Patent application number | Description | Published |
20080248592 | Detection of target analytes using particles and electrodes - The invention relates to the use of particles comprising binding ligands and electron transfer moieties (ETMs). Upon binding of a target analyte, a particle and a reporter composition are associated and transported to an electrode surface. The ETMs are then detected, allowing the presence or absence of the target analyte to be determined. | 10-09-2008 |
20080254548 | Detection of target analytes using particles and electrodes - The invention relates to the use of particles comprising binding ligands and electron transfer moieties (ETMs). Upon binding of a target analyte, a particle and a reporter composition are associated and transported to an electrode surface. The ETMs are then detected, allowing the presence or absence of the target analyte to be determined. | 10-16-2008 |
20110053788 | DETECTION OF TARGET ANALYTES USING PARTICLES AND ELECTRODES - The invention relates to the use of particles comprising binding ligands and electron transfer moieties (ETMs). Upon binding of a target analyte, a particle and a reporter composition are associated and transported to an electrode surface. The ETMs are then detected, allowing the presence or absence of the target analyte to be determined. | 03-03-2011 |
20120135530 | Detection of target analytes using particles and electrodes - The invention relates to the use of particles comprising binding ligands and electron transfer moieties (ETMs). Upon binding of a target analyte, a particle and a reporter composition are associated and transported to an electrode surface. The ETMs are then detected, allowing the presence or absence of the target analyte to be determined. | 05-31-2012 |
20140021066 | DETECTION OF TARGET ANALYTES USING PARTICLES AND ELECTRODES - The invention relates to the use of particles comprising binding ligands and electron transfer moieties (ETMs). Upon binding of a target analyte, a particle and a reporter composition are associated and transported to an electrode surface. The ETMs are then detected, allowing the presence or absence of the target analyte to be determined. | 01-23-2014 |
Patent application number | Description | Published |
20090069367 | METHODS FOR TREATMENT OF CANCER - A method for treating or preventing cancer in a subject comprising administering a treatment effective amount of a chemotype 4 compound. | 03-12-2009 |
20090075926 | METHOD FOR IDENTIFYING AND MANIPULATING CELLS - The present application discloses a method of isolating or selecting stem cells from a mixed population containing stem cells, which includes the population of cells with a ligand specific for a truncated MUC1 receptor, wherein the presence of the truncated MUC1 receptor on the cells indicates that they are stem cells. | 03-19-2009 |
20090092603 | EARLY DIAGNOSIS AND TREATMENT OF DRUG RESISTANCE IN MUC1-POSITIVE CANCER - A method of determining likelihood of acquiring drug resistance of a tumor or cancerous cells, cancer metastasis, cancer recurrence, or decreased life expectancy, comprising measuring the level of MUC1 or MUC1-associated factor expressed in the cancerous cells or tumor. | 04-09-2009 |
20100093092 | METHOD FOR INDUCING PLURIPOTENCY IN CELLS - The present application describes a method for inducing or maintaining pluripotency in a cell by contacting the cell with a biological or chemical species that increases MUC1* activity. | 04-15-2010 |
20100124789 | ELECTRONIC DETECTION OF INTERACTION AND DETECTION OF INTERACTION BASED ON THE INTERRUPTION FLOW - Porous members can be positioned so as to partially or fully span channels in microfluidic systems. The porous members can be assembled and/or disassembled in situ. The porous members can be made such that pores are separated by connections including but a single molecule at one location, allowing for a high level of open area in a very small pore size member. The porous member can be made up of colloid particles interconnected with molecular species. These can be used to detect analytes qualitatively and/or quantitatively, or to selectively bind and/or release agents on command for a variety of purposes including first blocking, then opening a channel, concentrating analyte over time followed by release of analyte and detection downstream, etc. Porous members can define valves in multiple-channel systems and, with controlled binding and release of agents at the porous members, these valves can be opened and closed and fluid flow controlled in a multi-channel system. Fluidic systems of the invention can include multiple sensing locations at which different analytes are determined. Systems of the invention provide flexibility for overall microchemical analysis, sequentially, of a variety of agents. | 05-20-2010 |
20100136017 | DIAGNOSTIC TUMOR MARKERS, DRUG SCREENING FOR TUMORIGENESIS INHIBITION, AND COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER - The invention provides a series of compositions, methods, kits, articles and species associated primarily with the diagnosis and/or treatment of cell proliferation, specifically cancer. Cell proliferation associated with aberrant expression of MUC1 is particularly focused upon. Mechanisms associated with MUC1 cell proliferation are discussed. | 06-03-2010 |
20100316688 | METHODS FOR CULTURING STEM AND PROGENITOR CELLS - The present application describes a method of culturing, expanding or growing stem or stem-like cells or induced pluripotent stem cells on a surface, including attaching the cells to the surface through a ligand that binds to the surface and the cells. | 12-16-2010 |
20110250616 | ELECTROACTIVE SURFACE-CONFINABLE MOLECULES - The invention provides compositions, kits, methods, and species that include electroactive entities which can serve as signaling entities in chemical and/or biochemical assays. The electroactive species can be metallocenes, such as ferrocenes, including substituents that affect the oxidation/reduction potential (redox potential) of the species. By controlling the redox potential of the species, multiple species can be used in a single assay, each species having a different redox potential, for simultaneous signaling of different binding events. Additionally, species having redox potentials lower than 490 mV can be provided, allowing signaling within a potential range easily detectable in the presence of biological fluids. | 10-13-2011 |