Patent application number | Description | Published |
20140031387 | LFA-1 INHIBITOR AND METHODS OF PREPARATION AND POLYMORPH THEREOF - Methods of preparation and purification of a compound of Formula I, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed. | 01-30-2014 |
20150336939 | LFA-1 INHIBITOR AND METHODS OF PREPARATION AND POLYMORPH THEREOF - Methods of preparation and purification of a compound of Formula I, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA-1 mediated diseases are also disclosed. | 11-26-2015 |
20160024069 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF A PDE10 INHIBITOR - The present invention is directed to an improved process for the preparation of compounds of Formula (II) and Formula (III), which are useful in the inhibition of PDE10. In particular, the present invention is directed to an improved process for the preparation of 1-(5-(4-chloro-3,5-dimethoxyphenyl)furan-2-yl)-2-ethoxy-2-(4-(5-methyl-1,3,4-thiadiazol-2-yl)phenyl)ethanone, which is useful in the inhibition of PDE10. | 01-28-2016 |
Patent application number | Description | Published |
20090069428 | CATALYTIC ANTIOXIDANTS AND METHODS OF USE - The invention provides small molecules that act as catalytic antioxidants and methods of use thereof. The compounds can repeatedly bind and destroy reactive oxygen species by serving as substrates for enzymes of the methionine sulfoxide reductase (Msr) class. Some embodiments of the catalytic antioxidant compounds are derived from drugs with anti-inflammatory activity due to inhibition of cyclooxygenase enzymes. | 03-12-2009 |
20090326073 | PROTECTION OF NORMAL CELLS - The invention provides compositions comprising sulindac, R-epimer sulindac, S-epimer sulindac, derivatives, metabolites, and structural analogs thereof which protect normal cells against damage caused by solar rays, oxidative damage, environmental factors, diseases and organisms. | 12-31-2009 |
20140018429 | PROTECTION OF NORMAL CELLS - The invention provides compositions comprising sulindac, R-epimer sulindac, S-epimer sulindac, derivatives, metabolites, and structural analogs thereof which protect normal cells against damage caused by solar rays, oxidative damage, environmental factors, diseases and organisms. | 01-16-2014 |
Patent application number | Description | Published |
20100204853 | FLIGHT CONTROL SYSTEM AND AIRCRAFT COMPRISING IT - The flight control system comprises:
| 08-12-2010 |
20100222943 | FLIGHT CONTROL SYSTEM AND AIRCRAFT COMPRISING IT - The flight control system comprises:
| 09-02-2010 |
20110276199 | FLIGHT CONTROL SYSTEM AND AIRCRAFT COMPRISING IT - A flight control system for an aircraft, in which control commands are transmitted between a flight control module ( | 11-10-2011 |
20140100718 | FLIGHT CONTROL SYSTEM USING SIMPLEX COMPUTERS AND AIRCRAFT COMPRISING SAME - A system for computing flight commands, which comprises simplex computers coupled to form virtual command/monitor pairs. These virtual pairs send the commands computed to actuators whose controller implements an election of the pair whose command will be taken into account by the actuator. | 04-10-2014 |
20140236395 | DEVICE FOR MAKING AVAILABLE NAVIGATION PARAMETER VALUES OF A VEHICLE - A device for making available navigation parameter values of a vehicle is provided. The device includes components distributed in the following categories: several sensors collecting measurement data relating to at least one navigation parameter of the vehicle; several computers processing the measurement data collected by the sensors and calculating said navigation parameters; several networks linking the sensors to the computers and linking the computers to systems using said parameters. The networks transmit all the collected measurement data to the computers, which calculate a value for each navigation parameter as well as an estimated value of the associated fault, using a single common fusion algorithm. | 08-21-2014 |
20150148997 | METHOD FOR FUSING DATA FROM SENSORS USING A CONSISTENCY CRITERION - The disclosure relates to a data fusion method for fusing the measurements of a parameter, for example an aircraft flight parameter, that are taken by a plurality of sensors comprising a set of main sensors and sets of secondary sensors. The discrepancy between each main measurement and the secondary measurements is determined and a score of consistency with them is deduced therefrom. For each fault configuration of the main sensors, a first estimation, so-called conditional, of the parameter is performed and a weighting coefficient relating to this fault is calculated, taking account of the consistency scores of the main measurements. The parameter is thereafter estimated by performing a combination of the conditional measurements with the associated weighting coefficients. | 05-28-2015 |