Patent application number | Description | Published |
20090099221 | PYRIDYL-AND PYRIMIDINYL-SUBSTITUTED PYRROLE-, THIOPHENE-AND FURANE-DERIVATIVES AS KINASE INHIBITORS - The present invention provides compounds of the formula (I), or the pharmaceutically acceptable salts thereof, wherein G, W, R | 04-16-2009 |
20100075998 | TRICYCLIC INDOLES AND (4,5-DIHYDRO) INDOLES - The present invention provides tricyclic indoles and (4,5-dihydro) indoles of the formula (I) or a pharmaceutically acceptable salt thereof: wherein the ring A represents a fused pyrazole, pyridine or pyrimidine, | 03-25-2010 |
20120157454 | ISOQUINOLIN-1 (2H) -ONE DERIVATIVES AS PARP-1 INHIBITORS - There are provided substituted isoquinolin-1(2H)-one derivatives which selectively inhibit the activity of poly (ADP-ribose) polymerase PARP-1 with respect to poly (ADP-ribose) polymerase PARP-2. The compounds of the present invention are therefore useful in treating diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds. A screening method for the identification of compounds capable of binding several PARP proteins, as well the probes used in such method, are further objects of the invention. | 06-21-2012 |
20120245142 | 3-OXO-2,3-DIHYDRO-1H-ISOINDOLE-4-CARBOXAMIDES AS PARP INHIBITORS - There are provided substituted 3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide derivatives (I) which selectively inhibit the activity of poly (ADP-ribose) polymerase PARP-1 with respect to poly (ADP-ribose) polymerase PARP-2. The compounds of this invention are therefore useful in treating diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating, diseases utilizing pharmaceutical compositions comprising these compounds. | 09-27-2012 |
20120295906 | PYRIDYL-AND PYRIMIDINYL-SUBSTITUTED PYRROLE-, THIOPHENE-AND FURANE-DERIVATIVES AS KINASE INHIBITORS - The present invention provides compounds of the formula (I), or the pharmaceutically acceptable salts thereof, wherein G, W, R | 11-22-2012 |
20140045846 | ISOQUINOLIN-1(2H)-ONE DERIVATIVES AS PARP-1 INHIBITORS - There are provided substituted isoquinolin-1(2H)-one derivatives which selectively inhibit the activity of poly (ADP-ribose) polymerase PARP-1 with respect to poly (ADP-ribose) polymerase PARP-2. The compounds of the present invention are therefore useful in treating diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds. A screening method for the identification of compounds capable of binding several PARP proteins, as well the probes used in such method, are further objects of the invention. | 02-13-2014 |
20150051237 | PYRIDYL-AND PYRIMIDINYL-SUBSTITUTED PYRROLE-, THIOPHENE- AND FURANE-DERIVATIVES AS KINASE INHIBITORS - The present invention provides compounds of the formula (I), or the pharmaceutically acceptable salts thereof, wherein G, W, R | 02-19-2015 |
20150218138 | PYRIDYL-AND PYRIMIDINYL-SUBSTITUTED PYRROLE-, THIOPHENE- AND FURANE-DERIVATIVES AS KINASE INHIBITORS - The present invention provides compounds of the formula (I), or the pharmaceutically acceptable salts thereof, wherein G, W, R | 08-06-2015 |
Patent application number | Description | Published |
20120299759 | ANALOG TO DIGITAL CONVERSION APPARATUS - An analog to digital conversion includes a multiplexor circuit for receiving analog input signals and, responsive to a select input, an analog to digital converter circuit to convert a selected analog signal into a digital signal, a conversion starting device to send a conversion start signal on the basis of a trigger event, the conversion starting device being responsive to a select input, a sequencer to control the analog to digital converter circuitry to execute one sequence conversion on the basis of one conversion sequence instruction, and a FIFO register block to receive conversion sequence instructions and being able to queue each new received conversion sequence instruction if an actual conversion sequence is in progress and to control the sequencer to execute a new sequence conversion instruction after the conversion sequence is executed. | 11-29-2012 |
20120299760 | SEQUENCE ARBITER FOR ANALOG-TO-DIGITAL CONVERSIONS - An analog-to-digital converter device may include an input multiplexer circuit having analog input terminals configured to receive a respective plurality of analog input signals. The input multiplexer circuit may be responsive to a first select input. The device may also include a trigger multiplexer circuit having input terminals configured to receive respective triggering signals. The trigger multiplexer circuit may be responsive to a second select input. Analog-to-digital converter circuitry may be configured to convert the selected analog signal into a digital signal. A sequence arbiter may be coupled to the first and second select inputs and may have input terminals configured to receive a respective plurality of conversion sequence configuration signals. The sequence arbiter may be configured to manage each conversion sequence of the analog-to-digital converter circuitry based upon the relative conversion sequence configuration signal received, and control the conversion sequences. | 11-29-2012 |
20140043180 | ANALOG TO DIGITAL CONVERSION APPARATUS WITH A REDUCED NUMBER OF ADCs - An analog to digital conversion includes a multiplexor circuit for receiving analog input signals and, responsive to a select input, an analog to digital converter circuit to convert a selected analog signal into a digital signal, a conversion starting device to send a conversion start signal on the basis of a trigger event, the conversion starting device being responsive to a select input, a sequencer to control the analog to digital converter circuitry to execute one sequence conversion on the basis of one conversion sequence instruction, and a FIFO register block to receive conversion sequence instructions and being able to queue each new received conversion sequence instruction if an actual conversion sequence is in progress and to control the sequencer to execute a new sequence conversion instruction after the conversion sequence is executed. | 02-13-2014 |
Patent application number | Description | Published |
20150044069 | MECHANICAL COMBUSTION-ENGINE-DRIVEN FLUID PUMP - A mechanical fluid pump driven by a combustion engine includes an input shaft which is directly driven by the combustion engine, a pumping unit comprising a pump rotor, and a clutch arranged between the input shaft and the pump rotor. The clutch is provided as a magneto-rheological clutch comprising two clutch bodies, a fluid gap arranged between the two clutch bodies, the fluid gap being filled with a magneto-rheological fluid, and a permanent magnet element which is shiftable between an engaged position where a magnetic field penetration flux of the permanent magnet element penetrates the fluid gap with a high magnetic flux, and a disengaged position where the magnetic field penetration flux of the permanent magnet element is less than in the engaged position. An actuator is configured to move the permanent magnet element between the engaged position and the disengaged position. | 02-12-2015 |
20150260240 | MECHANICAL COMBUSTION-ENGINE-DRIVEN FLUID PUMP - A mechanical combustion-engine-driven fluid pump includes an input shaft driven by a combustion engine, a pumping unit comprising a pump rotor, and a clutch arranged between the input shaft and the pump rotor. The clutch comprises an input clutch body, an output clutch body, an electroconductive element, a permanent magnet element, and an actuator. The clutch transfers a rotation of the input clutch body to the output clutch body in an engaged clutch state. The closed clutch liquid gap is formed between the input clutch body and the output clutch body, and is filled with a magneto-rheological clutch liquid. The electroconductive element co-rotates with the output clutch body. The permanent magnet element co-rotates with the input clutch body and is shiftable between an engaged position and a disengaged position. The actuator moves the permanent magnet element between the engaged position and the disengaged position. | 09-17-2015 |
20150308432 | MECHANICAL COMBUSTION-ENGINE-DRIVEN FLUID PUMP - A fluid pump includes an input shaft, a pumping unit comprising a pump rotor, and a clutch arranged between the input shaft and the pump rotor. The clutch comprises at least two input clutch disks, at least two output clutch disks, a permanent magnet element, and an actuator. The at least two input clutch disks and the at least two output clutch discs together define at least two clutch liquid gaps which are filled with a magneto-rheological clutch liquid. The permanent magnet element shifts between an engaged position wherein a magnetic field of the permanent magnet element penetrates the at least two clutch liquid gaps with a high magnetic flux, and a disengaged position wherein the magnetic field of the permanent magnet element is less than in the engaged position. The actuator moves the permanent magnet element between the engaged position and the disengaged position. | 10-29-2015 |
Patent application number | Description | Published |
20090063025 | METHOD AND DEVICES EQUIPPED WITH A HIGH-PASS FILTER FOR APPRAISAL OF THE KNOCKING IN EVERY CYLINDER OF AN INTERNAL COMBUSTION ENGINE - The invention relates to the field of methods and devices for evaluating the knocking inside every cylinder of an internal combustion engine by making advantageous use of the ionisation current generated during the combustion of the fuel in each cylinder of said engine. The invention develops over various phases, each of which is repeated continually for each cycle of said combustion engine and is characterised by the fact that ionisation current values are selected during determined lengths of time, and said values are entered in a high-pass filter, the values determined by said filter then being squared and the value Vd calculated, said value being the relation between the value of the sum of the squares of said values obtained by said filter and a known normalisation coefficient, thus generating the spark at the spark plug in each cylinder on the basis of said value Vd. | 03-05-2009 |
20090125210 | METHOD AND DEVICE FOR THE DETERMINATION AND INPUT OF FUEL INTO AN INTERNAL COMBUSTION ENGINE ON THE BASIS OF AN AIR-FUEL RATIO TARGET AND IONIC CURRENT SENSOR - The invention relates to the field of method and devices for determining and putting in fuel into an internal combustion engine on the basis of an air-fuel ratio in proximity to the stoichiometric value. The present invention is based on the use of the ion current released by a device, positioned on each cylinder of said engine. This ion current is acquired by a Control Unit equipped by means, preferably electronic ones, which implement the invention, repeated continually for each engine cycle and for each cylinder, characterized in that said method develops over various phases. | 05-14-2009 |
20090301177 | METHOD AND DEVICES TO IDENTIFY THE PISTON IN THE COMPRESSION PHASE IN AN INTERNAL COMBUSTION ENGINE EQUIPPED WITH A GASOLINE INDIRECT ELECTRONIC INJECTION SYSTEM - The invention relates to the field of method and devices therefore for identifying which cylinder is in the compression phase in a gasoline indirect electronic injection internal combustion engine. | 12-10-2009 |
20090326786 | METHOD AND DEVICES FOR THE CONTROL OF THE AIR-FUEL RATIO OF AN INTERNAL COMBUSTION ENGINE - The present invention fall into the field of methods and devices therefor for controlling the normalised air-fuel ratio of an internal combustion engine, otherwise known, in technical terms, as Lambda. The present invention is based on the use of the ionisation current released by a device positioned on each cylinder of said engine. This ionisation current is measured by a Control Unit equipped with a low-pass filter and electronic means which implement the invention. | 12-31-2009 |
20100064772 | METHOD AND DEVICES FOR THE IDENTIFICATION OF VARIOUS PHASES OF AN IONIZATION CURRENT SIGNAL DURING THE COMBUSTION IN AN INTERNAL COMBUSTION ENGINE - The present invention falls into the field of methods and devices for identifying the various phases of the ionization current during combustion in a cylinder of an internal combustion engine. | 03-18-2010 |
20100070157 | METHOD AND DEVICES TO REDUCE THE DIFFERENCE BETWEEN NORMALIZED AIR-FUEL RATIO OF THE VARIOUS CYLINDERS IN AN INTERNAL COMBUSTION ENGINE AND A PREDETERMINED VALUE - The invention relates to the field of methods and devices for reducing the difference between normalized air-fuel ratio of the various cylinders compared with a predetermined value between 0.7 and 1.1, of the normalized air-fuel ratio in an internal combustion engine. The method and devices utilize the signal of the ionization current produced by a suitable device, modifying the quantity of fuel on the basis of the signal determined by means of the method in question in the invention. | 03-18-2010 |