Diss
James K. J. Diss, London GB
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20090074665 | Diagnosis and treatment of cancer:I - A method of diagnosing cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of SCN5A (and optionally also SCN9A) voltage-gated Na+ channel nucleic acid or protein associated with cancer. A method of diagnosing breast cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of voltage-gated Na+ channel nucleic acid or protein, preferably SCN5A or SCN9A, associated with cancer. A method of treating cancer comprising the step of administering to the patient an agent which selectively prevents the function of SCN5A (and optionally also SCN9A) voltage-gated Na+ channel. A method of treating breast cancer comprising the step of administering to the patient an agent which selectively prevents the function of a voltage-gated Na+ channel, preferably SCN5A or SCN9A. Genetic constructs and molecules useful in such methods. The methods and compositions are particularly suited to breast cancer. | 03-19-2009 |
20100273866 | DIAGNOSIS AND TREATMENT OF CANCER: I - A method of diagnosing cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of SCN5A (and optionally also SCN9A) voltage-gated Na+ channel nucleic acid or protein associated with cancer. A method of diagnosing breast cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of voltage-gated Na+ channel nucleic acid or protein, preferably SCN5A or SCN9A, associated with cancer. A method of treating cancer comprising the step of administering to the patient an agent which selectively prevents the function of SCN5A (and optionally also SCN9A) voltage-gated Na+ channel. A method of treating breast cancer comprising the step of administering to the patient an agent which selectively prevents the function of a voltage-gated Na+ channel, preferably SCN5A or SCN9A. Genetic constructs and molecules useful in such methods. The methods and compositions are particularly suited to breast cancer. | 10-28-2010 |
Matthew Diss, Basingstoke GB
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20150149885 | Systems and Methods for Contextual Vocabularies and Customer Segmentation - Contextual vocabulary and methods of use are provided herein. A method may include obtaining contextual properties for a plurality of end users and device related information for computing devices used by the plurality of end users, the contextual information being obtained from a plurality of ambient information sources, including selection from a plurality of contextual repositories. Also, the method includes calculating a trust level for each of the plurality of customer analytic information sources and each of the plurality of device information databases, and building a contextual vocabulary from the contextual information and the device related information selected based upon their trust levels. | 05-28-2015 |
20150149886 | SYSTEMS AND METHODS THAT UTILIZE CONTEXTUAL VOCABULARIES AND CUSTOMER SEGMENTATION TO DELIVER WEB CONTENT - Systems and methods for dynamically delivering web content are provided herein. A method may include determining behavior analytics of an end user and device related information for a first computing device used by the end user, as well as comparing the behavior analytics, and other contextual information, of an end user and the device related information for the first computing device used by the end user to a contextual vocabulary that includes context segments that define contextual information of a plurality of end users and device related information for computing devices used by the plurality of end users. The method includes generating a context segment path for an end user, the context segment path having a plurality of context segments that have been selected from the contextual vocabulary, and dynamically creating a web page having web content that is selected and formatted based upon the context segment path. | 05-28-2015 |
Nicolas Diss, Strabourg FR
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20090325757 | AUTOMATIC TRANSMISSION - An automatic transmission is provided with a torque converter clutch (TCC) for regulating the slip between the engine speed and the transmission input speed and a method is provided for regulating the slip between the engine speed and the transmission input speed in an automatic transmission with a torque converter clutch. In order to improve the first time shift quality of transmissions, it is proposed that means are provided for learning the valve pressure offset. In first tests it could be stated that the first time shift quality can be considerably improved with a short test which takes place at the end of the vehicle production line. The longer the test time, the better the first time shift quality will be. | 12-31-2009 |
Nicolas Diss, Strasbourg FR
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20090197736 | PROCESS FOR CALIBRATING AN AUTOMATIC TRANSMISSION - A method is provided for calibrating an automatic transmission with a torque converter clutch. In order to avoid that the torque converter clutch still has capacity even if the pressure is commanded to be zero without modifying the behavior of the torque converter clutch behavior of all the production, the torque converter clutch minimum offset transmissions are detected and only on these transmissions the torque converter minimum clamp pressure is decreased by a pressure step and the torque converter clutch coast adapt reference cell is increased. | 08-06-2009 |
Pascal Diss, Le Haillan FR
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20080311301 | Protection Against the Oxidation of Composite Materials Containing Carbon - A part made of a porous material containing carbon, in particular a C/C composite material, is protected against oxidation by being impregnated with a composition in an aqueous medium containing at least a phosphorous compound, elemental titanium, and boron or a boron compound other than titanium diboride, to form in the presence of oxygen and at least one alkali or alkaline-earth element M that catalyses oxidation of carbon, at least one P—O—Ti-M type association bonded by boron oxide B | 12-18-2008 |
20110311804 | PROCESS FOR PRODUCING A SELF-HEALING LAYER ON A PART MADE OF A C/C COMPOSITE - In order to provide a self-healing layer on a composite material part, a composition is applied to the part, the composition containing: a suspension of colloidal silica; boron or a boron compound in powder form; silicon carbide in powder form; and at least one ultra-refractory oxide. | 12-22-2011 |
Thomas S. Diss, Waukesha, WI US
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20090212004 | VACUUM CONTAINER WITH PROTECTIVE FEATURES - A container including a metal sidewall is provided. The metal sidewall includes a first end; a second end; a center portion having a principal width; a first feature positioned between the center portion and the first end, the first feature extending from the sidewall such that the maximum width of the sidewall at the first feature is greater than the principal width; and a second feature positioned between the center portion and the second end, the second feature extending from the sidewall such that the maximum width of the sidewall at the second feature is greater than the principal width. The container further includes a first bead located in the center portion of the sidewall; and a second bead located in the center portion of the sidewall. | 08-27-2009 |
20120145584 | VACUUM CONTAINER WITH PROTECTIVE FEATURES - A container including a metal sidewall is provided. The metal sidewall includes a first end; a second end; a center portion having a principal width; a first feature positioned between the center portion and the first end, the first feature extending from the sidewall such that the maximum width of the sidewall at the first feature is greater than the principal width; and a second feature positioned between the center portion and the second end, the second feature extending from the sidewall such that the maximum width of the sidewall at the second feature is greater than the principal width. The container further includes a first bead located in the center portion of the sidewall; and a second bead located in the center portion of the sidewall. | 06-14-2012 |