Patent application number | Description | Published |
20080213349 | Liposome Complexes Containing Pharmaceutical Agents and Methods - Liposome complexes are provided for site-specific delivery of pharmaceutical agents with improved targeting efficiency. The liposome complexes include a pharmaceutical agent associated with the liposome; a sialic acid-containing molecule associated with the liposome; and optionally a targeting agent attached to the sialic acid-containing molecule. The invention also provides methods of making liposome complexes and their in vivo administration. | 09-04-2008 |
20090061515 | Methods of inhibiting or suppressing cellular proliferation - Methods of inhibiting or suppressing cellular proliferation are disclosed that include delivering at least one antiproliferative agent into or proximate a cell. In certain embodiments, the antiproliferative agent(s) are hydrolysis products of a biodegradable polymer (e.g., a polyketal polymer). | 03-05-2009 |
20090269390 | MEDICAL DEVICES, POLYMERS, COMPOSITIONS, AND METHODS FOR DELIVERING A HALOACETATE - Polymers, compositions, and medical devices useful for delivering (e.g., by local and/or sustained delivery) a haloacetate (e.g., dichoroacetate) to a tissue are disclosed herein. Such methods can be useful for treatment of diseases such as cancer. | 10-29-2009 |
20100137369 | FLOWABLE PHARMACEUTICAL DEPOT - Flowable pharmaceutical depots are described. The flowable pharmaceutical depot includes a polyester, such as a polylactic acid or a poly(trimethylene carbonate) endcapped with a primary alcohol and a pain relieving therapeutic agent, such as a post operative pain relieving therapeutic agent. Method of making and using the same are also described. | 06-03-2010 |
20100240852 | HETEROATOM-CONTAINING POLYMERS AND METATHESIS POLYMERIZATION METHODS FOR MAKING SAME - Heteroatom-containing polymers such as polyketals, and methods of making and using such heteroatom-containing polymers are disclosed herein. The heteroatom-containing polymers can be useful for applications including, for example, medical devices and pharmaceutical compositions. In a preferred embodiment, the heteroatom-containing polymers are polyketals that are biodegradable. | 09-23-2010 |
20100255051 | POLYKETAL POLYMERS, AND METHODS OF MAKING AND USING SAME - Polyketal polymers, and methods of making and using such polyketal polymers are disclosed herein. The polyketal poylmers can be useful for applications including, for example, medical devices and pharmaceutical compositions. In a preferred embodiment, the polyketal polymers are biodegradable. | 10-07-2010 |
20110065809 | Polymerization of Multifunctional Azides, and Polymers Therefrom - Methods for preparing polymers from multifunctional azides and multifunctional azide-reactants are described in the present disclosure. Exemplary multifunctional azide-reactants include multifunctional alkynes and/or multifunctional α-phosphine esters. In certain embodiments, such polymers can be prepared in vivo. Such polymers can be useful in a wide variety of biomedical applications. | 03-17-2011 |
20110082266 | THERAPEUTIC POLYMERS AND METHODS OF GENERATION - The invention describes poly(ortho ester) polymers that include at least one therapeutic compound in the polymer backbone. The therapeutic compound includes at least one phenol residue and an aliphatic alcohol residue or two or more phenolic residues. | 04-07-2011 |
20110082275 | POLY(ORTHOESTER) POLYMERS, AND METHODS OF MAKING AND USING SAME - Poly(orthoester) polymers, and methods of making and using such poly(orthoester) polymers are provided. The poly(orthoester) polymers can be useful for applications including, for example, medical devices and pharmaceutical compositions. In a preferred embodiment, the poly(orthoester) polymers are biodegradable. | 04-07-2011 |
20120149864 | POLY(ORTHOESTER) POLYMERS, AND METHODS OF MAKING AND USING SAME - Poly(orthoester) polymers, and methods of making and using such poly(orthoester) polymers are provided. The poly(orthoester) polymers can be useful for applications including, for example, medical devices and pharmaceutical compositions. In a preferred embodiment, the poly(orthoester) polymers are biodegradable. | 06-14-2012 |