Pascale
Pascale Authouart, Les Trois Pierres FR
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20090186934 | Beta Crystalline form of the Arginine Salt of Perindopril, a Process for its Preparation and Pharmaceutical Compositions Containing it. - β-crystalline form of the compound of formula (I): | 07-23-2009 |
20090203758 | Alpha Crystalline form of the Arginine salt of Perindopril, a Process for its Preparation and Pharmceutical Compositions Containing it. - α-crystalline form of the compound of formula (I): | 08-13-2009 |
Pascale Beurdeley, Fonteay Sous Bois FR
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20120190577 | PROCESSES AND METHODS FOR DIAGNOSIS OF ALZHEIMER'S DISEASE - The present application relates to methods and compositions that can be used to diagnose Alzheimer's disease in mammals, most notably humans. Ti describes most notably peripheral blood biomarkers Alzheimer's disease and uses said biomarkers in diagnostic methods. It also relates to tools and/or kits that can be used to implement said methods (reagents, probes, primers, antibodies, arrays or chips, cells, etc.), as well as the preparation and use thereof. The invention can further be used to detect the presence or the advance of Alzheimer's disease in mammals, including during the disease's early phase, as well as to predict the effectiveness of an Alzheimer's disease treatment. | 07-26-2012 |
Pascale Beurdeley, Bois FR
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20110086776 | PROCESS AND METHOD FOR DIAGNOSING ALZHEIMER'S DISEASE - The present invention concerns methods and compositions usable for diagnosing Alzheimer's disease in mammals, in particular humans. It particularly describes serum markers for Alzheimer's disease and their use in diagnostic methods. It also concerns tools and/or kits usable for implementing these methods (reagents, probes, primers, antibodies, chips, cells, etc.), their preparation and their use. The invention is usable to detect the presence or progression of Alzheimer's disease in mammals, including in the early phase, as well as for predicting the efficacy of an Alzheimer's disease treatment. | 04-14-2011 |
Pascale Blouquin, Talant FR
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20100040682 | FENOFIBRATE TABLETS - The present invention relates to a novel galenic formulation of fenofibrate for oral administration and to the process for its preparation. | 02-18-2010 |
Pascale Bouillé, Escalquens FR
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20130029379 | VIRUS-BASED VECTOR COMPOSITIONS USEFUL FOR TRANSDUCING EUKARYOTIC CELLS - The present invention provides viral vector compositions of high titre and purity, as well as methods for production of said compositions. The methods of the invention incorporate multiple features, such as production of viral vector particles in serum free media and multiple harvesting steps following transduction of the producer cell which provides for enhanced production of said viral vectors. The viral vector compositions of the invention, by virtue of their high titre and purity, minimize the deleterious phenotypic changes that typically occur following transduction of target cells, such as loss of a sub-populations of transduced cells, and effects on proliferation, differentiation, reprogramming or functionality of transduced cells. | 01-31-2013 |
Pascale Bouillé, Escalquens FR
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20130029379 | VIRUS-BASED VECTOR COMPOSITIONS USEFUL FOR TRANSDUCING EUKARYOTIC CELLS - The present invention provides viral vector compositions of high titre and purity, as well as methods for production of said compositions. The methods of the invention incorporate multiple features, such as production of viral vector particles in serum free media and multiple harvesting steps following transduction of the producer cell which provides for enhanced production of said viral vectors. The viral vector compositions of the invention, by virtue of their high titre and purity, minimize the deleterious phenotypic changes that typically occur following transduction of target cells, such as loss of a sub-populations of transduced cells, and effects on proliferation, differentiation, reprogramming or functionality of transduced cells. | 01-31-2013 |
Pascale Burtin, Huningue FR
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20120264719 | DOSAGE REGIMEN OF AN S1P RECEPTOR MODULATOR - S1P receptor modulators are administered following a dosage regimen providing a positive benefit-risk profile. | 10-18-2012 |
20140187516 | DOSAGE REGIMEN OF AN S1P RECEPTOR MODULATOR - S1P receptor modulators are administered following a dosage regimen providing a positive benefit-risk profile. | 07-03-2014 |
Pascale Chazalnoel, Dremil-Lafage FR
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20110098194 | METHOD FOR DETECTING AND QUANTIFYING A MOLECULE INCLUDING AT LEAST ONE PROTONATED GROUP ON A SOLID SUBSTRATE - The present invention relates to a method for detecting and optionally quantifying at least one molecule comprising at least one protonated group such as an amine function immobilized at the surface of the solid substrate, said method being a reversible, direct and colorimetric method that uses a coloring agent. The present invention also relates to various uses of said method and the solutions used during said method. | 04-28-2011 |
Pascale Chenevier, Villebon Sur Yvette FR
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20110244585 | CHEMICAL SENSORS CONTAINING CARBON NANOTUBES, METHOD FOR MAKING SAME, AND USES THEROF - A device is disclosed for detecting at least one chemical compound comprising at least one carbon nanotube with several graphene layers, on which is grafted at least one molecule bearing group G1 capable of reacting with the chemical compound or a precursor of such a group G1. The uses and the method of making such a device is also disclosed. | 10-06-2011 |
20120114549 | METHOD AND KIT FOR SEPARATING METAL AND SEMICONDUCTOR CARBON NANOTUBES - A method for separating metal carbon nanotubes with a single graphene layer (m-SWNT) and semiconductor nanotubes with a single graphene layer (sc-SWNT) is provided. The method may comprise a step for grafting, notably by radical chemical grafting, a diazonium salt derivative on a mixture of m-SWNTs and sc-SWNTs so as to obtain a mixture of grafted m-SWNTs, and non-grafted sc-SWNTs, whereby the grafted m-SWNTs and the non-grafted sc-SWNTs separate because of differential chemical and/or physical properties caused by said grafting. In addition, a kit for separating m-SWNTs and sc-SWNTs is provided. | 05-10-2012 |
20140114079 | Method For Selective Functionalization Of Single-Walled Carbon Nanotubes - The present invention relates to a method for selective functionalization of metallic single-walled carbon nanotubes with a diazonium derivative. The present invention also relates to the use of the mixture of metallic single-walled carbon nanotubes selectively functionalized and to the semiconducting single-walled carbon nanotubes obtained by means of the method according to the invention, for producing transistor channels in particular in electronics, electron acceptor materials, in particular in photovoltaic systems, nonlinear infrared photon emitters or absorbers, current-conducting electrodes, flexible transparent electrodes, antistatic coatings, chemical detectors, and solar cells. | 04-24-2014 |
Pascale Claeys-Bouuaert, Bruxelles BE
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20130072597 | STORAGE STABLE WATER BASED EPOXY-AMINE CURABLE SYSTEMS - The invention relates to non aqueous curing agents for water dispersed epoxy resins. The curing agent composition offers a binder pot life of several hours, and in the presence of a metal, such as zinc, nearly no hydrogen generation is observed. The present curing composition can be mixed with a metal powder to provide a storage stable paste. The curing agent composition and/or paste is fully compatible with an epoxy water based resin. After low shear blending, the epoxy curing agent and metal system is storage stable for several hours working pot life that provides for cured coatings having good performance. | 03-21-2013 |
Pascale Cony-Makhoul, Annecy FR
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20090191606 | ORGANIC COMPOUNDS - The present invention relates to isolated polypeptides which comprise an amino acid sequence consisting of a mutated functional Abl kinase domain, said mutated functional kinase domain being resistant to inhibition of its tyrosine kinase activity by N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-4-(4-methyl-piperazin-1 -ylmethyl)-benzamide or a salt thereof, to the use of such polypeptides to screen for compounds which inhibit the tyrosine kinase activity of such polypeptides, to nucleic acid molecules encoding such polypeptides, to recombinant vectors and host cells comprising such nucleic acid molecules and to the use of such nucleic acid molecules in the production of such polypeptides for use in screening for compounds which inhibit the tyrosine kinase activity of such polypeptides. | 07-30-2009 |
20110129852 | ORGANIC COMPOUNDS - The present invention relates to isolated polypeptides which comprise an amino acid sequence consisting of a mutated functional Abl kinase domain, said mutated functional kinase domain being resistant to inhibition of its tyrosine kinase activity by N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-4-(4-methyl-piperazin-1-ylmethyl)-benzamide or a salt thereof, to the use of such polypeptides to screen for compounds which inhibit the tyrosine kinase activity of such polypeptides, to nucleic acid molecules encoding such polypeptides, to recombinant vectors and host cells comprising such nucleic acid molecules and to the use of such nucleic acid molecules in the production of such polypeptides for use in screening for compounds which inhibit the tyrosine kinase activity of such polypeptides. | 06-02-2011 |
Pascale Cothias, Montigny Le Bretonneux FR
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20080206164 | Cosmetic composition comprising at least one cationic polyurethane and at least one vinyl pyrrolidone homo- or copolymer, and method of styling therewith - The present disclosure relates to a cosmetic composition comprising, in a cosmetically acceptable aqueous medium: | 08-28-2008 |
20080206177 | Cosmetic composition comprising at least one cationic polyurethane and at least one polyethylene glycol ester, to be applied during hair dressing - The present disclosure relates to a cosmetic composition comprising in a cosmetically acceptable medium: | 08-28-2008 |
20090130028 | Cosmetic composition comprising a cationic polyurethane and a silicone, to be applied during hair dressing - The present disclosure relates to a cosmetic composition and hairstyling method comprising, in a cosmetically acceptable aqueous medium: | 05-21-2009 |
Pascale Dargelos, Billere FR
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20130281629 | NEW IMPACT MODIFIER AND IMPACT MODIFIED THERMOPLASTIC COMPOSITION - The invention relates to an impact modified thermoplastic resin comprising a polymeric impact modifier with a core-shell structure comprising 2-octylacrylate. | 10-24-2013 |
Pascale De Caro, Toulouse FR
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20100158835 | PLASTICIZER OF NATURAL ORIGIN FOR NAIL POLISH - The use of at least one carbonate of natural origin as a plasticizer in a film-forming cosmetic composition comprising, in a physiologically acceptable medium, a film-forming polymer and a solvent medium. | 06-24-2010 |
20140371487 | METHOD OF OXIDATIVE MOLECULAR CLEAVAGE OF A FATTY COMPOUND - A method of oxidative molecular cleavage of a fatty compound, includes: —forming a liquid composition, referred to as a fatty composition, consisting of at least one aliphatic carboxylic acid, the fatty composition including the fatty compound; characterised in that it then involves: —adding, to the fatty composition, a solution of at least one quaternary ammonium salt in water capable of forming an emulsion from the fatty compound and water, then; —adding, to the emulsion, a liquid solution of at least one tungstophosphoric acid in a composition including hydrogen peroxide (H | 12-18-2014 |
Pascale Delangle, Voiron FR
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20100234338 | CHELATING AGENTS OF METAL IONS, THEIR METHODS OF PREPARATION AND THEIR APPLICATIONS - The present invention relates to compounds that can be used as metal-ion-chelating agents or as depolluting agents, corresponding to general formula (I) below: | 09-16-2010 |
20130251639 | Novel Cyclodecapeptide Compounds For Use As Drugs - The invention relates to novel cyclodecapeptide compounds having formula (I) for use as drugs and, more specifically, for use in the diagnosis, prevention and/or treatment of neurodegenerative diseases, such as Wilson's disease and Alzheimer's disease, and for use in the diagnosis, prevention and/or treatment of poisoning with metal ions, such as copper and mercury ions. The invention also relates to pharmaceutical compositions comprising at least one compound having formula (I) as an active principle. | 09-26-2013 |
Pascale Demoment, Le Havre FR
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20080244963 | Lead-Free Aviation Fuel - Lead-free aviation fuel composition with a MON greater than 100, made up of a major component of a fuel made from Avgas and a minor component of at least two compounds from the group of esters of at least one mono-or poly-carboxylic acid and at least one mono- or polyol, anhydrides of a least one mono- or poly-carboxylic acid, preferably aromatic ethers at a level of at least 5% w/w and ketones at a level of more than 10% w/w. | 10-09-2008 |
20110114536 | AVIATION GASOLINE FOR AIRCRAFT PISTON ENGINES, PREPARATION PROCESS THEREOF - The subject of the present disclosure is an aviation gasoline composition that is lead-free and free of oxygenated compounds meeting the specifications of the ASTM standard comprising isopentane, isooctane, and (alkyl)aromatics. The aviation gasoline composition according to the disclosure may be obtained simply and economically from a mixture of hydrocarbon bases usually available in a refinery. | 05-19-2011 |
Pascale Dewalle, Vernon FR
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20130280132 | SMOKE ANALYSIS CHARACTERIZATION CELL - The invention relates to a smoke analysis characterization cell employing optical spectroscopy, which comprises: a reaction chamber, an inlet orifice for injecting smoke into the reaction chamber; an outlet orifice for discharging the smoke from the reaction chamber; and an analysis window for the entry of a laser beam intended to form the plasma inside the reaction chamber, which cell is characterized in that the system further includes a blower for blowing an inert gas close to the analysis window; and a shielding gas injector for the shielded injection of the smoke into the reaction chamber, the shielding being provided by a jet of inert gas around the smoke. | 10-24-2013 |
Pascale Dumont-Girard, Grenoble Cedex FR
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20100073122 | DUAL THIN FILM PRECISION RESISTANCE TRIMMING - A trimmable resistor for use in an integrated circuit is trimmed using a heater. The heater is selectively coupled to a voltage source. The application of voltage to the heater causes the heater temperature to increase and produce heat. The heat permeates through a thermal separator to the trimmable resistor. The resistance of the trimmable resistor is permanently increased or decreased when the temperature of the resistor is increased to a value within a particular range of temperatures. | 03-25-2010 |
Pascale Dumont-Girard, Grenoble FR
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20120266452 | DUAL THIN FILM PRECISION RESISTANCE TRIMMING - A trimmable resistor for use in an integrated circuit is trimmed using a heater. The heater is selectively coupled to a voltage source. The application of voltage to the heater causes the heater temperature to increase and produce heat. The heat permeates through a thermal separator to the trimmable resistor. The resistance of the trimmable resistor is permanently increased or decreased when the temperature of the resistor is increased to a value within a particular range of temperatures. | 10-25-2012 |
Pascale Dumont-Girard, Les Grollets FR
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20120112873 | VIALESS INTEGRATION FOR DUAL THIN FILMS - THIN FILM RESISTOR AND HEATER - A process is described for integrating two closely spaced thin films without deposition of the films through deep vias. The films may be integrated on a wafer and patterned to form a microscale heat-trimmable resistor. A thin-film heating element may be formed proximal to a thin-film resistive element, and heat generated by the thin-film heater can be used to permanently trim a resistance value of the thin-film resistive element. Deposition of the thin films over steep or abrupt topography is minimized by using a process in which the thin films are deposited in a sequence that falls between depositions of thick metal contacts to the thin films. | 05-10-2012 |
Pascale Ehouarn, Gif Sur Yvette FR
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20100297213 | Method For Making Patches By Electrospray - The invention relates to patches and methods for manufacturing patches intended for skin application of a substance wherein the patch includes a conductive support, and a liquid formulation of the substance is deposited on the support of the patch by electrohydrodynamic spraying. | 11-25-2010 |
20110046578 | DEVICE FOR THE CUTANEOUS APPLICATION OF SUBSTANCES - The invention relates to a device ( | 02-24-2011 |
Pascale Escafere, La Cote Saint Andre FR
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20120177888 | HIGH CELLULOSE CONTENT, LAMINIFEROUS NONWOVEN FABRIC - The present invention provides a laminiferous nonwoven fabric with a high woodpulp content suitable for use in wipes, absorbent articles and other applications, and a method of making the same. The laminiferous nonwoven comprises 3 layers bonded together, where the outer layers are lightweight meltspun webs and the middle layer comprises mainly woodpulp fibres. Each of the first ( | 07-12-2012 |
Pascale Fouqueray, Paris FR
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20100160410 | USE OF PENTADIENOIC ACID DERIVATIVES FOR THE TREATMENT OF HYPERURICEMIA - The use of a pentadienoic acid derivative of formula (I) for the preparation of a medicament for the prevention or treatment of hyperuricemia and/or one or several associated disorders or diseases, and/or for reducing the serum uric acid level of a subject. Medical compositions for these prevention and/or treatment, comprising such a pentadienoic acid derivative. | 06-24-2010 |
Pascale Fouqueray, Sins CH
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20130131065 | TREATMENT OF TYPE 2 DIABETES - The present invention relates to triazine derivatives of Formula I for their use in the treatment of Type 2 diabetes, and to compositions comprising said triazine derivatives. | 05-23-2013 |
20130131066 | TREATMENT OF TYPE 1 DIABETES - The present invention relates to triazine derivatives of formula (I) for their use in the treatment of type 1 diabetes mellitus, and to compositions comprising said triazine derivatives. | 05-23-2013 |
Pascale Gall-Borrut, Pignan FR
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20130298295 | NEAR-FIELD OPTICAL PROBE MANUFACTURING USING ORGANO-MINERAL MATERIAL AND SOL-GEL PROCESS - A method is provided for manufacturing near-field optical probes including at least one organo-mineral material with an organic part and a mineral part, the method including steps of irradiating at least partially the organo-mineral material with a radiation beam to polymerize the organic part in the irradiated areas, and polycondensing the mineral part by sol-gel process. Also disclosed are near-field optical probes and AFM and SNOM systems using the probes. | 11-07-2013 |
Pascale Gaussem, L'Hay Les Roses FR
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20090053693 | Identification of polymorphisms in the epcr gene associated with thrombotic risk - The invention relates to an in vitro method for determining the risk of developing thrombosis in a subject, which method involves identifying a particular haplotype EPCR gene. | 02-26-2009 |
Pascale Giraudon, Lyon FR
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20120027758 | USE OF ANTI-CD100 ANTIBODIES - The invention relates to the use a BD16 and/or BB18 anti-CD100 antibody or of a chimeric or humanized or human form thereof, or a fragment thereof, for the therapy or diagnosis of a central nervous system disorder, more particularly a myelin disorder or a disease that affects oligodendrocytes, such as multiple sclerosis or HTLV-1 associated myelopathy or peripheral myelinating cells. | 02-02-2012 |
20120135009 | Cleaved and Phosphorylated CRMP2 as Blood Marker of Inflammatory Diseases of the Central Nervous System - The present invention relates to a method for in vitro prognosis, diagnosis and/or monitoring of an inflammatory disease of the central nervous system in a subject, said method comprising detecting, in a sample of cells of the immune system from the subject, the presence of a Collapsin Response Mediator Protein 2 (CRMP2) which is phosphorylated on tyrosine 479 (Y479), and optionally further phosphorylated on serine 465 (S465), wherein the detection of the presence of Y479-phosphorylated CRMP2, which is optionally further phosphorylated on serine 465, is indicative of an inflammatory disease of the central nervous system. | 05-31-2012 |
Pascale Goberville, Paris FR
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20130131034 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS - The instant invention relates to derivatives of formula (I) | 05-23-2013 |
Pascale Goberville, Saint-Maur FR
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20120232081 | CYCLIC (AZA)INDOLIZINECARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS - The present invention relates to cyclic indolizinecarboxamides and azaindolizinecarboxamides of the formulae Ia and Ib, | 09-13-2012 |
Pascale Godon, Bruxelles BE
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20090286029 | Ethylene polymer composition - A polyethylene composition is disclosed having an unpigmented density of at least 946 kg/m | 11-19-2009 |
20100056728 | Polyethylene pipe fitting resins - A polyethylene resin suitable for formation into pipes or pipe fittings is disclosed, having an MI5 of from 0.40 to 0.70 g/10 min, and comprising from 47 to 52 wt % of a low molecular weight polyethylene friction, and from 48 to 53 wt % of a high molecular weight polyethylene fraction, wherein the high molecular weight polyethylene reaction comprises a copolymer of ethylene and | 03-04-2010 |
20120148775 | ETHYLENE POLYMER COMPOSITION - A polyethylene composition is disclosed having an unpigmented density of at least 946 kg/m | 06-14-2012 |
Pascale Gouker, Lexington, MA US
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20130056641 | SOLID-STATE NEUTRON DETECTOR WITH GADOLINIUM CONVERTER - Thermal Neutron Detector. The detector includes at least one semiconductor transistor within a circuit for monitoring current flowing through the semiconductor transistor. A film of gadolinium-containing material covers the semiconductor transistor whereby thermal neutrons interacting with the gadolinium-containing material generate electrons that induce a change in current flowing through the semiconductor transistor to provide neutron detection. | 03-07-2013 |
Pascale Grel, Viry-Chatillon FR
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20080201789 | VARIANTS AND EXONS OF THE GLYT1 TRANSPORTER - The present invention provides polypeptide and polynucleotide sequences for novel splice variants of the sodium and chloride-dependent glycine transporter type 1 (GlyT1). These polypeptides and polynucleotides are useful in the treatment and diagnosis of disorders such as neurological and psychiatric disorders including schizophrenia. The invention also provides antibodies directed specifically against these novel polypeptides, and kits comprising the herein-described polynucleotides, polypeptides, and/or antibodies. | 08-21-2008 |
Pascale Grenard, Bretigny FR
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20080214449 | Use of Antagonists of the Cbi Receptor For the Manufacture of a Composition Useful For the Treatment of Hepatic Diseases - The invention relates to the use of antagonists to the CB1 receptor for the preparation of a composition for the treatment of hepatic diseases and preferably to the use of N-piperidino-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide. | 09-04-2008 |
20090221692 | CB2 RECEPTORS BLOCKS ACCUMULATION OF HUMAN HEPATIC MYOFIBROBLASTS: A NOVEL ANTIFIBROGENIC PATHWAY IN THE LIVER - Methods for treating diseases of the livers mediated by CB2 receptors are described. The methods may include administering an effective amount of a cannabinoid, an agent that activates a CB2 receptor, a composition that includes a non-selective agonist of CB2 and a selective antagonist of CB1, a composition that includes an agonist of CB2 receptors, and/or a composition that includes an up-regulator of CB2 receptors to a patient who has liver fibrosis. | 09-03-2009 |
20120329833 | USE OF ANTAGONISTS OF THE CBI RECEPTOR FOR THE MANUFACTURE OF A COMPOSITION USEFUL FOR THE TREATMENT OF HEPATIC DISEASES - The invention relates to the use of antagonists to the CB1 receptor for the preparation of a composition for the treatment of hepatic diseases and preferably to the use of N-piperidino5 5-(4-chlorophenyl)-1-(2, 4-dichloropenyl)-4-methylpyrazole-3-carboxamide. | 12-27-2012 |
Pascale Gueirard, Meudon La Foret FR
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20100112009 | Acellular antibordetella vaccine - The invention relates to an immunogenic composition, characterized in that it comprises an adenyl cyclase-hemolysin (AC-Hly) protein, or an immunogenic portion of this AC-Hly, of a strain of | 05-06-2010 |
Pascale Hubert-Haddad, Sceaux FR
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20100278818 | Antibody specific for the Tn antigen for the treatment of cancer - The instant application provides a pharmaceutical composition comprising an antibody, directed against Tn antigen which comprises CDRs derived from 83D4 monoclonal antibody or an immunoconjugate of said antibody, said pharmaceutical composition being intended for the treatment of cancer. | 11-04-2010 |
Pascale Jacquemard, Saint Pierre De Chandleu FR
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20130337180 | METHOD OF FABRICATING A FRICTION PART BASED ON C/C COMPOSITE MATERIAL - A fiber preform made of carbon fibers is densified with a carbon matrix in a plurality of separate stages. After a first densification stage and before the end of carbon matrix densification, ceramic particles are introduced in order to be dispersed within the composite material part. The introduced particles have a mean size of less than 250 nm and are made at least of a ceramic compound of an element selected from titanium, yttrium, tantalum, and hafnium, the ceramic compound being selected from oxides, nitrides, and mixed oxide, carbide, and/or nitride compounds that do not react with carbon at a temperature of less than 1000° C. and that have a melting point higher than 1800° C. | 12-19-2013 |
Pascale Jacquemard, Saint Pierre De Chandieu FR
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20100015332 | METHOD OF FABRICATING A FRICTION PART OUT OF CARBON/CARBON COMPOSITE MATERIAL - A method of fabricating a friction part out of carbon/carbon composite material, the method including obtaining a three-dimensional fiber preform of carbon fibers impregnated with a solution or a suspension enabling a dispersion of refractory metal oxide particles to be left on the fibers of the preform; applying heat treatment to form a metallic carbide by a carboreduction reaction of the refractory oxide with the carbon of the fibers; continuing the heat treatment until the carbide is transformed into carbon by eliminating of the metal; and then densifying the preform with a carbon matrix by chemical vapor infiltration. | 01-21-2010 |
20100291373 | Part based on C/C composite material, and a method of fabricating it - After making a carbon fiber preform and prior to completing densification of the preform with a carbon matrix, impregnation is performed with a liquid formed of a sol-gel type solution and/or a colloidal suspension enabling one or more zirconium compounds to be dispersed. The impregnation and the subsequent treatment, up to obtaining the final part, are performed in such a manner as to have, in the final part, grains or crystallites of one or more zirconium compounds presenting a fraction by weight lying in the range 1% to 10% and of composition having at least a majority of the ZrO | 11-18-2010 |
Pascale Joesph, Montpellier FR
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20110306085 | COMPOSITIONS AND METHODS FOR DEGRADING LIGNOCELLULOSIC BIOMASS - The present invention relates to compositions and methods of producing bioenergy products and metabolites of industrial interest from lignocellulosic biomass. More specifically, the invention describes the identification, characterization and isolation of novel bacteria having the remarkable ability to transform lignocellulosic biomass into fermentable sugars and, even more remarkably, into bioenergy products and metabolites. The invention also discloses a method to isolate such bacteria, compositions comprising such bacteria, and their uses for the modification of lignocellulosic biomass, with a view to producing bioenergy. | 12-15-2011 |
Pascale Joetzjer, Louviers FR
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20100092412 | SELF TANNING COMPOSITIONS CONTAINING DIHYDROXYACETONE, A RETINOID AND ASCORBIC ACID GLUCOSIDE AS A STABILIZER - The invention concerns a composition comprising dihydroxyacetone, a retinoid and a glycosylated ascorbic acid. | 04-15-2010 |
Pascale Lazzeri-Vigouroux, Puyricard FR
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20090074690 | COSMETIC COMPOSITIONS COMPRISING AT LEAST ONE CATIONIC COPOLYMER AND AT LEAST ONE TRIGLYCERIDE AND METHODS OF USE THEREOF - The present disclosure relates to novel cosmetic compositions comprising, in a cosmetically acceptable medium | 03-19-2009 |
20090074692 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE CATIONIC COPOLYMER AND AT LEAST ONE ANIONIC ASSOCIATIVE POLYMER AND COSMETIC TREATMENT PROCESSES USING SAID COMPOSITION - The disclosure relates to novel cosmetic compositions comprising, in a cosmetically acceptable medium: | 03-19-2009 |
20090324526 | Compositions comprising madecassoside and/or terminoloside and an arginine and/or a salt and/or a derivative thereof for inducing and/or stimulating the growth of human keratin fibers and/or preventing loss thereof - Cosmetic care compositions for human keratin fibers contain, formulated into a physiologically acceptable medium: | 12-31-2009 |
20110061671 | METHOD FOR WASH-PROTECTING THE COLOR OF ARTIFICIALLY DYED KERATIN FIBERS - Disclosed herein is a method for wash-protecting the color of artificially dyed keratin fibers comprising applying to the artificially dyed keratin fibers at least one drying oil or at least one composition comprising, in a cosmetically acceptable medium, at least one drying oil. | 03-17-2011 |
Pascale Louise-Babando, Toulouse FR
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20090177400 | METHOD AND SYSTEM FOR PILOTING AN AIRCRAFT - The invention concerns a system ( | 07-09-2009 |
20130135202 | INTERACTIVE DIALOG DEVICE BETWEEN AN OPERATOR OF AN AIRCRAFT AND A GUIDANCE SYSTEM OF SAID AIRCRAFT - Interactive dialog device between an operator of an aircraft and a guidance system of the aircraft. The dialog device includes an interaction on a screen which represents, on the one hand, a playback element indicating the value of a guidance setpoint of the guidance system of the aircraft, and on the other hand, a control element which can be grasped and moved along a curve by an operator to modify the value of the guidance setpoint. | 05-30-2013 |
20130138272 | INTERACTIVE DIALOG DEVICE BETWEEN AN OPERATOR OF AN AIRCRAFT AND A GUIDANCE SYSTEM OF SAID AIRCRAFT - The dialog device includes a display screen, on which are displayed three graphic representations, which are respectively associated with the three control axes of the aircraft, each of said graphic representations comprising a plurality of portions, each of which is associated with a guidance mode of the associated control axis, so that all the possible guidance modes of the guidance system are thus represented, this representation highlighting the fact that the guidance modes are active exclusively on a given guidance axis. | 05-30-2013 |
Pascale Magat, Chilly Mazarin FR
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20100022548 | USE OF N-HETEROCYCLYLMETHYLBENZAMIDES IN THERAPEUTICS - The invention relates to use of compositions in therapeutics containing a compound having general formula (I): | 01-28-2010 |
20100234424 | DERIVATIVES OF N-PHENYL(PIPERIDINE-2-YL) METHYL BENZAMIDE PREPARATION METHOD THEREOF AND APPLICATIONS OF SAME IN THERAPEUTICS - Compounds of formula (I) as defined herein: | 09-16-2010 |
Pascale Marciniak-Davoult, Chatou FR
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20080245382 | Applicator for applying a composition to the eyelashes - The applicator for applying a composition to the eyelashes comprises | 10-09-2008 |
Pascale Mathonet, Cambridge GB
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20140005126 | SCAFFOLD PEPTIDES | 01-02-2014 |
Pascale Monti, Irigny FR
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20090082506 | Single-Constituent Polyorganosiloxane Composition Crosslinkable By Condensation And Comprising A Filler - The invention concerns a single-constituent polycondensation polyorganosiloxane composition comprising a filler. The invention concerns single-constituent polyorganosiloxane (POS) compositions storage-stable in the absence of humidity and crosslinkable, in the presence of water, into elastomer, compositions comprising at least one crosslinkable linear polyorganopolysiloxane POS, a filler and a crosslinking catalyst, the POS having alkoxy, oxime, acyl and/or enoxy, preferably alkoxy, ends, and the composition being essentially free of hydroxylated POS at the ends and the catalyst comprising a vanadium compound and a titanium compound. | 03-26-2009 |
Pascale Nabarra, Baziege FR
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20110251327 | Antistatic White Coating with a Hydroxylated Acrylic Base - An antistatic white paint suitable for application on spacecraft notably, based on a binder of the acrylic polymer type. | 10-13-2011 |
20110251328 | Silyl-Based Antistatic White Coating - An antistatic white paint suitable for application on spacecraft notably, based on a binder of the silicon polymer type. | 10-13-2011 |
Pascale Nagels, Brussels BE
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20100024695 | Fabrics - Fabric comprising a plurality of fibers (F) comprising at least one polymer material (P) selected from the group consisting of: | 02-04-2010 |
Pascale Neple, Leguevin FR
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20100123043 | SOUND INSULATING GLAZING DEVICE, IN PARTICULAR FOR AIRCRAFT AND SOUNDPROOFING METHOD FOR GLAZING - Sound insulating glazing device for aircrafts, ground or maritime transportation vehicles, buildings, or others, including glazing, a sealing joint in a shape and size corresponding to the edge of the glazing and designed for assembly on said edge, sound insulation, made of at least two materials, a first resilient material and a second material with less resilience than the first, the sound insulation being used against the field of said glazing, between the glazing and the sealing joint. The invention is also for aircrafts that are equipped with at least a glazing device and a soundproofing method for glazing. | 05-20-2010 |
Pascale Nouchi, Ville D'Avray FR
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20100021117 | Single-Mode Optical Fiber - Disclosed is an optical transmission fiber having reduced bending and microbending losses that is commercially usable in FTTH or FTTC transmission systems. | 01-28-2010 |
20100067859 | Single Mode Optical Fiber - An optical transmission fiber comprises a central core having an index difference Δn | 03-18-2010 |
20100189398 | Optical Fiber Preform - An optical fiber preform comprises a primary preform that includes at least one inner cladding and a central core deposited inside a fluorine doped silica tube. The fluorine doped silica tube has a cross section area that is no more than about 15 percent smaller than the cross section area of the primary preform. The optical fiber preform has a large capacity, may be manufactured at reduced cost, and may be drawn to produce an optical fiber having reduced transmission losses. | 07-29-2010 |
20100189928 | Method for Manufacturing an Optical Fiber Preform - A method for manufacturing an optical fiber preform includes the steps of depositing an inner cladding and a central core inside a fluorine doped silica tube and thereafter collapsing the silica tube to form a primary preform. The fluorine doped silica tube has a cross section area that is no more than about 15 percent smaller than the cross section area of the resulting primary preform. The present method facilitates reduced-cost manufacturing of a high-capacity optical fiber preform, which may be drawn to produce an optical fiber having reduced transmission losses. | 07-29-2010 |
20110164852 | Single-Mode Optical Fiber - Disclosed is an optical transmission fiber having reduced bending and microbending losses that is commercially usable in FTTH or FTTC transmission systems. | 07-07-2011 |
20110286710 | Single Mode Optical Fiber - An optical transmission fiber comprises a central core having an index difference Δn | 11-24-2011 |
Pascale Parrein, Fontaine FR
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20090147263 | INTERFERENCE SPECTROSCOPIC ANALYSIS DEVICE - The field of the invention is that of spectroscopic analysis devices allowing the spectral analysis of radiation. The device according to the invention is of the interference type, it comprises at least a first reflecting layer onto which is deposited a multilayer of alternately transparent and photo-absorbing thin films, each photo-absorbing layer being connected to electronic detection means supplying a primary electronic signal and the device also comprising means for analyzing the primary signals and configured in such a manner as to determine the spectral distribution of the original radiation. | 06-11-2009 |
20100207036 | OPTICAL IMAGING DEVICE - The invention concerns an optical imaging device for a human or animal body, including: an optical sensing system, a drive system of at least one light collector from the optical sensing system, permitting modification of at least the position and/or direction, and a control system from the drive system, arranged so as to lead the light collector from the optical sensing system to at least one observation situation of at least one chosen region of the body to be examined, based on data concerning its topology. | 08-19-2010 |
20120085944 | FILTERING MATRIX STRUCTURE, ASSOCIATED IMAGE SENSOR AND 3D MAPPING DEVICE - Filtering matrix structure comprising at least three color filters and a plurality of near Infrared filters, each one of the color filters and the near Infrared filters having an optimum transmission frequency, wherein the filtering matrix structure is made of n metal layers (m | 04-12-2012 |
Pascale Plas, Chatillon FR
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20090209531 | Pyrimido-Benzimidazole Derivatives and the Use Thereof in the Form of Agonists and Antagonists of Melanocortin Receptors - The invention relates to novel pyrimido-benzimidazole derivatives. Said products exhibit a good affinity for certain melanocortin receptor sub-types, in particular MC4 receptors. Said products represent a particular interest for treating pathological disorders and diseases associated with one or several melanocortin receptors. Pharmaceutical compositions containing said products and the use thereof for a drug preparation are also disclosed. | 08-20-2009 |
20090270372 | NOVEL DERIVATIVES OF BENZIMIDAZOLE AND IMIDAZO-PYRIDINE AND THEIR USE AS MEDICAMENTS - A subject of the present Application is novel derivatives of benzimidazole and imidazopyridine which have a good affinity for certain sub-types of melanocortin receptors, in particular the MC4 receptors. They are particularly useful for treating pathological conditions and diseases in which one or more melanocortin receptors are involved. The invention also relates to pharmaceutical compositions containing said products. | 10-29-2009 |
20120316201 | NOVEL BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AND USE THEREOF AS A MEDICAMENT - The invention relates to novel benzimidazole and imidazopyridine derivatives having the general Formula (I), which have a good affinity with certain subtypes of melanocortin receptors, particularly MC4 receptors. The derivatives are particularly suitable for the treatment of pathological states and diseases involving one or more melanocortin receptors. The invention also relates to pharmaceutical compositions containing said the compounds having the general Formula (I). | 12-13-2012 |
Pascale Reiniche, Golfe Juan FR
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20110165168 | CIDEA MODULATORS IN THE TREATMENT OF ACNE, OF SEBORRHOEIC DERMATITIS OR OF HYPERSEBORRHOEA - An in vitro or in vivo method for screening for candidate compounds for the preventive or curative treatment of acne, of seborrhoeic dermatitis or of skin disorders associated with hyperseborrhoea, includes determining the ability of a compound to modulate the expression or the activity of the CIDEA protein, and also utilizes modulators of the expression or of the activity of this protein, for the treatment of acne, of seborrhoeic dermatitis or of skin disorders associated with hyperseborrhoea; methods for the in vitro diagnosis of or in vitro prognosis for these pathologies are also featured. | 07-07-2011 |
20110262450 | MODULATORS OF MONOGLYCERIDE LIPASE IN THE TREATMENT OF ACNE, OF SEBORRHOEIC DERMATITIS OR OF HYPERSEBORRHOEA - An in vitro or in vivo method for screening for candidate compounds for the preventive or curative treatment of acne, of seborrhoeic dermatitis or of skin disorders associated with hyperseborrhoea, includes determining the ability of a compound to modulate the expression or the activity of monoglyceride lipase (MGLL), and also utilizes modulators of the expression or of the activity of this enzyme, for the treatment of acne, of seborrhoeic dermatitis or of skin disorders associated with hyperseborrhoea; methods for the in vitro diagnosis of or in vitro prognosis for these pathologies are also featured. | 10-27-2011 |
Pascale Resin, Le Locle CH
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20110105993 | Tools and Methods for Programming an Implantable Valve - Integrated tools for noninvasively reading and adjusting an implantable, magnetically adjustable valve, and methods of use are disclosed. The tools include magnetic or electronic reading of the valve, and magnetic or electromagnetic adjustment of the valve. In use, the tools are positioned above or in contact with the patient's skin, in proximity to the valve. | 05-05-2011 |
Pascale Senellart, Orsay FR
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20130048845 | POLARIZATION-ENTANGLED PHOTON PAIR SOURCE AND METHOD FOR THE MANUFACTURE THEREOF - An entangled photon pair source including: a quantum emitter having a ground state, two degenerate states that have one elementary excitation and different spins, and a state having two elementary excitations; a first optical cavity, wherein the quantum emitter is inserted; and a second optical cavity coupled with the first cavity. The geometry of the first and second cavities, and force of coupling thereof, are selected such that the whole formed by both coupled cavities has a first pair of polarization-degenerate modes, that are resonant with transitions between the state having two elementary excitations and the two degenerate states having one elementary excitation from the quantum emitter, and a second pair of polarization-degenerate modes that are resonant with transitions between the degenerate states, having one elementary excitation, and the ground state. | 02-28-2013 |
20130270596 | LIGHT SENSORS AND SOURCES COMPRISING AT LEAST ONE MICROCAVITY WITH A LOCALIZED TAMM PLASMON MODE - A light source or sensor including: a stack of dielectric or semiconductive layers includes an alternation in a vertical direction of layers of high refractive index and of low refractive index forming an interference mirror, and presenting a top layer of high refractive index; at least one first metal pellet deposited or transferred on the top layer of the stack of layers to form a structure supporting a first Tamm plasmon mode that is spatially localized in at least one lateral direction perpendicular to the vertical direction; and at least one light emitter or detector arranged inside the stack of layers under the metal pellet and at a depth corresponding to a local maximum of the electric field of the Tamm plasmon mode to emit or detect radiation at the resonant wavelength thereof. | 10-17-2013 |
Pascale Talamond, Eyragues FR
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20110046077 | PROCESS FOR THE EXTRACTION OF MANGIFERIN AND ISOMANGIFERIN - The present invention relates to methods for extracting and isolating glycosyl xanthone derivatives, in particular mangiferin and isomangiferin, from plants of the Rubiaceae family, especially of the | 02-24-2011 |
Pascale Tardieu, Paris FR
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20090232979 | Pigment-Colored Latex and Method for Treating a Clear Substrate with Said Colored Latex - The invention is dedicated to a colored latex comprising a mixture of an uncolored initial latex and at least one initial aqueous dispersion of at least one pigment being under the form of particles, wherein the particles of the pigment(s) are water-insoluble, and an amount of at least 90% of the particles of the one or more pigment(s) have a particle size of 370 nm or less, in the initial aqueous dispersion. | 09-17-2009 |
Pascale Tribout-Jover, Laval CA
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20120321694 | COMPOSITIONS AND USES - Compositions and methods comprising or using a combination of an adjuvant such as AS01B and an antigen such as a β-amyloid antigen are provided. The compositions and methods provided are particularly useful for prevention or treatment of Alzheimer's disease. Suitable β-amyloid antigens are Aβ1-5, Aβ1-6, Aβ1-7, Aβ1-10, Aβ1-14, Aβ1-15, Aβ2-7, Aβ2-8, Aβ3-7, Aβ3-8, Aβ11-16, Aβ11-17, Aβp(E)3-7, Aβp(E)3-8, Aβp(E)3-40, Aβp(E)3-42, Aβp(E)11-16, Aβp(E)11-17, Aβp(E)11-40 or Aβp(E)11-42, optionally with a protein carrier. Suitable adjuvants comprise QS21, 3D-MPL or an AGP, optionally in combination with a liposome. | 12-20-2012 |
20120328605 | COMPOSITIONS AND USES - The invention provides a TLR agonist and an antibody which binds to an antigen such as a β-amyloid antigen for use in stimulating an immune response to the antigen in an individual. The TLR agonist can be delivered at the same time as the antibody, less than 48 hours before the antibody or after the antibody. The compositions and methods provided are useful for prevention or treatment of Alzheimer's disease. | 12-27-2012 |
20130216614 | IMMUNOGENIC COMPOSITIONS AND METHODS FOR TREATING NUEROLOGIC DISORDERS - The present invention relates to methods and compositions for preventing and reducing amyloid deposition in a subject by administering to the subject a composition containing aTLR4 agonist free of endotoxin, where the composition does not contain beta amyloid. | 08-22-2013 |
20140294849 | COMPOSITIONS AND USES - The invention provides a TLR agonist and an antibody which binds to an antigen such as a β-amyloid antigen for use in stimulating an immune response to the antigen in an individual. The TLR agonist can be delivered at the same time as the antibody, less than 48 hours before the antibody or after the antibody. The compositions and methods provided are useful for prevention or treatment of Alzheimer's disease. | 10-02-2014 |
Pascale Vicat-Blanc Primet, Lyon FR
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20120284396 | DIAGNOSTIC TOOL FOR BROADBAND NETWORKS - A local pre-transfer agent, that can be run on a local computer including RAM, one central processing unit, and one interface communicating with a data exchange network connected to the RAM by a communication bus. The agent includes a first function establishing a first predictive value of the data transmission or reception bandwidth limit from configuration data on the memory, a second function establishing a second predictive value of bandwidth limit from configuration data of the processing unit, a third function establishing a third predictive value of bandwidth limit from bus configuration data, a fourth function establishing a fourth predictive value of bandwidth limit from configuration data of the communication interface, and a hardware diagnostic function invoking each one these functions and establishing, from the resulting predictive values, a bandwidth reference value in accordance with predefined comparison rules for said predictive values. | 11-08-2012 |
20130132546 | TOOL FOR MANAGING RESOURCES AND COMPUTER INFRASTRUCTURES AND NETWORKS - A tool for aiding management of a communicating physical device includes: a device controller operating the physical device using operating parameters; a data storage interlinking an identifier from the physical device and dated values of attributes and a list of control functions capable of modifying some of the operating parameters; an interpreter adapted for receiving a device identifier datum and a time horizon parameter at the same time and for responding thereto by establishing a series of respective events using the information from the data storage, related to the time horizon, each event interlinking a date, one or more identifiers of control functions, and parameters for these functions, established in accordance with a dated attribute value; and a sequencer arranged to call the interpreter and carry out chronologically the calls of the functions of each event of the series as returned by the interpreter. | 05-23-2013 |
Pascale Vicat-Blanc-Primet, San Francisco, CA US
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20130073732 | TOOL FOR MANAGING COMPUTER RESOURCES AND INFRASTRUCTURES AND NETWORKS - A tool for aiding utilization of communicating equipment includes a resources manager associated with a data structure where an equipment identifier is connected with dated values of utilizable global functional capability of the resource, and dated values of temporarily allocated functional capability. A scheduling tool evaluates an acceptance condition by comparing dates which pertain to a dated functional capability and to the dated series of functional capability maintained in connection with one or more resource identifiers. A resources allocator receives an identified request for temporary reservation of functional capabilities, including a dated suite of functional data, it responds thereto by calling a resources selector for each functional data item of the request, the scheduling tool for some at least of the identifiers of the subset returned by the resources selector; and by returning a set of resource identifiers as response to the reservation request. | 03-21-2013 |
20130091180 | TOOL FOR MANAGING COMPUTER RESOURCES AND INFRASTRUCTURES AND NETWORKS - A tool for assisting the operation of a network of interconnected physical equipment includes a physical infrastructure manager associated with a first data structure in which the equipment items are registered under a resource identifier in relation to a first sequence of dated values of global utilizable functional capacity, and a virtual infrastructure manager associated with a second data structure in which virtual units are registered under a unit identifier in relation to a second sequence of dated values of global utilizable functional capacity, and with a third data structure in which a virtual unit identifier is associated with a group of resource identifiers and hence with the corresponding sequences of dated capacity values. The virtual infrastructure manager dynamically reconfigures a virtual infrastructure object in accordance with the rights and capacities requested by a user. | 04-11-2013 |
Pascale Ythier-Moury, Paris FR
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20120238605 | OTAMIXABAN FOR TREATMENT OF ELDERLY AND RENAL IMPAIRED NON-ST ELEVATION MYOCARDIAL INFARCTION PATIENTS - The invention relates to the use of (2R,3R)-2-(3-carbamimidoyl-benzyl)-3-[4-(1-oxy-pyridin-4-yl)benzoylamino]-butyric acid methyl ester or a pharmaceutically acceptable salt thereof, for the preparation of a medicament for use in non-ST elevation myocardial infarction, said treatment comprising administering a therapeutically effective amount of (2R,3R)-2-(3-Carbamimidoyl-benzyl)-3-[4-(1-oxy-pyridin-4-yl)benzoylamino]-butyric acid methyl ester or a pharmaceutically acceptable salt thereof to a human patient, who is elderly and/or shows renal insufficiency and/or has a low body weight. | 09-20-2012 |