaxis of polymorphonucleate and mononucleate cells, and which are useful in the treatment of various ELR+CXC chemokine-mediated disorders. In particular, the compounds of the invention are useful in the treatment and control of specific CXCR2 dependent pathologies such as BOS, COPD, angiogenesis and melanoma. | 06-17-2010 |
20100267726 | 2-ARYL-ACETIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Selected 2-arylacetic acids, their derivatives and pharmaceutical compositions that contain these compounds are useful in inhibiting chemotactic activation of neutrophils (PMN leukocytes) induced by the interaction of Interleukin-8 (IL-8) with CXCR1 and CXCR2 membrane receptors. The compounds are used for the prevention and treatment of pathologies deriving from said activation. In particular, 2(ortho)-substituted arylacetic acids or their derivatives, such as amides and sulfonamides, lack cyclo-oxygenase inhibition activity and are particularly useful in the treatment of neutrophil-dependent pathologies such as psoriasis, ulcerative colitis, melanoma, chronic obstructive pulmonary disease (COPD), bullous pemphigoid, rheumatoid arthritis, idiopathic fibrosis, glomerulonephritis and in the prevention and treatment of damages caused by ischemia and reperfusion. | 10-21-2010 |
20110195967 | 2-ARYL-ACETIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Selected 2-arylacetic acids, their derivatives and pharmaceutical compositions that contain these compounds are useful in inhibiting chemotactic activation of neutrophils (PMN leukocytes) induced by the interaction of Interleukin-8 (IL-8) with CXCR1 and CXCR2 membrane receptors. The compounds are used for the prevention and treatment of pathologies deriving from their activation. In particular, 2(ortho)-substituted arylacetic acids or their derivatives, such as amides and sulfonamides, lack cyclo-oxygenase inhibition activity and are particularly useful in the treatment of neutrophil-dependent pathologies such as psoriasis, ulcerative colitis, melanoma, chronic obstructive pulmonary disease (COPD), bullous pemphigoid, rheumatoid arthritis, idiopathic fibrosis, glomerulonephritis and in the prevention and treatment of damages caused by ischemia and reperfusion. | 08-11-2011 |
20130079514 | "OMEGA-AMINOALKYLAMIDES OF R-2-ARYL-PROPIONIC ACIDS ASINHIBITORS OF THE CHEMOTAXIS OF POLYMORPHONUCLEATE ANDMONONUCLEATE CELLS" - (R)-2-Arylpropionamide compounds of formula (I), pharmaceutical preparations of the compounds and a process for making the compounds are described. | 03-28-2013 |
Cinzia Bizzarri, L' Aquila IT
Patent application number | Description | Published |
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20080312293 | 2-Arylpropionic Acid Derivatives and Pharmaceutical Compositions Containing Them - The present invention relates to selected (R)-2-phenyl-propionamides and (R)-2-phenyl-sulfonamides with a hydrogen bond acceptor atom/group in a well defined position in the chemical space. These compounds show a surprising potent inhibitory effect on C5a induced human PMN chemotaxis. The compounds of the invention absolutely lack of CXCL8 inhibitory activity. Said compounds are useful in the treatment of pathologies depending on the chemotactic activation of neutrophils and monocytes induced by the fraction C5a of the complement. In particular, the compounds of the invention are useful in the treatment of sepsis, psoriasis, rheumatoid arthritis, ulcerative colitis, acute respiratory distress syndrome, idiopathic fibrosis, glomerulonephritis and in the prevention and treatment of injury caused by ischemia and reperfusion. | 12-18-2008 |
Marco Bizzarri, Sassoferrato (an) IT
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20150215335 | DETECTING AND PREVENTING EXECUTION OF SOFTWARE EXPLOITS - In non-limiting examples, anti-exploit systems and methods described herein monitor a memory space of a process for execution of functions. Stack walk processing is executed upon invocation of one of the functions in the monitored memory space. During execution of the stack walk processing, at least one memory check is performed to detect suspicious behavior. An alert of suspicious behavior is triggered when the performing of the memory check detects at least one of: code execution attempted from non-executable memory, identification of an invalid base pointer, identification of an invalid stack return address, attempted execution of a return-oriented programming technique, the base pointer is outside a current thread stack, and a return address is detected as being inside a virtual memory area. If an alert of suspicious behavior is triggered, execution of a payload is prevented for the invoked function. | 07-30-2015 |
Mauro Costa Bizzarri, Anzola Dell Emilia IT
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20140034032 | SMART IGNITION COIL WITH INTEGRATED CONTROLLER - Disclosed is a device comprising an ignition coil, a power stage and a controller connected to said ignition coil via said power stage. The controller is adapted to receive commands and/or parameters related to engine operation and to process said commands and/or parameters and the controller is further adapted to output a voltage signal to said ignition coil via said power stage, said signal being based at least in part on said processed commands and/or parameters. | 02-06-2014 |
Pier Giuseppe Bizzarri, San Benedetto Del Tronto IT
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20150016603 | DEVICE AND METHOD FOR MANAGING ELECTRONIC FACILITIES OF BUILDINGS - A device and a method for managing electronic facilities of buildings. The device may include one or more interface elements for connecting the device to one or more electronic facilities of a building, a connection element for the connection of a portable storage device, and a control unit for reading files from the portable storage device, in which the reading of the files from the portable storage device is based on cryptography techniques, and in which the control unit is adapted to operate the electronic facilities by means of the interface elements on the basis of the result of the reading of the files from the portable storage device. The device according to the present disclosure enables a user to manage various types of electronic facilities of buildings simultaneously in a simple manner and by using a single portable storage device. | 01-15-2015 |
Simone Bizzarri, Torino IT
Patent application number | Description | Published |
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20080214186 | System for Monitoring the Quality of Service in a Communication Network - Monitoring system includes a set of peripheral monitoring agents including processing functionalities housed in SIMS. Such processing functionalities, depending at least on operating conditions of each terminal and its respective SIMS, are able to adaptively establish a distribution of measuring functionalities included in the peripheral monitoring agents between the terminal itself (for example storing them in the related memory or multimedia card) and its respective SIM. | 09-04-2008 |
20080311901 | Method and Apparatus for Evaluating the Performance of a Radiomobile Transmission System - A method for evaluating the performance of a radiomobile system including a core network, includes the steps of generating a signal through a first device and transmitting the signal to a second device through the core network, wherein the transmission step includes emulating a radio access network interposed between the first device and the core network. | 12-18-2008 |