Patent application number | Description | Published |
20130089548 | METHOD AND COMPOSITIONS TO INDUCE APOPTOSIS OF TUMORAL CELLS EXPRESSING SHH - A method for inducing apoptosis of tumoral cells in a patient having cancer cells bearing Cell-adhesion molecule-related/Downregulated by Oncogenes (CDO) receptors and expressing Sonic Hedgehog (SHH), including administering to the patient an effective amount of an agonist of CDO's apoptotic function, wherein the agonist is selected from the group consisting of a CDO fragment, a fusion protein comprising a CDO fragment, an antibody against SHH, and an siRNA which is capable of inhibiting SHH expression, and related CDO fragments, fusion proteins comprising a CDO fragment, antibodies against SHH, and siRNAs which are capable of inhibiting SHH expression. | 04-11-2013 |
20130336972 | RECOMBINANT FC-FUSION PROTEIN OF THE FIFTH FIBRONECTIN TYPE III DOMAIN OF DCC - The present invention relates to DCC-fusion proteins, nucleic acid molecules encoding the DCC-fusion proteins, as well as methods for their production and their use in treatment of cancer such as colorectal cancer, NSCLC and metastatic breast cancer. The present invention also relates to methods of treating cancer such as colorectal cancer, NSCLC and metastatic breast cancer by administering DCC-fusion proteins. | 12-19-2013 |
Patent application number | Description | Published |
20110306053 | Amplification System with Spatial Separation - An automated nucleic acid analysis method and analytical system are described comprising separate modules, wherein the air flow of any one of said modules is controlled and wherein at least the air flow between the module for isolation and purification of the analyte and the module for analysis of the analyte are separated. | 12-15-2011 |
20120067801 | Analyzer Assembly Platform - A method for mounting and combination of an analytical apparatus with a platform for mounting such an apparatus comprising at least two units, and a platform on which said apparatus is mounted is disclosed, said platform comprising at least one platform element, and multiple feet for placing the platform elements on a surface. The feet are individually adjustable in height. | 03-22-2012 |
20130043361 | User interaction with automated analytical apparatus - A method of interaction between an automated analytical apparatus for performing an analytical process and a user is disclosed comprising displaying all features necessary for performing the analytical process on a display which is mounted on the apparatus. | 02-21-2013 |
20130323741 | AMPLIFICATION SYSTEM WITH SPATIAL SEPARATION - An automated nucleic acid analysis method and analytical system are described comprising separate modules, wherein the air flow of any one of said modules is controlled and wherein at least the air flow between the module for isolation and purification of the analyte and the module for analysis of the analyte are separated. | 12-05-2013 |
20130323826 | AMPLIFICATION SYSTEM WITH SPATIAL SEPARATION - An automated nucleic acid analysis method and analytical system are described comprising separate modules, wherein the air flow of any one of said modules is controlled and wherein at least the air flow between the module for isolation and purification of the analyte and the module for analysis of the analyte are separated. | 12-05-2013 |
20150069893 | INSTALLATION OF ANALYTICAL APPARATUS - An analytical apparatus to be installed on a substantially horizontal surface of a diagnostic laboratory is presented. The apparatus comprises a bottom side and an upper working side, the bottom side having at least three casters for rolling the apparatus on a surface and at least two feet. The casters have a fixed height and at least one caster is higher than the other casters so that the apparatus is unbalanced when it is rolled on the surface. The at least two feet are individually adjustable in height so that when the height of the feet is adjusted the upper working side is leveled and the apparatus rests on the at least two feet and the higher caster. An analytical system comprising the analytical apparatus and a method of installing the analytical apparatus and the system are also described. | 03-12-2015 |
Patent application number | Description | Published |
20120043994 | CURRENT BALANCING OF PARALLEL CONNECTED SEMICONDUCTOR COMPONENTS - A method and an arrangement are provided for balancing the switching transient behavior of parallel connected power semiconductor components. The method includes providing a switch signal to the parallel connected power semiconductor components for changing the state of the components, forming control signals for each of the parallel connected components from the switch signal, and determining, during the change of state of the power semiconductor component, the voltage induced to an inductance in the main current path of the component in each of the parallel connected components. The method also includes comparing each of the induced voltages with a predetermined threshold voltage, measuring time differences between the time instants at which the induced voltages crosses the threshold voltage, and modifying one or more of the control signals on the basis of the measured time differences in the respective following state change for balancing the switching transient behavior. | 02-23-2012 |
20150155700 | METHOD AND APPARATUS FOR SHORT CIRCUIT PROTECTION OF POWER SEMICONDUCTOR SWITCH - A method and apparatus are provided for a power semiconductor switch. A current through the switch is responsive to a control terminal voltage at a control terminal of the switch, and the control terminal voltage is driven by a driver unit. The method includes measuring or estimating the current based on a bond voltage of the switch, detecting a short circuit by comparing the measured or estimated current to a short circuit current limit, controlling an on-state voltage level of the control terminal voltage based on the comparison to limit the current through the switch during the short circuit, and controlling the control terminal voltage to an off-state voltage level to turn the switch off. The on-state voltage level voltage is controlled by pulse-width modulating the output of the driver unit. A switching frequency of the modulation is at least the cut-off frequency of low-pass characteristics of the control terminal. | 06-04-2015 |
20150162902 | METHOD AND APPARATUS FOR BALANCING CURRENTS - A method and apparatus are provided for balancing currents of two or more parallel-connected power semiconductor switches during an on-state of the switches. A control terminal of each switch is driven by a driver unit. The method includes determining ratios between the currents through the switches. For each switch, the method includes controlling the voltage at the control terminal on the basis of the ratios by controlling a level of a supply voltage of the driver unit of the switch, and after a turn-on commutation transient, modulating the output of the driver unit. The duty cycle of the modulation is controlled to minimize the time required for the transition of the voltage at the control terminal from the one voltage level to another. | 06-11-2015 |