Kasko
Andrea M. Kasko, Boulder, CO US
Patent application number | Description | Published |
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20140031285 | PHOTODEGRADABLE GROUPS FOR TUNABLE POLYMERIC MATERIALS - Here, we present a photodegradable microparticle system that can be employed to entrap and deliver bioactive proteins to cells during culture. By using a photosensitive delivery system, experimenters can achieve a wide variety of spatiotemporally regulated release profiles with a single microparticle formulation, thereby enabling one to probe many questions as to how protein presentation can be manipulated to regulate cell function. Photodegradable microparticles were synthesized via inverse suspension polymerization with a mean diameter of 22 μm, and degradation was demonstrated upon exposure to several irradiation conditions. The protein-loaded depots were incorporated into cell cultures and release of bioactive protein was quantified during the photodegradation process. This phototriggered release allowed for the delivery of TGF-β1 to stimulate PE25 cells and for the delivery of fluorescently labeled Annexin V to assay apoptotic 3T3 fibroblasts during culture. By incorporating these photoresponsive protein delivery depots into cell culture, new types of experiments are now possible to test hypotheses about how individual or multiple soluble factors might affect cell function when presented in a uniform, temporally varying, or gradient manner. | 01-30-2014 |
Igor Kasko, Dresden DE
Patent application number | Description | Published |
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20090267042 | Integrated Circuit and Method of Manufacturing an Integrated Circuit - According to one embodiment of the present invention, an integrated circuit including a plurality of resistance changing memory cells is provided. Each memory cell includes: a semiconductor substrate; a select device arranged within the semiconductor substrate; and a memory element being arranged above the semiconductor substrate. The select device is a diode comprising a first semiconductor area of a first conductive type and a second semiconductor area of a second conductive type which are arranged adjacent to each other such that a lateral pn-junction is formed. The first semiconductor area is connected to a word line arranged on or above the semiconductor substrate. The second semiconductor area is connected to the memory element via a conductive connection element. | 10-29-2009 |
20090303780 | INTEGRATED CIRCUIT INCLUDING AN ARRAY OF DIODES COUPLED TO A LAYER OF RESISTANCE CHANGING MATERIAL - An integrated circuit includes an array of diodes and an electrode coupled to each diode. The integrated circuit includes a layer of resistance changing material coupled to the electrodes and bit lines coupled to the layer of resistance changing material. The layer of resistance changing material provides a resistance changing element at each intersection of each electrode and each bit line. | 12-10-2009 |
Igor Kasko, Dresden FR
Patent application number | Description | Published |
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20090073743 | Method of Manufacturing a Memory Cell, Memory Cell, Integrated Circuit, and Memory Module - A method of fabricating a memory cell including a solid electrolyte layer doped with metallic material and an electrode layer arranged above the solid electrolyte layer. The method includes doping a solid electrolyte layer with metallic material and forming an electrode layer above the solid electrolyte layer, wherein doping the solid electrolyte layer is carried out before forming the electrode layer. | 03-19-2009 |