Patent application number | Description | Published |
20100113486 | USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS - A method of treating a movement abnormality associated with the pathology of a neurological movement disorder, such as Parkinson's disease or Restless Leg(s) Syndrome by administering a therapeutically effective amount of a PDE7 inhibitory agent. An aspect of the invention provides for the administration of a PDE& inhibitory agent in conjunction with a dopamine agonist or precursor, such as levodopa. In another aspect of the invention, the PDE7 inhibitory agent may be selective for PDE7 relative to other molecular targets (i) known to be involved with the pathology of Parkinson's disease or (ii) at which other drug(s) that are therapeutically effective to treat Parkinson's disease act. | 05-06-2010 |
20110091388 | USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS - A method of treating a movement abnormality associated with the pathology of a neurological movement disorder, such as Parkinson's disease or Restless Leg(s) Syndrome by administering a therapeutically effective amount of a PDE7 inhibitory agent. An aspect of the invention provides for the administration of a PDE& inhibitory agent in conjunction with a dopamine agonist or precursor, such as levodopa. In another aspect of the invention, the PDE7 inhibitory agent may be selective for PDE7 relative to other molecular targets (i) known to be involved with the pathology of Parkinson's disease or (ii) at which other drug(s) that are therapeutically effective to treat Parkinson's disease act. | 04-21-2011 |
20110185439 | G PROTEIN COUPLED RECEPTORS AND USES THEREOF - The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels. | 07-28-2011 |
20130247233 | G PROTEIN COUPLED RECEPTORS AND USES THEREOF - The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels. | 09-19-2013 |
20140179717 | Use of PDE7 Inhibitors for the Treatment of Movement Disorders - A method of treating a movement abnormality associated with the pathology of a neurological movement disorder, such as Parkinson's disease or Restless Leg(s) Syndrome by administering a therapeutically effective amount of a PDE7 inhibitory agent. An aspect of the invention provides for the administration of a PDE& inhibitory agent in conjunction with a dopamine agonist or precursor, such as levodopa. In another aspect of the invention, the PDE7 inhibitory agent may be selective for PDE7 relative to other molecular targets (i) known to be involved with the pathology of Parkinson's disease or (ii) at which other drug(s) that are therapeutically effective to treat Parkinson's disease act. | 06-26-2014 |
Patent application number | Description | Published |
20080260744 | G PROTEIN COUPLED RECEPTORS AND USES THEREOF - The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels. | 10-23-2008 |
20090178153 | G PROTEIN COUPLED RECEPTORS AND USES THEREOF - The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels. | 07-09-2009 |
20110214189 | G PROTEIN COUPLED RECEPTORS AND USES THEREOF - The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels. | 09-01-2011 |
Patent application number | Description | Published |
20080301045 | SYSTEM AND METHOD FOR FACILITATING ENGAGEMENT AND COMMUNICATION BETWEEN A COMPANY AND A RECRUITING FIRM - A system to facilitate engagement and communication between a company with an available position and at least one recruiter includes a server coupled to a computer network, a user interface for co-workers at the company coupled to the server over the computer network and a plurality of co-workers post information to the server about an available position of the company, including a bounty, receive information from the server about candidates for the available position of the company, and select a candidate on the server for the available position, and a user interface for recruiters coupled to the server over the computer network and a plurality of recruiters receive information from the server about an available position of the company and submit information to the server about a candidate for the position of the company. | 12-04-2008 |
20090125379 | METHOD TO FACILITATE ENGAGEMENT AND COMMUNICATION BETWEEN A COMPANY AND A RECRUITER INCLUDING A BOUNTY - The present invention includes a method to facilitate engagement and communication between a company with an available position and a recruiter. The method includes the steps of posting information about the available position for the company, and receiving information about a candidate for the available position of the company from the recruiter, and submitting the information about the candidate for the available position of the company to the company. The method further includes the step of receiving payment from the company and transmitting a portion of the payment to the recruiter upon the selection by the company of a candidate for the available position. | 05-14-2009 |
20090125443 | METHOD TO FACILITATE ENGAGEMENT AND COMMUNICATION BETWEEN A COMPANY AND A RECRUITER - The present invention includes a method to facilitate engagement and communication between a company with an available position and a recruiter. The method includes the steps of posting information about the available position for the company, and receiving information about a candidate for the available position of the company from the recruiter, and submitting the information about the candidate for the available position of the company to the company. The method further includes the step of receiving payment from the company and transmitting a portion of the payment to the recruiter upon the selection by the company of a candidate for the available position. | 05-14-2009 |
20130110735 | METHOD TO FACILITATE ENGAGEMENT AND COMMUNICATION BETWEEN A COMPANY AND A RECRUITER INCLUDING A BOUNTY | 05-02-2013 |
Patent application number | Description | Published |
20100101175 | LOCKING CONCRETE INSERT - A locking insert is described for use in a poured concrete structure. The locking insert includes a hollow elongated body, a longitudinal channel with two configured side edges and a channel floor, a paired gear nut and locking plate that interengages said configured side edges, an attachment bolt, and a method to prevent concrete from seeping into the locking insert. The embedment of the locking insert into a concrete structure provides a positive locking, positional and anti-slip method of attachment for a structural or secondary element. The locking insert allows for vertical positioning and locking of the paired gear nut and locking plate to ensure a proper connection with a structural or secondary element through an attachment bolt. The locking insert with an attached outwardly projecting element transfers the load associated with the structural or secondary element throughout the concrete structure to allow for a high strength connection. | 04-29-2010 |
20140174013 | HIGH-STRENGTH RIBBON LOOP ANCHORS AND ANCHORING SYSTEMS UTILIZING THE SAME - A high-strength ribbon loop anchor and cavity wall anchoring system employing the same is disclosed. The ribbon loop anchor is a wire formative construct that is cold-worked with the resultant body having substantially semicircular edges and flat surfaces therebetween. The edges are aligned to receive compressive forces transmitted from the facing wall. The ribbon loops hereof, when part of the anchoring system, interengage with the veneer tie and are dimensioned to preclude significant movement lateral with or normal to the inner wythe. | 06-26-2014 |
20140237934 | Laser Configured Hook Column Anchors and Anchoring Systems Utilizing the Same - A high-strength laser configured column anchor and anchoring system is disclosed. The high-strength column anchor provides high-strength pullout resistance when embedded within the wall bed joint. Specially-configured apertures, edging and dimension restrictions provide for flow-through mortar embedment within the wall bed joint. The edging provides irregular and regular patterns ensuring a secure fit within the bed joint. The column anchors include a hook attachment portion for secure attachment to the column flanges and optionally include a securement bar or clamp to further secure the column anchor to the column flanges. | 08-28-2014 |
20140250814 | LASER CONFIGURED COLUMN ANCHORS AND ANCHORING SYSTEMS UTILIZING THE SAME - A high-strength laser configured column anchor and anchoring system is disclosed. The high-strength column anchor provides high-strength pullout resistance when embedded within the wall bed joint. Specially-configured apertures, edging and dimension restrictions provide for flow-through mortar embedment within the wall bed joint. The edging provides irregular and regular patterns ensuring a secure fit within the bed joint. The column anchors include a flat and rotated form for secure attachment to the column flanges and optionally include a securement bar or clamp to further secure the column anchor to the column flanges. | 09-11-2014 |
20150059280 | ANCHORING SYSTEM HAVING HIGH-STRENGTH RIBBON LOOP ANCHOR - A high-strength ribbon loop anchor and cavity wall anchoring system employing the same is disclosed. The ribbon loop anchor is a wire formative construct that is cold-worked with the resultant body having substantially semicircular edges and flat surfaces therebetween. The edges are aligned to receive compressive forces transmitted from the facing wall. The ribbon loops hereof, when part of the anchoring system, interengage with the veneer tie and are dimensioned to preclude significant movement lateral with or normal to the inner wythe. | 03-05-2015 |
20150089897 | Laser Configured Hook Column Anchors and Anchoring Systems Utilizing the Same - A high-strength laser configured column anchor and anchoring system is disclosed. The high-strength column anchor provides high-strength pullout resistance when embedded within the wall bed joint. Specially-configured apertures, edging and dimension restrictions provide for flow-through mortar embedment within the wall bed joint. The edging provides irregular and regular patterns ensuring a secure fit within the bed joint. The column anchors include a hook attachment portion for secure attachment to the column flanges and optionally include a securement bar or clamp to further secure the column anchor to the column flanges. | 04-02-2015 |
Patent application number | Description | Published |
20160135516 | Athletic Band with Removable Module - A band includes a tubular body configured to be worn on a user's body and a pocket supported by the tubular body, where the pocket defines a cavity and has an access opening providing access to the cavity, and where the pocket is configured to removably receive an electronic module in the cavity through the access opening. An input device is connected to the tubular body and has a port exposed to the cavity of the band, where the port is configured for removable connection to a connector of the electronic module when the electronic module is received in the cavity. The input device may include a button configured to receive user input and a wireless transmitter to transmit a signal to an external device based on the user input. The input device may also include a haptic feedback mechanism for communicating haptic signals to the user. | 05-19-2016 |
20160135695 | Athletic Band with Removable Module - A device for monitoring athletic activity of a user. In one example, the device has a sensor, and executes a calibration process using data received from the sensor to determine a correct positioning of the device on the user. | 05-19-2016 |
20160135696 | Athletic Band with Removable Module - Methods of detecting and reducing error of athletic sensor readouts are disclosed. Methods relate to receiving properties, such as an athlete's body mass index and a physiological property, such as heart rate. Based on a body mass index or other parameter being outside a range, selecting a protocol, such as a heart rate measurement protocol. In further embodiments, a heart rate measurement protocol may be augmented. | 05-19-2016 |
20160135742 | Athletic Band with Removable Module - A band includes a tubular body defining a central passage, where the tubular body is configured to be worn on a user's body such that a portion of the user's body is received in the central passage, and a housing formed of a polymer material and connected to the tubular body. The housing defines a cavity and an access opening providing access to the cavity, and the housing is configured to removably receive an electronic module in the cavity through the access opening. The housing further includes a slot in communication with the cavity, with the slot configured to permit passage of moisture away from the housing. The sides of the tubular body may also define a slope that is from 0-0.75. | 05-19-2016 |
20160135743 | Athletic Band with Removable Module - A performance monitoring system includes an athletic band or other article of apparel worn by a user, with a pocket supported by the article and defining a cavity, where the pocket has a sensor opening extending through an inner wall of the pocket and an access opening providing access to the cavity. The system also includes an electronic module received in the cavity such that the module can be inserted and removed from the cavity through the access opening. The module has a projection on an underside of the electronic module and a sensor mounted on the projection, where the projection extends through the sensor opening when the electronic module is received in the cavity and is configured to place the sensor in close proximity to skin of the user, such that the sensor is configured to sense a physiological parameter of the user. | 05-19-2016 |
20160136882 | Athletic Band with Removable Module - A manufacturing method uses a main body piece formed of an elastic fabric material and having a first portion having a first end, a second portion having a second end opposite the first end, and two side ends extending between the first and second ends. A bonding material is placed in contact with the first and/or second portions, arranged in lines extending in a direction between the first and second ends. The lines are spaced from each other in a second direction extending between the side ends. The main body piece is folded so that the first portion confronts the second portion, defining a fold line, where the bonding material is positioned between the first and second portions. The folded main body piece is then heat pressed and bent so the side ends are connected together to form a band having a tubular body defining a central passage. | 05-19-2016 |