Patent application number | Description | Published |
20130346521 | METHODS AND SYSTEMS FOR PRIORITY-BASED NOTIFICATIONS FOR MOBILE DEVICES - A method comprising of receiving, by a user system that includes at least a processor system having at least one processor and a memory system, a first push notification associated with a first priority level for display on the user system; receiving, by the user system, a second push notification associated with a second priority level for display on the user system, the second priority level being higher than the first priority level; and displaying, by the user system, the second push notification prior to the first push notification based on the first and second priority level. | 12-26-2013 |
20150026165 | FACILITATING MANAGEMENT OF USER QUERIES AND DYNAMIC FILTRATION OF RESPONSES BASED ON GROUP FILTERS IN AN ON-DEMAND SERVICES ENVIRONMENT - In accordance with embodiments, there are provided mechanisms and methods for facilitating management of user queries and dynamic filtration of responses based on group filters in an on-demand services environment in a multi-tenant environment according to one embodiment. In one embodiment and by way of example, a method includes receiving, at a first computing device, a query via an application programming interface (“API”) of a software application at a second computing device, where the query includes one or more filter parameters including a size filter parameter. The method may further include evaluating the query based on the one or more filter parameters including the size filter parameter, selecting a first response based on the size filter parameter, and communicating the first response to be viewed via the API at the second computing device. | 01-22-2015 |
20160105383 | ACTION LINKS - The technology disclosed includes a method for initiating a web service through an action item within a post in a social media network. A request is received from a user for a post to a social network. The request includes a definition for an action-link-group, which comprises one or more action links. The post is created to include the action-link-group and is then uploaded to the network. Upon receiving a selection of an action link within the action-link-group, an action item associated with the action link is performed. | 04-14-2016 |
Patent application number | Description | Published |
20110044352 | TECHNIQUE FOR DETERMINING A POINT-TO-MULTIPOINT TREE LINKING A ROOT NODE TO A PLURALITY OF LEAF NODES - A method is provided for determining a point-to-multipoint tree connecting a root node to a plurality of leaf nodes (some nodes in different domains) used by a path calculation entity associated with a current domain. The method comprises receiving from at least one other path calculation entity associated with a downstream domain at least one message including a first set of identifiers including at least one identifier of a bunch of branches comprising at least one branch and a respective cost associated with said bunch, the bunch comprising at least one branch enabling connection to leaf nodes in downstream domains, and determining at least one new bunch of branches comprising at least one branch as a function of said at least one first set received, said new bunch of branches having a minimum cost and making it possible also to contact the leaf nodes of the current domain. | 02-24-2011 |
20110069609 | TECHNIQUE FOR PROTECTING A POINT-TO-MULTIPOINT PRIMARY TREE IN A CONNECTED MODE COMMUNICATIONS NETWORK - The invention relates to a technique for protecting a point-to-multipoint primary tree in a connected mode communications network set up from a primary root node to leaf nodes in the event of a fault affecting the primary root node by means of a back-up tree between a back-up root node and at least one merge node, said at least one merge node belonging to a branch of the primary tree coming from the primary root node. A merge node executes the following steps:
| 03-24-2011 |
20110173492 | TECHNIQUE FOR PROTECTING LEAF NODES OF A POINT-TO-MULTIPOINT TREE IN A COMMUNICATIONS NETWORK IN CONNECTED MODE - A technique protects, in a communications network, a point-to-multipoint primary tree between a root node and primary leaf nodes of the network if a failure occurs affecting one of the primary leaf nodes. One network node receives from another upstream network node a request to protect the primary tree via a backup branch leading to a backup leaf node situated downstream from said node, if a failure affecting one of the primary leaf nodes to be protected occurs, the backup leaf node being associated with the primary leaf node to be protected. If the node is connected directly to the downstream primary leaf node to be protected, it configures a backup routing rule for routing packets from an upstream primary branch to the downstream backup branch and, possibly, to the downstream primary branch(es) and is activated in the event of a failure affecting the primary leaf node to be protected. | 07-14-2011 |
Patent application number | Description | Published |
20100103785 | TABLE-DRIVEN POWER UTILIZATION METRICS - An apparatus and method for determining the power consumption of one or more disk arrays are described. Power consumption information for various hardware components of the array, especially that for the disk drives since these consume more than 90% of the required power, are stored in a static data table in a database which may be controller firmware. Through inspection of this table and the chosen state of the individual disk drives as directed by a controller, one may determine the power use of the array. | 04-29-2010 |
20100153620 | Storage system snapshot assisted by SSD technology - A method and apparatus for taking a snapshot of a storage system employing a solid state disk (SSD). A plurality of mapping tables in the SSD store data needed to create a one or more point in time snapshots and a current view of the SSD. In response to a write command, the SSD executes its normal write process and updates its mapping tables to indicate the current view of the SSD and additionally retains the original data in a table of pointers to the original data, as the snapshot of an earlier state of the SSD. In the preferred embodiment, the innate ability of SSDs to write data to a new location is used to perform a point-in-time copy with little or no loss in performance in performing the snapshot. | 06-17-2010 |
20100318711 | SIMULTANEOUS INTERMEDIATE PROXY DIRECT MEMORY ACCESS - Disclosed is a method that simultaneously transfers DMA data from a peripheral device to a hardware assist function and processor memory. A first DMA transfer is configured to transfer data from the peripheral to a peripheral DMA engine. While receiving the data, the DMA engine simultaneously transfers this data to processor memory. The DMA engine also transfers a copy of the data to a hardware assist function. The DMA engine may also simultaneously transfer data from processor memory to a peripheral device while transferring a copy to a hardware assist function. | 12-16-2010 |
20110083992 | METHOD AND SYSTEM FOR PROVIDING A CUSTOMIZED STORAGE CONTAINER - A method and system for providing a customized storage container includes a generally rectangular housing and at least one printed circuit board contained within the rectangular housing. The customized storage container encloses a first row of interconnector modules that are positioned adjacent to a first, open end of the rectangular housing. The customized storage container also encloses a second row of interconnector modules positioned adjacent to the first, open end of the rectangular housing. At least one air vent is positioned along a side of the rectangular housing and adjacent to a second, closed end of the rectangular housing. According to one exemplary embodiment, the storage container can comprise a single printed circuit board for supporting the first and second row of interconnector modules. In another exemplary embodiment, the storage container can comprise two printed circuit boards for supporting the first and second rows interconnector modules. | 04-14-2011 |
20110185099 | Modular and Redundant Data-Storage Controller And a Method for Providing a Hot-Swappable and Field-Serviceable Data-Storage Controller - A modular and redundant storage controller system includes management modules, controller modules and an interconnect module. The management modules provide direct-current power and signals to respective controller modules. The controller modules include respective signal interfaces, direct-current interfaces, and interconnect interfaces. The signal interfaces couple the controllers to a respective management module. The direct-current interfaces couple the controllers to a respective management module. The interconnect module includes a pair of connectors arranged to couple a pair of the controller modules via the respective interconnect module interfaces. | 07-28-2011 |
20110231674 | INDEPENDENT DRIVE POWER CONTROL - Disclosed is a storage system enclosure. A midplane receives, from a controller coupled to the midplane, a first drive status signal and a second drive status signal. The first drive status signal and the second drive status signal are associated with a storage device. The first drive status signal indicates a fault condition associated with the storage device. The second drive status signal indicates that an action is allowed on the storage device. A drive power control supplies or removes power from the storage device in response to the state of the first drive status signal and the second drive status signal. | 09-22-2011 |
20110238938 | EFFICIENT MIRRORING OF DATA ACROSS STORAGE CONTROLLERS - A method includes multicasting an Input/Output (I/O) data associated with a host computing device through a multicast device associated with a storage controller coupled to another storage controller in a redundant configuration, and minoring, through the multicasting, the I/O data across the storage controller and the another storage controller through a bus utilized to couple the storage controller and the another storage controller. The method also includes transmitting an early write status message to the host computing device following the minoring of the I/O data across the storage controller and the another storage controller. The early write status message is associated with a successful completion of the mirroring of the I/O data across the storage controller and the another storage controller prior to the I/O data being written to a storage device associated therewith. | 09-29-2011 |
20150058533 | DATA STORAGE CONTROLLER AND METHOD FOR EXPOSING INFORMATION STORED IN A DATA STORAGE CONTROLLER TO A HOST SYSTEM - A data storage controller exposes information stored in a locally managed volatile memory store to a host system. The locally managed volatile memory store is mapped to a corresponding portion of a peripheral component interconnect express (PCIe) compliant memory space managed by the host system. Backup logic in the data storage controller responds to a power event detected at the interface between the data storage controller and the host system by copying the contents of the volatile memory store to a non-volatile memory store on the data storage controller. Restore logic restores a data storage controller state by copying the contents of the non-volatile memory store to the locally managed volatile memory store upon the application of power such that the data in the volatile memory store is persistent even in the event of a loss of power to the host system and or the data storage controller. | 02-26-2015 |
Patent application number | Description | Published |
20120087515 | CIRCUIT, SYSTEM AND METHOD FOR ISOLATING A TRANSDUCER FROM AN AMPLIFIER IN AN ELECTRONIC DEVICE - A circuit, device and method for controlling an output signal of an amplifier are provided. The output signal may be controlled through a first stage located before a digital to analog converter and/or a second stage located after it. The first stage boosts the digital signal to match with the full signal range of the converter. For the second stage, the circuit comprises: a first resistor coupled to an output of the amplifier in series, the first resistor having a resistance value Rs; a second resistor coupled to the first resistor in series, the second resistor having a resistance value Rp; and an output terminal for a transducer connected to the electronic device, the output terminal connected in parallel to the second resistor. In the circuit, the resistance values Rs and Rp are related by an inversely proportional relationship. The circuit provides an output signal at the output terminal having a noise floor that varies with an output level of the amplifier and a constant output impedance as seen from the transducer. | 04-12-2012 |
20120177229 | PRINTED CIRCUIT BOARD WITH AN ACOUSTIC CHANNEL FOR A MICROPHONE - A printed circuit board with an acoustic channel for a microphone and a portable electronic device having such a printed circuit board are provided. In accordance with one embodiment, there is provided a microphone assembly, comprising: a printed circuit board (PCB) comprising a board body having at least one signal trace, the printed circuit board defining an acoustic channel within the board body which extends between a microphone aperture in the board body and a plurality of inlet openings in the board body. | 07-12-2012 |
20120237044 | Electronic Device and Audio Accessory Having a Plurality of Passive Switches for Controlling the Audio Device - According to some aspects, a system for controlling an electronic device including an audio accessory coupled to the electronic device. The audio accessory has at least one speaker adapted to provide audio output and a plurality of resistive switches. The electronic device has a bias voltage source adapted to provide power to the resistive switches via a bias resistor and a ground connection, and a measurement module. The measurement module is adapted to monitor a bias point to determine which of the at least one switch has been engaged based on effect of the resistive switches on the ground offset voltage after compensating for a ground offset voltage caused by the audio output. | 09-20-2012 |
20120327048 | MOBILE COMPUTING DEVICES - A mobile computing device includes a flexible display, a rigid-flex printed circuit board (PCB) arrangement, an electrically conductive memory fabric, and a controller. The rigid-flex PCB arrangement is connected to the flexible display, and has a honeycomb configuration. The electrically conductive memory fabric is connected to the flexible display and the rigid-flex PCB arrangement. The controller is configured to, by selectively controlling supply of electrical current to the electrically conductive memory fabric, control whether the electrically conductive memory fabric (i) straightens and resists flexing of the flexible display and the rigid-flex PCB arrangement or (ii) is relaxed and allows flexing of the flexible display and the rigid-flex PCB arrangement. | 12-27-2012 |
20130065428 | ELECTRONIC DEVICE AND METHOD OF DETECTING A PROPER CABLE CONNECTION - An electronic device, systems and methods are described for detecting whether there has been a proper cable connection when a plug is inserted into a socket. A pressure sensor configured to measure air pressure within the socket generates one or more pressure signals as a function of the air pressure, and a processor determines whether a proper cable connection has been made (whether the plug has been fully inserted into the socket) as a function of the pressure signals. | 03-14-2013 |
20130094668 | PROXIMITY SENSING FOR USER DETECTION AND AUTOMATIC VOLUME REGULATION WITH SENSOR INTERRUPTION OVERRIDE - A mobile device includes at least one speaker and an audio subsystem for providing an audio signal to the at least one speaker for playback by the at least one speaker. The audio subsystem operates by detecting a distance to a user of the mobile device using a proximity sensor and controlling volume output of the at least one speaker based on the distance to the user of the mobile device and the operational status of the proximity sensor. If it is determined that the proximity sensor is functional, the audio subsystem applies a gain factor to the audio signal that varies based on the distance to the user or limits the maximum allowable speaker output based on the distance. A high or low gain setting may be applied for when the user is far away or in close proximity to the mobile device. | 04-18-2013 |
20130108068 | HEADSET WITH TWO-WAY MULTIPLEXED COMMUNICATION | 05-02-2013 |
Patent application number | Description | Published |
20100215183 | AUDIO JACK FOR A PORTABLE ELECTRONIC DEVICE - A portable electronic device includes a processor provided in a housing, a jack being sized for receiving a plug of an audio accessory and having electrical connectors for enabling communication between the audio accessory and the processor, the electrical connectors for contacting corresponding electrical connectors of the plug and a switching circuit in communication with the processor and the electrical connectors, the switching circuit for determining a pin-out of the plug and routing audio signals between ungrounded ones of the corresponding electrical connectors of the plug and the processor. | 08-26-2010 |
20120142225 | AUDIO JACK FOR A PORTABLE ELECTRONIC DEVICE - A portable electronic device having an audio jack is provided. The device comprises: a processor; a jack for receiving a plug of an audio accessory; electrical connectors provided in the jack for enabling communication between the audio accessory and the processor and for contacting corresponding electrical connectors of the plug; and a switching circuit in communication with the processor and two of the electrical connectors. The switching circuit routes audio signals between the corresponding electrical connectors and the processor; after insertion of the plug into the jack, conducts a test on the electrical connectors to determine if a first one of the corresponding electrical connectors is electrically grounded. A method for routing the signals is also provided. | 06-07-2012 |
20120144072 | AUDIO JACK CONFIGURATOR FOR A PORTABLE ELECTRONIC DEVICE - A portable electronic device having an audio jack is provided. The device comprises: a processor provided in a housing; a display screen; a jack provided in the housing, the jack being sized for receiving a plug of an audio accessory of the plurality of audio accessories; electrical connectors provided in the jack for enabling communication between the audio accessory and the processor, each of the electrical connectors for contacting a corresponding electrical connector of the plug; and a switching circuit in communication with the processor and two of the electrical connectors. For the device, upon detection of insertion of the plug into the jack, the processor is adapted to generate a prompt on the display screen to allow selection of a pin-out configuration for the audio accessory from different pin-out options for the audio accessory. A method of configuring audio jacks for an electronic device is also provided. | 06-07-2012 |
Patent application number | Description | Published |
20120302222 | METHODS AND APPARATUS TO ASSOCIATE A MOBILE DEVICE WITH A PANELIST PROFILE - Methods and apparatus are disclosed to associate a mobile device with a panelist profile. An example method includes initializing a metering application on the mobile device to operate with partial functionality, parsing a message log with the metering application to identify an installation message, extracting a telephone number from the installation message and saving to a memory of the mobile device, sending an initialization message based on the extracted telephone number to prompt an authorization message, and enabling full functionality of the metering application in response to receiving the authorization message. | 11-29-2012 |
20130072150 | METHODS AND APPARATUS TO ASSOCIATE A MOBILE DEVICE WITH A PANELIST PROFILE - Methods and apparatus are disclosed to associate a mobile device with a panelist profile. An example method includes initializing a metering application on the mobile device to operate with partial functionality, parsing a message log with the metering application to identify an installation message, extracting a telephone number from the installation message and saving to a memory of the mobile device, sending an initialization message based on the extracted telephone number to prompt an authorization message, and enabling full functionality of the metering application in response to receiving the authorization message. | 03-21-2013 |
20140106703 | METHODS AND APPARATUS TO ASSOCIATE A MOBILE DEVICE WITH A PANELIST PROFILE - Methods and apparatus are disclosed to associate a mobile device with a panelist profile. An example method includes initializing a metering application on the mobile device to operate with partial functionality, parsing a message log with the metering application to identify an installation message, extracting a telephone number from the installation message and saving to a memory of the mobile device, sending an initialization message based on the extracted telephone number to prompt an authorization message, and enabling full functionality of the metering application in response to receiving the authorization message. | 04-17-2014 |
Patent application number | Description | Published |
20120086367 | ACTUATING DEVICE, MICROSYSTEM DEVICE, AND METHOD FOR CONTROLLING A MICROMECHANICAL ACTUATOR - A method, actuating device, and microsystem device are described for controlling a micromechanical actuator, which has a rechargeable capacitor for generating a mechanical motion of the micromechanical actuator, a memory having a lookup table containing previously computed data of signal shapes for controlling the micromechanical actuator, and a driver circuit having a driver circuit control unit for processing the previously computed data, a power stage for generating the signal shapes, and an output for outputting the signal shapes, corresponding to previously computed data, to the micromechanical actuator's rechargeable capacitor. The micromechanical actuator has a limiting device, between the output of the driver circuit and the micromechanical actuator, which is for limiting a voltage excursion of the signal shapes output by the driver circuit, which are usable for generating the mechanical motion by recharging the micromechanical actuator's rechargeable capacitor. The micromechanical actuator's power consumption is reducible by limiting the voltage excursion. | 04-12-2012 |
20120262775 | Micro-Mirror System And Associated Control Method - A micro-mirror system having a micro-mirror actuator, a sensor for detecting the position of the micro-mirror actuator, a light module having at least one light source and an associated control system via which a light intensity of the light source is controllable, and an evaluation and control unit which is designed to control the micro-mirror actuator as a function of an output signal of the sensor. The system provides that the evaluation and control unit includes a compensation routine in which an offset voltage of the output signal of the sensor is settable as a function of the light intensity of the light source to be expected at the point in time that the micro-mirror actuator is activated. | 10-18-2012 |
20130293161 | DIGITAL CONTROL FOR A MICROELECTROMECHANICAL ELEMENT - A control circuit for a microelectromechanical element includes: a waveform generator, which is designed to generate a digital trigger signal for the microelectromechanical element, a modulator, which is designed to oversample the digital trigger signal, to subject the signal to a noise shaping, and to output the oversampled and noise-shaped digital trigger signal; and a digital driver device, which is designed to drive the microelectromechanical element using the oversampled and noise-shaped digital trigger signal. | 11-07-2013 |
20140117888 | MECHANICAL COMPONENT, MECHANICAL SYSTEM, AND METHOD FOR OPERATING A MECHANICAL COMPONENT - A mechanical component has: a mount; an adjustable part selectively set at least into a first vibration mode having a first natural frequency and into a second vibration mode having a second natural frequency; a first sensor unit providing a first sensor signal; and a second sensor unit providing a second sensor signal. The first and second sensor units are interconnected in such a way that an overall signal is generated with the aid of at least the first and second sensor signals, the overall signal having an overall ratio of a first maximum absolute value which arises in the event of an excitation of the first vibration mode, and a second maximum absolute value which arises in the event of an excitation of the second vibration mode. | 05-01-2014 |
20140118005 | MECHANICAL COMPONENT AND MANUFACTURING METHOD FOR A MECHANICAL COMPONENT - A mechanical component has: a mounting; a movable part which, with the aid of at least one first spring and one second spring, is connected to the mounting in such a way that the movable part is movable about a rotational axis extending through a first anchoring area of the first spring on the mounting and a second anchoring area of the second spring on the mounting; a first sensor device with at least one first resistor which is situated on and/or in the first spring; and a second sensor device with at least one second resistor situated on and/or in the second spring. The first sensor device includes a first Wheatstone half bridge and the second sensor device includes a second Wheatstone half bridge. The first and second Wheatstone half bridges are connected to form a Wheatstone full bridge. | 05-01-2014 |
20140232643 | LASER PROJECTION DEVICE AND METHOD - A laser projection device is described having a projection unit, which is designed to project an image and to generate an interrupt signal as a function of a distance of the projection unit from at least one object located in front of the projection unit in the projection direction, and having an application control unit, which is designed to control the projection unit as a function of the interrupt signal. A method is also described. | 08-21-2014 |
Patent application number | Description | Published |
20150062681 | METHOD FOR ADAPTING THE PARAMETERS OF A CONTROLLER FOR MICROMECHANICAL ACTUATORS, AND DEVICE - A method for adapting the parameters of a controller for micromechanical actuators, including the following steps: acting on the micromechanical actuator with a test signal which has a step, detecting a test signal response of the micromechanical actuator to the test signal, identifying an absolute position of at least one mode in the detected test signal response, and adapting at least one of the parameters of the controller based on the identified absolute position of the at least one mode. Moreover, a corresponding device is described. | 03-05-2015 |
20150062684 | CONTROLLER FOR ACTUATING A MICROMECHANICAL ACTUATOR, ACTUATING SYSTEM FOR ACTUATING A MICROMECHANICAL ACTUATOR, MICRO-MIRROR SYSTEM AND METHOD FOR ACTUATING A MICROMECHANICAL ACTUATOR - A controller for actuating a micromechanical actuator, including a first signal input which is designed to receive a reference signal, a second signal input which is designed to receive a measuring signal which denotes a recorded response by the micromechanical actuator to a control signal, a first controller element which is designed to filter and/or to attenuate predefined frequency modes and/or predefined frequency components in the received reference signal and to output a filtered and/or attenuated reference signal, a second controller element which is designed to modify the received measuring signal in order to minimize the quality of the first mode of the received measuring signal and to output a modified measuring signal, a third controller element which is designed to minimize the deviation between the filtered and/or attenuated reference signal and the received measuring signal and to output a minimized reference signal, a fourth controller element which is designed to modify the bandwidth of the received measuring signal and to subtract it from the minimized reference signal, which makes up the control signal. Furthermore, a corresponding actuating system, a corresponding micro-mirror system and a corresponding method are described. | 03-05-2015 |
20150066161 | Controller for actuating a micromechanical actuator, actuating system for actuating a micromechanical actuator, micro-mirror system and method for actuating a micromechanical actuator - A controller for a micromechanical actuator, and corresponding actuating system, micro-mirror system and method, including a first input for a reference signal, a second input for a measuring signal denoting a recorded response to a control signal, a first controller element to filter/attenuate predefined frequency modes and/or predefined frequency components in the received reference signal and to output a filtered/attenuated reference signal, a second controller element to modify the received measuring signal to minimize the quality of the first/further modes by processing the received measuring signal and to output a modified measuring signal, a third controller element to minimize deviation between the filtered/attenuated reference and received measuring signals and to output a minimized reference signal, a fourth controller element to rotate the phase of the difference between the minimized reference and modified measuring signals for at least one predefined frequency and to transmit the modified reference as the control signal. | 03-05-2015 |
20150163451 | DEVICE FOR PROJECTING AN IMAGE, PORTABLE MOBILE DEVICE COMPRISING A CORRESPONDING DEVICE, AND A METHOD FOR PROJECTING AN IMAGE - A device for projecting an image includes: a video signal device designed to provide a video signal that has a first image refresh rate; a mirror control device designed to control a micro-mirror device with a second image refresh rate adapted to at least one characteristic of the micro-mirror device and to the first image refresh rate; and a projection device designed to project the video signal provided by the video signal device with the first image refresh rate, using the micro-mirror device moved by the second image refresh rate. | 06-11-2015 |
Patent application number | Description | Published |
20080293639 | PEPTIDES AND PEPTIDE MIMETICS TO TREAT PATHOLOGIES CHARACTERIZED BY AN INFLAMMATORY RESPONSE - This invention provides novel active agents (e.g. peptides, small organic molecules, amino acid pairs, etc.) peptides that ameliorate one or more symptoms of atherosclerosis and/or other pathologies characterized by an inflammatory response. In certain embodiment, the peptides resemble a G* amphipathic helix of apolipoprotein J. The agents are highly stable and readily administered via an oral route. | 11-27-2008 |
20090163408 | SALICYLANILIDES ENHANCE ORAL DELIVERY OF THERAPEUTIC PEPTIDES - This invention pertains to the surprising discovery that salicylanilides, e.g., niclosamide and/or niclosamide analogues when orally administered in conjunction with a peptide pharmaceutical (e.g., a class A amphipathic helical peptide as described herein) significantly increases the bioavailability of that peptide. Methods of peptide delivery using such “delivery agents” and pharmaceutical formulations are provided. | 06-25-2009 |
20100227825 | PEPTIDES AND PEPTIDE MIMETICS TO TREAT CANCER - This invention provides novel active agents (e.g. peptides, small organic molecules, amino acid pairs, etc.) peptides that ameliorate one or more symptoms of atherosclerosis and/or other pathologies characterized by an inflammatory response. In certain embodiment, the peptides resemble a G* amphipathic helix of apolipoprotein J. The agents are highly stable and readily administered via an oral route. | 09-09-2010 |
20100240598 | PEPTIDES AND PEPTIDE MIMETICS TO INHIBIT THE ONSET AND/OR PROGRESSION OF FIBROTIC AND/OR PRE-FIBROTIC PATHOLOGIES - This invention provides methods of inhibiting the onset or progression of a fibrotic disease (or pre-fibrotic pathology) in a mammal. The method involves administering oen or more peptides (e.g., class A amphipathic helical peptides, G* peptides, etc.) as described herein to a mammal in need thereof, in an amount effective to inhibit the onset and/or progression of the fibrotic disease (or pre-fibrotic condition) in the mammal. In certain embodiments the fibrotic disease is selected from the group consisting of retroperitoneal fibrosis (RPF), hepatic fibrosis and/or chirrhosis, renal fibrosis, and pancreatic fibrosis | 09-23-2010 |
20110183889 | SALICYLANILIDE MODIFIED PEPTIDES FOR USE AS ORAL THERAPEUTICS - This invention pertains to the surprising discovery that salicylanilides, e.g., niclosamide and/or niclosamide analogues can be reacted with a therapeutically active peptide to produce a modified peptide complex that shows increased resistance to proteolysis and that shows higher bioactivity when orally administered than the unmodified peptide. | 07-28-2011 |
20120004720 | G-TYPE PEPTIDES AND OTHER AGENTS TO AMELIORATE ATHEROSCLEROSIS AND OTHER PATHOLOGIES - This invention provides novel peptides, and other agents, that ameliorate one or more symptoms of atherosclerosis and/or other pathologies characterized by an inflammatory response. In certain embodiment, the peptides resemble a G* amphipathic helix of apolipoprotein J. The peptides are highly stable and readily administered via an oral route. | 01-05-2012 |
20120035095 | ORALLY ADMINISTERED PEPTIDES SYNERGIZE STATIN ACTIVITY - This invention provides novel peptides that ameliorate one or more symptoms of atherosclerosis. The peptides are highly stable and readily administered via an oral route. The peptides are effective to stimulate the formation and cycling of pre-beta high density lipoprotein-like particles and/or to promote lipid transport and detoxification. This invention also provides a method of tracking a peptide in a mammal. In addition, the peptides inhibit osteoporosis. When administered with a statin, the peptides enhance the activity of the statin permitting the statin to be used at significantly lower dosages and/or cause the statins to be significantly more anti-inflammatory at any given dose. | 02-09-2012 |
20130295042 | Peptides and Peptide Mimetics to Treat Pathologies Associated With Eye Disease - This invention provides novel active agents (e.g. peptides, small organic molecules, amino acid pairs, etc.) peptides that ameliorate one or more symptoms of eye disease and/or other pathologies characterized by an inflammatory response. In certain embodiment, the peptides resemble a G* amphipathic helix of apolipoprotein J. The agents are highly stable and readily administered via an oral route or via intraocular injection. | 11-07-2013 |
20130344173 | MODULATING DISEASE THROUGH GENETIC ENGINEERING OF PLANTS - In certain embodiments transgenic plants (e.g., transgenic tomatoes) are provided that comprise cells that express a peptide one or more domains of which comprise the amino acid sequence of an apolipoprotein or apolipoprotein mimetic peptide where the peptide has biological activity (e.g., lowers SAA, and/or increases paroxonase activity, and/or improves HDL inflammatory index, etc.) when the plant and/or the peptide is fed to a mammal. | 12-26-2013 |
Patent application number | Description | Published |
20080213816 | Mitochondrial enoyl coenzyme a hydratase 1 as marker for diagnosing stomach cancer - The present invention relates to mitochondrial protein that can be used as a marker for diagnosing stomach cancer. According to the present invention, the marker for diagnosing stomach cancer comprises mitochondrial enoyl coenzyme A hydratase 1. | 09-04-2008 |
20110269136 | BIOMARKER AND COMPOSITION FOR DIAGNOSIS OF PREECLAMPSIA AND METHOD FOR USING THE SAME - The present invention relates to a biomarker and a composition for diagnosis of preeclampsia. In accordance with one aspect of the present invention, there is provided a biomarker for diagnosis of preeclampsia using an enzyme selected from the group consisting of placental chondroitin 4-O-sulfotransferase 1 (C4ST), chondroitin 6-sulfotransferase (C6S), heparan sulfate 6-O-sulfotransferase 1 (HS6S), and dermatan/chondroitin sulfate 2-sulfotransferase (CS-2OST), or uronic acid-2-sulfate (UA2S). | 11-03-2011 |
20120309009 | METHOD FOR THE DIAGNOSIS OF PREECLAMPSIA - The present invention relates to a biomarker and a composition for diagnosis of preeclampsia. In accordance with one aspect of the present invention, there is provided a biomarker for diagnosis of preeclampsia using an enzyme selected from the group consisting of placental chondroitin 4-O-sulfotransferase 1 (C4ST), chondroitin 6-sulfotransferase (C6S), heparan sulfate 6-O-sulfotransferase 1 (HS6S), and dermatan/chondroitin sulfate 2-sulfotransferase (CS-2OST), or uronic acid-2-sulfate (UA2S). | 12-06-2012 |