Patent application number | Description | Published |
20080303658 | Hand Washing Compliance Detection System - Systems and methods are provided for monitoring use of hand washing agents to determine compliance with hand hygiene guidelines. A hand washing agent is provided with a detectable, volatile compound, such as odors, which is then rubbed onto a subject's hands using the subject's hand washing technique. After the hand washing event, the subject's hand is then exposed to an detector (such as a badge), which includes a sensor capable of detecting the volatile compound, and an indicator that communicates detection of the volatile compound, indicating use of the hand washing agent and hand hygiene compliance. | 12-11-2008 |
20090005270 | Systems and Methods for Evaluating Enzyme Competency - The present invention provides systems and methods for determining enzymatic competency, which is important in determining whether a patient may suffer an adverse drug reaction, has a disease associated with defects in specific enzymatic function, and/or has an enzyme defect that is likely to cause pathophysiology. As contemplated herein, a parent molecular entity is administered to a patient in whom enzymatic competency is to be determined. A sample of the patient's bodily fluid is exposed to a sensor of the invention to distinguish, detect, and quantify a detectable entity in the bodily fluid. Sensor-acquired data regarding the detectable entity is used to determine enzymatic competency. Preferably, a sample of a patient's exhaled breath is collected and exposed to the sensor of the invention. Types of sensor systems of the invention include, but are not limited to, surface resonance arrays; microelectromechanical sensors (such as microcantilever-based technology); molecularly imprinted polymer sensors; amplifying fluorescent sensor technology; aptamer-based sensor technology; SAW sensors; infrared sensors; fuel cells; chemical reactors; and pH sensitive sensors. | 01-01-2009 |
20100231385 | Hand Washing Compliance Detection System - Systems and methods are provided for monitoring use of hand washing agents to determine compliance with hand hygiene guidelines. A hand washing agent is provided with a detectable, volatile compound, such as odors, which is then rubbed onto a subject's hands using the subject's hand washing technique. After the hand washing event, the subject's hand is then exposed to an detector (such as a badge), which includes a sensor capable of detecting the volatile compound, and an indicator that communicates detection of the volatile compound, indicating use of the hand washing agent and hand hygiene compliance. | 09-16-2010 |
20130276785 | Central Site Photoplethysmography, Medication Administration, And Safety - A monitoring and control system, apparatus and method for safe administration, reduction or cessation of administration of at least on medication, fluid or both, which includes at least one Central Source Site (CSS) Photoplethysmography (PPG) sensor coupled to means for control of delivery of the at least one medication, fluid or both. | 10-24-2013 |
20130296823 | Intelligent Drug and/or Fluid Delivery System to Optimizing Medical Treatment or Therapy Using Pharmacodynamic and/or Pharamacokinetic Data - A pharmacodynamic (PD), pharmacokinetic (PK), or both and PK guided infusion device, system and method optimizes the safety and efficacy of various forms of treatment or therapy (e.g., drug and/or fluid) in a variety of health-care and other settings. | 11-07-2013 |
20140341983 | SMART.TM. SOLID ORAL DOSAGE FORMS - Solid Oral Dosage Forms (SODFs) comprising Self Monitoring and Reporting Therapeutics (SMART™) adherence technology are provided which require no or minimal modification of clinical trial materials (CTMs) or marketed drug while providing tamper resistant (literally foolproof) measurement of adherence that is highly accurate and without altering the chemical, manufacturing, and controls (CMC) of the CTM or marketed drug. | 11-20-2014 |
20160101194 | SMART.RTM. Medication Adherence Formulation, Method, Device and System for Topical, Vaginal or Rectal Routes of Administration - Novel compositions, methods, systems and devices are disclosed which contain markers for definitive medication adherence monitoring for Active Pharmaceutical Ingredients (APIs) delivered topically, vaginally or rectally. This invention is useful in a wide range of contexts, including, but not limited to, clinical trial settings, home use settings, or other settings, where it is necessary to definitively confirm that a given patient has taken or been administered a given medication at the correct time and in the correct dosage via a topical, vaginal or rectal route of delivery. Specific formulations of markers are disclosed for inclusion in compositions for Active Pharmaceutical Ingredient (API) delivery, including but not limited to delivery of microbicidally active compounds such that on topical, vaginal or rectal delivery, said AEM is detected in the breath or an Exhaled Drug Emplacement Marker, EDEM, which is a metabolite of the AEM, is detected in the breath. | 04-14-2016 |
Patent application number | Description | Published |
20100216175 | Condensate Glucose Analyzer - Systems and methods for analyzing glucose present in exhaled breath condensate (EBC). In certain embodiments, electrochemical- or coulometnc-based sensing technologies are used to analyze EBC for the presence and/or concentration of glucose. Based on the detected glucose m EBC, the subject invention provides systems and methods for non-invasive, accurate assessment of blood glucose levels. | 08-26-2010 |
20140294675 | Marker Detection Method And Apparatus To Monitor Drug Compliance - The present invention includes systems and methods for monitoring therapeutic drug concentration in blood by detecting markers, such as odors, upon exhalation by a patient after the drug is taken, wherein such markers result either directly from the drug itself or from an additive combined with the drug. In the case of olfactory markers, the invention preferably utilizes electronic sensor technology, such as the commercial devices referred to as “artificial” or “electronic” noses or tongues, to non-invasively monitor drug levels in blood. The invention further includes a reporting system capable of tracking drug concentrations in blood (remote or proximate locations) and providing the necessary alerts with regarding to ineffective or toxic drug dosages in a patient. | 10-02-2014 |
20140364384 | MEDICATION ADHERENCE MONITORING SYSTEM - The present invention relates to the detection of markers in exhaled breath, wherein the detection of the presence or absence of the marker(s) in exhaled breath is used to assess various clinical data, including patient adherence in taking the medication and patient enzymatic (metabolic) competence in metabolizing the medication. An embodiment of the invention comprises a parent therapeutic agent labeled with a marker, where upon metabolism (e.g., via enzymatic action) of the therapeutic agent, the marker becomes volatile or semi-volatile and is present in the breath. In certain related embodiments, the marker contain a deuterium label, which is also present in the breath upon metabolism of the therapeutic agent. In another embodiment of the invention, the therapeutic agent is associated with a taggant (that may be either labeled or unlabeled with deuterium), which in turn will generate a marker in the breath that is easily measurable. | 12-11-2014 |
Patent application number | Description | Published |
20090171159 | Method and Devices for Minimally Invasive Arthroscopic Procedures - A surgical device is provided, the device having a tubular outer body member with a handle at its proximal end and a flexible distal end segment extending from its distal end. The surgical device also has an operable end extending from the distal end of the flexible distal end segment. The device is configured for selectively causing the flexible end segment to bend to adopt a desired curvature and for selectively rotating the operable end relative to the flexible distal end segment about an axis of the flexible distal end segment. | 07-02-2009 |
20090240266 | Vessel Occlusion Clip and Application Thereof - An occlusion clip for permanently occluding a bodily vessel, such as the vas deferens. The occlusion clip has a first leg, a second leg, joined on their proximal ends by a spring coil. The spring coil provides a biased torsional force to the first leg and the second leg, to force them into a closed position. The first leg and the second leg have on their distal ends a vessel occlusion portion that occludes the targeted vessel when the clip is in a closed position. | 09-24-2009 |
20110009856 | Combination Radio Frequency Device for Electrosurgery - A radio frequency (RF) device for use in electrosurgery is provided. The RF device comprises a flexible support member having an actuator passage extending therethrough and a flexible actuator member at least partially disposed within the actuator passage. An insulator housing is connected on its proximal side to the distal end of the actuator so that when the flexible actuator member is rotated, the insulator housing rotates about a rotation axis through the distal actuator end. The device also comprises at least one electrode extending distally from the insulator housing, the at least one electrode having first and second energy transmitting surfaces configured so that if the first energy transmitting surface is positioned to deliver electrical current with the insulator housing in a first angular orientation, rotation of the insulator housing to a second orientation positions the second energy transmitting for transfer of electrical current. | 01-13-2011 |