Patent application number | Description | Published |
20090117601 | METHODS AND COMPOSITIONS FOR THE DETECTION OF BETA-LACTAMASES - Presented herein are methods and compositions for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases. AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes. | 05-07-2009 |
20090142796 | Detection of Inducible Resistance to Macrolide-Lincosamide-Streptogramin b - The embodiments of this invention provide a test panel and method for the detection of inducible resistance to macrolide-lincosamide-streptogramin b (iMLSb) in microorganisms in an automated microorganism identification (ID) and antimicrobial susceptibility determinations (AST) system. | 06-04-2009 |
20100016276 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF A CARBAPENEMASE GENE - Compositions and methods for the rapid and sensitive detection of a carbapenemase in a sample is provided. The compositions include novel primer and probe compositions for use in detecting the presence of this enzyme in a sample, particularly using PCR methods. These primers and probe sets can be used in amplification methods (such as PCR, particularly quantitative PCR) and packaged into kits for use in amplification methods for the purpose of detecting carbapenemase in a test sample, particularly a patient sample, particularly a direct sample. Thus, in one embodiment, the present invention provides for novel oligonucleotide primers set forth in SEQ ID NOs:1, 2, 4, 5, 7, 8, 14, 15, 17, 18, and 20, and the novel oligonucleotide probe sequences set forth in SEQ ID NOs:3, 6, 9, 16, and 19. These sequences can be used in a method of detecting carbapenemase in a sample. | 01-21-2010 |
20110262957 | COMPOSITIONS FOR THE DETECTION OF INTRACELLULAR BACTERIAL TARGETS AND OTHER INTRACELLULAR MICORORGANISM TARGETS - Presented herein are solid supports on or in which a composition comprising a lysis reagent and an intracellular microorganism target detection reagent (e.g., an intracellular bacterial target detection reagent) is present in added form. Presented herein are also methods for detecting the presence of an intracellular microorganism target (e.g., an intracellular bacterial target) utilizing such solid supports. Further, presented herein are tablets as well as dry powders comprising a lysis reagent and an intracellular microorganism target detection reagent (e.g., an intracellular bacterial target detection reagent), and methods of using such tablets and dry powders to detect the presence of an intracellular microorganism target (e.g., an intracellular bacterial target). | 10-27-2011 |
20120071642 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF A CARBAPENEMASE GENE - Compositions and methods for the rapid and sensitive detection of a carbapenemase in a sample are provided. The compositions include novel primer and probe compositions for use in detecting the presence of this enzyme in a sample, particularly using PCR methods. These primers and probe sets can be used in amplification methods (such as PCR, particularly quantitative PCR) and packaged into kits for use in amplification methods for the purpose of detecting carbapenemase in a test sample, particularly a patient sample, particularly a direct sample. Thus, in one embodiment, the present invention provides for novel oligonucleotide primers set forth in SEQ ID NOs:1, 2, 4, 5, 7, 8, 14, 15, 17, 18, and 20, and the novel oligonucleotide probe sequences set forth in SEQ ID NOs:3, 6, 9, 16, and 19. These sequences can be used in a method of detecting carbapenemase in a sample. | 03-22-2012 |
20120077215 | METHODS AND COMPOSITIONS FOR THE DETECTION OF BETA-LACTAMASES - Presented herein are methods and compositions for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes. | 03-29-2012 |
20140080164 | METHODS AND COMPOSITIONS FOR THE DETECTION OF BETA-LACTAMASES - Presented herein are methods and compositions for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes. | 03-20-2014 |
Patent application number | Description | Published |
20130172309 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF A CARBAPANEMASE GENE - Compositions and methods for the rapid and sensitive detection of a carbapenemase in a sample are provided. The compositions include novel primer and probe compositions for use in detecting the presence of this enzyme in a sample, particularly using PCR methods. These primers and probe sets can be used in amplification methods (such as PCR, particularly quantitative PCR) and packaged into kits for use in amplification methods for the purpose of detecting carbapenemase in a test sample, particularly a patient sample, particularly a direct sample. Thus, in one embodiment, the present invention provides for novel oligonucleotide primers set forth in SEQ ID NOs:1, 2, 4, 5, 7, 8, 14, 15, 17, 18, and 20, and the novel oligonucleotide probe sequences set forth in SEQ ID NOs:3, 6, 9, 16, and 19. These sequences can be used in a method of detecting carbapenemase in a sample. | 07-04-2013 |
Patent application number | Description | Published |
20080287342 | Compositions Comprising Modified Collagen and Uses Therefor - The invention provides modified collagen and related therapeutic and diagnostic methods. | 11-20-2008 |
20100230629 | PIEZOELECTRIC COMPOSITIONS - Piezoelectric compositions are provided wherein mechanical and piezoelectric properties can be separately modulated. Preferred compositions include resin blends that comprise: (a) a piezoelectrically active polymer and (b) a matrix polymer, methods of making, and use of such resin blends. Advantages of preferred resin blends of the invention can include high piezoelectricity, mechanical strength and flexibility, convenient fabrication process, and high sensitivity at high temperatures. | 09-16-2010 |
20110260584 | PIEZOELECTRIC POLYMER FIBERS - Piezoelectric fibers include a polypeptide wherein molecules of the polypeptide have electric dipole moments that are aligned such that the piezoelectric fiber provides a piezoelectric effect at an operating temperature. A piezoelectric component provides a plurality of piezoelectric fibers, each comprising an organic polymer. A method of producing piezoelectric fibers includes electrospinning a polymer solution to form a fiber and winding the fiber onto a rotating target in which the rotating target is electrically grounded. An acoustic sensor includes a plurality acoustic transducers, wherein the plurality of acoustic transducers are structured and arranged to detect a corresponding plurality of vector components of an acoustic signal, and at least one of the plurality of acoustic transducers comprises a piezoelectric fiber. | 10-27-2011 |
20130116405 | COMPOSITIONS COMPRISING MODIFIED COLLAGEN AND USES THEREFOR - The invention provides modified collagen and related therapeutic and diagnostic methods. | 05-09-2013 |
20130229091 | CONTINUOUS PIEZOELECTRIC FILM INCLUDING POLAR POLYMER FIBERS - A continuous piezoelectric film can include a plurality of fibers, each fiber including a polypeptide, wherein molecules of the polypeptide have electric dipole moments that are aligned such that the piezoelectric fiber provides a piezoelectric effect. The continuous piezoelectric film has at least one piezoelectric constant d | 09-05-2013 |
20140117272 | PIEZOELECTRIC COMPOSITIONS - Piezoelectric compositions are provided wherein mechanical and piezoelectric properties can be separately modulated. Preferred compositions include resin blends that comprise: (a) a piezoelectrically active polymer and (b) a matrix polymer, methods of making, and use of such resin blends. Advantages of preferred resin blends of the invention can include high piezoelectricity, mechanical strength and flexibility, convenient fabrication process, and high sensitivity at high temperatures. | 05-01-2014 |
20150111308 | COMPOSITIONS COMPRISING MODIFIED COLLAGEN AND USES THEREFOR - The invention provides modified collagen and related therapeutic and diagnostic methods. | 04-23-2015 |
20150215707 | PBLG BASED PLANAR MICROPHONES - A piezoelectric, poly (γ-benzyl-α,L-glutamate) (“PBLG”) planar microphone, and method for construction thereof, are disclosed. The microphone includes at least a polyester film, a piezoelectric, hot pressed poly (γ-benzyl-α,L-glutamate) (“HPPBLG”) layer, and an aluminum coating for the HPPBLG layer. The coated HPPBLG layer is coupled to the polyester film. | 07-30-2015 |
Patent application number | Description | Published |
20100246825 | WIRELESS COMMUNICATION METHOD AND SYSTEM FOR TRANSMISSION AUTHENTICATION AT THE PHYSICAL LAYER - The subject authentication scheme encompasses a large family of authentication systems which may be built over existing transmission systems. By superimposing a carefully designed secret modulation on the waveforms, authentication is added to the signal without requiring additional bandwidth. The authentication information (tag signal) is sent concurrently with data (message signal). The authentication is designed to be stealthy to the uninformed user, robust to interference, and secure for identity verification. The tradeoffs between these three goals are identified and analyzed. The use of the authentication for channel estimation is also considered, and improved bit errors are demonstrated for time-varying channels. With a long enough authentication code word an authentication system is achieved with very slight data degradation. Additionally, by treating the authentication tag as a sequence of pilot symbols, the data recovery may be improved by the aware receiver. | 09-30-2010 |
20100272256 | Method and Implementation for Information Exchange Using Markov Models - The replacement of secret keys is a central problem in key management. Typical solutions exchange handshaking messages, involve complex computations, or require the cooperation of trusted third parties. Disclosed herein is a key replacement method that exploits the randomness of Markov models to efficiently provide fresh keys to users. Unlike other methods, the proposed method removes the need for extra communications, intensive computation, or third parties. It is demonstrated that the proposed method has perfect forward secrecy as well as resistance to known-key attacks. | 10-28-2010 |
20130163761 | WIRELESS COMMUNICATION METHOD AND SYSTEM FOR TRANSMISSION AUTHENTICATION AT THE PHYSICAL LAYER - The subject authentication scheme encompasses a large family of authentication systems which may be built over existing transmission systems. By superimposing a carefully designed secret modulation on the waveforms, authentication is added to the signal without requiring additional bandwidth. The authentication information (tag signal) is sent concurrently with data (message signal). The authentication is designed to be stealthy to the uninformed user, robust to interference, and secure for identity verification. The tradeoffs between these three goals are identified and analyzed. The use of the authentication for channel estimation is also considered, and improved bit errors are demonstrated for time-varying channels. With a long enough authentication code word an authentication system is achieved with very slight data degradation. Additionally, by treating the authentication tag as a sequence of pilot symbols, the data recovery may be improved by the aware receiver. | 06-27-2013 |
Patent application number | Description | Published |
20080319032 | TETRAHYDROBENZOTHIAZOLE ANALOGUES AS NEUROPROTECTIVE AGENTS - This invention relates generally to tetrahydrobenzothiazole analogues and tetrahydrobenzooxyzole analogues, to pharmaceutical compositions which include these compounds and a pharmaceutically acceptable carrier, and to methods of treatment using these compounds. The invention also encompasses pharmaceutically acceptable esters, amides, and salts of such compounds. The invention further provides a method of reducing or delaying apoptosis in a population of cells, comprising contacting the population of cells with a tetrahydrobenzothiazole analogue or a tetrahydrobenzooxyzole analogue, thereby reducing or delaying apoptosis in the population of cells. | 12-25-2008 |
20100105707 | METHOD OF TREATING OR PREVENTING OXIDATIVE STRESS-RELATED DISEASE - Disclosed is a method of treating or preventing an oxidative stress-related disease in a mammal in need thereof comprising administering an effective amount of a compound of formula (I) to the mammal, wherein R | 04-29-2010 |
20110245210 | THALIDOMIDE ANALOGS - Thalidomide analogs that modulate tumor necrosis factor alpha (TNF-α) activity and angiogenesis are disclosed. In particularly disclosed embodiments, the thalidomide analogs are isosteric sulfur-containing analogs. Also disclosed are methods of treating a subject with the analogs. | 10-06-2011 |
20130035363 | Thalidomide Analogs - Thalidomide analogs that modulate tumor necrosis factor alpha (TNFα) activity and angiogenesis are disclosed. In particularly disclosed embodiments, the thalidomide analogs are isosteric sulfur-containing analogs. Also disclosed are methods of treating a subject with the analogs. | 02-07-2013 |
20130143922 | THIO COMPOUNDS - A compound, or a pharmaceutically acceptable salt or ester thereof, having a structure of: | 06-06-2013 |
20140309436 | THALIDOMIDE ANALOGS - Thalidomide analogs that modulate tumor necrosis factor alpha (TNFα) activity and angiogenesis are disclosed. In particularly disclosed embodiments, the thalidomide analogs are isosteric sulfur-containing analogs. Also disclosed are methods of treating a subject with the analogs. | 10-16-2014 |
Patent application number | Description | Published |
20130325754 | Residential Housing Complex - A residential housing complex that includes a school. The school (e.g. primary and/or secondary school) uses a machine-guided teaching curriculum. For example, the school can implement a blended learning curriculum. The residential housing complex may be located in urban areas to provide better schools for families with children. | 12-05-2013 |
20140322693 | Student-to-Student Assistance in a Blended Learning Curriculum - A method of providing primary and/or secondary education using a blended learning curriculum. The method is implemented in a school comprising students of mixed-age and/or mixed-grade level. The students are provided with a curriculum that combines machine-guided teaching with face-to-face teaching. One or more of the senior students assist one or more of the junior students with the machine-guided teaching. | 10-30-2014 |
20150154722 | Crime Deterrence Using Smartphone Signatures - A method and system of deterring crime by analyzing short-range signals broadcast by mobile wireless personal communication devices. Business places have sensors that are used to detect the short-range broadcast signals. The device signatures are identified by the short-range broadcast signals. When there is a crime event at the business place, a suspect device signature is identified. | 06-04-2015 |
20150305824 | Technique for Inserting Medical Instruments Using Head-Mounted Display - Techniques for performing image-guided medical procedures using a wearable, head-mounted image display apparatus, which displays images from medical imaging equipment. The clinician views the images provided by the head-mounted image display apparatus to help in inserting medical instruments into a patient's body. Examples of such medical procedures include ultrasound-guided needle/catheter procedures and laryngoscope-guided tracheal intubation. Being able to view the images while simultaneously having a direct view of the procedure site can improve procedure performance. Equipment for performing such procedures include camera laryngoscopes, transesophageal echocardiography apparatus, endoscopic imaging apparatus, x-ray fluoroscope apparatus, or medical ultrasound apparatus. | 10-29-2015 |
Patent application number | Description | Published |
20080276509 | Exit signs with and without emergency lighting - Emergency signs and combination emergency signs and emergency lights wherein the combination signs are compact for shipment and are energy efficient using first interior light emitting diodes, powered by an AC power source, for illumination of messages formed in at least one side wall of the emergency signs and having at least one emergency light emitting diode lamp for providing emergency lighting in the event of AC power failure and wherein the at least one emergency light emitting diode lamp, in some embodiments, is selectively deployable and adjustable relative to the signs, and in others, is fixedly mounted relative to the signs. | 11-13-2008 |
20100248401 | Kind of Method of Constituting Light Source using Multiple Light-emitting units - A method for forming a light source by plurality of light-emitting units, includes: step (A), determining the number of the light-emitting units based on following factors: the factors include a maximum supply voltage of a power supply circuit and a working voltage of each of the light-emitting units; step (B), determining a set power of each of the light-emitting units based on a set power of the light source and the number of the light-emitting units determined in the step (A); step (C), fabricating or selecting each of the light-emitting units based on the working voltage of each of the light emitting units and the set power of each of the light-emitting units determined in the step (B); step D), forming the light source by connecting each of the light-emitting units obtained in the step (C) in series according to the number of the light-emitting units determined in the step (A). For the light source formed as the above method, the high efficient power supply with the maximum output voltage, to the light source load, can be realized and the same power supply circuit can supply power to the light source with different set power with maximum supply efficiency. | 09-30-2010 |
20110001150 | LIGHT EMITTING DIODE AND METHOD FOR FABRICATING THEREOF - The present invention provides a light-emitting diode (LED) and a method for manufacturing said LED. The LED is characterized that, the silica gel as the interlayer is provided between the transparent organic material and the chip. The method for manufacturing is characterized that, a gel applying step for applying the silica gel and the solidifying step for solidifying the semi-finished product of LED applied with the silica gel are included prior to the material packaging step for packaging using the transparent organic material. The LED of this invention and the LED manufactured by the method of this invention have no light decay for the low-power, such as Ø5 mm or less LED, and little light decay for the high-power LED, and have the advantages of excellent weathering resistance and low production cost. | 01-06-2011 |
20110074372 | Architecture of a Power Supply Circuit with Power Factor Correction - An improved architecture of a power supply circuit with power factor correction, the power supply circuit includes power supply circuit output terminals and a voltage negative feedback circuit, the power supply circuit output terminals include a high potential terminals and a low potential terminals, the voltage negative feedback circuit includes a first feedback circuit and a second feedback circuit connected in series in order from the high potential terminal to the low potential terminal, a connection point of the first feedback circuit and the second feedback circuit acts as a feedback signal output terminal through which the voltage negative feedback circuit outputs a feedback signal, in the improved architecture, the first feedback circuit is replaced by a light source branch including a constant-current light source, and the second feedback circuit is replaced by a resistor branch for determining a working current of the light source branch. This improved architecture can perform a constant-current supply with high power factor and high efficiency for the light source. | 03-31-2011 |
20120176787 | METHOD OF MAKING HIGH COLOR RENDERING (CRI) LED LIGHTS AND HIGH COLOR RENDERING INDEX LED LIGHTS - A high color rendering index light and method of forming the same wherein the light is formed from at least two light emitting diodes each having color temperatures which are close enough to one another to be visually the same and which are connected in series and wherein each of which has a different color rendering index and wherein at least one of the at least two light emitting diodes has a high Color Rendering Index Value of at least Ra 80. | 07-12-2012 |
Patent application number | Description | Published |
20150306578 | METHOD OF PREPARING HIGH ACTIVITY HYDROTREATING CATALYSTS - This disclosure relates to supported multi-metallic catalysts for use in the hydrotreating of hydrocarbon feeds, as well as a method for preparing such catalysts. The catalysts are prepared from a catalyst precursor comprised of at least one Group VIB metal, at least one Group VIII metal and an organic acid. The catalyst precursor is thermally treated to partially decompose the organic acid, then sulfided. The catalysts have a high carbon-as-carboxyl to total carbon ratio (C | 10-29-2015 |
20150306591 | HIGH ACTIVITY HYDROTREATING CATALYSTS - This disclosure relates to supported multi-metallic catalysts for use in the hydrotreating of hydrocarbon feeds, as well as a method for preparing such catalysts. The catalysts are prepared from a catalyst precursor comprised of at least one Group VIB metal, at least one Group VIII metal and an organic acid. The catalyst precursor is thermally treated to partially decompose the organic acid, then sulfided. The catalysts have a high carbon-as-carboxyl to total carbon ratio (C | 10-29-2015 |
20150307789 | HIGH ACTIVITY HYDROTREATING CATALYSTS AND PROCESSES USING THE SAME - This disclosure relates to supported multi-metallic catalysts for use in the hydrotreating of hydrocarbon feeds. The catalysts are prepared from a catalyst precursor comprised of at least one Group VIB metal, at least one Group VIII metal and an organic acid. The catalyst precursor is thermally treated to partially decompose the organic acid, then sulfided. The catalysts have a high carbon-as-carboxyl to total carbon ratio (C | 10-29-2015 |
Patent application number | Description | Published |
20130131153 | CULLIN 5 AS A REGULATOR OF HSP90 CLIENTS: A NEW TARGET FOR DRUG DEVELOPMENT - Cullin5 (Cul5) E3 ubiquitin ligase is shown to be linked with the heat shock protein 90 (Hsp90) chaperone complex. Hsp90 participates in the folding of its client proteins into their functional conformation. Many Hsp90 clients have been reported to be aberrantly expressed in a number of cancers. Cul5 is shown to interact with members of the Hsp90 chaperone complex as well as the Hsp90 client, ErbB2, Cul5 is recruited to the site of ErbB2 at the plasma membrane and subsequent induction of polyubiquitination and proteasomal degradation. Cul5 is also involved in the regulation of another Hsp90 client, Hif-1α Cul5 degradation of ErbB2 occurs independently of ElonginB-ElonginC function. The involvement of Cul5 in Hsp90 client regulation has implications in the effectiveness of Hsp90 targeted chemotherapy, which is currently undergoing clinical trials. The link between Cul5 and Hsp90 client regulation may represent an avenue for cancer drug development. | 05-23-2013 |
20140057948 | VIF AS A TARGET FOR HIV INHIBITION - The present invention relates, e.g., to a method for inhibiting infectivity of a lentivirus (e.g., a lentivirus which expresses a Viral infectivity factor (Vif) protein), such as, e.g., SIV, SHIV and/or HIV, comprising contacting a cell which is producing the virus with an antiviral-effective amount of a membrane-permeable Zinc (Zn) chelator, wherein the antiviral-effective amount of the Zn chelator does not substantially inhibit proteins in the cell which contain Zn-binding motifs other than lentivirus Vif. Kits and pharmaceutical compositions are also disclosed, as is a method for identifying inhibitors of lentiviruses that target a specific zinc-binding motif of the lentivirus Vif protein. | 02-27-2014 |
Patent application number | Description | Published |
20100020932 | TREATMENT-SPEED REGULATED TUMOR-TRACKING - A method for delivering therapeutic radiation during a radiation treatment procedure to a tumor moving within a patient due to physiological activity of the patient includes:
| 01-28-2010 |
20100034348 | METHOD AND SYSTEM FOR TRANSLATIONAL DIGITAL TOMOSYNTHESIS MAMMOGRAPHY - A method of imaging a breast comprising (i) having a patient lie prone on a computer-controlled couch, which comprises a channel or left and right openings, and position the left or right breast of the patient in the channel or the left or right opening, respectively, and (ii) repeatedly imaging the breast using a scanning x-ray source while moving the couch down and up, such that the breast moves down and up in the field between the source of radiation and the detector, which method can further comprise constructing a three-dimensional image of the breast in its natural shape and analyzing the three-dimensional image of the breast; and a system for use in such a method. | 02-11-2010 |
20100094119 | METHOD AND EQUIPMENT FOR IMAGE-GUIDED STEREOTACTIC RADIOSURGERY OF BREAST CANCER - A method of treating a cancerous region in a breast of a patient comprising (i) imaging the breast in a three-dimensional coordinate system, (ii) stereotactically determining the location of the cancerous region in the breast, (iii) optionally determining the volume of the entire cancerous region to be treated, and (iv) while maintaining the breast in a three-dimensional coordinate system that is identical to or corresponds with the three-dimensional coordinate system used in (i), noninvasively exposing the cancerous region of the breast of the patient to a cancer-treatment effective dose of radiation; and equipment for use in such a method. | 04-15-2010 |
20110222660 | RADIATION SCULPTING BY COORDINATING ROTATION OF FIXED BEAMS AND MOTION OF PATIENT SUPPORT SYSTEM - A method of irradiating a target tissue in a patient comprising positioning the patient on a patient support system so that the target tissue in the patient is within irradiating distance of at least one source of a beam of radiation and moving the patient support system relative to the at least one source of a beam of radiation and, coordinately with movement of the patient support system, rotating the at least one source of radiation relative to the target tissue, which comprises and/or is adjacent to a non-target tissue, so that the center of rotation of the beam of radiation is placed at one or more desired locations within the target tissue, while simultaneously and/or sequentially irradiating the target tissue; a collimator; a method of making such a collimator; a system for irradiating a target tissue in a patient; and a method of planning irradiation of a target tissue in a patient. | 09-15-2011 |
20120198624 | METHOD AND DEVICE FOR PATIENT LOADING AND POSITIONING - A method and device for accurately positioning patients for imaging and radiotherapy is disclosed. The device includes a support platform (such as a bed, a table, a couch, a chair, etc.) connected to a fixed base by at least two and preferably four offset supporting arms. The support arms are journaled into the support platform at passive-rotatable pivot joints and are journaled into the base at active-rotatable pivot points. The base contains actuators (manual or powered by motors, pneumatics or hydraulics) for articulating the support arms. The relative lengths of the support arms may be varied to create a pre-defined trajectory of the support platform, between a starting spatial position and orientation to an ending spatial position and orientation, and through a continuous range there between. This makes it possible to position a patient within a range from a low, standing up position to a high, forwarding, prone or supine position, or vice versa. | 08-09-2012 |
Patent application number | Description | Published |
20140235962 | APPARATUS, SYSTEM AND METHOD FOR MULTI-MODAL VOLUMETRIC ULTRASOUND IMAGING AND BIOPSY OF A SINGLE BREAST - An apparatus for volumetric ultrasound imaging of a breast using different modes, including transmission, reflection and the speed of sound, which apparatus comprises a negatively pressurized breast imaging cup with integrated ultrasound transducers and an ultrasound coupling mechanism; an ultrasound system comprising the apparatus; and a method of imaging a breast in three dimensions without moving the ultrasound transducers. | 08-21-2014 |
20140275704 | METHODS AND SYSTEM FOR BREATHING-SYNCHRONIZED, TARGET-TRACKING RADIATION THERAPY - Preparing a plan to synchronize radiation delivery to a target in a patient with patient breathing phase and amplitude as the independent variable comprising (a) obtaining simultaneous data on patient breathing and target shape and location, (b) correlating the data and optimizing the correlation, (c) establishing optimal parameters of radiation delivery for each breathing phase/amplitude or for each target shape/location; and (d) synchronizing radiation delivery to a target in a patient with patient breathing comprising (a) positioning the patient, (b) monitoring actual breathing or the shape/location of the target, and (c) while monitoring, delivering radiation to the target according to a plan; and a system for controlling radiation delivery by a device to a target in a patient comprising (i) a processor, which receives and processes data on breathing or the shape/location of the target, and (ii) a controller, which controls radiation delivery to the target according to a plan, which synchronizes radiation delivery to the target with breathing data or the shape/location of the target. | 09-18-2014 |
20150190658 | METHOD AND SYSTEM FOR STEREOTACTIC INTENSITY-MODULATED ARC THERAPY - A method of irradiating a target in a patient comprising directing a beam of radiation from an external source of radiation | 07-09-2015 |
Patent application number | Description | Published |
20100015113 | GP100-SPECIFIC T CELL RECEPTORS AND RELATED MATERIALS AND METHODS OF USE - The invention provides human cells, particularly human T cells, comprising a murine T Cell Receptor (TCR) having antigen specificity for the cancer antigen gp100. Isolated or purified TCRs having antigenic specificity for amino acids 154-162 of gp100 (SEQ ID NO: 1), as well as related polypeptides, proteins, nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, or antigen binding fragments thereof, conjugates, and pharmaceutical compositions, are further provided. The invention further provides a method of detecting the presence of cancer in a host and a method of treating or preventing cancer in a host comprising the use of the inventive materials described herein. | 01-21-2010 |
20120230962 | GP100-SPECIFIC T CELL RECEPTORS AND RELATED MATERIALS AND METHODS OF USE - The invention provides human cells, particularly human T cells, comprising a murine T Cell Receptor (TCR) having antigen specificity for the cancer antigen gp100. Isolated or purified TCRs having antigenic specificity for amino acids 154-162 of gp100 (SEQ ID NO: 1), as well as related polypeptides, proteins, nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, or antigen binding fragments thereof, conjugates, and pharmaceutical compositions, are further provided. The invention further provides a method of detecting the presence of cancer in a host and a method of treating or preventing cancer in a host comprising the use of the inventive materials described herein. | 09-13-2012 |