Patent application number | Description | Published |
20120154582 | SYSTEM AND METHOD FOR PROTOCOL ADHERENCE - The system and method disclosed herein provides an integrated and automated workflow, sensor, and reasoning system that automatically detects breaches in protocols, appropriately alarms and records these breaches, facilitates staff adoption of protocol adherence, and ultimately enables the study of protocols for care comparative effectiveness. The system provides real-time alerts to medical personnel in the actual processes of care, thereby reducing the number of negative patient events and ultimately improving staff behavior with respect to protocol adherence. | 06-21-2012 |
20140188767 | Computer-Implemented Methods and Systems for Determining Fleet Conditions and Operational Management Thereof - A method for determining fleet conditions and operational management thereof, performed by a central system includes receiving fleet data from at least one distributed data repository. The fleet data is substantially representative of information associated with a fleet of physical assets. The method also includes processing the received fleet data for the fleet using at least one process of a plurality of processes. The plurality of processes assess the received fleet data into processed fleet data. The method additionally includes determining a fleet condition status using the processed fleet data and the at least one process of the plurality of processes. The method further includes generating a fleet response. The fleet response is substantially representative of a next operational step for the fleet of physical assets. The method also includes transmitting the fleet response to at least one of a plurality of fleet response recipients. | 07-03-2014 |
20140188768 | System and Method For Creating Customized Model Ensembles On Demand - A computer-implemented system for creating customized model ensembles on demand is provided. An input module is configured to receive a query. A selection module is configured to create a model ensemble by selecting a subset of models from a plurality of models, wherein selecting includes evaluating an aspect of applicability of the models with respect to answering the query. An application module is configured to apply the model ensemble to the query, thereby generating a set of individual results. A combination module is configured to combine the set of individual results into a combined result and output the combined result, wherein combining the set of individual results includes evaluating performance characteristics of the model ensemble relative to the query. | 07-03-2014 |
20140188777 | METHODS AND SYSTEMS FOR IDENTIFYING A PRECURSOR TO A FAILURE OF A COMPONENT IN A PHYSICAL SYSTEM - A computer-implemented system for identifying a precursor to a failure of a particular type of component in a physical system is provided. The physical system includes sensors coupled to the physical system. The computer-implemented system includes a computing device, a database, a processor, and a memory device. The memory device includes historical data including sensor measurements. When instructions are executed by the processor, the processor receives the historical data from the memory device. The processor generates a predictive model. The predictive model uses, as inputs, sensor measurements in the historical data. The predictive model is able to differentiate between sensor measurements taken before the repair event and those taken after the repair event without a time of the repair event being an input to the predictive model. The processor designates at least one sensor measurements used as inputs to the predictive model as precursors to the failure of the component. | 07-03-2014 |
20140189702 | SYSTEM AND METHOD FOR AUTOMATIC MODEL IDENTIFICATION AND CREATION WITH HIGH SCALABILITY - A system includes a library of algorithms, and a request module configured to receive an execution request. The system also includes a job scheduler/optimizer module configured to select algorithms from the library and to create at least one execution job based on the algorithms and the execution request. The system further includes a resource module configured to determine execution computing resources from multiple computing sources, including internal computing resources and external computing resources. The system also includes an executor module configured to transmit an execution job to the computing resources. | 07-03-2014 |
Patent application number | Description | Published |
20130133306 | Starter Control Valve Prediction System to Predict and Trend Starter Control Valve Failures in Gas Turbine Engines Using a Starter Control Valve Health Prognostic, Computer Readable Medium and Related Methods - Starter control valve failure prediction machines, systems, computer readable media, program products, and computer implemented methods to predict and trend starter control valve failures in gas turbine engines using a starter control valve health prognostic and to make predictions of starter control valve failures, are provided. A computer implemented method according to an embodiment of the present invention can include the steps of generating a continuous starter control valve deterioration trend function responsive to a plurality of health indices derived from gas turbine engine startup data downloaded from gas turbine engine sensors for a plurality of startups and analyzing the continuous starter control valve deterioration trend function to identify potential starter control valve failure points where the points on the starter control valve deterioration trend function correlate to a starter control valve health prognostic responsive to historic gas turbine engine startup data downloaded from gas turbine engine sensors. | 05-30-2013 |
20150355901 | METHOD AND SYSTEM TO AUTOMATE THE MAINTENANCE OF DATA-DRIVEN ANALYTIC MODELS - A method, system, and non-transitory computer-readable medium, the method including determining automatically, by a processor, whether behavior for a model representing a plurality of entities and relationships therebetween deviates from a reference behavior for the model; determining, in response to the determination that the model does deviate from the reference behavior, at least one basis for the deviation; automatically forecasting an estimate of a remaining useful life for the model; and modifying the model to compensate for the deviation by at least one of modifying the model to accommodate the deviation and updating the model based on at least one new requirement. | 12-10-2015 |
20150371190 | SYSTEMS AND METHODS FOR PROVISIONING A FLEET OF INDUSTRIAL ASSETS AS A COMPUTING-CLOUD - A system and method for leveraging industrial asset computing capacity into a distributed computing system is disclosed. The method including receiving from a requesting entity a request for available computing capacity, the request including at least one computational task, determining the available computing capacity across a network of interconnected industrial assets, each industrial asset including at least one central controller, allocating at least one of the interconnected industrial assets to perform at least a portion of the computational request, providing the allocated industrial assets with computer executable instructions and data related to performing the computational request, performing at least a portion of the computational request at the allocated industrial assets, obtaining the results of the performing step from the allocated industrial assets; and returning the obtained results to the requesting entity. A system to implement the method and a computer-readable medium are disclosed. | 12-24-2015 |
Patent application number | Description | Published |
20090048876 | SYSTEM AND PROCESS FOR A FUSION CLASSIFICATION FOR INSURANCE UNDERWRITING SUITABLE FOR USE BY AN AUTOMATED SYSTEM - A method and system for fusing a collection of classifiers used for an automated insurance underwriting system and/or its quality assurance is described. Specifically, the outputs of a collection of classifiers are fused. The fusion of the data will typically result in some amount of consensus and some amount of conflict among the classifiers. The consensus will be measured and used to estimate a degree of confidence in the fused decisions. Based on the decision and degree of confidence of the fusion and the decision and degree of confidence of the production decision engine, a comparison module may then be used to identify cases for audit, cases for augmenting the training/test sets for re-tuning production decision engine, cases for review, or may simply trigger a record of its occurrence for tracking purposes. The fusion can compensate for the potential correlation among the classifiers. The reliability of each classifier can be represented by a static or dynamic discounting factor, which will reflect the expected accuracy of the classifier. A static discounting factor is used to represent a prior expectation about the classifier's reliability, e.g., it might be based on the average past accuracy of the model, while a dynamic discounting is used to represent a conditional assessment of the classifier's reliability, e.g., whenever a classifier bases its output on an insufficient number of points it is not reliable. | 02-19-2009 |
20090082919 | METHOD AND SYSTEM FOR EFFICIENT DATA COLLECTION AND STORAGE - A system for collecting and storing performance data for an engine is provided. The system includes one or more sensors configured to generate sensor data signals representative of one or more engine data performance parameters. The system further includes a data sampling component, a data quantizing component, a data storage sampling rate component, a data encoding component and a data storage component. The data sampling component is configured to sample the sensor data signals at a data sampling rate. The data quantizing component is configured to generate quantized data samples corresponding to the sampled sensor data signals. The data storage sampling rate component is configured to determine a data storage sampling rate for the quantized data samples, based on an analysis of at least a subset of the quantized data samples. The data encoding component is configured to encode the quantized data samples according to the data storage sampling rate, and the data storage component is configured to store the encoded data samples from the encoding component. | 03-26-2009 |
20090287512 | System And Process For Dominance Classification For Insurance Underwriting Suitable For Use By An Automated System - A risk classification technique that exploits the existing risk structure of the decision problem in order to produce risk categorizations for new candidates is described. The technique makes use of a set of candidates for which risk categories have already been assigned (in the case of insurance underwriting, for example, this would pertain to the premium class assigned to an application). Using this set of labeled candidates, the technique produces two subsets for each risk category: the Pareto-best subset and the Pareto-worst subset by using Dominance. These two subsets can be seen as representing the least risky and the most risky candidates within a given risk category. If there are a sufficient number of candidates in these two subsets, then the candidates in these two subsets can be seen as samples from the two hypothetical risk surfaces in the feature space that bound the risk category from above and below respectively. A new candidate is assigned a risk category by verifying if the candidate lies within these two bounding risk surfaces. | 11-19-2009 |
20110040470 | Starter Control Valve Failure Prediction Machine To Predict and Trend Starter Control Valve Failures In Gas Turbine Engines Using A Starter Control Valve Health Prognostic, Program Product and Related Methods - Starter control valve failure prediction machines, systems, program products, and computer implemented methods to predict and trend starter control valve failures in gas turbine engines using a starter control valve health prognostic and to make predictions of starter control valve failures, are provided. A computer implemented method according to an embodiment of the present invention can include the steps of generating a continuous starter control valve deterioration trend function responsive to a plurality of health indices derived from gas turbine engine startup data downloaded from gas turbine engine sensors for a plurality of startups and analyzing the continuous starter control valve deterioration trend function to identify potential starter control valve failure points where the points on the starter control valve deterioration trend function correlate to a starter control valve health prognostic responsive to historic gas turbine engine startup data downloaded from gas turbine engine sensors. | 02-17-2011 |
Patent application number | Description | Published |
20100041875 | MODIFIED GP140 ENVELOPE POLYPEPTIDES OF HIV-1 ISOLATES, COMPOSITIONS, STABILIZED TRIMERIC COPLEXES, AND USES THEREOF - This invention provides a modified gp140 envelope polypeptide of an HIV-1 isolate comprising a gp120 polypeptide portion comprising consecutive amino acids and a gp41 ectodomain polypeptide portion comprising consecutive amino acids, said gp41 ectodomain polypeptide portion being modified to comprise isoleucine (I) at an amino acid position equivalent to amino acid position 535; glutamine (Q) at an amino acid position equivalent to amino acid position 543; serine (S) at an amino acid position equivalent to amino acid position 553; lysine (K) at an amino acid position equivalent to amino acid position 567; and arginine (R) at an amino acid position equivalent to amino acid position 588, the amino acid positions being numbered by reference to the HIV-1 isolate KNH1144. This invention also provides nucleic acids encoding such a polypeptide, vectors, host cells, trimeric complexes and compositions thereof. Also provided are antibodies generated against the modified polypeptides and trimeric complexes, and methods of using the modified polypeptides, compositions and trimeric complexes. | 02-18-2010 |
20110076298 | Soluble stabilized trimeric hiv env proteins and uses thereof - This invention provides a protein comprising (a) a first polypeptide which comprises consecutive amino acids, the sequence of which corresponds to the sequence of a modified gp120 envelope polypeptide portion of a gp140 envelope of (i) an HIV-I KNH1144 isolate, or a quasi-species thereof, or (ii) an HIV-I 5768.4 isolate, or a quasi-species thereof; and (b) a second polypeptide which comprises consecutive amino acids, the sequence of which corresponds to the sequence of a modified gp41 ectodomain polypeptide portion of the gp140 envelope of (i) the HIV-I KNH1144 isolate or such quasi-species thereof, or (ii) the HIV-I 5768.4 isolate or such quasi-species thereof. This invention also provides nucleic acids encoding such proteins, vectors, host cells and compositions thereof. Also provided are trimeric complexes (‘trimers’) of these proteins and methods of using such trimers to combat HIV-I infection. | 03-31-2011 |
20110250220 | MODIFIED GP140 ENVELOPE POLYPEPTIDES OF HIV-1 ISOLATES, COMPOSITIONS, STABILIZED TRIMERIC COMPLEXES, AND USES THEREOF - This invention provides a modified gp140 envelope polypeptide of an HIV-1 isolate comprising a gp120 polypeptide portion comprising consecutive amino acids and a gp41 ectodomain polypeptide portion comprising consecutive amino acids, said gp41 ectodomain polypeptide portion being modified to comprise isoleucine (I) at an amino acid position equivalent to amino acid position 535; glutamine (Q) at an amino acid position equivalent to amino acid position 543; serine (S) at an amino acid position equivalent to amino acid position 553; lysine (K) at an amino acid position equivalent to amino acid position 567; and arginine (R) at an amino acid position equivalent to amino acid position 588, the amino acid positions being numbered by reference to the HIV-1 isolate KNH1144. This invention also provides nucleic acids encoding such a polypeptide, vectors, host cells, trimeric complexes and compositions thereof. Also provided are antibodies generated against the modified polypeptides and trimeric complexes, and methods of using the modified polypeptides, compositions and trimeric complexes. | 10-13-2011 |
Patent application number | Description | Published |
20110319976 | DEVICE AND METHOD FOR PREVENTING STENOSIS AT AN ANASTOMOSIS SITE - The present invention relates to treating or preventing stenosis at an anastomosis site. In one embodiment, the present invention is a stent is curved along the longitudinal axis for placement in and adjacent to the graft orifice. In a further embodiment, the stent is drug coated to allow delivery of antivasculoproliferative drugs directly to the vicinity of the graft orifice. In a further embodiment, the stent is expandable by use of an external wire. In another embodiment, the present invention is a kit comprising the specially configured stent together with a sleeve comprising a biocompatible matrix material and a pharmaceutical agent, wherein the sleeve is applied to the external surface of the vessel or graft, resulting in extravascular delivery of a pharmaceutical agent. Methods for treating or preventing stenosis at an anastomosis site by applying the extravascular sleeve and the intravascular stent are also provided. | 12-29-2011 |
20140065198 | Medical Implants and Methods for Regulating the Tissue Response to Vascular Closure Devices - Devices and methods for reducing, eliminating, preventing, suppressing, or treating tissue responses to hemostatic devices e.g., biological sealants or vascular procedures are disclosed. The invention employs a combination of resorbable, biocompatible matrix materials and a variety of therapeutic agents, such as antiproliferatives or antibiotics, applied to a vascular puncture or incision to achieve hemostasis following diagnostic or interventional vascular catheterizations and to treat neointimal hyperplasia and stenosis. A matrix of a material such as collagen provides a reservoir of a therapeutic agent such as rapamycin (sirolimus) and its derivatives and analogs for delivery at a tissue site at risk for vasculoproliferation, infection, inflammation, fibrosis or other tissue responses. | 03-06-2014 |
20140088681 | DEVICE AND METHOD FOR PREVENTING STENOSIS AT AN ANASTOMOSIS SITE - The present invention relates to treating or preventing stenosis at an anastomosis site. In one embodiment, the present invention is a stent is curved along the longitudinal axis for placement in and adjacent to the graft orifice. In a further embodiment, the stent is drug coated to allow delivery of antivasculoproliferative drugs directly to the vicinity of the graft orifice. In a further embodiment, the stent is expandable by use of an external wire. In another embodiment, the present invention is a kit comprising the specially configured stent together with a sleeve comprising a biocompatible matrix material and a pharmaceutical agent, wherein the sleeve is applied to the external surface of the vessel or graft, resulting in extravascular delivery of a pharmaceutical agent. Methods for treating or preventing stenosis at an anastomosis site by applying the extravascular sleeve and the intravascular stent are also provided. | 03-27-2014 |
20150335793 | Medical Implants and Methods for Regulating the Tissue Response to Vascular Closure Devices - Devices and methods for reducing, eliminating, preventing, suppressing, or treating tissue responses to hemostatic devices e.g., biological sealants or vascular procedures are disclosed. The invention employs a combination of resorbable, biocompatible matrix materials and a variety of therapeutic agents, such as antiproliferatives or antibiotics, applied to a vascular puncture or incision to achieve hemostasis following diagnostic or interventional vascular catheterizations and to treat neointimal hyperplasia and stenosis. A matrix of a material such as collagen provides a reservoir of a therapeutic agent such as rapamycin (sirolimus) and its derivatives and analogs for delivery at a tissue site at risk for vasculoproliferation, infection, inflammation, fibrosis or other tissue responses. | 11-26-2015 |
Patent application number | Description | Published |
20100218472 | Ceramic Structures And Methods Of Making Ceramic Structures - A method of firing a green structure to produce a ceramic structure may comprise heating a firing environment during a first stage of firing of a green structure over a first timed temperature cycle having an average ramp rate sufficient to substantially complete burnout of organic material prior to initiation of clay dehydration proximate a core of the ceramic structure. The method may further comprise heating the firing environment during a second stage of the firing over a second timed temperature cycle having an average ramp rate that is faster than the average ramp rate of the first timed temperature cycle. | 09-02-2010 |
20110129640 | METHOD AND BINDER FOR POROUS ARTICLES - A method for making porous articles, including: depositing a powder mixture layer comprising a binder powder, and at least one structural powder; contacting the powder mixture layer and an aqueous liquid to selectively activate the binder powder and form a green layer; repeating the depositing and the contacting sequence at least one time; and de-powdering and drying of the resulting green body. The binder powder can include, for example, a protein that is soluble in water at or below about 25° C. The disclosure also provides articles, having high porosity and optionally intricate 3D structures, as defined herein. | 06-02-2011 |
20130307176 | Single-Fire Two-Step Soak Method - A method for making a cordierite filter article, including:
| 11-21-2013 |
20140138882 | METHOD OF FIRING CORDIERITE BODIES - Methods of firing a cordierite green body to form a fired cordierite body. The green body comprises cordierite-forming raw materials and organic material, the body having a core portion and a skin portion. The green body is pre-heated to a pre-heat temperature that is less than a thermal decomposition temperature of the organic material. The green body is maintained at the pre-heat temperature for a period of time sufficient to minimize a temperature differential between the core portion and the skin portion. The green body is heated to a low firing temperature in a firing atmosphere sufficient to reduce a content of the organic material and to substantially remove chemically bound water from hydrous alumina. The green body is heated to a high firing temperature in a firing atmosphere sufficient to reduce the content of the organic material prior to a substantial removal of chemically bound water from clay. | 05-22-2014 |
20140252695 | FAST FIRING METHOD FOR CERAMICS - A method for firing a green honeycomb ceramic body in a kiln may include heating the green honeycomb ceramic body in four stages. The first stage may include heating the green honeycomb ceramic body from room temperature to a first temperature that at a first heating rate that is greater than or equal to about 75° C./hr. The second stage may include heating the green honeycomb ceramic body from the first temperature to a second temperature at a second heating rate that is less than or equal to the first heating rate. The third stage may include heating the green honeycomb ceramic body from the second temperature to a hold temperature at a third heating rate that is less than or equal to the first heating rate. The fourth stage may include holding the green honeycomb ceramic body at the hold temperature to remove residual carbon. | 09-11-2014 |
20150028527 | FAST FIRING METHOD FOR HIGH POROSITY CERAMICS - A method for firing a green honeycomb ceramic body including heating the green honeycomb ceramic body from room temperature to a first temperature of about 300° C. The green honeycomb ceramic body is then heated from the first temperature to a second temperature of greater than or equal to about 800° C. at a heating rate of greater than or equal to about 90° C./hr. The green honeycomb ceramic body may have a diameter of from greater than or equal to about 4.0 inches to less than or equal to about 9.0 inches, and it may include a carbon-based pore former in a concentration of from greater than or equal to about 10% to less than or equal to about 45% by weight. | 01-29-2015 |