Patent application number | Description | Published |
20110250289 | BONE SUBSTITUTE AND METHOD FOR THE PREPARATION THEREOF - The invention relates to a material that can be used as a bone substitute and to a method for the preparation thereof. The material comprises an organic phase (I) comprising striated collagen fibrils constituted of collagen I triple helices, said fibrils being organized over a large distance according to a 3D geometry associating aligned domains and cholesteric domains, and also isotropic domains where they are not organized; and a mineral phase (II) comprising apatite crystals having a hexagonal crystalline structure, space group 6/m, comprising at least calcium ions and phosphate ions; the axis c of said apatite crystals of the mineral phase is coaligned with the longitudinal axis of the striated collagen fibrils of the organic phase and the collagen content in the material is at least 75 mg/cm | 10-13-2011 |
20120076870 | BONE SUBSTITUTE AND METHOD FOR THE PREPARATION THEREOF - The invention relates to a material that can be used as a bone substitute and to a method for the preparation thereof. The material comprises an organic phase (I) comprising striated collagen fibrils constituted of collagen I triple helices, said fibrils being organized over a large distance according to a 3D geometry associating aligned domains and cholesteric domains, and also isotropic domains where they are not organized; and a mineral phase (II) comprising apatite crystals having a hexagonal crystalline structure, space group 6/m, comprising at least calcium ions and phosphate ions; the axis c of said apatite crystals of the mineral phase is coaligned with the longitudinal axis of the striated collagen fibrils of the organic phase and the collagen content in the material is at least 75 mg/cm | 03-29-2012 |
20130142840 | DENSE FIBRILLAR COLLAGEN MATRICES FOR TISSUE REPAIR AND THE PREPARATION METHOD THEREOF - Method for preparing a homogeneous collagen-based material by concentration of a collagen solution, includes bringing a collagen solution into contact by way of continuous injection and use of the material for tissue repair. | 06-06-2013 |
Patent application number | Description | Published |
20130165916 | METHODS AND APPARATUSES FOR REMODELING TISSUE OF OR ADJACENT TO A BODY PASSAGE - Medical devices and methods for making and using the same are disclosed. An example method may include a method for treating tissue near a body passageway using an apparatus including a catheter having a plurality of electrodes, a radio-frequency energy generator, and a controller coupling the energy generator to the plurality of electrodes and configured to selectively energize the electrodes. The method may include using the apparatus to subject the tissue near the body passageway to a plurality of energy treatment cycles. The treatment cycle may include determining desired voltages for at least a subset of the electrodes for maintaining a predetermined target temperature profile proximate the subset of electrodes, setting an output voltage of the energy generator to correspond to the desired voltage determined for one of the electrodes, and energizing at least some of the electrodes at the output voltage to deliver energy to the body passageway. | 06-27-2013 |
20130165917 | METHODS AND APPARATUSES FOR REMODELING TISSUE OF OR ADJACENT TO A BODY PASSAGE - Medical devices and methods for making and using the same are disclosed. An example method may include renal-denervation treatment method. The method may include delivering an RF energy treatment to a tissue proximate a renal artery using a catheter assembly of a renal denervation catheter system. The denervation system may include an RF energy generator coupled with the catheter assembly by a controller. The method may also include applying neural activity stimulation to the tissue proximate the renal artery using the catheter assembly, assessing stimulated neural activity response of the tissue using the catheter assembly, and determining a parameter of the RF energy treatment based on the assessed neural activity. | 06-27-2013 |
20130165923 | METHODS AND APPARATUSES FOR REMODELING TISSUE OF OR ADJACENT TO A BODY PASSAGE - Medical devices and methods for making and using the same are disclosed. An example device may include a catheter extending along a longitudinal axis. A balloon may be coupled to an end of the catheter. The balloon having a plurality of cylindrical treatment zones extending along the longitudinal axis in an expanded state. A plurality of electrode assemblies may be coupled to the balloon. Each electrode assembly may include a distal electrode pad and a proximal electrode pad. | 06-27-2013 |
20130165924 | METHODS AND APPARATUSES FOR REMODELING TISSUE OF OR ADJACENT TO A BODY PASSAGE - Medical devices and methods for making and using the same are disclosed. An example device may include an expandable balloon including an outer surface. At least one flexible circuit may be mounted on the outer surface of the expandable balloon. The at least one flexible circuit may include a first insulating layer, at least one heat sensing device positioned at least partially within the first insulating layer, a conductive layer above the first insulating layer, at least a portion of which is electrically coupled to the heat sensing device, a second insulating layer above the conductive layer, and at least one electrode associated with the conductive layer. | 06-27-2013 |
20130165925 | METHODS AND APPARATUSES FOR REMODELING TISSUE OF OR ADJACENT TO A BODY PASSAGE - Medical devices and methods for making and using the same are disclosed. An example medical device may include a catheter. The catheter may include an elongate flexible catheter body. An expandable structure may be associated with the catheter body and may include a radially expandable balloon and a plurality of flexible circuits extending along an outer surface of the balloon. Each flexible circuit may include at least one electrode and at least one temperature sensor. The expandable structure may have an outer diameter of less than 4 mm when in an expanded configuration. | 06-27-2013 |
20130165926 | METHODS AND APPARATUSES FOR REMODELING TISSUE OF OR ADJACENT TO A BODY PASSAGE - Medical devices and methods for making and using the same are disclosed. An example medical device may include a catheter shaft. An expandable member may be coupled to the catheter shaft. A plurality of flexible electrode assemblies may be coupled to the expandable member. A control unit may be coupled to the electrode assemblies. The control unit may be configured to energize the electrode assemblies for approximately 10 seconds to less than approximately 1 minute. | 06-27-2013 |
20130165990 | METHODS AND APPARATUSES FOR REMODELING TISSUE OF OR ADJACENT TO A BODY PASSAGE - Medical devices and methods for making and using the same are disclosed. An example method may include a method for treating a patient having congestive heart failure. The method may include positioning an expandable balloon in a renal artery of the patient. The expandable balloon may include a plurality of electrode assemblies. At least some of the electrode assemblies each may include at least two bipolar electrode pairs. The two bipolar electrode pairs may be longitudinally and circumferentially offset from one another. The method may also include expanding the balloon in the renal artery such that at least some of the bipolar electrode pairs are electrically coupled to a wall of the renal artery and energizing at least some of the bipolar electrode pairs so as to therapeutically alter at least one nerve proximate the renal artery to treat the patient's congestive heart failure. | 06-27-2013 |
20150216591 | ALTERNATIVE PLACEMENT OF THERMAL SENSORS ON BIPOLAR ELECTRODE - A medical device for tissue ablation may include a catheter shaft, an expandable member disposed on or coupled to the catheter shaft, and a plurality of elongate electrode assemblies each constructed as a flexible circuit. The expandable member may be configured to shift between an unexpanded configuration and an expanded configuration. The plurality of electrode assemblies may be disposed on an outer surface of the expandable member. Each of the plurality of electrode assemblies may include a temperature sensor aligned with two or more electrodes. | 08-06-2015 |
Patent application number | Description | Published |
20110173577 | Techniques for Pattern Process Tuning and Design Optimization for Maximizing Process-Sensitive Circuit Yields - Techniques for improving circuit design and production are provided. In one aspect, a method for virtual fabrication of a process-sensitive circuit is provided. The method comprises the following steps. Based on a physical layout diagram of the circuit, a virtual representation of the fabricated circuit is obtained that accounts for one or more variations that can occur during a circuit production process. A quality-based metric is used to project a production yield for the virtual representation of the fabricated circuit. The physical layout diagram and/or the production process are modified. The obtaining, using and modifying steps are repeated until a desired projected production yield is attained. | 07-14-2011 |
20130096976 | COST-EFFECTIVE AND RELIABLE UTILITIES DISTRIBUTION NETWORK - A method, system, and computer program product for designing a cost-effective and reliable distribution network for a utility are provided in the illustrative embodiments. A graph connecting a set of consumers of the utility with a set of suppliers of the utility is reduced to form a plurality of clusters. A first network between a supplier and a subset of consumers in a first cluster in the plurality of clusters is improved, the improving adding a first connection in the first network to provide continuity of supply of the utility to the subset of consumers after a predetermined number of failures in the first network. A design is generated for a second network connecting the set of suppliers to the set of consumers, the second network including the first network after the improving, wherein the second network has a cost that is within a lower threshold and an upper threshold. | 04-18-2013 |
20130158953 | VISUALIZING SENSITIVITY INFORMATION IN INTEGRATED CIRCUIT DESIGN - A method, system, and computer program product for visualizing sensitivity information in integrated circuit (IC) design are provided in the illustrative embodiments. A plurality of sensitivity information corresponding to a first component in the IC design is received, wherein the plurality of sensitivity information includes a first sensitivity information indicating a first variation in a first electrical characteristic of a group of components as a result of a variation in an electrical characteristic of the first component. A plurality of aspects of the first sensitivity information are rendered in visual form to form a first visualization. The first visualization is presented on a schematic view of the IC design in an IC design tool such that the first sensitivity information is visually associated with the first component in the IC design. | 06-20-2013 |
20130159946 | GUIDING DESIGN ACTIONS FOR COMPLEX FAILURE MODES - A system, and computer program product for guiding design actions for complex failure modes in an integrated circuit (IC) design are provided in the illustrative embodiments. A probability of failure estimate of a circuit according to the IC design is received, the probability being determined using a simulation. A sensitivity of the probability of failure to a variable associated with a component in the circuit is calculated, wherein the sensitivity is determined by an estimation without the simulation. The sensitivity is depicted relative to the component in the IC design such that the sensitivity is associated with the component and a visual relationship between the component and the sensitivity is usable for adjusting a characteristic of the component to reduce the probability of failure of the circuit. | 06-20-2013 |
20130159947 | GUIDING DESIGN ACTIONS FOR COMPLEX FAILURE MODES - A method for guiding design actions for complex failure modes in an integrated circuit (IC) design is provided in the illustrative embodiments. A probability of failure estimate of a circuit according to the IC design is received, the probability being determined using a simulation. A sensitivity of the probability of failure to a variable associated with a component in the circuit is calculated, wherein the sensitivity is determined by an estimation without the simulation. The sensitivity is depicted relative to the component in the IC design such that the sensitivity is associated with the component and a visual relationship between the component and the sensitivity is usable for adjusting a characteristic of the component to reduce the probability of failure of the circuit. | 06-20-2013 |
20130159948 | LAYOUT-SPECIFIC CLASSIFICATION AND PRIORITIZATION OF RECOMMENDED RULES VIOLATIONS - A method, system, and computer program product for classifying and prioritizing a set of recommended rule (RR) violations in an integrated circuit (IC) design are provided in the illustrative embodiments. The set of RR violations is received. A layout corresponding to the IC design is received. A set of features is selected in the layout. A classification model corresponding to the set of features is selected. Using the set of features and the classification model, the first RR violation is classified into a classification from a set of classifications. The classification is prioritized in an order of priority such that the first RR violation in the classification is recommended for remedying in the order of priority. | 06-20-2013 |
20130159955 | DYNAMIC PIN ACCESS MAXIMIZATION FOR MULTI-PATTERNING LITHOGRAPHY - A method, system, and computer program product for improving pin access in a design of an integrated circuit (IC) for multi-patterning lithography (MPL) are provided in the illustrative embodiments. A cell is placed in the IC design, the cell including a pin shape configured to connect a pin of the cell to a semi-conductor component in the IC design, the cell including a coloring conflict due to the pin shape and an other shape in the cell each being colored using a first color for fabricating onto a wafer using MPL. A net is routed to the pin shape without resolving the coloring conflict, wherein the routing routes the net using a first segment of the pin shape. The pin shape is modified after routing to resolve the coloring conflict to result in a modified cell. | 06-20-2013 |
Patent application number | Description | Published |
20090155886 | NUCLEIC ACIDS AND POLYPEPTIDES SPECIFIC FOR PATHOGENIC STRAINS OF THE NEISSERIA GENUS - The invention concerns nucleic acids coding for polypeptides specific of the | 06-18-2009 |
20090298713 | POLYNUCLEOTIDES WHICH ARE OF NATURE B2/D+ A- AND WHICH ARE ISOLATED FROM E. COLI, AND BIOLOGICAL USES OF THESE POLYNUCLEOTIDES AND OF THEIR POLYPEPTIDES - The present invention relates to products which are of nature B2+ A−, isolated from | 12-03-2009 |
20090305275 | DNAs AND PROTEINS OR PEPTIDES SPECIFIC TO BACTERIA OF THE SPECIES NEISSERIA MENINGITIDIS, PROCESS FOR OBTAINING THEM AND THEIR BIOLOGICAL USES - The DNA of the invention are characterised in that they concern the whole or pan of genes, with their reading frame, to be found in | 12-10-2009 |
20100116980 | Means for identifying a strain isolated from a clinical sample at the species and/or subspecies level - The invention relates to a method for identifying a strain isolated from a clinical sample, at the species and/or subspecies level, using MALDI-TOF-MS analysis comprising a step of classifying the germ in a group before performing the MALDI-TOF-MS analysis | 05-13-2010 |
20100184639 | NUCLEIC ACIDS AND POLYPEPTIDES SPECIFIC OF THE NEISSERIA GENUS PATHOGENIC STRAINS - The invention concerns nucleic acids coding for polypeptides specific of the | 07-22-2010 |
20110313026 | DNA AND PROTEINS OR PEPTIDES SPECIFIC OF BACTERIA OF THE NEISSERIA MENINGITIDIS SPECIES, METHODS FOR OBTAINING THEM AND BIOLOGICAL APPLICATIONS THEREOF - The DNA of the invention are characterised in that they concern the whole or part of genes, with their reading frame, to be found in | 12-22-2011 |
20110318776 | Method for identifying germs in a liquid medium - This invention relates to a method for identifying germs in a liquid medium, comprising adding a membrane detergent to the liquid medium containing components of a host infected with germs, i.e. cellular components and proteins from the extracellular environment, so as to release the germs from these components without degrading them, and in that the germs that have grown in the liquid medium are analysed by MALDI-TOF MS. | 12-29-2011 |
20130287808 | VACCINES FOR PREVENTING MENINGOCOCCAL INFECTIONS - The present invention stems from the finding that the interaction between the β2 adrenoceptor (β2AP) and type IV pilus-associated proteins initiates a process leading to the opening of the blood-brain barrier. The invention therefore pertains to a vaccine for preventing the spreading of meningococci into the meningeal space, wherein said vaccine allows the production of antibodies inhibiting the interaction between the type IV pilus-associated proteins and the β2AP. | 10-31-2013 |