Patent application number | Description | Published |
20150275643 | Location and Stimulation Methods and Apparatuses Utilizing Downhole Tools - A propellant tool for use in a hydrocarbon bearing formation. The tool includes a tubular body having a connector on each end for connection with other tubular members within a tubular string. A coded marker is positioned on the tubular body and a propellant chamber is positioned on an outside surface of the tubular body. A propellant ignition mechanism positioned on the tubular body for igniting the propellant in the propellant chamber. | 10-01-2015 |
20150275649 | Apparatus, Method, and System for Identifying, Locating, and Accessing Addresses of a Piping System - A method, system, and apparatus are described for locating, installing, inventorying, actuating, and/or accessing down-hole equipment in a wellbore. This comprises tagging a casing by inserting permanent components of material compositions within sections along the length of a casing. Inserted components and/or portions of an original section function as unique readable active and/or passive markers. The piping system comprises at least one pipe having a plurality of markers placed in radial sections strategically arranged with independently identical or different material compositions or embedded in a length of the wellbore casing. The sections function as markers forming a readable pattern readable by the reader(s). The reader is one of or a combination of any of the group consisting of: a plug, a probe, a sensor, and/or a computer for reading markers. The reader travels in either a forward or backward direction. | 10-01-2015 |
Patent application number | Description | Published |
20090089560 | INFRASTRUCTURE FOR PARALLEL PROGRAMMING OF CLUSTERS OF MACHINES - GridBatch provides an infrastructure framework that hides the complexities and burdens of developing logic and programming application that implement detail parallelized computations from programmers. A programmer may use GridBatch to implement parallelized computational operations that minimize network bandwidth requirements, and efficiently partition and coordinate computational processing in a multiprocessor configuration. GridBatch provides an effective and lightweight approach to rapidly build parallelized applications using economically viable multiprocessor configurations that achieve the highest performance results. | 04-02-2009 |
20100100767 | AUTOMATICALLY CONNECTING REMOTE NETWORK EQUIPMENT THROUGH A GRAPHICAL USER INTERFACE - Embodiments of the present invention provide a method and system for designing a test network in an integrated application, and configuring remote network devices through a network design application to test a network design. One embodiment of the present claimed subject matter is provided as a system for automatically configuring remote network devices to simulate a network connection. The system includes a plurality of computing devices which are physically coupled to one or more network devices, wherein the network devices are automatically configured to comprise a test network corresponding to a remote test network topology design. | 04-22-2010 |
20100287263 | METHOD AND SYSTEM FOR APPLICATION MIGRATION IN A CLOUD - A method and system for managing an application in a cloud data center by monitoring the bandwidth of a subnet of which the primary operating instance of an application is a member. If a severe deterioration in the bandwidth caused by an over consumption of the subnet resources from other subnet constituents is detected, a suitable secondary instance in an alternate, uncompromised subnet is located and primary operation of the application is transferred from the former primary operating instance to the secondary instance. The secondary instance can be pre-launched or dynamically requisitioned in the cloud data center. | 11-11-2010 |
20140359767 | METHOD AND SYSTEM FOR APPLICATION MIGRATION DUE TO DEGRADED QUALITY OF SERVICE - A method and system for managing an application in a cloud data center by monitoring the bandwidth of a subnet of which the primary operating instance of an application is a member. If a severe deterioration in the bandwidth caused by an over consumption of the subnet resources from other subnet constituents is detected, a suitable secondary instance in an alternate, uncompromised subnet is located and primary operation of the application is transferred from the former primary operating instance to the secondary instance. The secondary instance can be pre-launched or dynamically requisitioned according to various embodiments. | 12-04-2014 |
Patent application number | Description | Published |
20110067660 | ENGINE ROCKER ARM - A rocker arm may include a valve engagement region, a lift mechanism engagement region, a pivot region, and a body portion. The valve engagement region may be located at a first longitudinal end of the rocker arm and on a first side of the rocker arm. The lift mechanism engagement region may be located at a second longitudinal end of the rocker arm. The pivot region may be located between the valve engagement region and the lift mechanism engagement region and may define a rotational axis for the rocker arm. The body portion may extend longitudinally between and couple the valve engagement region, the pivot region and the lift mechanism engagement region to one another. The body portion may define first and second ribs on a second side of the rocker arm that extend longitudinally between the valve engagement region and the lift mechanism engagement region. | 03-24-2011 |
20110174260 | Internal Combustion Engine - A modular engine family comprises an engine block assembly having an upper end extending at an angle α from a rear of the engine block assembly to a front thereof. An engine block closes the upper end and defines a crankcase comprising a crankshaft having three journals supported by journal bearings for rotation therein. First and second piston pins and associated first and second piston/rod assemblies are disposed in piston cylinders of a first cylinder housing assembly wherein the first and second piston pins are located in the same radial position on the crankshaft and are spaced longitudinally to define a firing interval of 360 degrees. A cylinder head is configured to close open ends of the piston cylinders to thereby define combustion chambers with the first and second pistons; the cylinder housing assembly reclined from vertical towards the rear of the engine block by an angle β. | 07-21-2011 |
20120210958 | ENGINE ASSEMBLY INCLUDING CRANKSHAFT FOR V8 ARRANGEMENT - A crankshaft for a V8 engine includes first, second, third, fourth, fifth, sixth, seventh and eighth crank pins defined on the crankshaft. The second crank pin is rotationally offset from the first crank pin, the third crank pin is rotationally offset from the first and second crank pins, the fourth crank pin is rotationally offset from the first, second and third crank pins, the fifth crank pin is rotationally offset from the first, second, third and fourth crank pins, and the sixth pin is rotationally offset from the first, second, third, fourth and fifth crank pins. The seventh crank pin is rotationally aligned with the first crank pin and the eighth crank pin is rotationally aligned with the second crank pin. | 08-23-2012 |
20120234270 | ENGINE ASSEMBLY INCLUDING CRANKSHAFT FOR V4 ARRANGEMENT - An engine assembly may include an engine structure and a crankshaft. The engine structure may include an engine block defining a first bank of cylinders defining two cylinders and a second bank of cylinders defining two cylinders forming a V4 arrangement. The crankshaft may include a first crank pin, a second crank pin, a third crank pin and a fourth crank. The fourth crank pin may be rotationally offset from the first crank pin by a first angle of less than two hundred and seventy degrees in the rotational direction of the crankshaft. The second and third crank pins may be located rotationally between the first crank pin and the fourth crank pin in the rotational direction. | 09-20-2012 |
20140360459 | Reduced Torque Variation for Engines with Active Fuel Management - In one exemplary embodiment, a method for active fuel management in an engine having a plurality of cylinders is provided, the method including stopping a fuel flow into a first set of the plurality of cylinders, the stopping causing a deactivation of the first set of cylinders and continuing injection of fuel into a second set of the plurality of cylinders to provide power while the first set of cylinders are deactivated. The method also includes injecting gas into the first set of the plurality of cylinders when each of the first set of cylinders are at bottom dead center, the injected gas increasing a cylinder pressure in each of the first set of cylinders that reduces an amplitude of first order torque variations during operation of the engine while the first set of cylinders are deactivated. | 12-11-2014 |
Patent application number | Description | Published |
20140110454 | SURGICAL STAPLING APPARATUS INCLUDING SENSING MECHANISM - A surgical stapling device particularly suited for endoscopic procedures is described. The device includes a handle assembly and an elongated body extending distally from the handle assembly. The distal end of the elongated body is adapted to engage a disposable loading unit. A control rod having a proximal end operatively connected to the handle assembly includes a distal end extending through the elongated body. A control rod locking member is provided to prevent movement of the control rod until the disposable loading unit is fully secured to the elongated body of the stapling device. | 04-24-2014 |
20150090766 | Surgical Stapling Apparatus Including Sensing Mechanism - A surgical stapling device particularly suited for endoscopic procedures is described. The device includes a handle assembly and an elongated body extending distally from the handle assembly. The distal end of the elongated body is adapted to engage a disposable loading unit. A control rod having a proximal end operatively connected to the handle assembly includes a distal end extending through the elongated body. A control rod locking member is provided to prevent movement of the control rod until the disposable loading unit is fully secured to the elongated body of the stapling device. | 04-02-2015 |
20150173841 | Disposable Sterile Surgical Adaptor - A sterile adaptor, a sterile drape with the integrated sterile adaptor, and a telerobotic surgical system including the sterile drape are provided. The adaptor, drape, and system allow for draping portions of a telerobotic surgical system to maintain a sterile barrier between the sterile surgical field and the non-sterile robotic system while also providing an interface for transferring mechanical and electrical energy and signals between a robotic arm and a surgical instrument in the sterile field. | 06-25-2015 |
20150209041 | SURGICAL STAPLING APPARATUS INCLUDING SENSING MECHANISM - A surgical stapling device particularly suited for endoscopic procedures is described. The device includes a handle assembly and an elongated body extending distally from the handle assembly. The distal end of the elongated body is adapted to engage a disposable loading unit. A control rod having a proximal end operatively connected to the handle assembly includes a distal end extending through the elongated body. A control rod locking member is provided to prevent movement of the control rod until the disposable loading unit is fully secured to the elongated body of the stapling device. | 07-30-2015 |
Patent application number | Description | Published |
20090142308 | Methods for treating autoimmune disease by inducing autoantigen-specific regulatory CD4+ T cells - Described herein are methods and compositions for the treatment and monitoring the progress of autoimmune diseases. In some embodiments, the methods include the stimulation of regulatory T cells specific to autoantigens associated with the autoimmune disease. A specific embodiment relates to diabetes mellitus, and the prevention or delay of loss of residual β-cell mass, providing a longer remission period and delaying the onset of diabetes related, progressive, complications through immunotherapeutic induction of regulatory T cells specific for human insulin B chain. In addition, the methods described herein can be used to predict whether a subject, e.g., a subject with ongoing anti-insulin autoimmunity, will progress to T1DM, and to evaluate a subject's response to a therapeutic intervention. | 06-04-2009 |
20130315904 | COMBINATIONS OF MODALITIES FOR THE TREATMENT OF DIABETES - A method of treating, preventing, or delaying the progression of Type 1 diabetes mellitus by administering an effective amount of a fusion protein composition comprising a T-cell co-stimulation antagonist and a portion of an immunoglobulin molecule and an effective amount of a Type 1 diabetes autoantigen. The method includes, for example, administering a cytotoxic T-lymphocyte-associated antigen 4 (CTLA4) molecule and a Type 1 diabetes autoantigen. Pharmaceutical compositions are also provided herewith. | 11-28-2013 |
20130316375 | DIABETES BIOMARKERS - A new markers for insulin production decline in Type 1 diabetes has been found in the ratio the CD4 naïve (CD45RO-CD62L+) to central memory (CD45RO+CD62L+) and in the level of CD4 central memory T-cell subpopulations. A method of diagnosing autoimmunity and its progressiveness, more specifically diabetes, pre-diabetes, a susceptibility to diabetes mellitus, or the level of effectiveness of therapy/intervention modality for one or more of such conditions in a subject can be conducted by determining level of CD4 naïve (CD45RO-CD62L+) T-cells by immunofluorescence analysis of a sample extracted from a subject; determining level of CD4 central memory (CD45RO+CD62L+) T-cells by immunofluorescence analysis of a sample extracted from a subject, and quantitatively relating the levels of the CD4 naïve and central memory T-cells, wherein a low ratio of CD4 naïve T-cells to CD4 central memory T-cells and/or high CD4 central memory T-cell indicates autoimmunity, a susceptibility to autoimmunity, diabetes, pre-diabetes, a susceptibility to diabetes mellitus or ineffectiveness of a treatment for one or more of such conditions. | 11-28-2013 |
20140099306 | CTLA4 FUSION PROTEINS FOR THE TREATMENT OF DIABETES - A method of treating, preventing, or delaying the progression of Type 1 diabetes mellitus autoimmunity by administering an effective amount of a cytotoxic T-lymphocyte-associated antigen 4 (CTLA4) molecule is provided herewith. The CTLA4 molecule may be a fusion protein of a CTLA4 extracellular region and an immunoglobulin, such as abatacept. | 04-10-2014 |
20140220015 | COMBINATIONS OF MODALITIES FOR THE TREATMENT OF DIABETES - A method of treating, preventing, or delaying the progression of Type 1 diabetes mellitus by administering an effective amount of a fusion protein composition comprising a T-cell co-stimulation antagonist and a portion of an immunoglobulin molecule and an effective amount of a Type 1 diabetes autoantigen. The method includes, for example, administering a cytotoxic T-lymphocyte-associated antigen 4 (CTLA4) molecule and a Type 1 diabetes autoantigen. Pharmaceutical compositions are also provided herewith. | 08-07-2014 |
20150104451 | CTLA4 FUSION PROTEINS FOR THE TREATMENT OF DIABETES - A method of treating, preventing, or delaying the progression of Type 1 diabetes mellitus autoimmunity by administering an effective amount of a cytotoxic T-lymphocyte-associated antigen 4 (CTLA4) molecule is provided herewith. The CTLA4 molecule may be a fusion protein of a CTLA4 extracellular region and an immunoglobulin, such as abatacept. | 04-16-2015 |