Patent application number | Description | Published |
20080213743 | Method for adjusting sedimentation rates - One or more chemicals are added to a physiological fluid to alter the density and/or shape of cells in the fluid to provide a desired sedimentation rate of the cells. In a preferred embodiment, the chemical to be added is an anticoagulant, preferably ACD. | 09-04-2008 |
20090120852 | Method and apparatus for separating fluid components - A floating element for separating components of a physiological fluid comprises two parts that are relatively movable. The two parts define a prescribed volume between them when at their maximum separation, and one of the parts may be moved toward the other to express the fluid contained in the volume between the parts. The parts are made of materials having densities so that they assume a desired position in the fluid to allow selected components to be easily obtained and expressed. | 05-14-2009 |
20090131877 | Method and apparatus for separating fluid components - A floating element for separating components of a physiological fluid comprises two parts that are relatively movable. The two parts define a prescribed volume between them when at their maximum separation, and one of the parts may be moved toward the other to express the fluid contained in the volume between the parts. The parts are made of materials having densities so that they assume a desired position in the fluid to allow selected components to be easily obtained and expressed. | 05-21-2009 |
20090283524 | Blood components separator disk - A separator disk for use in centrifugal separation of components is designed to automatically position itself during separation at the interface between the supernatant and the remaining components. Preferably the interface is between plasma and red blood cells. | 11-19-2009 |
20100016830 | Injection of Anticoagulant Into Bone Marrow Space - A method for aspirating bone marrow includes the step of injecting anticoagulant into the area Of the bone marrow cavity surrounding the entry site of the aspiration needle. The amount of anticoagulant may be relatively small because the primary objective is to address the damage caused by entry of the needle into and through regions of the bone marrow cavity. As little as 0.5 ml heparin is injected prior to aspiration. Additional anticoagulant is provided in the collection syringe to facilitate further processing, as by centrifugal fractionation of the marrow to obtain desired components. | 01-21-2010 |
20110036786 | FLOATING DISK FOR SEPARATING BLOOD COMPONENTS - A floating separating element for use in centrifugal separation of components of a physiological fluid comprises a positioning part and a separating part, where the positioning part is designed to automatically assume a position in a supernatant and a separating part is positioned at a desired location with respect to the interface between the supernatant and heavier components. In preferred embodiments the physiological fluids are blood or bone marrow aspirate, and the heavier components comprise red blood cells. The positioning part comprises the majority of the mass of the separating element and is thin so that differences in the position of the separating element with respect to the interface are small compared to differences in the densities of the separated compoments, particularly the component comprising red blood cells. A method allows red blood cells to move the separating element during decanting to ensure complete decant of the supernatant. | 02-17-2011 |
20110160031 | DECANTING CENTRIFUGE WITH VIBRATION ISOLATION - A centrifuge has a rotor for receiving a disposable processing unit. The centrifuge is configured such that the motor is attached to an enclosure and the enclosure is supported on a base. The connection between the base and the enclosure is a vibration isolator, and the isolator is positioned such that its effective line of action aligns with the effective plane of rotation of the rotor. In accordance with another feature of the invention, the processing units are held in a decanting position by a decant ring that moves vertically but does not rotate. The ring engages the top of the processing unit during decant and the abrasion is minimal. | 06-30-2011 |
20110278233 | FLOATING DISK FOR SEPARATING BLOOD COMPONENT - A floating separating element for use in centrifugal separation of components of a physiological fluid comprises a positioning part and a separating part, where the positioning part is designed to automatically assume a position in a supernatant and a separating part is positioned at a desired location with respect to the interface between the supernatant and heavier components. In preferred embodiments the physiological fluids are blood or bone marrow aspirate, and the heavier components comprise red blood cells. The positioning part comprises the majority of the mass of the separating element and is thin so that differences in the position of the separating element with respect to the interface are small compared to differences in the densities of the separated components, particularly the component comprising red blood cells. A method allows red blood cells to move the separating element during decanting to ensure complete decant of the supernatant. | 11-17-2011 |
20110319246 | METHOD AND APPARATUS FOR SEPARATING FLUID COMPONENTS - A floating element for separating components of a physiological fluid comprises two parts that are relatively movable. The two parts define a prescribed volume between them when at their maximum separation, and one of the parts may be moved toward the other to express the fluid contained in the volume between the parts. The parts are made of materials having densities so that they assume a desired position in the fluid to allow selected components to be easily obtained and expressed. | 12-29-2011 |
20130079212 | BLOOD COMPONENTS SEPARATOR DISK - A separator disk for use in centrifugal separation of components is designed to automatically position itself during separation at the interface between the supernatant and the remaining components. Preferably the interface is between plasma and red blood cells. | 03-28-2013 |
20130137564 | FLOATING DISK FOR SEPARATING BLOOD COMPONENTS - A floating separating element for use in centrifugal separation of components of a physiological fluid comprises a positioning part and a separating part, where the positioning part is designed to automatically assume a position in a supernatant and a separating part is positioned at a desired location with respect to the interface between the supernatant and heavier components. In preferred embodiments the physiological fluids are blood or bone marrow aspirate, and the heavier components comprise red blood cells. The positioning part comprises the majority of the mass of the separating element and is thin so that differences in the position of the separating element with respect to the interface are small compared to differences in the densities of the separated components, particularly the component comprising red blood cells. A method allows red blood cells to move the separating element during decanting to ensure complete decant of the supernatant. | 05-30-2013 |
20140131292 | BLOOD COMPONENTS SEPARATOR DISK - A separator disk for use in centrifugal separation of components is designed to automatically position itself during separation at the interface between the supernatant and the remaining components. Preferably the interface is between plasma and red blood cells. | 05-15-2014 |
20140135199 | METHOD AND APPARATUS FOR SEPARATING FLUID COMPONENTS - A floating element for separating components of a physiological fluid comprises two parts that are relatively movable. The two parts define a prescribed volume between them when at their maximum separation, and one of the parts may be moved toward the other to express the fluid contained in the volume between the parts. The parts are made of materials having densities so that they assume a desired position in the fluid to allow selected components to be easily obtained and expressed. | 05-15-2014 |
20140274650 | SEGREGATION OF OILS IN THE FRACTIONATION OF ASPIRATED ADIPOSE TISSUES - Adipose is obtained from aspirated adipose by centrifugal separation of adipose from tumescent fluids and oils released from damaged adipose cells. Aspirated adipose is placed in a container having therein a disk that floats on adipose and takes up the released oils whereby they are unlikely to remix with the adipose during handling after centrifugation. The disk also adheres to the adipose by entraining part of the adipose layer. | 09-18-2014 |
Patent application number | Description | Published |
20130259923 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF SECRETED PROTEINS - The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | 10-03-2013 |
20130259924 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF BIOLOGICS AND PROTEINS ASSOCIATED WITH HUMAN DISEASE - The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | 10-03-2013 |
20140010861 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH HUMAN DISEASE - The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | 01-09-2014 |
20140275227 | COMPOSITIONS AND METHODS OF ALTERING CHOLESTEROL LEVELS - The present invention relates to compositions, methods and kits using polynucleotides, primary transcripts and mmRNA molecules. | 09-18-2014 |
20150064235 | MODIFIED POLYNUCLEOTIDES - The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | 03-05-2015 |
20150064236 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS - The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | 03-05-2015 |
20150086614 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF CYTOPLASMIC AND CYTOSKELETAL PROTEINS - The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | 03-26-2015 |
20150111248 | IN VIVO PRODUCTION OF PROTEINS - The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | 04-23-2015 |
20150246139 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF NUCLEAR PROTEINS - The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | 09-03-2015 |
Patent application number | Description | Published |
20080225485 | Distributed transmit/receive integrated microwave module chip level cooling system - A radar transmit and receive integrated microwave module with conductively cooled condenser side rails and one or more vacuum brazed fluid distribution manifold cold plates in fluid communication with the side rails. There are one or more transmit and receive modules on a cold plate. Each module includes a coolant input and a coolant output. One or more gallium nitride monolithic microwave integrated circuits are within each transmit and receive module and each include a micro heat exchanger in fluid communication with the coolant input and the coolant output of the transmit and receive module to directly cool the gallium nitride monolithic microwave integrated circuit. | 09-18-2008 |
20090185352 | HIGH PERFORMANCE POWER DEVICE - A printed circuit board (PCB) assembly is provided. The PCB assembly is adapted for mounting at least one heat-generating electrical device and providing integrated heat dissipating capability to dissipate heat generated by the electrical device. The PCB assembly has a top surface and a bottom surface and comprises a signal carrying layer and an insert of pyrolytic graphite (PG). The signal carrying layer, disposed between the top surface and the bottom surface, comprises a material that is both thermally conductive and electrically conductive (such as at least one of aluminum, copper, and silver and alloys thereof) and has at least a portion lying in a first plane. The insert of PG is disposed within at least a portion of the first plane of the signal carrying layer, is in thermal contact with the signal carrying layer, and is constructed and arranged to have its greatest electrical conductivity in the first plane. Optionally, a conductive via can be formed in portions of the signal carrying layer not occupied by the insert of PG, where the conductive via operably couples a first side of the signal carrying layer to a second side of the signal carrying layer. | 07-23-2009 |
20100038056 | High performance compact heat exchanger - A high performance compact heat exchanger includes a base plate with evaporator channels for cooling a heat source adjacent to the base plate. A condenser is connected to the base plate and includes fins with channels therein for the coolant. A pump delivers the coolant to the evaporator channels of the base plate after passing through the fins of the condenser. | 02-18-2010 |
20100039770 | Pneumatic presssure wedge - An electronic subsystem such as an array of radar transmit/receive microwave modules are associated with (e.g., base mounted to) spaced heat sinks. There is an electronic module on each side of each heat sink and an inflatable bladder or “pneumatic pressure wedge” between adjacent heat sinks biases a pair of electronic modules against their respective heat sinks. | 02-18-2010 |
20100245179 | Method and Apparatus for Thermal Management of a Radio Frequency System - A thermal management system includes an air duct assembly comprising a supply air duct having an air inlet opening, a return air duct having an air exit opening and a plurality of distribution air ducts configured to be in fluid communication with the air inlet opening of the supply air duct and with the air exit opening of the return air duct. A fan is disposed within the air duct assembly to direct air from the air inlet opening of the supply air duct through the supply air duct and out the air exit opening of the return air duct. The fan and supply duct are disposed to direct air over a first surface of a heat sink. A second opposing surface of the heat sink is disposed over and configured to be in thermal contact with a plurality of active circuits disposed on a first surface of a radio frequency (RF) multi-layer printing wiring board (PWB). | 09-30-2010 |
20120063098 | ASSEMBLY TO PROVIDE THERMAL COOLING - In one aspect, an assembly to provide thermal cooling includes a first member having a first channel configured to receive a cooling fluid, a second member having a second channel configured to receive the cooling fluid and a first plurality of hollow and flexible conduits connecting the first and second members. Each of the first plurality of hollow and flexible conduits is configured to provide a path for the cooling fluid to flow between the first and second channels. | 03-15-2012 |
20120146862 | COOLING ACTIVE CIRCUITS - In one aspect, an assembly includes a panel that includes a first surface. The panel also includes a first active circuit coupled to the first surface of the panel and a cold plate having a first bore. The cold plate includes a first inner surface exposed by the first bore. The panel further includes a first thermally conductive material in contact with the first inner surface of the cold plate and the first active circuit. | 06-14-2012 |
Patent application number | Description | Published |
20100263251 | Front loading frame display arrangement - A thin, graphic support assembly comprising an elongated base rail and an elongated cover rail which come together around a board to form four sides of a frame. A spring mechanism is fully captured after the base rail and cover rail are assembled together, and the angle and position of the spring channel allows the hinge location to be at the top/outer edge of the frame. The elongated base rail and elongated cover rail can be oriented in a parallel relationship when closed for capturing a display panel or a perpendicular relationship when open for inserting or removing a display panel. | 10-21-2010 |
20110252680 | Surface mounted frame arrangement - A four sided frame arrangement for displaying and readily changing a graphic therewithin, comprising three support rails connected to a loading rail, joined by “L” shaped connector brackets at the corners of the frame arrangement, the support rails each having a graphic receiving channel therein for receipt of a graphic slid therein from an adjacent loading rail; wherein the support rails each have a rear flange which defines one side of the graphic receiving channel, wherein the rear flange of the support rails extend widthwise beyond the front leg or edge of the respective support rails and wherein the support and loading rails each have an outer face of generally “C” shape in cross-section. | 10-20-2011 |
20120066949 | Abuttable snap frame graphic display arrangement - An elongated abuttable snap frame arrangement for biasably, removably, capturing a display graphic support and for display thereof, the arrangement comprising: an elongated base panel, an elongated cover that is flexibly attached to the base panel at its upper edge, and an elongated hinge member flexibly attached to the elongated base panel and the elongated cover, the cover able to rotate from a parallel closed position to a generally perpendicular open position without interfering with adjacent objects or other abutting snap frame arrangements. | 03-22-2012 |
20120210622 | Illuminated front loading frame display - A thin, illuminatable graphic support assembly comprising an elongated base rail having an elongated first edge and an elongated second edge; an elongated cover rail having an elongated planar portion arranged along one edge thereof, and an elongated “J” shaped portion arranged along a second edge thereof, the elongated cover rail pivotable between an open orientation and a closed graphic or panel restraining position; an elongated receiving channel arranged in the elongated second edge of the base rail, with a biasing member arranged therein, and a fixture support first channel and a fixture support second channel on an outer lower side of the base rail, to enable the illuminable graphic support assembly to be selectively secured to a wall. | 08-23-2012 |
20150107142 | Illuminable double-sided frame arrangement - A multi-component frame assembly for the display of at least one illuminable graphic panel. The frame assembly includes a frame made of at least one single frame member and at least one split rail frame member, which are joined together by a plurality of connecting brackets. The split rail frame member is comprised of an elongated first side split rail and an elongated second side split rail separated apart by a mid rail member disposed therebetween. The at least one single frame member has a cross-sectional configuration of “U” shape, and is comprised of an exterior bridge member and an interior bridge member for supporting strips of light emitting diodes. The interior bridge member has a bracket channel on one side of the interior bridge member and a graphic receiving channel on the other side of the interior bridge member to enable receipt of one or more graphic display panels. | 04-23-2015 |
Patent application number | Description | Published |
20100192388 | METALLIZED CUTLERY AND TABLEWARE AND METHOD THEREFOR - A plastic cutlery item molded from a plastic material, such as polystyrene, having a metallic coating that imparts to this cutlery item the appearance of metal cutlery or silverware. In one embodiment the plastic cutlery or tableware items are molded using injection molding techniques, and subjected to a vacuum metallizing process in an individualized non-contiguous manner, where a thin metallic layer is deposited on at least one of their surfaces. The resultant items simulate the appearance of metal cutlery or tableware. In one embodiment of the invention the plastic cutlery or tableware articles are molded from a clear polystyrene resin and are coated with a thin stainless steel layer through vacuum sputtering deposition on only one of the sides. The abrasion resistance of the metallic coating can be enhanced by subjecting the articles to a post-metallizing holding period or by applying a clear protective overcoat. | 08-05-2010 |
20120192435 | METALLIZED CUTLERY AND TABLEWARE AND METHOD THEREFOR - A plastic cutlery item molded from a plastic material, such as polystyrene, having a metallic coating that imparts to this cutlery item the appearance of metal cutlery or silverware. In one embodiment the plastic cutlery or tableware items are molded using injection molding techniques, and subjected to a vacuum metallizing process in an individualized non-contiguous manner, where a thin metallic layer is deposited on at least one of their surfaces. The resultant items simulate the appearance of metal cutlery or tableware. In one embodiment of the invention the plastic cutlery or tableware articles are molded from a clear polystyrene resin and are coated with a thin stainless steel layer through vacuum sputtering deposition on only one of the sides. The abrasion resistance of the metallic coating can be enhanced by subjecting the articles to a post-metallizing holding period or by applying a clear protective overcoat. | 08-02-2012 |
20140106145 | METALLIZED CUTLERY AND TABLEWARE AND METHOD THEREFOR - A tableware item molded from a plastic material, such as polystyrene has a metallic coating applied to at least one surface by a sputtering deposition process. The sputtered coating is suitable for food contact without an overcoat, and imparts the appearance of a metal tableware item. In embodiments, the tableware item is a cup, a plate, a bowl, a tray, a lid, a glass, a champagne flute, a goblet, a napkin ring, a candle holder, or a centerpiece receptacle. The metallic coating can be silver, steel, stainless steel, chromium, aluminum, copper, or gold. In some embodiments, the metallic coating is not applied to all surfaces of the tableware item. In various embodiments, the tableware article is molded from a clear polystyrene resin and coated with a thin stainless steel layer on only one side. The abrasion resistance of the metallic coating can be enhanced by applying a clear protective overcoat. | 04-17-2014 |