Patent application number | Description | Published |
20080206772 | SAMPLE TREATMENT SOLUTION AND REAGENT KIT FOR PREPARING SAMPLE FOR DETECTING DNA METHYLATION - The present invention provides a sample treatment solution for preparing a sample for DNA methylation which can achieve stable detection results in detection of DNA methylation and be easily pretreated, comprising an aqueous solution containing a protease. | 08-28-2008 |
20090123923 | Method for obtaining information regarding quantity of DNA after non-methylated cytosine converting treatment in analysis of DNA methylation - The present invention provides an easy and accurate method for obtaining information regarding a quantity of DNA included in a sample used for analyzing a methylation of a target DNA, comprising steps of: treating a biological sample containing DNA including the target DNA with a non-methylated cytosine converting agent for converting non-methylated cytosine of the DNA into another base; and obtaining information regarding a quantity of DNA included in the sample treated in the treating step by using an oligonucleotide complementary to a cytosine-free region of the target DNA. | 05-14-2009 |
20100240042 | METHOD OF DETECTING METHYLATED CYTOSINE - The method for detecting a methylated cytosine of the present invention comprises the steps of: | 09-23-2010 |
20110027799 | KIT AND METHOD FOR DETERMINING WHETHER OR NOT UNMETHYLATED CYTOSINE CONVERSION TREATMENT IS PROPERLY CARRIED OUT AND METHOD FOR ANALYZING METHYLATED DNA USING THE SAME - Success or failure of unmethylated cytosine conversion treatment is determined by using a first primer set comprising plural primers that hybridize with a nucleic acid comprising a nucleotide sequence not containing cytosine in the nucleotide sequence of biological DNA that is subject to an unmethylated cytosine conversion treatment and a second primer set comprising plural primers that hybridize with a nucleic acid comprising a nucleotide sequence in which cytosine in a nucleotide sequence containing cytosine and not containing a CpG site is converted into a base other than cytosine, in the nucleotide sequence of biological DNA. | 02-03-2011 |
20110177511 | METHOD FOR DETERMINING BREAST CANCER METASTASIS AND METHOD FOR EVALUATING SERUM - It is determined that the breast cancer has metastasized when methylation is detected in the CpG island of at least one selected from the group consisting of GSTP1, RASSF1A and RARb by detecting methylation in CpG island of each of GSTP1, RASSF1A and RARb contained in serum obtained from a patient who has undergone surgery to remove breast cancer. | 07-21-2011 |
Patent application number | Description | Published |
20090130680 | SOLID SUPPORT - The present invention provides a solid support for performing steps of isolation of cell or extraction and purification of nucleic acid, safely, easily, efficiently, and with high yield in the genetic test for investigating the presence of pathogenic bacterial infection. A solid support for binding with cell as an embodiment of the above-described solid support, comprises a polypeptide having capability of binding with mycolic acid-containing glycolipid which is immobilized on the surface of a carrier. In addition, a solid support for binding with nucleic acid as another embodiment of the above-described solid support, comprises a polypeptide having capability of binding with nucleic acid which is immobilized on the surface of a carrier. | 05-21-2009 |
20110224420 | SOLID SUPPORT - The present invention provides a solid support for performing steps of isolation of cell or extraction and purification of nucleic acid, safely, easily, efficiently, and with high yield in the genetic test for investigating the presence of pathogenic bacterial infection. A solid support for binding with cell as an embodiment of the above-described solid support, comprises a polypeptide having capability of binding with my colic acid-containing glycolipid which is immobilized on the surface of a carrier. In addition, a solid support for binding with nucleic acid as another embodiment of the above-described solid support, comprises a polypeptide having capability of binding with nucleic acid which is immobilized on the surface of a carrier. | 09-15-2011 |
20140324904 | SIMILAR DESIGN STRUCTURE SEARCH DEVICE AND SIMILAR DESIGN STRUCTURE SEARCH METHOD - Provided is design assistance technology capable of performing filtered detection on the basis of similar assembly structures when referencing past defect information and design improvement information at a design stage. In a similar design structure search device for an assembly configured by a plurality of components, the device has means for: acquiring component features of each component and adjacency relationships among components on the basis of 3D CAD data of an assembly configured by a plurality of components in order to store the same, as assembly structure data, together with past defect cases, design improvement cases, and manufacture instruction cases; and generating the assembly structure data on the basis of the 3D CAD data to be evaluated so that, when retrieving assembly structures similar to the stored case data, filtered detection is performed on the basis of a similarity assessment of two steps for component features and adjacency relationships. | 10-30-2014 |
Patent application number | Description | Published |
20080208473 | METHOD FOR CALCULATING ENVIRONMENTAL LOAD, PROGRAM FOR CALCULATING ENVIRONMENTAL LOAD, AND METHOD FOR CONVERTING UNITS - A technology is provided in which it is not necessary to modify a system on a production side, and in which man-hours required for registering an environmental load value on a supplier side are not increased, in cases of an item having a mismatch between units, in a process of adding up the environmental load values of a post-production product. The technology includes generating correction information for calculating the environmental load that is registered by the supplier at design time, and calculating the environmental load value at design time by using the correction information. In cases of calculating the environmental load value of a product actually produced from a designed product, the environmental load value is calculated using the correction information generated at design time. | 08-28-2008 |
20090083333 | DESIGN SUPPORT SYSTEM - The present invention solves the problems with the prior-art environmentally friendly design. That is, in order to achieve continual improvement, it is necessary to make a detailed evaluation based on the parts configuration. If a method of setting a basic unit for each individual part is used, a large number of process steps are required, and it is impossible to conduct accurate life cycle assessments (LCAs) frequently. The present invention provides an environmental impact assessment support and design support system incorporating a database in which information about the basic unit is associated with information about product classifications, parts classifications, and materials classifications. The system manages the information about the parts configuration and the basic unit while associating their histories of creation with each other. | 03-26-2009 |
20090112665 | EXECUTION DECISION SUPPORT PROGRAM AND DEVICE OF REGULATION MEASURES - The present invention calculates a predicted accumulative import amount for each chemical substance for each month by using information on a predicted monthly shipping amount and the amount of a chemical substance contained in the product and specifies the chemical substance whose predicted accumulative import amount exceeds a regulation threshold and the time when the import amount exceeds the regulation threshold. The present invention specifies the product containing the chemical substance, calculates the predicted shipping amount of the product from the threshold excess time of the chemical substance to the end of the year, and calculates the loss amount caused by the loss of sales opportunities from the profit per unit sales amount for each product when any regulation measures are not executed on the chemical substance. The present invention finally calculates the ratio of the expense necessary for the measures and the summed value, and displays the ratio. | 04-30-2009 |
Patent application number | Description | Published |
20120196385 | ASSAY METHOD AND KIT FOR ASSAY EMPLOYING SENSOR CHIP FOR FLUORESCENT MEASURING APPARATUS UTILIZING SURFACE PLASMON-FIELD ENHANCED FLUORESCENCE SPECTROMETRY - An assay method with use of a sensor chip which includes a metal member, a self-assembled monolayer (SAM), and ligands on a support, and is configured to be used for a fluorescence measuring apparatus with utilization of a surface plasmon-field enhanced Fluorescence Spectrometry, including the steps of: forming a hydrophilic high molecule layer on the self-assembled monolayer in the sensor chip; immobilizing the ligands at least one of in the hydrophilic high molecule layer and on the surface of the hydrophilic high molecule layer; and bringing a moisturizer in contact with the hydrophilic high molecule layer. | 08-02-2012 |
20140349278 | NANOHOLE SENSOR CHIP WITH REFERENCE SECTIONS - A device and method for detecting and assessing the quantity of a biological, biochemical, or chemical analyte in a test sample using a simple light source and the naked eye are disclosed. In one embodiment, the device comprises a nanohole sensor chip with two sections, the first of which is a test section, upon which capture agents for a particular analyte are immobilized, and the second of which is a reference section, upon which capture agents conjugated with known quantities of the analyte are immobilized. In another embodiment of the invention, a nanohole sensor chip with a test section and a plurality of reference sections is disclosed. The sensor utilizes light intensity changes exhibited by Fano resonances in the nanoholes for detection of analytes, and allows comparison between the light intensity changes between the reference sections and the test sections for assessing the quantity of the analyte in the sample. | 11-27-2014 |