Wang, FL
Alvin Wang, Alachua, FL US
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20140178351 | COMPOSITIONS AND METHODS RELATING TO ARGININOSUCCCINATE SYNTHETASE - Processes and compositions for the therapeutic treatment of pathogenic Gram-negative bacterial infection are provided whereby arginino succinate synthetase or PEGylated arginino succinate synthetase is administered to a subject to inactivate endotoxin thereby reducing the likelihood of bacterial sepsis and improving patient outcome. | 06-26-2014 |
Chin-Cheng (james) Wang, Gainesville, FL US
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20130038199 | SYSTEM, METHOD, AND APPARATUS FOR MICROSCALE PLASMA ACTUATION - A device is provided having a flow passage with at least one surface and at least one electrode pair positioned thereon for effecting fluid flow through the flow passage. When at least one electrode of an electrode pair of the at least one electrode pair is powered, a sheath region is generated in the flow passage, wherein the sheath region has a high electric field relative to the remainder of the flow passage. In an embodiment, one electrode of the electrode pair is separated from the other electrode of the electrode pair by a horizontal, vertical, depth, and/or total distance of about 1 microns. | 02-14-2013 |
Chunlei Wang, Miami, FL US
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20140029161 | ELECTROCHEMICALLY ACTIVATED C-MEMS ELECTRODES FOR ON-CHIP MICRO-SUPERCAPACITORS - Disclosed herein are methods of manufacturing micro-super capacitors from C-MEMS structures. | 01-30-2014 |
20140031253 | Protein Detection Using Three-Dimensional Carbon Microarrays - The potential of aptamers as ligand binding molecule have opened new avenues in the development of biosensors for proteins, such as cancer oncoproteins. Disclosed herein is a label-free detection strategy using signaling aptamer/protein binding complex for proteins, such as platelet-derived growth factor (PDGF-BB) oncoprotein. The detection mechanism is based on the release of a fluorophore (e.g., TOTO intercalating dye) from the target binding aptamer's stem structure when it captures the protein, e.g., PDGF. Amino-terminated three-dimensional carbon microarrays fabricated by pyrolyzing patterned photoresist are used as a detection platform. The sensor showed near linear relationship between the relative fluorescence difference and protein concentration even in the sub-nanomolar range with an excellent detection limit of 5 pmol. This detection strategy is promising in a wide range of applications in the detection of cancer biomarkers and other proteins. | 01-30-2014 |
Chunlei Wang, Pembroke Pines, FL US
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20150179356 | HYBRID ELECTROCHEMICAL CAPACITOR - Hybrid electrochemical capacitors, electronic devices using such capacitors, and associated methods are disclosed. In an example, a hybrid electrochemical capacitor can include a first electrode made from Mg, Na, Zn, Al, Sn, or Li, a second electrode made from a porous material such as porous carbon or passivated porous silicon, and an electrolyte. The hybrid electrochemical capacitors can have enhanced voltage and energy density compared to other electrochemical capacitors, and enhanced power density compared to batteries. | 06-25-2015 |
Chunyan Wang, Tampa, FL US
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20130224860 | THREE-DIMENSIONAL FIBROUS SCAFFOLDS FOR CELL CULTURE - Provided herein is a three-dimensional scaffold composition comprising randomly oriented fibers, wherein the fibers comprise a polyethylene glycol-polylactic acid block copolymer (PEG-PLA) and a poly(lactic-co-glycolic acid) (PLGA). Also provided are methods for using the three-dimensional scaffolds described herein. | 08-29-2013 |
20130230496 | GRAPHENE HYDROGEL AND METHOD FOR USING THE SAME - Provided herein is a hydrogel composition comprising a graphene, a chitosan, and a polyethylene (glycol) diacrylate (PEGDA) (PCG hydrogel). In some embodiments, the hydrogel further comprises a N-isopropylacrylamide (NIPAM) (TPCG hydrogel). Also provided is a method for differentiating a mesenchymal stem cell comprising contacting the cell with the PCG hydrogel. Further provided herein is a method for delivering a pharmaceutical composition to a cell comprising administering to the cell a TPCG hydrogel and the pharmaceutical composition. | 09-05-2013 |
20130230595 | Methods of Using Multilayer Magnetic Micelle Compositions - Provided herein is a method of transfecting a brain cell of a subject with a polynucleotide comprising systemically administering to the subject a composition comprising a micelle having a hydrophobic superparamagnetic iron oxide nanoparticle (SPION) core, a first coating comprising a cationic polymer, and a second coating comprising the polynucleotide, wherein the subject has a mild traumatic brain injury. | 09-05-2013 |
20130243867 | MICELLE COMPOSITIONS AND METHODS FOR THEIR USE - Provided herein is a micelle composition comprising a polyethylene glycol (PEG), a DC-cholesterol, and a dioleoylphosphatidyl-ethanolamine (DOPE) and either or both a pharmaceutical compound core and a polynucleotide coating. Also provided herein is a method of administering one or more compounds to a cell comprising administering to the cell a micelle composition comprising 1) PEG-PE, a DC-cholesterol, and DOPE, and 2) the one or more compounds, wherein the compounds are selected from the group consisting of a polynucleotide and a pharmaceutical composition. Further provided are methods for detecting the micelle composition. | 09-19-2013 |
20130330384 | MOLECULARLY IMPRINTED POLYMERS HAVING AFFINITY FOR NATRIURETIC PEPTIDES - The present invention concerns molecularly imprinted polymers (MIPs) having an affinity for natriuretic peptides, such as atrial natriuretic peptide (ANP). In some embodiments, the MIP is a nanoparticle (a molecularly imprinted polymeric nanoparticle (MIPNP)). Other aspects of the invention include methods of preparing an MIP having affinity for a natriuretic peptide, methods for binding a natriuretic peptide in vitro or in vivo using an MIP of the invention, methods for interfering with the binding of a natriuretic peptide with its receptor in vivo, methods for reducing inflammation, cell growth, cell differentiation, or a cell proliferation disorder, methods for detecting natriuretic peptides, and devices and kits for sequestering and/or detecting natriuretic peptides. | 12-12-2013 |
20150064116 | MULTILAYERED MAGNETIC MICELLE COMPOSITIONS AND METHODS FOR THEIR USE - Provided herein are compositions comprising a micelle having a hydrophobic superparmagnetic iron oxide nanoparticle (SPION) core, a first coating comprising a cationic polymer, and a second coating comprising a polynucleotide. Also provided are methods of using the compositions for transfection and/or transformation of a cell with the polynucleotide. Further provided are methods of detecting transfection of a cell with the polynucleotide. | 03-05-2015 |
Daniel Wang, Jacksonville, FL US
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20110054927 | AUTOMATED OPHTHALMIC LENS AND SOLUTIONS DISPENSING UNIT - The present invention discloses methods and apparatus for dispensing ophthalmic lenses and solutions and replenishing those lenses physically or virtually dispensed. In addition, in some embodiments, a patient may prepare an order for lenses and solutions dispensed. | 03-03-2011 |
Daniel T. Wang, Jacksonville, FL US
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20100181332 | APPARATUS AND METHOD FOR DISTRIBUTING OPHTHALMIC LENSES - An apparatus for dispensing ophthalmic lens packages and methods of its use are described herein. | 07-22-2010 |
20100187249 | APPARATUS AND METHOD FOR DISTRIBUTING OPHTHALMIC LENSES - An apparatus for dispensing ophthalmic lens packages and methods of its use are described herein. | 07-29-2010 |
Di Wang, Gainesville, FL US
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20150095141 | METHOD, APPARATUS, AND COMPUTER PROGRAM PRODUCT FOR FACILITATING MARKETING BETWEEN BUSINESSES - A method, apparatus and computer program product are provided for facilitating a marketing interlock between businesses. Two or more businesses may enter into a co-marketing campaign in which a sponsoring entity funds an advertisement of a sponsored entity on a third party advertising system, such as a search engine. Marketing content of the sponsoring entity is inserted on the website of the sponsored entity. Traffic originating on the third party advertising system may therefore first be driven to the sponsored entity's website, and subsequently to the sponsoring entity's website, thereby achieving a mutually beneficial co-marketing relationship. Marketing relationships among complimentary businesses based on provided service and location may also be facilitated according to the methods provided. | 04-02-2015 |
Dingding Wang, Miami, FL US
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20090300486 | MULTIPLE-DOCUMENT SUMMARIZATION USING DOCUMENT CLUSTERING - Systems and methods are disclosed for summarizing multiple documents by generating a model of the documents as a mixture of document clusters, each document in turn having a mixture of sentences, wherein the model simultaneously representing summarization information and document cluster structure; and determining a loss function for evaluating the model and optimizing the model. | 12-03-2009 |
20100185943 | COMPARATIVE DOCUMENT SUMMARIZATION WITH DISCRIMINATIVE SENTENCE SELECTION - Systems and methods are disclosed for summarizing a plurality of documents, by extracting sentence candidates from the documents; dividing the documents into one or more groups; selecting one or more discriminant sentences for each group using a discriminant criterion; and generating one or more summaries for the one or more groups based on the selected sentences. | 07-22-2010 |
Frank C. Wang, Boca Raton, FL US
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20130332565 | CONTENT DELIVERY SYSTEM AND METHOD - A content delivery system and method for use with plurality of digital multimedia data processing systems and legacy systems spanning across one or more network environments. The system and method enable users with freedom of mobility while maintaining access to the user's selected content while the user transitions from one device in one location to a different device in a difference location, substantially without interruption and without the need for user action to turn on and off these target data processing systems. The Instant Invention can provide high bandwidth content delivery solutions based upon hardware and software components by activating a Target device while the system is proximate to the Target device and, in one embodiment, automatically redirecting the content while the system is proximate to a new Target device without user intervention. The Target devices include digital multimedia data processing systems and legacy systems including, but not limited to, HDTVs, TV, Personal Computers, digital music systems, printers, radios, and fax machines. | 12-12-2013 |
20150058409 | ENHANCED CONTENT DELIVERY SYSTEM AND METHOD SPANNING MULTIPLE DATA PROCESSING SYSTEMS - An enhanced content delivery system and method for use with plurality of digital multimedia data processing systems and legacy systems spanning across one or more network environments. The system and method enable users with freedom of mobility while maintaining access to the user's selected content while the user transitions from one device in one location to a different device in a difference location, substantially without interruption and without the need for user action to turn on and off these target data processing systems. The Instant Invention can provide high bandwidth content delivery solutions based upon hardware and software components by activating a Target device while the system is proximate to the Target device and, in one embodiment, automatically redirecting the content while the system is proximate to a new Target device without user intervention. The Target devices include digital multimedia data processing systems and legacy systems including, but not limited to, HDTVs, TV, Personal Computers, digital music systems, printers, radios, and fax machines. | 02-26-2015 |
20150149587 | ENHANCED CONTENT CONTINUATION SYSTEM AND METHOD - A content delivery system and method for use with plurality of digital multimedia data processing systems and legacy systems spanning across one or more network environments. The system and method enable users with freedom of mobility while maintaining access to the user's selected content while the user transitions from one device in one location to a different device in a difference location, substantially without interruption and without the need for user action to turn on and off these target data processing systems. The Instant Invention can provide high bandwidth content delivery solutions based upon hardware and software components by activating a target device while the system is proximate to the target device and, in one embodiment, automatically redirecting the content while the system is proximate to a new target device without user intervention. The target devices include digital multimedia data processing systems and legacy systems including, but not limited to, HDTVs, TV, Personal Computers, digital music systems, printers, radios, and fax machines. | 05-28-2015 |
Gary P. Wang, Gainesville, FL US
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20160022745 | BUTYROGENIC BACTERIA AS PROBIOTICS TO TREAT CLOSTRIDIUM DIFFICILE - The subject invention pertains to the use of certain bacterial strains, particularly butyrogenic bacteria, for preparing a composition to treat and/or prevent | 01-28-2016 |
Guoxin Wang, Mulberry, FL US
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20080197053 | FROTH FLOTATION PROCESS WITH pH MODIFICATION - This invention relates to the pH modifier in alkaline froth flotation processes to treat oxide and semi-soluble salt ores, such as phosphates, sulfates, carbonates and halides, to increase the recovery while generally maintaining or improving selectivity, thus the grade of desired minerals. The invented pH modifier is used to replace traditional alkaline pH modifiers—hydroxides, carbonates and bicarbonates, such as sodium hydroxide, sodium carbonate, lime and ammonia in anionic flotation processes. The pH modifier is aqueous solution, comprised of combinations of sodium hydroxide, sodium carbonate, and sodium silicate, along with sulfonated surfactant products, such as sulfonated petroleum oil, fatty acids, alkylates, ethoxylated alcohol ethers, and also sulfosuccinamates; and anionic polymers. The pH modifier is also used as a promoter for anionic collectors and as a depressant for gangue minerals. | 08-21-2008 |
20110226701 | ENHANCING SEDIMENTATION PERFORMANCE OF CLARIFIERS/THICKENERS - Some mineral processing plants encounter difficulties in dewatering pulps using clarifier/thickener (C/T) equipment due to a layer of fine particles, air bubbles and chemicals formed at the top of the liquid in the thickener. Such layers are very stable and form a cap on the C/T. The dewatering performance of the C/T then deteriorates under these conditions, and a high percentage of solids is contained in the thickener overflow. A process for removing water from rock slurry containing a wide range of particle sizes in mineral processing operations has been developed. The process includes: (a) classifying the feed slurry into two size fractions, namely a coarse fraction and a fine fraction, (b) treating the fine fraction (and the coarse fraction if required) with a selected flocculant, and (3) thickening the flocculated slurry in sedimentation equipment to separate liquid from solids. | 09-22-2011 |
20110278496 | DEFOAMING COMPOSITION FOR HIGH ACID STRENGTH MEDIA - All natural defoaming compositions useful in high strength acid media utilizing phosphatide emulsifiers that are considerably more effective at reduced application rates than prior art compositions are described. | 11-17-2011 |
Hong-Gang Wang, Tampa, FL US
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20110130568 | Acylsulfonamides and Processes for Producing the Same - The present disclosure relates to acylsulfonamides and processes for their preparation. The processes involve a target-guided synthesis approach, whereby a thioacid and a sulfonyl azide are reacted in the presence of a biological target protein, a Bcl-2 family protein, to form the acylsulfonamide. | 06-02-2011 |
Huai Y. Wang, Coconut Creek, FL US
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20090004972 | METHOD FOR OPERATING A WIDE AREA NETWORK MODEM AND A PERSONAL AREA NETWORK MODEM IN A MOBILE COMMUNICATION DEVICE - A mobile communication device ( | 01-01-2009 |
20090005111 | METHOD AND APPARATUS FOR PERFORMING NEIGHBOR SCANS ON A WIDE AREA NETWORK IN A MOBILE COMMUNICATION DEVICE OPERATING A PERSONAL AREA NETWORK - A mobile communication device ( | 01-01-2009 |
20090034444 | METHOD FOR TRANSITIONING A WIDE AREA NETWORK MODEM OF A MOBILE COMMUNICATION DEVICE BETWEEN A POWER SAVING MODE AND A SCAN MODE - A mobile communication device ( | 02-05-2009 |
Jia Wang, Tampa, FL US
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20090125392 | Method of displaying auction listing information on auction calendar using asynchronous Web service - A method was designed to facilitate the advertisement of land auction listings for an online audience. The method includes displaying auction listing information on the Auction Calendar using Asynchronous Web Service. Wherein the advertised auction events are displayed according to the advertisement period on the graphically presented calendar. An Asynchronous Web Service is implemented to organize a user-orientated interface to automatically provide a list of auction events from the server without interrupting the user's actions. The listing is displayed as the user places the cursor over the dates in the calendar. The method allows the user to update the date and view the auction listings for a chosen date in real-time, to filter and manipulate the auction event data without refreshing the page. | 05-14-2009 |
Jianhua Wang, Miami, FL US
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20140300862 | INDICES FOR MANAGEMENT OF DRY EYE SYNDROME, CORNEAL ECTASIA, KERATOPLASTY GRAFT REJECTION AND FAILURE AND FUCHS' DYSTROPHY - Improved indices for the diagnosis and evaluation of conditions affecting the eye. Specifically, the indices include an Enhanced Epithelial Irregularity Factor (eEIF) for the diagnosis and evaluation of conditions such as dry eye syndrome (DES), Bowman's Ectasia Index (BEI), including enhanced BEI (eBEI) and BEI-Max, and Bowman's Relative Thinning (BRT) Index for the diagnosis and evaluation of ectatic conditions such as keratoconus, pellucid marginal degeneration, post-refractive surgery ectasia, and keratoglobus, and Descemet's Membrane Thickening Index (DMT), Descemet's Rejection Index (DRI), and Descemet's Membrane Irregularity Factor (DIF) for the diagnosis and evaluation of conditions such as keratoplasty rejection and failure and Fuchs' dystrophy. These improved indices may be incorporated into optical coherence tomography systems, or any other imaging device capable of capturing high resolution images of the cornea, for more sensitive and specific diagnosis, treatment, and monitoring of certain corneal conditions, in addition to the evaluation of new treatments. | 10-09-2014 |
20140358011 | SINGLE SHOT HIGH RESOLUTION CONJUNCTIVAL SMALL VESSEL PERFUSION METHOD FOR EVALUATING MICROVASCULATURE IN SYSTEMIC AND OCULAR VASCULAR DISEASES - A system and method for generating high-resolution, small vessel perfusion maps (nCPMs) of the ocular conjunctival microvasculature. Unlike current systems and methods, the present invention allows for the generation of nCPMs using only a single raw image obtained in a single image acquisition step. The method includes obtaining a single raw image of at least a portion of the microvasculature of the ocular conjunctiva. The raw image may be obtained using a digital camera and slit lamp. The red and blue color channels are removed from the raw image to create a color-adjusted image in which contrast between the microvasculature and the sclera is enhanced. The color-adjusted image is then inverted and saved as a grayscale inverted image. The grayscale inverted image may be skeletonized. The grayscale image and/or the skeletonized image may be quantitatively analyzed. | 12-04-2014 |
Jianping Wang, Gainesville, FL US
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20130198912 | DNA SEQUENCE THAT CONFERS APHID RESISTANCE IN SOYBEAN - Provided herein are isolated nucleic acid molecules representing a genetically defined region of the genome of the aphid resistant soybean plant ( | 08-01-2013 |
20130305410 | RHG1 MEDIATED RESISTANCE TO SOYBEAN CYST NEMATODE - Methods of increasing the resistance of plants, in particular soybeans, to nematodes, in particular soybean cyst nematodes, are provided herein. The methods include increasing the expression of Glyma18g02580, Glyma18g02590 and/or Glyma18g2610 in cells of a plant and in particular in root cells of a plant to increase the resistance of the plant and plant cells to nematodes. The methods include increasing the expression using constitutive promoters or by increasing the copy number of the polynucleotides. Constructs for expressing these polypeptides, transgenic cells, transgenic plants and methods of generating the same are also provided. Methods of screening plant cells for resistance or susceptibility to nematodes are also provided. | 11-14-2013 |
Jia-Wang Wang, Tampa, FL US
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20100266548 | LPS-Responsive CHS1/Beige-Like Anchor Gene and Therapeutic Applications Thereof - The present invention relates to a novel LPS-responsive and Beige-like Anchor gene (lrba), variants of the lrba gene, fragments of the lrba gene, and polypeptides encoded thereby. The subject invention also pertains to lrba interfering RNA, and uses thereof. In another aspect, the present invention also includes methods of inhibiting tumor growth in a patient by suppressing lrba function. | 10-21-2010 |
20100286249 | Micro-RNAS Modulating Immunity and Inflammation - MicroRNAs are shown to be up- and/or down-regulated in inflammation and immune cells using a mouse model of asthma and regulatory T cells as source of RNA, respectively. Modulating the expression of these microRNAs can be effective in redirecting inflammation and immunity and hence, can be beneficial as biomarkers or as therapeutic agents against diverse human immunologic and inflammatory diseases. | 11-11-2010 |
20120289420 | MICRORNA BIOMARKERS FOR AIRWAY DISEASES - The present invention provides miRNA biomarkers useful for diagnosis, prognosis, and/or treatment of airway diseases such as asthma, asthma exacerbation and nasal polyps. | 11-15-2012 |
20130045885 | MATERIALS AND METHODS FOR PROFILING MICRORNAS - The present invention provides materials and methods for detecting, quantifying, and/or profiling microRNAs. Advantageously, the present invention is sensitive, specific, convenient, and cost-effective. In one embodiment, the present invention provides a universal primer for reverse transcription of miRNAs, a universal reverse primer for PCR amplification reaction, and a universal probe. In another embodiment, the present invention provides assays that allow the detection and/or quantification of a plurality of target miRNAs using a single reverse transcription reaction and a single qPCR reaction. | 02-21-2013 |
20130216605 | MICRO-RNAS MODULATING IMMUNITY AND INFLAMMATION - MicroRNAs are shown to be up- and/or down-regulated in inflammation and immune cells using a mouse model of asthma and regulatory T cells as source of RNA, respectively. Modulating the expression of these microRNAs can be effective in redirecting inflammation and immunity and hence, can be beneficial as biomarkers or as therapeutic agents against diverse human immunologic and inflammatory diseases. | 08-22-2013 |
20140004520 | MATERIALS AND METHODS FOR PROFILING MICRORNAS | 01-02-2014 |
Jonathan Wang, Galnesville, FL US
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20110097392 | ANTIBODY BOUND SYNTHETIC VESICLE CONTAINING MOLECULES FOR DELIVER TO CENTRAL AND PERIPHERAL NERVOUS SYSTEM CELLS - A process is provided of delivering at least one active agent cargo molecule into an neuronal cell whereby a cargo molecule is placed within a synthetic vesicle such as a liposome and a biotinylated protein such as an antibody is bound to the synthetic vesicle to form a protein bound synthetic vesicle whereby the protein recognizes a receptor expressed on the surface of a neuronal cell, and exposing the protein bound synthetic vesicle to the cell until the cargo molecule is delivered into the neuronal cell. Numerous cargo molecules are delivered by the inventive synthetic vesicle including a calpain inhibitor and a caspase inhibitor. The protein illustratively targets a cellular receptor for a ligand such as glutamate, glycine, dopamine, nicotine, muscarine, acetylcholine, or serotonin, and the like. | 04-28-2011 |
Kai-Wei Wang, Gainesville, FL US
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20100326891 | SEPARATION OF CARBON NANOTUBE BUNDLES VIA INTERFACIAL TRAPPING - In embodiments of the invention, bundles of carbon nanotubes are separated from individual nanotubes via interfacial trapping of bundled carbon nanotube bundles at an emulsion interface between suspension-phase and a solution-phase. The separation method comprises dispersing a mixture of individual and bundled carbon nanotubes in a solution comprising surfactant; adding at least one solvent to the surfactant solution to form a two-phase mixture; agitating the two-phase mixture to form an emulsion interface between the solution-phase and a suspension-phase, where nanotube bundles selectively segregate to the emulsion interface. Single-walled carbon nanotube suspensions exhibit strong fluorescence, which can be used to assess the degree of separation and determine if a repeated extraction of any remaining bundled carbon nanotubes remaining in the suspension-phase is desired. In another embodiment of the invention, separation of carbon nanotubes by type is carried out by interfacial trapping. | 12-30-2010 |
Ka-Wang (kevin) Wang, Gainesville, FL US
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20090317805 | Proteolytic Markers as Diagnostic Biomarkers for Cancer, Organ Injury and Muscle Rehabilitation/Exercise Overtraining - The present invention identifies biomarkers that are diagnostic of nerve cell injury, organ injury, and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury. | 12-24-2009 |
20100047817 | Synaptotagmin and Collapsin Response Mediator Protein as Biomarkers for Traumatic Brain Injury - Collapsin response mediator proteins (CRMPs) decreased in tissue and increased in biological fluids after neural injury from traumatic brain injury (TBI). Significant decreases of CRMP1, CRMP2, CRMP4 and CRMP5 were accompanied by the appearance of distinct 58 kDa (CRMP-2) or 55 kDa (CRMP-4) breakdown products from proteolytic cleavage by calpain. Synaptotagmin breakdown products were also associated with TBI and could be detected along with intact protein in human cerebral spinal fluid (CSF). Both biomarkers were detected in human biofluid and related to recovery from traumatic brain injury. | 02-25-2010 |
20100196942 | BIOMARKERS OF LIVER INJURY - Novel, sensitive and specific markers for diagnostics and monitoring of liver injuries, including, but not limited to ischemic liver damage, are provided. This includes identification several enzymes of arginine/urea/nitric oxide cycle, sulfuration enzymes and spectrin breakdown related products, among others. | 08-05-2010 |
20100317041 | NEURAL PROTEINS AS BIOMARKERS FOR NERVOUS SYSTEM INJURY AND OTHER NEURAL DISORDERS - The present invention identifies biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury. | 12-16-2010 |
20110177974 | NEURAL PROTEINS AS BIOMARKERS FOR NERVOUS SYSTEM INJURY AND OTHER NEURAL DISORDERS - The present invention identities biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury. | 07-21-2011 |
20120196307 | SYNAPTOTAGMIN AND COLLAPSIN RESPONSE MEDIATOR PROTEIN AS BIOMARKERS FOR TRAUMATIC BRAIN INJURY - Collapsin response mediator proteins (CRMPs) decreased in tissue and increased in biological samples after neural injury from traumatic brain injury (TBI). Significant decreases of CRMP1, CRMP2, CRMP4 and CRMP5 were accompanied by the appearance of distinct 58 kDa (CRMP-2) or 55 kDa (CRMP-4) breakdown products from proteolytic cleavage by calpain. Synaptotagmin breakdown products were also associated with TBI and could be detected along with intact protein in human cerebral spinal fluid (biological samples). Both biomarkers were detected in human biofluid and related to recovery from traumatic brain injury. | 08-02-2012 |
20140303041 | IN VITRO DIAGNOSTIC DEVICES FOR NERVOUS SYSTEM INJURY AND OTHER NEURAL DISORDERS - The present invention relates to an exemplary in vitro diagnostic (IVD) device used to detect the presence of and/or severity of neural injuries or neuronal disorders in a subject. The IVD device relies on an immunoassay which identifies biomarkers that are diagnostic of neural injury and/or neuronal disorders in a biological sample, such as whole blood, plasma, serum, cerebrospinal fluid (CSF). The inventive IVD device may measure one or more of several neural specific markers in a biological sample and output the results to a machine readable format wither to a display device or to a storage device internal or external to the IVD. | 10-09-2014 |
Ka-Wang Kevin Wang, Gainsville, FL US
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20090068691 | Endothelial-monocyte activating polypeptide II, a biomarker for use in diagnosis and treatment of brain injury - A diagnostic tool and method of diagnosing brain injury and brain injury type (traumatic vs. ischemic) by detecting the level of expression of endothelial monocyte-activating polypeptide II (EMAP-II) and comparing to a control. An increase of EMAP-II indicates the presence of traumatic brain injury and a decrease of EMAP-II indicates the presence of ischemic brain injury. Detection of EMAP-II can be done in brain tissue, biofluids such as cerebrospinal fluid or blood (including plasma and serum) | 03-12-2009 |
20110028349 | Endothelial monocyte activation polypeptide II, a biomarker for use in diagnosis and treatment of brain injury - A diagnostic tool and method of diagnosing brain injury and brain injury type (traumatic vs. ischemic) by detecting the level of expression of endothelial monocyte-activating polypeptide II (EMAP-II) and comparing to a control. An increase of EMAP-II indicates the presence of traumatic brain injury and a decrease of EMAP-II indicates the presence of ischemic brain injury. Detection of EMAP-II can be done in brain tissue, biofluids such as cerebrospinal fluid or blood (including plasma and serum) | 02-03-2011 |
Kevin Ka-Wang Wang, Gainesville, FL US
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20080311036 | Imaging of Neural and Organ Injury or Damage - In vivo determination of regional damage with neural and organ injury specific imaging agents. Rapid, and non-invasive imaging compositions and methods for assessment of the extent of neurotoxic cell loss or nervous system damage resulting from nervous system injury due to ischemia, stroke, trauma, chemical or electrical insult, acute drug overdose or exposure to substance abuse (such as “recreational drugs”) infection or other insults. The same or similar rapid, and non-invasive imaging compositions and methods for assessment of the extent of the organ injury comprises any damage, injury or infection, functional failure to specific organs such as liver, kidney, prostate, lung, skeletal muscle, heart, pancreas, stomach, small and large intestine, bladder and the reproductive system as well as damage, injury or infection, functional failure to multi-organs, trauma-hemorrhagic shock and sepsis. In particular, neural and organ damage is detected via protease inhibitor-based radionuclide-labeled imaging ligand binding to overactivated proteases (calpains, caspases, cathepsins, proteasome, metalloproteases, granzyme B or other proteases) that are specific to neural or organ injury or damage. | 12-18-2008 |
20090087868 | Neural Proteins as Biomarkers for Nervous System Injury and Other Neural Disorders - The present invention identifies biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury. | 04-02-2009 |
20110082203 | PROCESS TO DIAGNOSE OR TREAT BRAIN INJURY - A process for diagnosing and treating a neurological condition in a subject is provided that includes assaying a biological sample of a subject for the presence of one or more biomarkers; diagnosing a neurological condition based on a ratio of one or more of the biomarkers in the sample; and administering a therapeutic to the subject to alter the ratio of one or more biomarkers. The diagnosis numerous neurological conditions such as brain injury, or multiple organ injury is provided. | 04-07-2011 |
20110097392 | ANTIBODY BOUND SYNTHETIC VESICLE CONTAINING MOLECULES FOR DELIVER TO CENTRAL AND PERIPHERAL NERVOUS SYSTEM CELLS - A process is provided of delivering at least one active agent cargo molecule into an neuronal cell whereby a cargo molecule is placed within a synthetic vesicle such as a liposome and a biotinylated protein such as an antibody is bound to the synthetic vesicle to form a protein bound synthetic vesicle whereby the protein recognizes a receptor expressed on the surface of a neuronal cell, and exposing the protein bound synthetic vesicle to the cell until the cargo molecule is delivered into the neuronal cell. Numerous cargo molecules are delivered by the inventive synthetic vesicle including a calpain inhibitor and a caspase inhibitor. The protein illustratively targets a cellular receptor for a ligand such as glutamate, glycine, dopamine, nicotine, muscarine, acetylcholine, or serotonin, and the like. | 04-28-2011 |
20110143375 | BIOMARKER DETECTION PROCESS AND ASSAY OF NEUROLOGICAL CONDITION - The subject invention provides a robust, quantitative, and reproducible process and assay for diagnosis of a neurological condition in a subject. The invention provides measurement of two or more biomarkers in a biological fluid such as CSF or serum resulting in a synergistic mechanism for determining the extent of neurological damage in a subject with an abnormal neurological condition and for discerning subtypes thereof or tissue types subjected to damage. | 06-16-2011 |
20110191039 | SHOCK WAVE GENERATOR FOR BIOMEDICAL STUDIES - A process of measuring blast shock includes exposing a shock model to an output of a shockwave generator. The propagation of the output is sensed with a sensor platform to generate sensor wave propagation data. The data recorded by the sensor platform is analyzed to measure the blast shock. The blast shock alone or as a component of a cumulative blast exposure can be correlated with an injury metric. A system for measuring cumulative blast shock is provided that includes a sensor platform and an algorithm operating on a microprocessor for analyzing the data recorded by the sensor platform to measure the cumulative blast exposure to injury metrics. | 08-04-2011 |
20110296542 | EXOGENOUS MATRIX-SUPPORTED TOPICAL APPLICATION OF STEM CELLS TO ORGAN SURFACE - A process of tissue regeneration is provided that includes the administration of a stem cell topically to a surface of a tissue. The tissue being in vivo in a subject or in vitro. The tissue has a biocompatible matrix applied around the stem cell and in contact with the surface. After sufficient time, the stem cell infiltrates and regenerates the tissue. A composition is also provided that includes an injured or diseased tissue with a plurality of stem cells proximal to the tissue surface in a biocompatible. A process of increasing a level of cytokines, chemokines, growth factors, anti-apoptotic or anti-necrotic factors in a tissue is provided that includes the administration of a stem cell topically to a surface of a tissue in a biocompatible matrix. After sufficient time, the stem cell releases soluble pro-regenerative factors to increase the levels in the tissue. | 12-01-2011 |
20120202231 | SYNERGISTIC BIOMARKER ASSAY OF NEUROLOGICAL CONDITION USING S-100B - Processes and assays are provided for detecting and determining the magnitude of traumatic brain injury such as that from impact or percussive trauma or stroke. The inventive assays and processes recognize a synergistic correlation between detection of S-IOOb and one or more other injury specific biomarkers. | 08-09-2012 |
20130022982 | MICRO-RNA, AUTOANTIBODY AND PROTEIN MARKERS FOR DIAGNOSIS OF NEURONAL INJURY - Processes and materials are provided for the detection, diagnosis, or determination of the severity of a neurological injury or condition, including traumatic brain injury, multiple-organ injury, stroke, Alzeimer's disease, Pakinson disease and Chronic Traumatic Encephalopathy (CTE). The processes and materials include biomarkers detected or measured in a biological sample such as whole blood, serum, plasma, or CSF. Such biomarkers include Tau and GFAP proteins, their proteolytic breakdown products, brain specific or enriched micro-RNA, and brain specific or enriched protein directed autoantibodies. The processes and materials are operable to detect the presence of absence of acute, subacute or chronic brain injuries and predict outcome for the brain injury. | 01-24-2013 |
20130029362 | MARKERS AND ASSAYS FOR DETECTION OF NEUROTOXICITY - A process and assay for diagnosing neurotoxicity in a subject is provided. The extent of a neurotoxic insult to a subject is assessed through the measurement of one or more biomarkers in a biological fluid, such as CSF or serum. Other uses and advantages afforded include pre-market drug discovery, monitoring, drug neurotoxicity screening and post market assessment of safety and monitoring for drug of known potential neurotoxicity. | 01-31-2013 |
20130029859 | BIOMARKER ASSAY OF NEUROLOGICAL CONDITION - A process and assay for determining the neurological condition in a subject is provided whereby the level of one or more neuroactive biomarkers is measured in a sample obtained from the subject. The processes and assay include measurement of multiple neuroactive biomarkers for synergistic determination of a neurological condition such as neurological damage due to injury, disease, contact with a compound, or other source. | 01-31-2013 |
20140024053 | METHODS, KITS AND DEVICES FOR DETECTING BII-SPECTRIN, AND BREAKDOWN PRODUCTS THEREOF, AS BIOMARKERS FOR THE DIAGNOSIS OF NEURAL INJURY - The present invention identifies biomarkers that are diagnostic of neural injury, neuronal disorder or neurotoxicity and is related to the discovery that proteases are selectively activated in subjects suffering from nervous system damage as compared to healthy subjects. Breakdown products reflecting protease activation are produced and detection of these different biomarkers of the invention is also diagnostic of the degree of severity and type of nerve damage in a subject. | 01-23-2014 |
20140178351 | COMPOSITIONS AND METHODS RELATING TO ARGININOSUCCCINATE SYNTHETASE - Processes and compositions for the therapeutic treatment of pathogenic Gram-negative bacterial infection are provided whereby arginino succinate synthetase or PEGylated arginino succinate synthetase is administered to a subject to inactivate endotoxin thereby reducing the likelihood of bacterial sepsis and improving patient outcome. | 06-26-2014 |
20150268252 | BIOMARKER ASSAY OF NEUROLOGICAL CONDITION - A robust, quantitative, and reproducible process and assay for diagnosis of a neurological condition in a subject is provided. With measurement of one or more autoantibodies to biomarkers in a biological fluid such as CSF or serum, the extent of neurological damage in a subject with an abnormal neurological condition is determined and subtypes thereof or tissue types subjected to damage are discerned. | 09-24-2015 |
Kevin K.w. Wang, Gainesville, FL US
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20080204043 | Real-Time Assessment of Biomarkers for Disease - A system and methods, thereof, monitor biomarkers from a patient suffering from neural injury in real-time. The system comprises a quartz crystal microbalance wherein a capture molecule specific for certain biomarkers is diagnostic of the type of neural injury, location of neural injury and the degree of severity of neural injury. The system, in particular, provides real-time continuous monitoring of a patient. | 08-28-2008 |
Kui Wang, Fort Myers, FL US
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20140178958 | Cyanobacterium sp. for Production of Compounds - A genetically enhanced cyanobacterial host cell, | 06-26-2014 |
20140178973 | Cyanobacterium sp. Host Cell and Vector for Production of Chemical Compounds in Cyanobacterial Cultures - A cyanobacterial host cell, | 06-26-2014 |
20150322442 | Novel Shuttle Vector Capable of Transforming Multiple Genera of Cyanobacteria - A plasmid vector for the production of compounds in cyanobacteria is described which is capable of being efficiently transformed to and replicating in a broad range of cyanobacterial species. | 11-12-2015 |
Michael Wang, Miami, FL US
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20090062857 | Minimally invasive guide system - A minimally invasive fixation system and installation method is provided. The system includes a rod having an anchor fixation head, an anchor system for anchoring the rod using the anchor fixation head, and a guide system configured to attach to the anchor fixation head of the rod for the insertion of the additional anchor systems. In one embodiment, a method for placing a spinal fixation element relative to a vertebra is provided. The method includes inserting the spinal fixation element relative to the vertebra; connecting the spinal fixation element to a first vertebra with a first anchor; manipulating the spinal fixation element relative to the first anchor to align the spinal fixation element with a second vertebra; fixing the position of the spinal fixation element relative to the first bone anchor; determining an anchor site on a second vertebra using a guide system connected to the spinal fixation element; inserting a second anchor at an anchor site on second vertebra; and connecting the second anchor to the spinal fixation element to fix the spinal fixation element relative to the first vertebra and second vertebra. | 03-05-2009 |
20090062859 | Method and system for securing a rod to a bone anchor with a connector - A rod anchoring system including a bone anchor and a connector is provided. The connector of the rod anchoring system is configured to be inserted in one orientation and then transitioned to a second orientation to connect the rod to the anchor. The bone anchor includes a detachable extension shaft that acts a guide for inserting the connector. In use, once the bone anchor has been implanted at a target site on a vertebra, the connector is placed onto the extension shaft and slid along its length in a first orientation to insert the connector. Once the connector is at the implant site, it is transitioned from the first orientation to the second orientation to connect the rod to the anchor. | 03-05-2009 |
20140031939 | MESH SPACER HYBRID - A modular implant for performing an intervertebral fusion on adjacent vertebral bodies in a patient including a first spacer portion, a second spacer and a container having a first end and a second end, the first end of the container constructed to operably engage a first spacer and the second end of the container constructed to operably engage the second spacer. | 01-30-2014 |
Michael Renxun Wang, Miami, FL US
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20130169933 | Tear Film and Contact Lens Evaluation by Optical Reflectometry Technique - A method and system for evaluation tear film thickness and thinning dynamics in an eye with or without wearing a contact lens using a specially configured optical reflectometer. The method and system may address the beam aiming flexibility on the tear film surface by incorporation of a galvanometer scanner with the fiber coupled optical reflectometer. The tear film thickness, tear film thinning dynamics, and tear film breakup thickness can be determined. The system can also be combined with spectral domain OCT or swept source OCT for ophthalmology applications. The advantage is fast and high precision tear film evaluation that can also be extended to water film on contact lens evaluation for the determination of contact lens hydrophilic properties. | 07-04-2013 |
Michael Y. Wang, North Miami, FL US
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20150185232 | INNATE IMMUNE PROTEINS AS BIOMARKERS FOR CNS INJURY - The present invention provides novel markers of the severity of a central nervous system injury, such as spinal cord injury or traumatic brain injury, in a patient. In particular, protein components of inflammasomes in the cerebrospinal fluid that can be used to assess the severity of central nervous system injury in a patient are disclosed. Methods of using such protein biomarkers to determine a prognosis, direct treatment and rehabilitation efforts, and monitor response to treatment for a patient with a central nervous system injury are also described. | 07-02-2015 |
Nian Wang, Auburndale, FL US
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20160021882 | APPLICATION OF BIOFILM FORMATION INHIBITING COMPOUNDS ENHANCES CONTROL OF CITRUS CANKER - Citrus canker caused by the bacterium | 01-28-2016 |
Nian Wang, Lake Alfred, FL US
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20150087512 | ANTIMICROBIAL COMPOUNDS AND THEIR USE IN TREATING PLANT DISEASE - The subject invention is directed toward antimicrobial agents and methods of treating and preventing infection by pathogenic microorganisms and endophytic microorganisms in a plant through the use of SecA inhibitors. | 03-26-2015 |
Qifeng Wang, Tallahassee, FL US
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20150104484 | STORED STRAIN POLYELECTROLYTE COMPLEXES AND METHODS OF FORMING - The present disclosure is directed to articles comprising a polyelectrolyte complex which stores mechanical strain and methods of forming articles comprising a polyelectrolyte complex which stores mechanical strain. | 04-16-2015 |
Qingzhao Wang, Gainesville, FL US
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20120129231 | ENGINEERING OF THERMOTOLERANT BACILLUS COAGULANS FOR PRODUCTION OF D(-)-LACTIC ACID - Genetically modified microorganisms having the ability to produce D(−)-lactic acid at temperatures between 30° C. and 55° C. are provided. In various embodiments, the microorganisms may have the chromosomal lactate dehydrogenase (ldh) gene and/or the chromosomal acetolactate synthase (alsS) gene inactivated. Exemplary microorganisms for use in the disclosed methods are | 05-24-2012 |
Quincy Q. Wang, West Palm Beach, FL US
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20080197705 | System including a microturbine and a high-frequency alternator generating backup power for a telecommunications system - A system includes an electrical load formed by a number of circuits within a system performing telecommunication functions, primary and backup sources of electrical power, and a relay that switches an input to the electrical load from the primary source to the backup source in response to determining that a failure has occurred within the primary source. The backup source includes a microturbine driving a six-phase, high-frequency alternator, which is turned on in response to determining that such a failure has occurred, and, preferably, a battery array that provides backup power when adequate power is not available from the alternator driven by the microturbine. | 08-21-2008 |
Quincy Qing Wang, Wellington, FL US
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20150315935 | SYSTEM AND METHOD FOR INDUCTOR COOLING - A system includes a cooling system. The cooling system includes a Rankine cycle and an inductor coupled to the cooling system. The inductor generates heat when in operation. The Rankine cycle circulates a working fluid when in operation, and the working fluid is configured to cool the inductor and to facilitate absorbing heat generated by the inductor. | 11-05-2015 |
Ru T. Wang, Gainesville, FL US
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20090038213 | PRE-BURNING, DRY PROCESS METHODOLOGY AND SYSTEMS FOR ENHANCING METALLURGICAL SOLID FUEL PROPERTIES - Measurements are taken of moisture, BTU/lb (British Thermal Units per pound), ash, forms of sulfur, volatile material, grindability, and absorption properties of any of a wide variety of mine-run solid fuels. Using that information, a dry electromagnetic process technology has been developed that can be controlled and monitored to selectively alter and enhance metallurgical solid fuel properties. Specific changes include altering the mechanical structure and chemical composition of solid fuels such as coal, coal coke or petroleum coke, increasing the BTU/lb to optimum levels, decreasing all forms of sulfur, and decreasing ash, while maintaining the BTU/lb of the fuels. A new family of solid fuel designer coals not found in nature can be produced via these methods and apparatus. | 02-12-2009 |
20140070116 | PRE-BURNING, DRY PROCESS METHODOLOGY AND SYSTEMS FOR ENHANCING METTALLURGICAL SOLID FUEL PROPERTIES - Measurements are taken of moisture, BTU/lb (British Thermal Units per pound), ash, forms of sulfur, volatile material, grindability, and absorption properties of any of a wide variety of mine-run solid fuels. Using that information, a dry electromagnetic process technology has been developed that can be controlled and monitored to selectively alter and enhance metallurgical solid fuel properties. Specific changes include altering the mechanical structure and chemical composition of solid fuels such as coal, coal coke or petroleum coke, increasing the BTU/lb to optimum levels, decreasing all forms of sulfur, and decreasing ash, while maintaining the BTU/lb of the fuels. A new family of solid fuel designer coals not found in nature can be produced via these methods and apparatus. | 03-13-2014 |
Sheng-Ming Wang, Tarpon Springs,, FL US
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20090090138 | Air jet pressurized clothes washing machine - A washing machine having high pressure angled air jets that introduce air into the wash water in a stationary pressurized tub. A circular swirl flow-pattern and air pressure within the warm wash water agitates and cleans the clothes without the need for a mechanically rotated drum or detergent. Sediment from the laundry is removed from the water by drains both at the top and the bottom of the tub. At the end of the wash cycle, the high pressure air is used to drain and dehydrate the clean clothes. | 04-09-2009 |
20120168400 | Capped beverage container having an open chamber storing a sealed tube of other beverage - A beverage container made of plastic by blow molding process has three chambers all along a same axis—an upper conical chamber with a removable cap to contain carbon dioxide gas (but not limited to), a lower outer cylindrical chamber, connected to the upper conical chamber, to contain a carbonated drink (but not limited to), and an inner cylindrical open chamber, smaller in diameter & height than the lower outer cylindrical chamber and isolated from the two other chambers, to store a sealed cylindrical tube containing a pasteurized drink (but not limited to). A liquid ratio of the carbonated drink to the pasteurized drink is the ratio of an optimum mixture of the two beverages into a certain desired cocktail punch. | 07-05-2012 |
20150048002 | Two Nested and Interlocked Beverage Containers - The present invention discloses a beverage container | 02-19-2015 |
Shiren Wang, Tallahassee, FL US
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20100028639 | Method for Functionalization of Nanoscale Fiber Films - Methods are provided for functionalizing a macroscopic film comprised of nanoscale fibers by controlled irradiation. The methods may include the steps of (a) providing a nanoscale fiber film material comprising a plurality of nanoscale fibers (which may include single wall nanotubes, multi-wall nanotubes, carbon nanofibers, or a combination thereof); and (b) irradiating the nanoscale fiber film material with a controlled amount of radiation in the open air or in a controlled atmosphere. The step of irradiating the nanoscale fiber film material is effective to functionalize the plurality of nanoscale fibers. Irradiated nanoscale fiber films are also provided having improved mechanical and electrical conducting properties. | 02-04-2010 |
Tiansi Wang, Orlando, FL US
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20150338718 | ACOUSTO-OPTIC DEFLECTOR WITH MULTIPLE TRANSDUCERS FOR OPTICAL BEAM STEERING - An acousto-optic deflector with multiple acoustic transducers is described that is suitable for use in substrate processing. In one example a method includes transmitting an optic beam through an acousto-optic deflector, applying an acoustic signal with a phase delay across multiple transducers of the acousto-optic deflector to deflect the beam along a first axis by the acousto-optic deflector, and directing the deflected beam onto a workpiece. | 11-26-2015 |
Tie Wang, Gainesville, FL US
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20140319563 | LATERALLY ALIGNED COLLOIDAL NANORODS ASSEMBLIES - Nanorods assemblies that have lengths in excess of 50 microns to meters are formed from contacting rice-shaped colloidal superparticles that are aligned along the long axis of the colloidal superparticles. The rice-shaped colloidal superparticles are formed from a multiplicity of nanorods with a high degree of association that is end to end to form colloidal superparticles that are in excess of three microns in length and have a length to diameter ratio of about three or more. Methods of preparing the rice-shaped colloidal superparticles employ mixing with an additional ligand to the nanorods to bias the self assembly of the nanorods by solvophobic interactions. Methods of preparing the nanorods assemblies include the infusion of the rice-shaped colloidal superparticles into microchannels patterned on a substrate, wherein the rice-shaped colloidal superparticles' long axes align in the microchannels. | 10-30-2014 |
Weidong Wang, Oldsmar, FL US
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20100180953 | Thermally Induced Single-Use Valves and Method of Use - In accordance with an embodiment of the present invention, a thermally induced single-use valve is provided including a silicon wafer having a top surface and a bottom surface and at least one cavity formed in the bottom surface of the wafer, a thermally deformable membrane suspended across the cavity on the top surface of the wafer and at least one resistive element patterned on top of the thermally deformable membrane. | 07-22-2010 |
Weixun Wang, Gainesville, FL US
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20100223237 | LOSSLESS DATA COMPRESSION AND REAL-TIME DECOMPRESSION - A method, information processing system, and computer program storage product store data in an information processing system. Uncompressed data is received and the uncompressed data is divided into a series of vectors. A sequence of profitable bitmask patterns is identified for the vectors that maximizes compression efficiency while minimizes decompression penalty. Matching patterns are created using multiple bit masks based on a set of maximum values of the frequency distribution of the vectors. A dictionary is built based upon the set of maximum values in the frequency distribution and a bit mask savings which is a number of bits reduced using each of the multiple bit masks. Each of the vectors is compressed using the dictionary and the matching patterns with having high bit mask savings. The compressed vectors are stored into memory. Also, an efficient placement is developed to enable parallel decompression of the compressed codes. | 09-02-2010 |
Wenbiao Wang, Tampa, FL US
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20130163822 | Airborne Image Capture and Recognition System - Provided is a system and method of electronically identifying a license plate and comparing the results to a predetermined database. The software aspect of the system runs on standard PC hardware and can be linked to other applications or databases. It first uses a series of image manipulation techniques to detect, normalize and enhance the image of the number plate. Optical character recognition (OCR) is used to extract the alpha-numeric characters of the license plate. The recognized characters are then compared to databases containing information about the vehicle and/or owner. | 06-27-2013 |
20130163823 | Image Capture and Recognition System Having Real-Time Secure Communication - Provided is a system and method of electronically identifying a license plate and comparing the results to a predetermined database. The software aspect of the system runs on standard PC hardware and can be linked to other applications or databases. It first uses a series of image manipulation techniques to detect, normalize and enhance the image of the number plate. Optical character recognition (OCR) is used to extract the alpha-numeric characters of the license plate. The recognized characters are then compared to databases containing information about the vehicle and/or owner. | 06-27-2013 |
20140369566 | Perimeter Image Capture and Recognition System - Provided is a system and method of electronically identifying a vehicle entering/leaving a predetermined geographical area by identifying a license plate and comparing the results to a predetermined database. The software aspect of the system runs on standard PC hardware and can be linked to other applications or databases. It first uses a series of image manipulation techniques to detect, normalize and enhance the image of the number plate. Optical character recognition (OCR) is used to extract the alpha-numeric characters of the license plate. The recognized characters are then compared to databases containing information about the vehicle and/or owner. | 12-18-2014 |
20140369567 | Authorized Access Using Image Capture and Recognition System - Provided is a system and method of electronically identifying a vehicle entering/leaving a predetermined geographical area by identifying a license plate and comparing the results to a predetermined database. The software aspect of the system runs on standard PC hardware and can be linked to other applications or databases. It first uses a series of image manipulation techniques to detect, normalize and enhance the image of the number plate. Optical character recognition (OCR) is used to extract the alpha-numeric characters of the license plate. The recognized characters are then compared to databases containing information about the vehicle and/or owner. | 12-18-2014 |
Wenshi Wang, Tampa, FL US
Patent application number | Description | Published |
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20150118245 | Predictive Biomarkers for CTLA-4 Blockade Therapy and for PD-1 Blockade Therapy - Biomarkers are described for predicting the efficacy, risk of relapse, risk of an immune related adverse event (irAE), or combination thereof for a CTLA-4 blockade treatment, such as ipilimumab, in a subject with melanoma. Biomarkers are also described for predicting the efficacy and clinical benefit for a PD-1 blockade treatment, such as a PD-1 blocking antibody, in a subject with melanoma. | 04-30-2015 |
Wentao Wang, Tallahassee, FL US
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20150284493 | PHOTOLIGATION OF AN AMPHIPHILIC POLYMER WITH MIXED COORDINATION PROVIDES COMPACT AND REACTIVE QUANTUM DOTS - The disclosure is directed to multi-coordinating polymers as ligands that combine two distinct metal-chelating groups, lipoic acid and imidazole, for the surface functionalization of QDs. These ligands combine the benefits of thiol and imidazole coordination to reduce issues of thiol oxidation and weak binding affinity of imidazole. The ligand design relies on the introduction of controllable numbers of lipoic acid and histamine anchors, along with hydrophilic moieties and reactive functionalities, onto a poly(isobutylene-alt-maleic anhydride) chain via a one-step nucleophilic addition reaction. We further demonstrate that this design is fully compatible with a novel and mild photoligation strategy to promote the in-situ ligand exchange and phase transfer of hydrophobic QDs to aqueous media under borohydride-free conditions. Ligation with these polymers provides highly fluorescent QDs that exhibit great long-term colloidal stability over a wide range of conditions. | 10-08-2015 |
20150284517 | POLYMER LIGANDS FOR NANOPARTICLES - The disclosure is directed to polymer ligands that are optimally suited for surface-functionalizing magnetic nanoparticles. The amphiphilic polymers are prepared by coupling several amine-terminated anchoring groups, polyethylene glycol moieties, and reactive groups onto a poly(isobutylene-alt-maleic anhydride) (PIMA) chain. The reaction of maleic anhydride groups with amine-containing molecules is highly-efficient and occurs in one-step. The availability of several dopamine groups in the same ligand greatly enhances the ligand affinity, via multiple-coordination, to the magnetic NPs, while the hydrophilic and reactive groups promote colloidal stability in buffer media and allow subsequent conjugation with target biomolecules. Nanoparticles ligated with terminally reactive polymers have been easily coupled to target dyes and tested in live cell imaging with no measurable cytotoxicity. | 10-08-2015 |
Xiaoqin Wang, Tampa, FL US
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20080214437 | Methods and compositions for reducing activity of the atrial natriuretic peptide receptor and for treatment of diseases - Methods, compositions and devices are provided by the present invention for reducing activity of a natriuretic peptide receptor and other signals. Therapeutic treatments are provided by use of polynucleotides encoding a natriuretic peptide or by regulating the expression of natriuretic peptide receptor, such as NPRA and NPRC, or combinations of these therapies. Routes used for delivering polynucleotides encoding a natriuretic peptide, or, for example, siRNA that down regulates natriuretic peptide receptor include subcutaneous injection, oral gavage, transdermal and intranasal delivery routes. Compositions can include chitosan, chitosan derivatives, and chitosan derivative and a lipid. Transdermal delivery can use a transdermal cream. Intranasal delivery can use a dropper or an aspirator for delivery of a mist. Oral gavage delivers equivalent to oral delivery. Delivery permits cell and tissue specific targeting of gene therapies resulting in expression of a natriuretic peptide or down regulation of natriuretic peptide receptor. A variety of cancers, asthma and viral diseases can be treated therapeutically using the methods and compositions of the present invention. | 09-04-2008 |
Xirui Wang, Gainesville, FL US
Patent application number | Description | Published |
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20140319563 | LATERALLY ALIGNED COLLOIDAL NANORODS ASSEMBLIES - Nanorods assemblies that have lengths in excess of 50 microns to meters are formed from contacting rice-shaped colloidal superparticles that are aligned along the long axis of the colloidal superparticles. The rice-shaped colloidal superparticles are formed from a multiplicity of nanorods with a high degree of association that is end to end to form colloidal superparticles that are in excess of three microns in length and have a length to diameter ratio of about three or more. Methods of preparing the rice-shaped colloidal superparticles employ mixing with an additional ligand to the nanorods to bias the self assembly of the nanorods by solvophobic interactions. Methods of preparing the nanorods assemblies include the infusion of the rice-shaped colloidal superparticles into microchannels patterned on a substrate, wherein the rice-shaped colloidal superparticles' long axes align in the microchannels. | 10-30-2014 |
Xisen Wang, Tampa, FL US
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20140107333 | POLYHEDRAL CAGE-CONTAINING METALLOPORPHYRIN FRAMEWORKS, METHODS OF MAKING, AND METHODS OF USING - Embodiments of the present disclosure provide compositions including metal-organic polyhedrons, metalloporphyrin framework structures, methods of making these, methods of using these, and the like. | 04-17-2014 |
Yanchang Wang, Tallahassee, FL US
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20100016247 | USING BUDDING YEAST TO SCREEN FOR INHIBITORS OF AURORA KINASES - Methods of screening for novel Aurora kinase inhibitors in higher organisms are provided using hypomorphic ipl1 mutant yeast cells. Putative Aurora kinase inhibitors identified by present screening methods may be useful in treating individuals having a proliferative disease, such as cancer. Chemical compounds identified by present methods as selectively inhibiting growth of hypomorphic ipl1 mutant yeast cells may be used in compositions. Compositions or compounds identified by such screening methods may be administered to an individual in need thereof. | 01-21-2010 |
Yiwen Wang, Gainesville, FL US
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20080285829 | System and Method for Consistent Detection of Mid-Sagittal Planes for Magnetic Resonance Brain Scans - A method for finding consistent mid-sagittal planes (MSPs) in a pair of 3D image head scans of a same patient includes, for each image, selecting a 2D transverse localizer image from a middle slice along a transverse view of the 3D image, fitting an ellipse to the transverse localizer image to locate a head position (x, y), where the y-coordinate is indicative of a position of a 2D coronal localizer image in the 3D image, fitting an ellipse to the coronal localizer image to locate a head position (x, y) in the coronal localizer image, calculating a middle line in the transverse localizer image and a middle line in the coronal localizer image, calculating an MSP from the middle lines, and determining a new set of slope and intercept parameters for one MSP that maximizes a similarity measure between the one MSP and the other MSP. | 11-20-2008 |
Yongping Wang, Sarasota, FL US
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20150378180 | EYEWEAR DOCKING STATION AND ELECTRONIC MODULE - An eyewear system including an eyewear frame and an application module. The eyewear frame including a docking station, and an electronic connector including a first set of preconfigured application connection points. The application module adapted to be mounted to the docking station, and including an electronic device configured to perform a function, and a second set of preconfigured application connection points corresponding to at least some of the first set of preconfigured application connection points. The second set of preconfigured application connection points including at least two different sub-function connections used to support the function of the electronic device. | 12-31-2015 |
Zhixin Wang, Winter Park, FL US
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20150236011 | DIRECT CONNECTED SILICON CONTROLLED RECTIFIER (SCR) HAVING INTERNAL TRIGGER - In one aspect, a direct connected silicon control rectifier (DCSCR) includes a substrate having a semiconductor surface, a parasitic PNP bipolar transistor and a parasitic NPN bipolar transistor formed in the semiconductor surface. The parasitic PNP bipolar transistor includes a p+ emitter, an nbase and a pcollector and the parasitic NPN bipolar includes an n+ emitter, a pbase and an ncollector. The DCSCR also includes an electrically conductive line connecting an n+ contact to the nbase to a p+ contact to the pbase so that the nbase and the pbase are shorted. | 08-20-2015 |
Zhongliang Wang, Gainesville, FL US
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20130034532 | NANOZYMES, METHODS OF MAKING NANOZYMES, AND METHODS OF USING NANOZYMES - Embodiments of the present disclosure provides for nanozymes, methods of making nanozymes, methods of using nanozymes, and the like. | 02-07-2013 |