Patent application number | Description | Published |
20090082569 | NARCISTATIN PRODRUGS - The present invention provides prodrugs derived from the sparingly soluble anticancer isocarbostyril narciclasine, a component of various | 03-26-2009 |
20090131672 | SYNTHESIS OF SODIUM NARCISTATIN AND RELATED COMPOUNDS - The present invention involves use of the compounds narciclasine (2a) and 7-deoxy-narciclasine (2c), which are obtained via isolation from the medicinal plant species | 05-21-2009 |
20090221666 | STILBENE DERIVATIVES AND METHODS OF INHIBITING CANCER CELL GROWTH AND MICROBIAL GROWTH - The present invention provides stilbene derived compounds having antineoplastic and/or antimicrobial activity. Preferred compounds of the invention include compounds of the formula (I) wherein R is Dap, Dap-Dil, Dap-Dil-Val, or Dap-Dil-Val-Dov; R | 09-03-2009 |
20090298784 | ISOLATION AND STRUCTURE OF TURBOSTATINS 1-4 - Described herein are novel cerebroside compounds, designated as Turbostatin 1, Turbostatin 2, Turbostatin 3, and Turbostatin 4. These compounds were extracted and isolated from the marine mollusk Turbo stenogyrus, and their structures elucidated. The new compounds exhibit significant cancer cell growth inhibition activity against a variety of murine and human cancer cell lines, and as such appear will be useful in the treatment of various forms of neoplastic disease. | 12-03-2009 |
20100179108 | Synthesis of Sodium Narcistatin and Related Compounds - The present invention involves use of the compounds narciclasine (2a) and 7-deoxy-narciclasine (2c), which are obtained via isolation from the medicinal plant species | 07-15-2010 |
20100197570 | Cyclodepsipeptides with Antineoplastic Activity and Methods of Using to Inhibit Cancer and Microbial Growth - The present invention is directed to cyclodepsipeptide compounds having antineoplastic and/or antimicrobial activity, preferably Kitastatin 1. The present invention is further directed to methods of inhibiting cancer cell growth and/or microbial growth in a host inflicted therewith by administering cyclodepsipeptide compounds to the inflicted host. | 08-05-2010 |
20130184201 | Cyclodepsipeptides with Antineoplastic Activity and Methods of Using to Inhibit Cancer and Microbial Growth - The present invention is directed to cyclodepsipeptide compounds having antineoplastic and/or antimicrobial activity, preferably Kitastatin 1. The present invention is further directed to methods of inhibiting cancer cell growth and/or microbial growth in a host inflicted therewith by administering cyclodepsipeptide compounds to the inflicted host. | 07-18-2013 |
20140023666 | AURISTATIN TYRAMINE PHOSPHATE SALTS AND AURISTATIN AMINOQUINOLINE DERIVATIVES AND PRODRUGS THEREOF - The present invention relates to new auristatin compounds and prodrugs thereof, compositions comprising them and uses thereof. | 01-23-2014 |
20140179897 | CRYSTAL STRUCTURES OF DOLASTATIN 16, DOLAMETHYLLEUINE AND DOLAPHENVALINE, AND METHODS FOR PREPARING DOLAMETHYLLEUINE AND DOLAPHENVALINE - The present invention relates to the crystal structures of dolastatin 16, dolamethylleuine and dolaphenvaline. The present invention also relates to processes for preparing dolamethylleuine and dolaphenvaline. The present invention further relates to computer readable medium with crystal structural data and/or information stored thereon. | 06-26-2014 |
20150344522 | AURISTATIN TYRAMINE PHOSPHATE SALTS AND AURISTATIN AMINOQUINOLINE DERIVATIVES AND PRODRUGS THEREOF - The present invention relates to new auristatin compounds and prodrugs thereof, compositions comprising them and uses thereof. | 12-03-2015 |