Kane, MA
Bill Kane, Sutton, MA US
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20140309600 | APPARATUSES AND METHODS FOR DETECTING LEAKS IN A NEGATIVE PRESSURE WOUND THERAPY SYSTEM - Leak location devices and methods of using leak location devices that can be used in conjunction with negative pressure wound therapy systems are disclosed. In some embodiments, a leak location device can include a microphone for detecting sound pressure produced by a leak. Detected sound pressure can be compared to a threshold, which can correspond to background or ambient sound pressure. Background or ambient sound pressure can correspond to sound produced by a negative pressure source. The leak detection device can include a display configured to visually depict the detected sound, and a light source which creates a visual depiction of the coverage angle of the microphone. | 10-16-2014 |
Eric Kane, Lynn, MA US
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20080250753 | Apparatus and method for making inflated articles - An apparatus for making inflated containers from a film web having two juxtaposed film plies generally includes (a) a first sealing device for producing a series of transverse seals that bond the film plies together, (b) an inflation assembly for directing gas between the film plies, (c) a second sealing device for producing one or more longitudinal seals that bond the film plies together, the transverse seals and the longitudinal seals intersecting to enclose the gas between the film plies to thereby form one or more inflated containers, and (d) at least one intermediate sealing element for producing one or more intermediate seals within each inflated container, the intermediate seals partitioning the containers into two or more compartments and providing at least one flow passageway between the compartments to allow the compartments to fluidly communicate with one another. | 10-16-2008 |
20100200169 | Machine for inflating and sealing an inflatable web - A machine for inflating and sealing an inflatable web comprising a series of pre-formed flexible containers, each of the pre-formed containers being capable of holding therein a quantity of gas and having an opening for receiving such gas. | 08-12-2010 |
20140014257 | Apparatus and Method for Making Inflated Articles - A sealing device generally includes a rotatable support cylinder having an outer, circumferential surface and a heating element disposed about such surface and secured thereto such that the heating element rotates therewith. The heating element is coiled about the outer surface of the cylinder in the form of an overlapping helical pattern. Juxtaposed film plies may be sealed together by bringing the sealing device into rotational contact with the juxtaposed film plies and heating the heating element to a temperature sufficient to cause the film plies to seal together. | 01-16-2014 |
Eric A. Kane, Lynn, MA US
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20110271640 | Apparatus and Method for Forming Inflated Containers - A device for producing a longitudinal seal between two juxtaposed plies of film that are conveyed along a longitudinal path of travel, the juxtaposed film plies including a series of containers therebetween, wherein the device includes a sealing mechanism that forms a sealing zone in the travel path in which the longitudinal seal is produced, and a pressure mechanism that forms a pressure zone in the travel path in which the juxtaposed film plies are compressed, the pressure zone being positioned between the containers and the sealing zone. | 11-10-2011 |
20120289378 | Exercise Apparatus - Various embodiments of the present invention are directed to a sliding exercise apparatus. In various embodiments, the sliding exercise apparatus includes a sliding unit with a platform, a sliding surface, a motion sensor, and a transmitter. The sliding unit moves in response to pressure applied against the platform, as the sliding surface is adapted to slide along a ground surface in one or more directions. The motion sensor generates activity data based on one or more characteristics of the movement, such as speed, direction, etc. The transmitter sends the activity data to a computing device, which is adapted for processing, storing, and sharing information based on the activity data. | 11-15-2012 |
James Kane, Needham Heights, MA US
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20080230718 | Feedback control system - An optical sensor feedback control device is provided comprising a luminescent sensing film, an optical processor adjacent the sensing film capable of sinusoidally photoexciting the luminescent sensing film and detecting the luminescent emission resulting therefrom, and a control means in communication with the optical processor for control of the magnitude of the photoexcitation, to receive information regarding the luminescent emission resulting therefrom, and generation of an electrical signal for determination of the magnitude and phase shift of the luminescence relative to the photoexcitation. The device of the present invention further has an optical processor positioning means in communication with the control means and the optical processor for adjusting the physical position of the optical processor and/or light source in relation to the sensing film based on data received from the control means. In addition, a method of feedback control of an optical sensor is provided. | 09-25-2008 |
James A. Kane, Needham Heights, MA US
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20080286154 | Multilayered optical sensing patch and retaining plug therefor - A multilayered optical sensing patch, for the measurement of conditions, such as pH, oxygen level, etc, within containers, is provided. The multilayered optical sensing patch of the present invention is comprised of a heat sealable polymer substrate layer, and a polymeric sensing membrane later attached thereto. The polymer sensing membrane layer is formed of a porous polymer support membrane, and an optical sensing composition immobilized on or within the porous polymer substrate membrane. The heat sealable polymer substrate layer is capable of being securely bonded to the inner layer of bioreactor bags, as well as the porous polymer support substrate layer. Further, the porous polymer support membrane layer provides a firm supporting structure for the polymeric sensing layer, thereby protecting the optical sensing composition disposed therein from degradation/damage. | 11-20-2008 |
20080286155 | Multilayered optical sensing patch and retaining plug therefor - A multilayered optical sensing patch, for the measurement of conditions, such as pH, oxygen level, etc, within containers, is provided. The multilayered optical sensing patch of the present invention is comprised of a heat sealable polymer substrate layer, and a polymeric sensing membrane later attached thereto. The polymer sensing membrane layer is formed of a porous polymer support membrane, and an optical sensing composition (comprising a reactive indicator) covalently bonded thereto. The heat sealable polymer substrate layer is capable of being securely bonded to the inner layer of bioreactor bags, as well as the porous polymer support substrate layer. Further, the porous polymer support membrane layer provides a firm supporting structure for the polymeric sensing layer, thereby protecting the optical sensing composition disposed therein from degradation/damage. | 11-20-2008 |
20100032583 | Optical Chemical Sensor Feedback Control System - An optical chemical sensor feedback control system is provided comprised of a luminescent sensing film, an optical processor adjacent the sensing film capable of sinusoidally photoexciting the luminescent sensing film and detecting the luminescent emission resulting therefrom, and a computer control means executing a computer program, in communication with the optical processor. The computer control means is operable to control the magnitude of the photoexcitation of the luminescent sensing film, wherein the computer control means receives data regarding the luminescent emission resulting therefrom, analyzes same, and determines the magnitude and phase shift of the luminescence relative to the photoexcitation. Further, the system herein is operable to determine the status of the sensing film, and adjust the magnitude of photoexcitation thereof based on same. In addition, the system, via the optical processor positioning means, is operable to adjust the physical position of the optical processor and/or light source in relation to the sensing film, based on data received from the computer control means. | 02-11-2010 |
20100178203 | Non-Invasive Colorimetric-Based Infection Detector And Infection Detecting Bandage - A non-invasive, calorimetric infection detector is provided, comprised of a substrate, and one or more indicator compositions disposed upon or incorporated therein. These indicator compositions exhibit a persistent change color when exposed to gaseous oxides of nitrogen and acids formed therefrom, providing a means of detecting NO production in a wound, which has been found to occur at a high level at the onset of infection in a wound. In addition, a bandage is provided, comprised of the detector, as well as a porous portion, and preferably a hydrophobic barrier layer to protect the detector from contamination by water and other fluids draining from the wound. The non-invasive, calorimetric infection detector, and bandage containing same, can be utilized to provide a convenient, easily utilized colorimetric means of detecting the onset of wound infection, thereby enabling caregivers to effectively and timely treat infections. | 07-15-2010 |
20120107179 | MULTILAYERED OPTICAL SENSING PATCH AND RETAINING PLUG THEREFOR - A multilayered optical sensing patch, for the measurement of conditions, such as pH, oxygen level, etc, within containers, is provided. The multilayered optical sensing patch of the present invention is comprised of a heat sealable polymer substrate layer, and a polymeric sensing membrane later attached thereto. The polymer sensing membrane layer is formed of a porous polymer support membrane, and an optical sensing composition (comprising a reactive indicator) covalently bonded thereto. The heat sealable polymer substrate layer is capable of being securely bonded to the inner layer of bioreactor bags, as well as the porous polymer support substrate layer. Further, the porous polymer support membrane layer provides a firm supporting structure for the polymeric sensing layer, thereby protecting the optical sensing composition disposed therein from degradation/damage. | 05-03-2012 |
20130114855 | Methods and Systems for Detection and Identification of Concealed Materials - Methods and systems for efficiently and accurately detecting and identifying concealed materials. The system includes an analysis subsystem configured to process a number of pixelated images, the number of pixelated images obtained by repeatedly illuminating regions with a electromagnetic radiation source from a number of electromagnetic radiation sources, each repetition performed with a different wavelength. The number of pixelated images, after processing, constitute a vector of processed data at each pixel from a number of pixels. At each pixel, the vector of processed data is compared to a predetermined vector corresponding to a predetermined material, presence of the predetermined material being determined by the comparison. | 05-09-2013 |
20130323845 | CARBON DIOXIDE (CO2) SENSOR - A carbon dioxide detector including a sensor component, where the sensor component has a colorimetric indicator salt of a colorimetric pH indicator and a lipophilic phosphonium quaternary cation, a transparent polymer vehicle or a plasticizer not being in a mixture with the colorimetric indicator salt; and a porous memory, a porous polymer membrane in one instance, the colorimetric indicator salt being deposited on a surface of the porous polymer membrane; the colorimetric indicator salt deposited on the porous polymer membrane does not include a transparent polymer vehicle or a plasticizer, and carbon dioxide detection systems using the detector. | 12-05-2013 |
20140270342 | METHODS AND SYSTEMS FOR DETECTION AND IDENTIFICATION OF CONCEALED MATERIALS - Methods and systems for efficiently and accurately detecting and identifying concealed materials. The system includes an analysis subsystem configured to process a number of pixelated images, the number of pixelated images obtained by repeatedly illuminating regions with a electromagnetic radiation source from a number of electromagnetic radiation sources, each repetition performed with a different wavelength. The number of pixelated images, after processing, constitute a vector of processed data at each pixel from a number of pixels. At each pixel, the vector of processed data is compared to a predetermined vector corresponding to a predetermined material, presence of the predetermined material being determined by the comparison. | 09-18-2014 |
Jeffrey Kane, Hudson, MA US
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20090215150 | Sample container and filtration apparatus and method of filtration using the same - A sample container and filtration apparatus is described comprising a sealable sample container and a surface that is configured to interface with a vacuum base. When the surface interfaces with the vacuum base, a portion of the sample container is broached, providing a pathway for the vacuum source to pull the sample therethrough. In exemplary embodiments, the broachable portion of the sample container comprises an actuating valve. The method for using the sample container and filtration apparatus significantly reduces the possibility of contamination of the sample and during the sample testing procedure relative to the conventional devices and procedures, provides more consistent and reliable test results, and significantly reduces the number of preparation and testing steps for the testing procedure. | 08-27-2009 |
Jeffrey Kane, Worcester, MA US
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20130139617 | Sample Container and Filtration Apparatus and Method of Filtration Using Same - A sample container and filtration apparatus includes a sample container portion with an interior volume and a fluid path passing through a bottom wall. The sample container may also include a valve casing connected to and moveable relative to the sample collection portion between a first and second position. A valve secured to and moveable with the valve casing may close the fluid path of the sample collection portion when in a first position and open the fluid path when in a second position. The apparatus may also include a vacuum base coupling portion that is distal to the valve casing, and includes a filter membrane support surface for supporting a filter membrane. | 06-06-2013 |
Jeffrey F. Kane, Hudson, MA US
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20080290040 | Methods and Apparatus for Foam Control in a Vacuum Filtration System - A flow diverter, vacuum control and tilting of the liquid filtering system are used alternatively or in conjunction to reduce foam production in a filtered liquid sample. A liquid filtering system includes an upper sample reservoir, a filter and a lower storage bottle. A vacuum is applied below the sample filter to draw sample liquid through the sample filter into the storage bottle. A flow diverter may be used to direct flow of the filtered liquid sample onto a sidewall of the storage bottle or guide flow to a bottom of the storage bottle. The vacuum may be regulated to reduce foaming. The liquid filtering system may be tilted to direct fluid to the sidewall of the lower storage bottle and reduce foaming. | 11-27-2008 |
20090026126 | Vacuum Base and Related Methods and Apparatus for Vacuum Filtration - Liquid filter assemblies including an upper sample reservoir, a sample filter and a lower storage bottle are supported by a vacuum base. The base has a vacuum inlet port and, for connection to the liquid filter assembly, a vacuum outlet port. A vacuum is provided through the base to below the sample filter to draw sample liquid through the sample filter into the storage bottle. The base may include an auxiliary vacuum outlet port for connection with additional devices. The bases may be connected from one to another through auxiliary vacuum outlets and the vacuum inlets to make a chain of liquid filter assemblies supplied from one vacuum source. Alternatively, one base may include multiple vacuum outlet ports so that it may support and supply vacuum to a plurality of liquid filter assemblies. | 01-29-2009 |
20090026153 | Method and apparatus for filtrate storage handling - A method of removing a filtrate storage bottle from a water bath includes inserting at least two finger underneath a radially protruding lip of a filtrate storage bottle sealing cap and raising the at least two fingers to lift the bottle from the water bath. A side wall portion of the filtrate storage bottle sealing cap is smaller in perimeter than a circle surrounding the radially protruding lip. The cap creates a liquid tight seal with the filtrate storage bottle. | 01-29-2009 |
20090026154 | Methods and Apparatus for Supporting a Vacuum Filtration Device - A portable fixture for supporting a vacuum filtration device includes a cradle portion and a clamping portion. The cradle portion supports the vacuum filtration device. The clamping portion removeably attaches the portable fixture to a support in order to secure and support the filtration device above a workspace. The portable fixture may also provide a vacuum to the filtration device. To that end, the portable fixture may have a vacuum inlet port which may be connected to a vacuum source and a vacuum outlet port that is fluidly connected to the vacuum inlet port. | 01-29-2009 |
20120294781 | Vacuum Base and Related Methods and Apparatus for Vacuum Filtration - Liquid filter assemblies including an upper sample reservoir, a sample filter and a lower storage bottle are supported by a vacuum base. The base has a vacuum inlet port and, for connection to the liquid filter assembly, a vacuum outlet port. A vacuum is provided through the base to below the sample filter to draw sample liquid through the sample filter into the storage bottle. The base may include an auxiliary vacuum outlet port for connection with additional devices. The bases may be connected from one to another through auxiliary vacuum outlets and the vacuum inlets to make a chain of liquid filter assemblies supplied from one vacuum source. Alternatively, one base may include multiple vacuum outlet ports so that it may support and supply vacuum to a plurality of liquid filter assemblies. | 11-22-2012 |
Jeffrey F. Kane, Worcester, MA US
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20120267301 | Method and Apparatus for Filtrate Storage Handling - A method of removing a filtrate storage bottle from a water bath includes inserting at least two finger underneath a radially protruding lip of a filtrate storage bottle sealing cap and raising the at least two fingers to lift the bottle from the water bath. A side wall portion of the filtrate storage bottle sealing cap is smaller in perimeter than a circle surrounding the radially protruding lip. The cap creates a liquid tight seal with the filtrate storage bottle. | 10-25-2012 |
20130030414 | Caps for Cannula Access Devices - An antiseptic cap and packaging for use with a connector are provided. The antiseptic cap includes a material containing an antiseptic solution. Upon application of the cap to the connector, the material compresses thereby releasing the antiseptic solution. Packaging of the antiseptic cap typically includes a cap holder and a lid. A user could remove the cap from the cap holder before applying it to a connector. Alternatively, the cap holder may be used to apply the cap to the connector. | 01-31-2013 |
20130110087 | System and Method for Clearing Medical Tubing | 05-02-2013 |
Jeffrey Francis Kane, Worcester, MA US
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20110308832 | CABLE ENTRY DEVICE FOR WIRING BOXES - Disclosed herein are embodiments of a wiring box. The wiring box can comprise: a cavity formed by walls having an internal surface inside the cavity and an external surface; and a cable entry device disposed through a hole in a first wall of the walls. The cable entry device can comprise: a support element that retains a grommet in the hole, wherein the support element comprises a stop, a grip extending from the stop, and shutters extending from the stop and defining an opening, wherein the opening converges away from the stop, the grip attaches the support element to the first wall, and wherein the grommet comprises a rim, a sidewall extending from the rim and converging toward a diaphragm. | 12-22-2011 |
John Kane, Salem, MA US
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20130131310 | DRUG-LIGAND CONJUGATES, SYNTHESIS THEREOF, AND INTERMEDIATES THERETO - The present invention relates to methods for synthesizing compounds of formula I or pharmaceutically acceptable salts thereof: (I) wherein each of X, Alk, and W are as defined and described herein. | 05-23-2013 |
John Kane, Maynard, MA US
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20110184021 | 2-Acylaminopropoanol-Type Glucosylceramide Synthase Inhibitors - A compound for use in treating polycystic kidney disease is represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. A method of treating polycystic kidney disease in a subject in need thereof comprises administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. Methods of treating in polycystic kidney disease in a subject in need thereof respectively comprise administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. | 07-28-2011 |
20120322786 | 2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS - A compound for use in treating polycystic kidney disease is represented by Structural Formula (I): | 12-20-2012 |
20120322787 | 2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS - A compound is represented by Structural Formula (I): | 12-20-2012 |
John L. Kane, Maynard, MA US
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20110275673 | INHIBITORS OF SPHINGOSINE KINASE 1 - The invention relates to compounds of Formula (I). Compounds of the present invention are inhibitors of sphingosine kinase 3, and are useful in the treatment of various disorders and conditions, such as inflammatory disorders. | 11-10-2011 |
Kathleen Kane, Brookline, MA US
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20090076412 | Apparatus and Methods for Obtaining a Sample of Tissue - Described herein are systems and methods for obtaining a sample of tissue with low power electrosurgical energy. The systems can include an apparatus for obtaining a sample of tissue from a patient having a cannula having a distal opening for receiving the sample of tissue. A wire, located proximate to the distal opening, can delivery energy to ablate tissue such that damage to the tissue sample is minimized. | 03-19-2009 |
20090125012 | DISPOSABLE ELECTRO-SURGICAL COVER ELEMENTS AND ELECTRO-SURGICAL INSTRUMENT - Electro-surgical instrument and attachments for converting a mechanical surgical instrument into an electro-surgical instrument are disclosed for applying electrical current to tissue, such as a blood vessel, to seal or cauterize the tissue. A cover element is slidable over a distal end of a component of a mechanical surgical instrument, such as a forceps. Each cover element defines a single pocket or cavity and a single aperture or opening at one end thereof for receiving and surrounding the distal end of the component and an electrically conductive element attached to an outer surface of the cover element. RF energy can be applied to tissue through the electrically conductive elements. After the procedure, the cover elements can be slidably removed from the forceps member and are disposable. | 05-14-2009 |
20090125026 | APPARATUS SYSTEM AND METHOD FOR COAGULATING AND CUTTING TISSUE - A combination tissue coagulation and cutting apparatus, system and method for coagulating and cutting tissue. A clamp element includes first and second clamp members having respective first and second porous electrodes, such as sintered metal electrodes. A portion of tissue, such as a blood vessel, is held between the porous electrodes, and fluid from a fluid source can pass through the porous electrodes. The tissue portion can be coagulated when electrical current is applied to the first and second porous electrodes, and an adjustable cutting element that is associated with the clamp members is positioned to cut a segment or all of the coagulated tissue portion. In this manner, the same surgical instrument is used to coagulate and cut tissue. | 05-14-2009 |
Katie Kane, Salem, MA US
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20110046522 | Ultrasound Energy Delivery Assembly - In a first embodiment, an ultrasound energy delivery assembly includes a waveguide and a catheter having a capture member. The capture member extends radially inward from an interior surface of the catheter into a lumen of the catheter and is configured to retain the enlarged distal tip so that the enlarged distal tip is temporarily prevented from moving proximally. In a second embodiment, an ultrasound energy delivery assembly includes a waveguide and a sheath covering at least a portion of the waveguide. In a third embodiment, an ultrasound energy delivery assembly includes a waveguide and a dual lumen catheter having a capture member. In a fourth embodiment, an ultrasound energy delivery assembly includes a waveguide and a catheter having a proximal waveguide lumen and a proximal guide wire lumen that merges with the proximal waveguide lumen at their respective distal ends to form a distal lumen. In a fifth embodiment, an ultrasound energy delivery assembly includes a waveguide and a catheter having a helical spring tip disposed over a distal section of the waveguide. In a sixth embodiment, an ultrasound energy delivery assembly includes a waveguide and a catheter extruded from a material such as expanded polytetrafluoroethylene. The catheter includes a braided layer having a multi-wire braided section and a single wire braided section formed from a braid wire from the multi-wire braided section. | 02-24-2011 |
Melanie Kane, Dorchester, MA US
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20130292976 | Receptacle With a Pocket for a Collapsible Chair - An apparatus comprising: a sleeve; and a pocket that is coupled to the sleeve; wherein the sleeve is configured to fit around a seat portion of a collapsible chair; wherein the pocket is configured to secure one or more items to the collapsible chair as the chair moves among a plurality of positions. | 11-07-2013 |
Nathan Kane, Arlington, MA US
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20080253935 | METHODS OF MANIPULATING SMALL AMOUNTS OF SOLIDS - The invention relates to methods and apparatuses for manipulating small amounts of solids. Specific embodiments of the invention are particularly suited for the automated transfer of small amounts of solids. In one embodiment, a uniform powder bed is lightly compressed into plugs of powder and dispensed. In another embodiment, the solid is placed in a liquid carrier to form a slurry, dispensed, and the liquid component is subsequently removed. In yet another embodiment, solids are manipulated using adhesive surfaces. | 10-16-2008 |
Nathan R. Kane, Arlington, MA US
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20090029527 | PROCESSES FOR FORMING BACKPLANES FOR ELECTRO-OPTIC DISPLAYS - A non-linear element is formed on a flexible substrate by securing the substrate to a rigid carrier, forming the non-linear element, and then separating the flexible substrate from the carrier. The process allows flexible substrates to be processed in a conventional fab intended to process rigid substrates. In a second method, a transistor is formed on a insulating substrate by forming gate electrodes, depositing a dielectric layer, a semiconductor layer and a conductive layer, patterning the conductive layer to form source, drain and pixel electrodes, covering the channel region of the resultant transistor with an etch-resistant material and etching using the etch-resistant material and the conductive layer as a mask, the etching extending substantially through the semiconductor layer between adjacent transistors. The invention also provides a process for forming a diode on a substrate by depositing on the substrate a first conductive layer, and a second patterned conductive layer and a patterned dielectric layer over parts of the first conductive layer, and etching the first conductive layer using the second conductive layer and dielectric layer as an etch mask. Finally, the invention provides a process for driving an impulse-sensitive electro-optic display. | 01-29-2009 |
20100265239 | PROCESSES FOR FORMING BACKPLANES FOR ELECTRO-OPTIC DISPLAYS - A non-linear element is formed on a flexible substrate by securing the substrate to a rigid carrier, forming the non-linear element, and then separating the flexible substrate from the carrier. The process allows flexible substrates to be processed in a conventional fab intended to process rigid substrates. In a second method, a transistor is formed on a insulating substrate by forming gate electrodes, depositing a dielectric layer, a semiconductor layer and a conductive layer, patterning the conductive layer to form source, drain and pixel electrodes, covering the channel region of the resultant transistor with an etch-resistant material and etching using the etch-resistant material and the conductive layer as a mask, the etching extending substantially through the semiconductor layer between adjacent transistors. The invention also provides a process for forming a diode on a substrate by depositing on the substrate a first conductive layer, and a second patterned conductive layer and a patterned dielectric layer over parts of the first conductive layer, and etching the first conductive layer using the second conductive layer and dielectric layer as an etch mask. Finally, the invention provides a process for driving an impulse-sensitive electro-optic display. | 10-21-2010 |
20110140744 | FLEXIBLE ELECTRONIC CIRCUITS AND DISPLAYS - A backplane for use in an electro-optic display comprises a patterned metal foil having a plurality of apertures extending therethrough, coated on at least side with an insulating polymeric material and having a plurality of thin film electronic devices provided on the insulating polymeric material. | 06-16-2011 |
Paul T. Kane, Whitinsville, MA US
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20100005033 | System and Method for In-Kind Rebalancing of Transactions - A system and method are described for an investor, such as a fund of funds, to advantageously perform portfolio rebalancing in a totally in-kind or combination in-kind/cash transaction that will at least minimize the transaction costs associated with rebalancing. | 01-07-2010 |
20120030141 | SYSTEM AND METHOD FOR IN-KIND REBALANCING OF TRANSACTIONS - A system and method are described for an investor, such as a fund of funds, to advantageously perform portfolio rebalancing in a totally in-kind or combination in-kind/cash transaction that will at least minimize the transaction costs associated with rebalancing. | 02-02-2012 |
Peter E. Kane, Westwood, MA US
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20140255615 | Apparatus and Process for Depositing a Thin Layer of Resist on a Substrate - The present inventions relate to the formation of a thin polymer film on a substrate. Apparatus is described for transforming a solid polymer resist into an aerosol of small particles, electrostatically charging and depositing the particles onto a substrate, and flowing the particles into a continuous layer. Apparatus is further described for transforming solid resist into an aerosol of small particles by heating the resist to form a low viscosity liquid such as is compatible with nebulization and applying the techniques of jet or impact nebulization and aerosol particle sizing to form the aerosol. A method is further described of using ionized gas to confer charge onto the aerosol particles and using a progression of charging devices establish an electric field directing the flow of charged particles to the substrate. The progression of charging devices and associated apparatus results in high collection efficiency for the aerosol particles. | 09-11-2014 |
20140367887 | METHODS AND APPARATI FOR HANDLING, HEATING AND COOLING A SUBSTRATE UPON WHICH A PATTERN IS MADE BY A TOOL IN HEAT FLOWABLE MATERIAL COATING, INCLUDING SUBSTRATE TRANSPORT, TOOL LAYDOWN, TOOL TENSIONING AND TOOL RETRACTION - A workpiece is transported using a porous belt, which belt delivers a workpiece to a chuck, upon which the workpiece is held by vacuum. The belt can be porous PTFE. A flexible stamp is preheated, before it is applied to a workpiece, by drawing the stamp toward a heated plate, for instance by vacuum. | 12-18-2014 |
Sheryl Kane, Somerville, MA US
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20140336593 | DRUG DELIVERY DEVICES AND METHODS OF USE THEREOF - Drug delivery devices are provided that are configured to release drug following passive or active activation of the device protecting the drug contained therein. In one aspect, the device may be configured to release a drug following selective application of light irradiation to the device. In another aspect, the device is configured to a release drug following degradation of at least a part of the device body that is formed, for example, from a bioerodible, hermetic material. An exemplary bioerodible, hermetic material is a biodegradable glass. Still other aspects provide for release of a drug upon a combination of both passive and active activation of the device. | 11-13-2014 |
Susan Kane, Beverly, MA US
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20120093837 | COMPOSITIONS AND METHODS FOR DETECTING EGFR IN CANCER - The invention discloses binding agents to the E746-A750 deletion and the L858R point mutations in the epidermal growth factor receptor (EGFR) molecule, and methods for use thereof, including methods for the diagnosis and treatment of cancer. | 04-19-2012 |
William J. Kane, Sutton, MA US
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20080228147 | Injector for use with pre-filled syringes and method of assembly - An injection device for use with a pre-filled syringe. The device features a track and track follower engagement which facilitates locking a protective needle guard over the tip of the needle at the conclusion of the injection. The device further includes a tamper evidence overcap which, once removed from the device cannot be readily reinstalled. The injection device features a tubular handle which is grasped by the hand and moved towards the injection site to administer the injection. The device is suitable for self-administration of injections. Use of the device is not technique dependent. Its design, including tubular handle which is grasped in one hand, is easy to use even by the elderly and persons with limited dexterity. | 09-18-2008 |
20100078459 | ELECTRONIC DISPENSER FOR DISPENSING SHEET PRODUCTS - A dispenser for dispensing sheet product includes a housing, a proximity sensor operative to detect a presence of a user's hand at a predetermined location near the dispenser, and a dispensing mechanism disposed within the housing, the dispensing mechanism including an electronic controller operably coupled to a drive motor that is operably coupled to a feed roller to dispense the sheet product. The dispensing mechanism is operative in a first mode to be responsive to a signal from the proximity sensor to dispense the sheet product, and is operative in a second mode to dispense a next sheet product in response to an existing sheet product being torn from the dispenser. The controller is responsive to a switch adapted and configured to set an adjustable time delay between sheet feeds when the dispensing mechanism is operating in at least one of the first mode and the second mode. | 04-01-2010 |