Widder, US
Connor S. Widder, Austin, TX US
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20160052115 | TOOL FOR HOLDING COMPONENT - A tool for holding a component is provided. The tool includes a handle. The tool also includes an elongated body having a first end and a second end opposite to the first end. The tool further includes a holding assembly. The holding assembly is adapted to hold the component. The holding assembly includes a base portion. The base portion is connected to the second end of the elongated body. The base portion includes a first edge and a second edge opposite to the first edge. The holding assembly also includes a first arm. The first arm includes a first inner surface. The holding assembly further includes a second arm. The second arm includes a second inner surface. The first inner surface and the second inner surface face each other with a gap being defined there between. | 02-25-2016 |
David Widder, Sparks, NV US
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20100044435 | HANDHELD SCANNING DEVICE WITH TRIPLE DATA ACQUISITION FUNCTIONALITY - A handheld scanning device comprising a magnetic stripe reader, a bar code reader and an RFID reader. All three of the readers are integral to the device, and none of the readers needs to be removed in order to install any of the other readers. | 02-25-2010 |
Jeffrey M. Widder, Bel Air, MD US
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20140352188 | Caseless Projectile and Launching System - A launcher system includes a launcher having a barrel adapted to receive a projectile and a charge of propellant and a velocity variator configured to shift relative to barrel to selectively vary a launch velocity of projectile from launcher. The velocity variator may be constituted by a collar selectively controlling the propellant gases vented out of projectile and into barrel and/or a sliding breech face behind which is an energy-absorbing plug. | 12-04-2014 |
John A. Widder, Washougal, WA US
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20090168077 | High-resolution encoder array - A position sensing apparatus and method, motion control system, and integrated circuit are provided that include a plurality of sensors and a tracking processor. The plurality of sensors includes a linear array of sensors that sense a plurality of features of an object. A spacing between two of the plurality of sensors is substantially smaller than a spacing between two of the plurality of features. The tracking processor samples signals from the sensors, compares the samples to previous samples and calculates a position of the object. The plurality of sensors may include a second linear array of sensors. Centers of the sensors of the second linear array may be offset from centers of the sensors of the first linear array along a longitudinal axis of the plurality of sensors. | 07-02-2009 |
Kenneth Widder, San Diego, CA US
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20120288568 | METHODS AND COMPOSITIONS FOR TREATING OPHTHALMIC CONDITIONS VIA SERUM RETINOL, SERUM RETINOL BINDING PROTEIN (RBP), AND/OR SERUM RETINOL-RBP MODULATION - Compounds that reduce serum retinol, serum RBP, and/or serum retinol-RBP levels may be used to treat ophthalmic conditions associated with the overproduction of waste products that accumulate during the course of the visual cycle. We describe methods and compositions using such compounds and their derivatives to treat, for example, the macular degenerations and dystrophies or to alleviate symptoms associated with such ophthalmic conditions. Such compounds and their derivatives may be used as single agent therapy or in combination with other agents or therapies. | 11-15-2012 |
Kenneth Widder, Rancho Santa Fe, CA US
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20080254140 | Combination Methods and Therapies for Treating Opthalmic Conditions with 13-Cis-Retinyl Derivatives - Described herein are combination methods, compositions and therapies for treating ophthalmic conditions or diseases arising from, associated with or leading to the overproduction of waste products in the visual cycle. Agents included within these combinations are 13-cis-retinyl derivatives; other agents included within these combinations are selected from vitamins, antioxidants, minerals, inducers of nitric oxide production, anti-inflammatory agents, and negatively-charged phospholipids. Such combination methods may be used as single or multiple administration therapies, or in combination with other agents or therapies. | 10-16-2008 |
20090054532 | Modulators of Retinol-Retinol Binding Protein (RBP)-Transthyretin (TTR) Complex Formation - Described herein are methods and compositions for the detection of transthyretin (TTR), retinol binding protein (RBP) and retinol complex formation. The methods and compositions described herein also provide for the screening of modulators of retinol-RBP-TTR complex formation. Furthermore, the methods and compositions provide for therapeutic agents for the treatment and/or prevention of age-related macular degeneration and/or dystrophies. | 02-26-2009 |
20090253665 | METHOD OF TREATMENT OF DISEASE USING AN ADENOSINE A1 RECEPTOR ANTAGONIST AND AN ALDOSTERONE INHIBITOR - Pharmaceutical compositions comprising an aldosterone inhibitor and an adenosine A | 10-08-2009 |
20100298443 | METHODS AND COMPOSITIONS FOR TREATING OPHTHALMIC CONDITIONS WITH RETINYL DERIVATIVES - Compounds that cause reversible night blindness may be used to treat ophthalmic conditions associated with the overproduction of waste products that accumulate during the course of the visual cycle. We describe methods and compositions using such compounds and their derivatives to treat, for example, the macular degenerations and dystrophies or to alleviate symptoms associated with such ophthalmic conditions. Such compounds and their derivatives may be used as single agent therapy or in combination with other agents or therapies. | 11-25-2010 |
20110294891 | METHODS AND COMPOSITIONS FOR TREATING OPTHALMIC CONDITIONS WITH RETINOL DERIVATIVES - Compounds that cause reversible night blindness may be used to treat ophthalmic conditions associated with the overproduction of waste products that accumulate during the course of the visual cycle. We describe methods and compositions using such compounds and their derivatives to treat, for example, the macular degenerations and dystrophies or to alleviate symptoms associated with such ophthalmic conditions. Such compounds and their derivatives may be used as single agent therapy or in combination with other agents or therapies. | 12-01-2011 |
20120202885 | METHODS, ASSAYS AND COMPOSITIONS FOR TREATING RETINOL-RELATED DISEASES - Described herein are methods and compositions for treating certain retinol-related diseases and conditions by modulation of transthyretin (TTR) and retinol binding protein (RBP) availability in the subject. For example, the methods and compositions provide for therapeutic agents for the treatment and/or prevention of age-related macular degeneration and/or dystrophies, metabolic disorders, idiopathic intracranial hypertension, hyperostosis, and protein misfolding and aggregation diseases. The compositions disclosed may be used as single agent therapy or in combination with other agents or therapies. In addition, described herein are methods and assays for selecting appropriate agents that can modulate the TTR and RBP availability in a subject. | 08-09-2012 |
20120238632 | MODULATORS OF RETINOL-RETINOL BINDING PROTEIN (RBP)-TRANSTHYRETIN (TTR) COMPLEX FORMATION - Described herein are methods and compositions for the detection of transthyretin (TTR), retinol binding protein (RBP) and retinol complex formation. The methods and compositions described herein also provide for the screening of modulators of retinol-RBP-TTR complex formation. Furthermore, the methods and compositions provide for therapeutic agents for the treatment and/or prevention of age-related macular degeneration and/or dystrophies. | 09-20-2012 |
20120309835 | METHODS, ASSAYS AND COMPOSITIONS FOR TREATING RETINOL-RELATED DISEASES - Described herein are methods and compositions for treating certain retinol-related diseases and conditions by modulation of transthyretin (TTR) and retinol binding protein (RBP) availability in the subject. For example, the methods and compositions provide for therapeutic agents for the treatment and/or prevention of age-related macular degeneration and/or dystrophies, metabolic disorders, idiopathic intracranial hypertension, hyperostosis, and protein misfolding and aggregation diseases. The compositions disclosed may be used as single agent therapy or in combination with other agents or therapies. In addition, described herein are methods and assays for selecting appropriate agents that can modulate the TTR and RBP availability in a subject. | 12-06-2012 |
Kenneth J. Widder, Rancho Santa Fe, CA US
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20150366854 | OPHTHALMIC COMPOSITION - Provided herein is an ophthalmic composition. In some embodiments, the ophthalmic composition includes a low concentration of an ophthalmic agent for treatment of an ophthalmic disorder or condition; and an ophthalmically acceptable carrier, wherein the ophthalmic agent is distributed with substantial uniformity throughout the ophthalmically acceptable carrier. Further disclosed herein include an ophthalmic composition including a low concentration of an ophthalmic agent and deuterated water. Also disclosed herein are methods of arresting or preventing myopia development by administering to an eye of an individual in need thereof an effective amount of an ophthalmic composition as described herein. | 12-24-2015 |
Kenneth J. Widder, Rancho Sante Fe, CA US
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20090118334 | METHOD OF TREATMENT OF CARDIAC AND/OR RENAL FAILURE USING A CALCIUM CHANNEL BLOCKER AND AN ANGIOTENSIN CONVERTING ENZYME INHIBITOR OR AN ANGIOTENSIN II RECEPTOR BLOCKER - A pharmaceutical composition including a calcium channel blocker and an angiotensin II receptor blocker or an angiotensin converting enzyme inhibitor. Also disclosed is a method of treating cardiovascular disease or renal disease by identifying a patient in need of such treatment, and administering a pharmaceutical composition disclosed herein to said patient. | 05-07-2009 |
Laurie Widder, New York, NY US
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20150359227 | INSECT CONTROL DEVICE AND ASSOCIATED METHODS - Insect control devices and associated methods are generally described. In some embodiments, the insect control device includes one or more substrate materials impregnated or otherwise loaded with an active species (e.g., a pyrethroid). In some cases, the device may provide protection against insects over prolonged periods of time. | 12-17-2015 |
Mark W. Widder, Waynesboro, PA US
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20080262739 | Submersible Portable In-situ Automated Water Quality Biomonitoring Apparatus and Method - A submersible biomonitoring system for monitoring water quality in situ includes a submersible chamber constructed of a di-electric material and sized to allow suitable signals from one or more aquatic organisms to be received by eliminating cross-talk between cells while allowing ambient conditions to be maintained inside the chamber. The aquatic organism exhibits ventilatory behavior and body movement sensitive to water quality which manifest as electrical signals picked up by electrodes and communicated to a pre-amplifier that conditions the signals for communication to a land-based amplifier and/or controller that is used to interpret the signals to determine when the water to which the organism is exposed has caused physiological stress to the organism. | 10-23-2008 |
20120156715 | Environmental Sentinel Biomonitor System (ESB) - An embodiment of the invention provides a system for toxicity identification in water. The system includes a cell maintenance device having a cooling component that maintains an internal storage area of the cell maintenance device within a temperature range of 4 degrees Celsius to 25 degrees Celsius. Fluidic biochips in the cell maintenance device include one or more testing components for receiving living poikilothermic cells and at least one water test sample. A test unit receives the fluidic biochips and monitors a response to exposure of the poikilothermic cells to the water test sample. In at least one embodiment, the test unit is able to identify the degree of toxicity of the water sample within 60 minutes of receiving the fluidic biochip. | 06-21-2012 |