Kristin M.
Kristin M. Bompiani, Durham, NC US
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20130210903 | APTAMERS TO GLYCOPROTEIN VI - The present invention relates, in general, to glycoprotein VI (GPVI) and, in particular, to aptamers to GPVI and to compositions comprising same. The invention also relates to methods of inhibiting platelet aggregation using an aptamer that binds to and inhibits the activity of GPVI. The invention further relates to antidotes to GPVI aptamers and to methods of using such antidotes to reverse aptamer-induced platelet inhibition. The invention also relates to aptamers that bind to and enhance the activity of GPVI. | 08-15-2013 |
Kristin M. Defife, San Diego, CA US
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20080288057 | Bioactive Stents For Type II Diabetics and Methods for Use Thereof - The present invention is based on the discovery that a vascular stent or other implantable medical device can be coated with a biodegradable biocompatible polymer to which is attached a bioligand that specifically captures progenitors of endothelial cells (PECs) from the circulating blood to promote endogenous formation of healthy endothelium in Type II diabetics. In one embodiment, the bioligand is a peptide that specifically binds to an integrin receptor on PECs. The invention also provides methods for using such vascular stents and other implantable devices to promote vascular healing in Type II diabetics, for example following mechanical intervention. | 11-20-2008 |
20090068743 | CATIONIC ALPHA-AMINO ACID-CONTAINING BIODEGRADABLE POLYMER GENE TRANSFER COMPOSITIONS - The invention provides gene transfer compositions using as the gene carrier a biodegradable polymer that contains one or more cationic alpha amino acids, such as arginine or agmatine. The compositions form a tight soluble complex with a poly nucleic acid suitable for transfecting target cells to effect translation of the cargo poly nucleic acid by the target cell. Thus, such compounds are useful both in vitro and in vivo. | 03-12-2009 |
20110137406 | BIOACTIVE STENTS FOR TYPE II DIABETICS AND METHODS FOR USE THEREOF - The present invention is based on the discovery that a vascular stent or other implantable medical device can be coated with a biodegradable biocompatible polymer to which is attached a bioligand that specifically captures progenitors of endothelial cells (PECs) from the circulating blood to promote endogenous formation of healthy endothelium in Type II diabetics. In one embodiment, the bioligand is a peptide that specifically binds to an integrin receptor on PECs. The invention also provides methods for using such vascular stents and other implantable devices to promote vascular healing in Type II diabetics, for example following mechanical intervention. | 06-09-2011 |
Kristin M. James, Santa Barbara, CA US
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20160061917 | SELECTIVE SAMPLING MAGNETIC RESONANCE-BASED METHOD FOR ASSESSING STRUCTURAL SPATIAL FREQUENCIES - The disclosed embodiments provide a method for acquiring MR data at resolutions down to tens of microns for application in in-vivo diagnosis and monitoring of pathology for which changes in fine tissue textures can be used as markers of disease onset and progression. Bone diseases, tumors, neurologic diseases, and diseases involving fibrotic growth and/or destruction are all target pathologies. Further the technique can be used in any biologic or physical system for which very high-resolution characterization of fine scale morphology is needed. The method provides rapid acquisition of selected values in k-space, with multiple successive acquisitions of individual k-values taken on a time scale on the order of microseconds, within a defined tissue volume, and subsequent combination of the multiple measurements in such a way as to maximize SNR. The reduced acquisition volume, and acquisition of only select values in k-space along selected directions, enables much higher in-vivo resolution than is obtainable with current MRI techniques. | 03-03-2016 |
Kristin M. Leiferman, Salt Lake City, UT US
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20150132221 | METHODS FOR DIAGNOSING AND MONITORING EOSINOPHILIC ESOPHAGITIS - Disclosed are compositions and methods for diagnosing eosinophilic esophagitis in a subject. Also disclosed are methods for monitoring the course of eosinophilic esophagitis in a subject before, during, and after treatment. | 05-14-2015 |
Kristin M. Listner, East Windsor, NJ US
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20080274452 | Process For Large Scale Production Of Plasmid Dna By E.Coli Fermentation - The present invention relates generally to a method for increasing the yield of plasmid DNA production. The method includes the steps of selecting a highly productive clonal subtype of a strain of | 11-06-2008 |
20120190073 | PROCESS FOR LARGE SCALE PRODUCTION OF PLASMID DNA BY E. COLI FERMENTATION - The present invention relates generally to a method for increasing the yield of plasmid DNA production. The method includes the steps of selecting a highly productive clonal subtype of a strain of | 07-26-2012 |
Kristin M. Massoth, Prairie Village, KS US
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20090059730 | WATCH DEVICE HAVING TOUCH-BEZEL USER INTERFACE - A watch device includes a touch-sensitive user interface employing a sensor positioned within the bezel of the display for detecting when the bezel is touched by a user of the watch device. The sensor may be capable of detecting single presses, multiple simultaneous presses, and scrolling motion presses about the bezel. | 03-05-2009 |
20090295596 | SWIM WATCH - A watch device for use by a swimmer while swimming in a body of water. The watch device may generally comprise a housing, a location determining component disposed within the housing and operable to receive one or more satellite signals to determine a current geographic location of the housing, and a processing system. The processing system may synchronize the location determining component with the swimmer's arm movement so that the location determining component can determine the current geographic location of the housing. | 12-03-2009 |
20110128824 | SWIM WATCH - A watch device for use by a swimmer while swimming in a body of water. The watch device may generally comprise a housing, a location determining component disposed within the housing and operable to receive one or more satellite signals to determine a current geographic location of the housing, and a processing system. The processing system may synchronize the location determining component with the swimmer's arm movement so that the location determining component can determine the current geographic location of the housing. | 06-02-2011 |
20150120186 | DISTANCE CALIBRATION BY EVENT POINTS - An electronic device for tracking a distance traveled by a user along a course comprises a location determining element, a memory element, and a processing element. The location determining element is configured to receive location signals from a satellite-based positioning system and to determine a current geolocation of the user. The memory element is configured to store geolocations for a start point, an end point, and a plurality of intermediate event points that are passed by the user as he travels along the course, wherein each event point is positioned at a known distance from a stored geolocation such as the start point or another event point. The processing element is configured to determine a measured distance based on the current geolocation of the user and to determine a calibrated distance as a function of the measured distance and the known distances of the event points. | 04-30-2015 |
Kristin M. Pouw, Hamilton CA
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20090280429 | POLYESTER SYNTHESIS - The present disclosure provides for enzymatic polymerization to produce polyester resins suitable for use in manufacturing toners. | 11-12-2009 |
20100021839 | TONER COMPOSITIONS - Methods for modifying the acid value of an unsaturated polyester resin suitable for use in forming toner particles are provided. In embodiments, methods may include contacting at least one unsaturated polyester resin with at least one grafting monomer, polymerizing the graft monomer and unsaturated polyester resin to form a graft copolymer, and then utilizing the graft copolymer to form toner particles by combining the graft copolymer with an optional colorant, at least one surfactant, and an optional wax. Toners produced by these methods are also provided. | 01-28-2010 |
Kristin M. Warren, Pittsburgh, PA US
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20160122701 | Methods, Devices and Systems for Algae Lysis and Content Extraction - Described herein are devices, systems and methods for lysing algae cells, for production of a lysate product such as a biofuel. The systems and methods use a passive device that lyses the cells through flow configurations, geometries, and surfaces that would induce different stresses and negative pressure on the microalgae cells. When the stress is designed to exceed the mechanical strength of the microalgae cells, the cells are lysed, causing, e.g., lipid release which can be used to produce biofuels. Through an internally-created computational framework, the concept is validated and can be optimized for the lowest energy input with the highest level of lipid release. Also provided herein are computer-implemented methods for optimizing lysis in such systems and computer-readable media containing instructions for performing the computer-implemented methods. | 05-05-2016 |