Grover, MA
Paul Grover, Franklin, MA US
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20100125070 | Bupropion Metabolites and Methods of Their Synthesis and Use - Methods and compositions are disclosed which utilize metabolites of bupropion for treating disorders ameliorated by inhibition of neuronal monoamine reuptake. Such disorders include, but are not limited to, sexual dysfunction, affective disorders, cerebral function disorders, cigarette smoking, and incontinence. Methods of making optically pure bupropion metabolites are also disclosed. | 05-20-2010 |
Paul Grover, Plainville, MA US
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20090163456 | CARBONATE AND CARBAMATE MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH B2 ADRENERGIC AGONISTS - Compositions containing β | 06-25-2009 |
20130244988 | CARBONATE AND CARBAMATE MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH B2 ADRENERGIC AGONISTS - Compositions containing β | 09-19-2013 |
Paul Grover, Waltham, MA US
Patent application number | Description | Published |
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20120035134 | CHEMICAL COMPOUNDS - The present invention relates to compounds of Formula (I): | 02-09-2012 |
20130310344 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS - The present invention relates to compounds of Formula (I): and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit Bcl-2 and/or Bcl-X | 11-21-2013 |
Paul T. Grover, Plainville, MA US
Patent application number | Description | Published |
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20110166146 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS - Imidazo[1,2-a]pyridines are disclosed. Compounds of the invention are useful therapeutic agents and their inclusion in pharmaceutical formulations and use in methods of treatment are disclosed. | 07-07-2011 |
20130289013 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS - Imidazo[1,2-a]pyridines are disclosed. Compounds of the invention are useful therapeutic agents and their inclusion in pharmaceutical formulations and use in methods of treatment are disclosed. | 10-31-2013 |
Piyush Grover, Cambridge, MA US
Patent application number | Description | Published |
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20140032018 | System and Method for Estimating States of Spacecraft in Planet-Moon Environment - A method estimates a state of a spacecraft in a planet-moon environment by executing iteratively a particle filter. The particle filter comprising integrates individually states of each particle of the particle filter according to a probability-evolution equation using a model of the state of the spacecraft represented as a planar circular restricted three-body problem and determines a prior probability of each particle as a previous posterior probability of a corresponding particle during a previous iteration. A joint probability distribution of the state of the spacecraft is determines using the states of each particle and the prior probabilities of each particle and the states and the prior probabilities of each particle are updated according to the joint probability distribution of the state of the spacecraft and a measurement of the state of the spacecraft to produce posterior probabilities of each particle. | 01-30-2014 |
Terry L. Grover, South Hadley, MA US
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20080312489 | Fluorescent bulb mercury clean-up method - Described herein is a method and instrumentation for cleaning up mercury spilled from broken fluorescent light bulbs. The method provides for the safe clean-up of the mercury spilled from four or fewer four-foot bulbs (or their equivalent) without the use of a respirator or other respiratory protection, while avoiding the expense associated with contracting an environmental remediation firm to perform the clean-up. | 12-18-2008 |
William Grover, Medford, MA US
Patent application number | Description | Published |
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20100288043 | Method and apparatus for extended time and varying environment measurements of single particles in microfluidic channels - Methods and apparatus for improving measurements of particle or cell characteristics, such as mass, in Suspended Microchannel Resonators (SMR's). Apparatus include in particular designs for trapping particles in SMR's for extended measurement periods and for changing the fluid properties within the SMR during the extended periods. Methods include techniques to provide for cell growth over time and over time in response to changing fluid properties to aid in determining parameters such as drug resistance and drug susceptibility. | 11-18-2010 |
20140096604 | Method and Apparatus for Trapping Single Particles in Microfluidic Channels - Methods and apparatus for improving measurements of particle or cell characteristics, such as mass, in Suspended Microchannel Resonators (SMR's). Apparatus include in particular designs for trapping particles in SMR's for extended measurement periods. Methods include techniques to provide differential measurements by varying the fluid density for repeated measurements on the same particle or cell. | 04-10-2014 |
William H. Grover, Medford, MA US
Patent application number | Description | Published |
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20090060797 | FLUID CONTROL STRUCTURES IN MICROFLUIDIC DEVICES - Methods and apparatus for implementing microfluidic analysis devices are provided. A monolithic elastomer membrane associated with an integrated pneumatic manifold allows the placement and actuation of a variety of fluid control structures, such as structures for pumping, isolating, mixing, routing, merging, splitting, preparing, and storing volumes of fluid. The fluid control structures can be used to implement a variety of sample introduction, preparation, processing, and storage techniques. | 03-05-2009 |
20100154535 | Method and apparatus for trapping single particles in microfluidic channels - Methods and apparatus for improving measurements of particle or cell characteristics, such as mass, in Susppended Microchannel Resonators (SMR's). Apparatus include in particular designs for trapping particles in SMR's for extended measurement periods. Methods include techniques to provide differential measurements by varying the fluid density for repeated measurements on the same particle or cell. | 06-24-2010 |
20100224255 | FLUID CONTROL STRUCTURES IN MICROFLUIDIC DEVICES - Methods and apparatus for implementing microfluidic analysis devices are provided. A monolithic elastomer membrane associated with an integrated pneumatic manifold allows the placement and actuation of a variety of fluid control structures, such as structures for pumping, isolating, mixing, routing, merging, splitting, preparing, and storing volumes of fluid. The fluid control structures can be used to implement a variety of sample introduction, preparation, processing, and storage techniques. | 09-09-2010 |
20100252123 | MULTIPLEXED LATCHING VALVES FOR MICROFLUIDIC DEVICES AND PROCESSORS - Membrane valves and latching valve structures for microfluidic devices are provided. A demultiplexer can be used to address the latching valve structures. The membrane valves and latching valve structures may be used to form pneumatic logic circuits, including processors. | 10-07-2010 |
20100297747 | SYSTEM AND METHOD FOR MONITORING CELL GROWTH - Microsystem for monitoring cell growth. A microfluidic structure is designed to allow cells to circulate therethrough and the microfluidic structure includes modules to monitor mass, mass density and fluorescence of the cell. | 11-25-2010 |
20130263658 | Method and Apparatus for Trapping Single Particles in Microfluidic Channels - Methods and apparatus for improving measurements of particle or cell characteristics, such as mass, in Suspended Microchannel Resonators (SMR's). Apparatus include in particular designs for trapping particles in SMR's for extended measurement periods. Methods include techniques to provide differential measurements by varying the fluid density for repeated measurements on the same particle or cell. | 10-10-2013 |