Patent application number | Description | Published |
20110158510 | BIOLOGICALLY-INSPIRED METADATA EXTRACTION (BIME) OF VISUAL DATA USING A MULTI-LEVEL UNIVERSAL SCENE DESCRIPTOR (USD) - A computer vision system provides a universal scene descriptor (USD) framework and methodology for using the USD framework to extract multi-level semantic metadata from scenes. The computer vision system adopts the human vision system principles of saliency, hierarchical feature extraction and hierarchical classification to systematically extract scene information at multiple semantic levels. | 06-30-2011 |
20130016584 | METHODS AND APPARATUS FOR OBTAINING SENSOR MOTION AND POSITION DATA FROM UNDERWATER ACOUSTIC SIGNALSAANM Zhou; JiangyingAACI DurhamAAST NCAACO USAAGP Zhou; Jiangying Durham NC USAANM Zachery; KarenAACI RaLeighAAST NCAACO USAAGP Zachery; Karen RaLeigh NC USAANM Qian; MingAACI CaryAAST NCAACO USAAGP Qian; Ming Cary NC USAANM Bogdanov; AlexanderAACI Simi ValleyAAST CAAACO USAAGP Bogdanov; Alexander Simi Valley CA US - Technologies are provided to recover motion, position, or navigation data of underwater sensors using bathymetry data. A method includes iteratively fitting data obtained by an underwater sensor from interactions between acoustic signals and an underwater floor, and deriving at least one of motion, position, or navigation data of the underwater sensor from the fitting. A standalone sonar can use the methods, systems, apparatuses, and computer programs to realize the derivation of motion, position, or navigation data without a position or motion sensor. | 01-17-2013 |
20140078061 | COGNITIVE BIOMETRICS USING MOUSE PERTURBATION - Cognitive biometrics comprises augmenting the richness of biometric signatures that can be extracted from mouse dynamics by introducing perturbations in the response of the computer mouse and measuring the motor responses of the individual user. User responses to unexpected and subtle perturbations (e.g., small changes in mouse velocity, position and/or acceleration) reveal new unique sources of information in the mouse movement signal that reflect the user's cognitive strategies and are inaccessible via existing mouse biometric technologies. A user's response to these perturbations contains information about intrinsic cognitive qualities that can be used as a robust biometric for personal authentication and to support profiling of the individual (e.g., gender, cultural background, cognitive or emotional state, cognitive quality etc.). | 03-20-2014 |
Patent application number | Description | Published |
20110075802 | FIELD EMISSION X-RAY SOURCE WITH MAGNETIC FOCAL SPOT SCREENING - An x-ray imaging system has an x-ray source having an electron field emission source that emits an x-ray beam that strikes an elongated, stationary anode in an evacuated housing. A magnetic deflection system steers the electron beam between the electron field emission source and the anode, so that the electron beam can strike the anode at different locations, thereby causing x-rays to be emitted from those different locations, by controlling the degree of magnetic deflection. A radiation detector detects the x-rays after attenuation by an examination subject, and generates signals dependent on the detected radiation that represent an image of the subject. | 03-31-2011 |
20110142316 | Tomography-Based and MRI-Based Imaging Systems - Tomography limitations in vivo due to incomplete, inconsistent and intricate measurements require solution of inverse problems. The new strategies disclosed in this application are capable of providing faster data acquisition, higher image quality, lower radiation dose, greater flexibility, and lower system cost. Such benefits can be used to advance research in cardiovascular diseases, regenerative medicine, inflammation, and nanotechnology. The present invention relates to the field of medical imaging. More particularly, embodiments of the invention relate to methods, systems, and devices for imaging, including tomography-based and MRI-based applications. For example, included in embodiments of the invention are compressive sampling based tomosynthesis methods, which have great potential to reduce the overall x-ray radiation dose for a patient. To name a few, compressive sensing based carbon nano-tube based interior tomosynthesis systems, tomography-based dynamic cardiac elastography systems, cardiac elastodynamic biomarkers from interior MR imaging, exact and stable interior ROI reconstructions for radial MRI, and interior reconstruction based ultrafast tomography systems are provided. | 06-16-2011 |
20120057678 | SYSTEMS AND METHODS FOR TEMPORAL MULTIPLEXING X-RAY IMAGING - The present subject matter relates to systems and methods for temporal multiplexing x-ray imaging of dynamic objects with high temporal resolution and fast imaging speed. A pulsed x-ray beam can irradiate an object undergoing a range of motion such as a cyclic motion. Multiple x-ray images can be acquired at different phases within a single motion cycle or range of the object. The multiple x-ray images can be demultiplexed to produce an individual phase image. Compared to sequential imaging, temporal multiplexing x-ray imaging can achieve high temporal resolution of dynamics object in multiple phases with imaging time comparable to that of a single phase. Temporal multiplexing x-ray imaging can thus be applied to a wide variety of applications, including biomedical imaging and industrial non-destructive testing. | 03-08-2012 |
Patent application number | Description | Published |
20080199626 | Method for assembling nano objects - A method for the self assembly of a macroscopic structure with a pre-formed nano object is provided. The method includes processing a nano object to a desired aspect ratio and chemical functionality and mixing the processed nano object with a solvent to form a suspension. Upon formation of the suspension, a substrate is inserted into the suspension. By evaporation of the solvent, changing the pH value of the suspension, or changing the temperature of the suspension, the nano objects within the suspension deposit onto the substrate in an orientational order. In addition, a seed crystal may be used in place of the substrate thereby forming single-crystals and free-standing membranes of the nano-objects. | 08-21-2008 |
20090022264 | STATIONARY X-RAY DIGITAL BREAST TOMOSYNTHESIS SYSTEMS AND RELATED METHODS - Stationary x-ray digital breast tomosynthesis systems and related methods are disclosed. According to one aspect, the subject matter described herein can include an x-ray tomosynthesis system having a plurality of stationary field emission x-ray sources configured to irradiate a location for positioning an object to be imaged with x-ray beams to generate projection images of the object. An x-ray detector can be configured to detect the projection images of the object. A projection image reconstruction function can be configured to reconstruct tomography images of the object based on the projection images of the object. | 01-22-2009 |
20100239064 | Methods, systems, and computer program products for multiplexing computed tomography - Methods, systems, and computer program products for multiplexing computed tomography are disclosed. According to one aspect, the subject matter described herein can include illuminating an object with a plurality of x-ray beams from a plurality of viewing angles, wherein each x-ray beam has a distinct waveform; detecting the x-ray intensities of the plurality of pulsed x-ray beams as a function of time, and extracting individual projection image data from the detected x-ray intensities based on the distinct waveforms of the x-ray beams for combining the projection image data to generate three-dimensional tomographic image data of the object. | 09-23-2010 |
20100329413 | COMPACT MICROBEAM RADIATION THERAPY SYSTEMS AND METHODS FOR CANCER TREATMENT AND RESEARCH - The present subject matter relates to compact, non-synchrotron microbeam radiation therapy (MRT) systems and methods for cancer research and treatment based on a carbon nanotube distributed x-ray source array technology. The systems and methods can deliver microscopically discrete x-ray radiation at peak dose rate of 10 Gy per second or higher. The x-ray radiation can be provided by a spatially distributed x-ray source array. The technology can be used, for example and without limitation, for human cancer treatment, for intra-operative radiation therapy, and for pre-clinical cancer research on animal cancer models. | 12-30-2010 |
20130170611 | HIGH SPEED, SMALL FOOTPRINT X-RAY TOMOGRAPHY INSPECTION SYSTEMS, DEVICES, AND METHODS - The present subject matter relates to inspection systems, devices and methods for x-ray inspection of objects. A conveyor can move an object to be inspected through an inspection zone along a direction of travel, one or more multibeam x-ray source arrays can provide multiple collimated x-ray beams through the inspection zone along a direction substantially perpendicular to the direction of travel, and one or more x-ray detector arrays can detect x-ray beams passing through the inspection zone from the x-ray source array. X-ray signals detected by the x-ray detector array can be recorded to form multiple x-ray projection images of the object, and the multiple x-ray projection images can be processed into three-dimensional tomographic images of the object. | 07-04-2013 |
20140119496 | COMPACT MICROBEAM RADIATION THERAPY SYSTEMS AND METHODS FOR CANCER TREATMENT AND RESEARCH - The present subject matter relates to compact, non-synchrotron microbeam radiation therapy (MRT) systems and methods for cancer research and treatment based on a carbon nanotube distributed x-ray source array technology. The systems and methods can deliver microscopically discrete x-ray radiation at peak dose rate of 10 Gy per second or higher. The x-ray radiation can be provided by a spatially distributed x-ray source array. The technology can be used, for example and without limitation, for human cancer treatment, for intra-operative radiation therapy, and for pre-clinical cancer research on animal cancer models. | 05-01-2014 |
Patent application number | Description | Published |
20100081620 | PRODOMAIN MODULATORS OF ADAM 10 - The presently disclosed subject matter discloses isolated ADAM 10 modulating peptides and related compounds useful for studying the biological functions of ADAM 10 and for the treatment of diseases such as cancer, neurological disorders, asthma, and allergic responses, and disorders characterized at least in part by the presence of one or more of inflammation, excess cell proliferation, angiogenesis, and excess soluble CD23. In one aspect, the presently disclosed subject matter provides isolated mouse and human ADAM 10 prodomain comprising the sequence set forth in SEQ ID NOs 1-8, or a sequence having at least 95% homology to any of SEQ ID NOs 1-8 and having the functionality of modulating ADAM 10 activity. | 04-01-2010 |
20120020991 | PRODOMAIN MODULATORS OF ADAM 10 - The presently disclosed subject matter discloses isolated ADAM 10 modulating peptides and related compounds useful for studying the biological functions of ADAM 10 and for the treatment of diseases such as cancer, neurological disorders, asthma, and allergic responses, and disorders characterized at least in part by the presence of one or more of inflammation, excess cell proliferation, angiogenesis, and excess soluble CD23. In one aspect, the presently disclosed subject matter provides isolated mouse and human ADAM 10 prodomain comprising the sequence set forth in SEQ ID NOs 1-8, or a sequence having at least 95% homology to any of SEQ ID NOs 1-8 and having the functionality of modulating ADAM 10 activity. | 01-26-2012 |
20130059788 | PRODOMAIN MODULATORS OF ADAM 10 - The presently disclosed subject matter discloses isolated ADAM 10 modulating peptides and related compounds useful for studying the biological functions of ADAM 10 and for the treatment of diseases such as cancer, neurological disorders, asthma, and allergic responses, and disorders characterized at least in part by the presence of one or more of inflammation, excess cell proliferation, angiogenesis, and excess soluble CD23. In one aspect, the presently disclosed subject matter provides isolated mouse and human ADAM 10 prodomain comprising the sequence set forth in SEQ ID NOs 1-8, or a sequence having at least 95% homology to any of SEQ ID NOs 1-8 and having the functionality of modulating ADAM 10 activity. | 03-07-2013 |
Patent application number | Description | Published |
20090055501 | Selective User Notification Based on IP Flow Information - An example embodiment of the present invention provides a process that uses IP flow information to selectively notify users of an application server of the server's unavailability. In the example embodiment, the process, which might run on a system comprising a router, monitors IP flow records as to dropped packets and learns that an application server has become unavailable. The process then uses the IP flow records to identify active users of the application server, for example, by passing a source IP address to a presence service. Once the process has identified an active user, the process determines a means of notification for the user, which might be through the presence service, and transmits a notification to the user as to the unavailability of the application server. In the example embodiment, the process transmits a later notification as to the availability of the application server, using reverse camp-on functionality. | 02-26-2009 |
20120136995 | Selective User Notification Based on IP Flow Information - An example embodiment of the present invention provides a process that uses IP flow information to selectively notify users of an application server of the server's unavailability. In the example embodiment, the process, which might run on a system comprising a router, monitors IP flow records as to dropped packets and learns that an application server has become unavailable. The process then uses the IP flow records to identify active users of the application server, for example, by passing a source IP address to a presence service. Once the process has identified an active user, the process determines a means of notification for the user, which might be through the presence service, and transmits a notification to the user as to the unavailability of the application server. In the example embodiment, the process transmits a later notification as to the availability of the application server, using reverse camp-on functionality. | 05-31-2012 |
Patent application number | Description | Published |
20080213324 | Amphiphilic or lipophilic polar functionalized fullerenes and their uses - Described herein are synthetically modified fullerene molecules, wherein the fullerene is preferably ellipsoid in shape with an equatorial band and two opposing poles, comprising an adduct at one or both poles, at least one adduct being a hydrophobic chemical moiety capable of anchoring the fullerene on or in a lipid membrane. | 09-04-2008 |
20080214514 | Steroid derivatives of fullerenes - Described herein are steroid derivatives of fullerene moieties, for example fullerene derivatives in which cholesterol, or a cholesterol moiety, is attached via ester, amide, or ether bonds to one of a variety of “linkers,” e.g., chemical groups including alkyl chains and aromatic groups, which are then connected to the fullerene moiety. The steroid moiety can confers useful solubility in components of biological fluids and/or pharmacologically acceptable carriers and can also affect the biodistribution of the fullerenes which makes the derivatives useful in imaging, diagnosis and the treatment or management of disease or complications of disease states. | 09-04-2008 |
20100286182 | HYDRAZIDE COMPOUNDS AS THYROID HORMONE RECEPTOR MODULATORS AND USES THEREOF - A method of identification of compounds that modulate thyroid hormone activity, and the use of such compounds and compositions thereof for such purposes are disclosed. The compounds may be selected from the group consisting of: | 11-11-2010 |
20110003773 | USING FULLERENES TO ENHANCE AND STIMULATE HAIR GROWTH - Described herein are methods for treating lack of hair growth or a reduction or loss of existing hair by stimulating and/or restoring hair growth, or preventing hair loss. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a fullerene. | 01-06-2011 |
20110021630 | METHOD FOR TREATING WOUNDS BY ADMINISTERING FULLERENES - Disclosed herein are methods for treating wounds. In one embodiment, the method comprises: administering to a subject in need thereof a therapeutically effective amount of a synthetically modified fullerene of the formula Z | 01-27-2011 |
20110028522 | FULLERENE THERAPIES FOR INFLAMMATION - Described herein are methods for treating inflammatory disorders. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a synthetically modified fullerene. | 02-03-2011 |
20110124848 | METALLOFULLERENE CONTRAST AGENTS - Endohedral metallofullerene compounds, which in water has a relaxivity of about 30 mM | 05-26-2011 |
20110190251 | METHOD FOR INHIBITING THE BUILD-UP OF ARTERIAL PLAQUE BY ADMINISTERING FULLERENES - Disclosed herein are methods of inhibiting the build-up of arterial plaque in a subject in need thereof. These methods comprise administering to the subject in need thereof a therapeutically effective amount of fullerenes. | 08-04-2011 |
20110251158 | FULLERENE THERAPIES FOR INFLAMMATION AND INHIBITION OF BUILD-UP OF ARTERIAL PLAQUE - Described herein are methods for treating inflammatory disorders or for inhibiting the build-up of arterial plaque. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a synthetically modified fullerene. | 10-13-2011 |
20140161733 | BIOMARKER-TARGETING CONTRAST AGENTS AND THEIR USE IN MAGNETIC RESONANCE IMAGING FOR DETECTION OF ATHEROSCLEROTIC PLAQUE - A composition comprising: a liposome having a bilayer structure, a gadofullerene having a high relaxivity, and an amphiphilic receptor ligand. In the composition, the gadofullerene is embedded in the bilayer structure of the liposome. In addition, a method for detecting atherosclerotic plaque in an animal using the composition is described. | 06-12-2014 |
Patent application number | Description | Published |
20090023038 | LIQUID MATERIALS FOR USE IN ELECTROCHEMICAL CELLS - Disclosed is the use of liquid precursor materials to prepare a processible polymeric electrolyte, which can be used to form a proton exchange membrane for use in an electrochemical cell. Also disclosed is the use of liquid precursor materials to prepare a processible catalyst ink composition, which can be conformally applied to a proton exchange membrane and a electrode material for use in an electrochemical cell. Also disclosed is the use of a photocurable perfluoropolyether (PFPE) material to form a microfluidic electrochemical cell. | 01-22-2009 |
20090216104 | USE OF ACID DERIVATIVES OF FLUOROPOLYMERS FOR FOULING-RESISTANT SURFACES - The presently disclosed subject matter describes acid-derivatized perfluoropolyether (PFPE) materials and their use as coatings, sealants, and flexible fillers for devices, apparatuses, and structural parts for a variety of medical applications, and as coatings, sealants, flexible fillers, and structural parts for vessels, structures, and machinery exposed to a marine environment. | 08-27-2009 |
20100147365 | HIGH FIDELITY NANO-STRUCTURES AND ARRAYS FOR PHOTOVOLTAICS AND METHODS OF MAKING THE SAME - A photovoltaic device includes an electron accepting material and an electron donating material. One of the electron accepting or donating materials is configured and dimensioned as a first component of a bulk heterojunction with a predetermined array of first structures, each first structure is substantially equivalent in three dimensional shape, has a substantially equivalent cross-sectional dimension, and where each first structure of the array of first structures has a substantially equivalent orientation with respect to adjacent first structures of the predetermined array forming a substantially uniform array. | 06-17-2010 |
20110215045 | HIGH FIDELITY THROUGH HOLE FILM, AND ASSOCIATED METHOD - A membrane is provided, comprising a first membrane layer having a first side and a second side. The first membrane layer defines a plurality of holes extending along a first axis between the first side and the second side. Each hole is defined by the first membrane layer as a complex three-dimensional shape, and each hole has a diameter of less than about 10 micrometers. The membrane is fabricated by dispersing a liquid polymeric material onto a patterned master template, hardening the polymeric material, and removing it from the master template. The membrane includes through holes which correspond to the structures of the patterned master template in size, cross-sectional and three dimensional shape, orientation, and the like. | 09-08-2011 |
20130249138 | HIGH FIDELITY NANO-STRUCTURES AND ARRAYS FOR PHOTOVOLTAICS AND METHODS OF MAKING THE SAME - A photovoltaic device includes an electron accepting material and an electron donating material. One of the electron accepting or donating materials is configured and dimensioned as a first component of a bulk heterojunction with a predetermined array of first structures, each first structure is substantially equivalent in three dimensional shape, has a substantially equivalent cross-sectional dimension, and where each first structure of the array of first structures has a substantially equivalent orientation with respect to adjacent first structures of the predetermined array forming a substantially uniform array. | 09-26-2013 |