Yong, US
Albert Yong, Morrisville, NC US
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20130311735 | METHOD AND SYSTEM FOR PROVIDING SUBSTANTIALLY CONSTANT-TIME EXECUTION OF A COPY OPERATION - A system and method for providing a substantially constant-time copy operation for file system objects managed by a storage server begins by generating a snapshot of at least a portion of a data set managed by the storage server. The system then performs a copy operation in the storage server to generate a copy of the data set separate from the snapshot, on a set of block locations containing a predetermined reference value. During the copy operation to generate the copy of the data set separate from the snapshot, the system can receive from a requester a first read request directed to the copy of the data set that the copy operation is to generate. In response to the first data request, the system provides data from the snapshot to the requester by the storage server. | 11-21-2013 |
Albert E. Yong, Morrisville, NC US
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20140351464 | INCREASED CONCURRENCY OF AN INITIALIZATION PROCESS OF MULTIPLE DATA STORAGE UNITS OF A VOLUME - This disclosure uses both an administrative thread and multiple worker threads (N) to process the LUN on-lining work in parallel at both the volume level and the LUN level. When the administrative thread receives the message to start the initialization, the administrative thread assigns the work for reading the VTOC information for the LUNs in a volume to one or more worker threads and moves on to perform additional initialization tasks. N worker threads work on N volumes in parallel. These worker threads then independently send messages (e.g., asynchronous messages) to the file system layer, and once the file system layer is done loading the required buffers, the file system layer sends replies back to the administrative thread. The administrative thread then again assigns work to the worker threads to finally bring the LUNs on-line. | 11-27-2014 |
Ben Yong, Glenn Dale, MD US
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20130017545 | APPARATUS AND METHODS FOR ACQUIRING ANALYTES FROM A DRIED BIOLOGICAL FLUID SAMPLEAANM Yong; BenAACI Glenn DaleAAST MDAACO USAAGP Yong; Ben Glenn Dale MD USAANM Hudson; William C.AACI TustinAAST CAAACO USAAGP Hudson; William C. Tustin CA US - An apparatus for acquiring analytes from a dried biological fluid sample includes a tube, a substrate in a proximal section of the tube, and a sorbent bed in a distal section of the tube. A biological fluid sample is dispensed on the substrate and is dried to form a dried sample. A conditioning solvent is flowed into the distal section to condition the sorbent bed. A first elution solvent is flowed through the substrate and the sorbent bed. Analytes are eluted from the dried sample and retained on the sorbent bed. A second elution solvent is flowed through the substrate and the sorbent bed. The analytes are eluted from the sorbent bed, pass through an opening, and are collected. Alternatively, an elution solvent is flowed through the substrate and the sorbent bed such that analytes eluted from the dried sample pass through the sorbent bed and the opening for collection, while non-analytes are retained on the sorbent bed. | 01-17-2013 |
Chan-Loi Yong, Brookfield, CT US
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20110268700 | DOSAGE REGIMENS FOR HCV COMBINATION THERAPY - The present invention relates to therapeutic combinations comprising (a) Compound (1), or a pharmaceutically acceptable salt thereof, as herein described, (b) an interferon alfa and (c) ribavirin and particular regimens for administering this combination. Compound (1) is a selective and potent inhibitor of the HCV NS3 serine protease. The present invention also relates to methods of using such therapeutic combinations for treating HCV infection or alleviating one or more symptoms thereof in a patient. | 11-03-2011 |
Chin Yong, Austin, TX US
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20130301847 | SEQUENCED ADAPTATION OF ANTI-NOISE GENERATOR RESPONSE AND SECONDARY PATH RESPONSE IN AN ADAPTIVE NOISE CANCELING SYSTEM - A personal audio device, such as a wireless telephone, includes an adaptive noise canceling (ANC) circuit that adaptively generates an anti-noise signal from a reference microphone signal and injects the anti-noise signal into the speaker or other transducer output to cause cancellation of ambient audio sounds. An error microphone is also provided proximate to the speaker to provide an error signal indicative of the effectiveness of the noise cancellation. A secondary path estimating adaptive filter is used to estimate the electro-acoustical path from the noise canceling circuit through the transducer so that source audio can be removed from the error signal. Adaptation of adaptive filters is sequenced so that update of their coefficients does not cause instability or error in the update. A level of the source audio with respect to the ambient audio can be determined to determine whether the system may generate erroneous anti-noise and/or become unstable. | 11-14-2013 |
20130301848 | DOWNLINK TONE DETECTION AND ADAPTATION OF A SECONDARY PATH RESPONSE MODEL IN AN ADAPTIVE NOISE CANCELING SYSTEM - An adaptive noise canceling (ANC) circuit adaptively generates an anti-noise signal from a reference microphone signal that is injected into the speaker or other transducer output to cause cancellation of ambient audio sounds. An error microphone proximate the speaker provides an error signal. A secondary path estimating adaptive filter estimates the electro-acoustical path from the noise canceling circuit through the transducer so that source audio can be removed from the error signal. Tones in the source audio, such as remote ringtones, present in downlink audio during initiation of a telephone call, are detected by a tone detector using accumulated tone persistence and non-silence hangover counting, and adaptation of the secondary path estimating adaptive filter is halted to prevent adapting to the tones. Adaptation of the adaptive filters is then sequenced so any disruption of the secondary path adaptive filter response is removed before allowing the anti-noise generating filter to adapt. | 11-14-2013 |
20150269926 | SOURCE AUDIO ACOUSTIC LEAKAGE DETECTION AND MANAGEMENT IN AN ADAPTIVE NOISE CANCELING SYSTEM - A personal audio device, such as a wireless telephone, includes an adaptive noise canceling (ANC) circuit that adaptively generates an anti-noise signal from a reference microphone signal and injects the anti-noise signal into the speaker or other transducer output to cause cancellation of ambient audio sounds. An error microphone is also provided proximate to the speaker to provide an error signal indicative of the effectiveness of the noise cancellation. A secondary path estimating adaptive filter is used to estimate the electro-acoustical path from the noise canceling circuit through the transducer so that source audio can be removed from the error signal. A level of the source audio with respect to the ambient audio is determined to determine whether the system may generate erroneous anti-noise and/or become unstable. | 09-24-2015 |
Chin Huang Yong, Austin, TX US
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20140307888 | SYSTEMS AND METHODS FOR MULTI-MODE ADAPTIVE NOISE CANCELLATION FOR AUDIO HEADSETS - In accordance with the present disclosure, an integrated circuit for implementing at least a portion of a personal audio device may include an output and a processing circuit. The output may provide an output signal to a transducer including both a source audio signal for playback to a listener and an anti-noise signal for countering the effect of ambient audio sounds in an acoustic output of the transducer. The processing circuit may implement an adaptive noise cancellation system that generates the anti-noise signal to reduce the presence of the ambient audio sounds heard by the listener by adapting, based on a presence of the source audio signal, a response of the adaptive noise cancellation system to minimize the ambient audio sounds at the acoustic output of the transducer, wherein the adaptive noise cancellation system is configured to adapt both in the presence and the absence of the source audio signal. | 10-16-2014 |
20140314244 | SYSTEMS AND METHODS FOR ADAPTIVE NOISE CANCELLATION BY BIASING ANTI-NOISE LEVEL - A processing circuit may comprise an adaptive filter having a response generating an anti-noise signal from a reference microphone signal, a secondary path estimate filter modeling an electro-acoustic path of a source audio signal, a biasing portion that generates a scaled anti-noise signal by applying a scaling factor and the response of the secondary path estimate filter to the anti-noise signal, and a coefficient control block that shapes the response of the adaptive filter in conformity with the reference microphone signal and a modified playback corrected error signal by adapting the response of the adaptive filter to minimize ambient audio sounds in the error microphone signal, wherein the playback corrected error is based on a difference between the error microphone signal and the source audio signal and the modified playback corrected error signal is based on a difference between the playback corrected error signal and the scaled anti-noise signal. | 10-23-2014 |
Daniel Yong, Phoenix, AZ US
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20120191611 | SYSTEMS AND METHODS FOR ENCODED ALIAS BASED TRANSACTIONS - Disclosed is a computer based method for securing a financial transaction. A transaction device does not include any human readable data that can be used to identify the account owner and/or the transaction account. A first code and a second code are combined to determine an alias transaction account code. A transaction account is determined based upon the alias transaction account code. | 07-26-2012 |
20160055484 | SYSTEMS AND METHODS FOR ENCODED ALIAS BASED TRANSACTIONS - Disclosed is a computer based method for securing a financial transaction. A transaction device does not include any human readable data that can be used to identify the account owner and/or the transaction account. A first code and a second code are combined to determine an alias transaction account code. A transaction account is determined based upon the alias transaction account code. | 02-25-2016 |
Daniel W. Yong, Peoria, AZ US
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20130036058 | SYSTEMS AND METHODS FOR SECURELY PROCESSING TRANSACTIONS - This disclosure includes a system, method, and article of manufacture for securely processing a transaction. The method may comprise performing a three factor authentication, communicating and/or generating, to a web client, a token in response to a transaction request and based upon the three factor authentication, comparing the token to a received token, and authorizing the transaction request based upon the comparing. Three factor authentication may comprise authenticating a web client to a transaction account associated with an individual, authenticating a web client to a payment network associated with the transaction account, and authenticating an individual to the transaction account based upon a biometric sample. | 02-07-2013 |
David Yong, New York, NY US
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20080262878 | SYSTEMS, METHODS, AND COMPUTER PROGRAM PRODUCTS FOR GENERATING AND UPDATING A CACHE OF PRICE AND AVAILABILITY INFORMATION FOR TRAVEL PACKAGES AND COMPONENTS - Systems, methods, and computer program products are provided for generating, updating, and managing a cache of price and availability information for a plurality of travel packages and components. The cache of price and availability information may then be searched by an online travel planning service to provide customers with a list of available travel products. More particularly, embodiments of the present invention provide a cascading cache system including a cache of price and availability data related to travel components and a cache of price and availability data related to travel packages. Changes made to the component cache can affect information stored in the package cache, and changes made to the package cache can affect information stored in the component cache. Furthermore, the cache system updates the package and component caches based on information received from a purchase of a package or component, as well as by proactively polling one or more travel reservation systems. | 10-23-2008 |
Gideon Yong, Minneapolis, MN US
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20120038404 | DUTY CYCLE BASED PHASE INTERPOLATORS AND METHODS FOR USE - Duty cycle based phase interpolators, and methods for implementing duty cycle based phase interpolators are disclosed. One such phase interpolator includes a first pulse width modulator configured to generate a first duty cycle signal, and a second pulse width modulator configured to generate a second duty cycle signal. The phase interpolator further includes a logic unit configured to merge the first duty cycle signal and the second duty cycle signal to produce a periodic digital signal with a controllable phase depending on the first and second duty cycle signals. | 02-16-2012 |
20120326750 | DUTY CYCLE BASED PHASE INTERPOLATORS AND METHODS FOR USE - Duty cycle based phase interpolators, and methods for implementing duty cycle based phase interpolators are disclosed. One such phase interpolator includes a first pulse width modulator configured to generate a first duty cycle signal, and a second pulse width modulator configured to generate a second duty cycle signal. The phase interpolator further includes a logic unit configured to merge the first duty cycle signal and the second duty cycle signal to produce a periodic digital signal with a controllable phase depending on the first and second duty cycle signals. | 12-27-2012 |
Hong Yong, Grayslake, IL US
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20100190822 | Pharmaceutical Compositions As Inhibitors of Dipeptidyl Peptidase-IV (DPP-IV) - The present invention relates to compounds which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, Syndrome X, hyperinsulinemia, obesity, atherosclerosis, and various immunomodulatory diseases. | 07-29-2010 |
20130059873 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) - The present invention relates to compounds which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, Syndrome X, hyperinsulinemia, obesity, atherosclerosis, and various immunomodulatory diseases. | 03-07-2013 |
Hong Yong, Libertyville, IL US
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20090054426 | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS - A method for treating a patient suffering from disorders and deficits of the central nervous system associated with diabetes, associated with aging and neurodegeneration, comprising attention deficit disorder in general, attention deficit hyperactivity disorder (ADHD), Alzheimer's disease (AD), mild cognitive impairment, senile dementia, AIDS dementia, neurodegeneration, depression, and schizophrenia, comprising administering to a patient in need of such treatment an effective amount of a selective inhibitor of the 11-β-hydroxysteroid dehydrogenase Type 1 enzyme activity. | 02-26-2009 |
20090131434 | Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme - The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action. | 05-21-2009 |
20090176783 | INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME - The present invention relates to inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme and their use in treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, central nervous system disorders, and diseases and conditions that are related to excessive glucocorticoids. | 07-09-2009 |
20090192141 | METHODS OF USE OF INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME - The present invention relates to inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme and their use in treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, central nervous system disorders, and diseases and conditions that are related to excessive glucocorticoids. | 07-30-2009 |
20090192198 | INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME - The present invention relates to inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme and their use in treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, central nervous system disorders, and diseases and conditions that are related to excessive glucocorticoids. | 07-30-2009 |
20100152179 | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS - A method for treating a patient suffering from disorders and deficits of the central nervous system associated with diabetes, associated with aging and neurodegeneration, comprising attention deficit disorder in general, attention deficit hyperactivity disorder (ADHD), Alzheimer's disease (AD), mild cognitive impairment, senile dementia, AIDS dementia, neurodegeneration, depression, and schizophrenia, comprising administering to a patient in need of such treatment an effective amount of a selective inhibitor of the 11-β-hydroxysteroid dehydrogenase Type 1 enzyme activity. | 06-17-2010 |
20110218214 | Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme - The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action. | 09-08-2011 |
20120289512 | Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme - The present invention relates to inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme and their use in treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, central nervous system disorders, and diseases and conditions that are related to excessive glucocorticoids. | 11-15-2012 |
20130045978 | INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME - The present invention relates to inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme and their use in treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, central nervous system disorders, and diseases and conditions that are related to excessive glucocorticoids. | 02-21-2013 |
20130059829 | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS - A method for treating a patient suffering from disorders and deficits of the central nervous system associated with diabetes, associated with aging and neurodegeneration, comprising attention deficit disorder in general, attention deficit hyperactivity disorder (ADHD), Alzheimer's disease (AD), mild cognitive impairment, senile dementia, AIDS dementia, neurodegeneration, depression, and schizophrenia, comprising administering to a patient in need of such treatment an effective amount of a selective inhibitor of the 11-β-hydroxysteroid dehydrogenase Type 1 enzyme activity. | 03-07-2013 |
20130338169 | METHODS OF USE OF INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME - The present invention relates to inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme and their use in treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, central nervous system disorders, and diseases and conditions that are related to excessive glucocorticoids. | 12-19-2013 |
20150065508 | INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME - The present invention relates to inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme and their use in treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, central nervous system disorders, and diseases and conditions that are related to excessive glucocorticoids. | 03-05-2015 |
20150099740 | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS - A method for treating a patient suffering from disorders and deficits of the central nervous system associated with diabetes, associated with aging and neurodegeneration, comprising attention deficit disorder in general, attention deficit hyperactivity disorder (ADHD), Alzheimer's disease (AD), mild cognitive impairment, senile dementia, AIDS dementia, neurodegeneration, depression, and schizophrenia, comprising administering to a patient in need of such treatment an effective amount of a selective inhibitor of the 11-β-hydroxysteroid dehydrogenase Type 1 enzyme activity. | 04-09-2015 |
20150265613 | INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME - The present invention relates to inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme and their use in treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, central nervous system disorders, and diseases and conditions that are related to excessive glucocorticoids. | 09-24-2015 |
Jackie S. Yong, Phillipsburg, NJ US
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20150101062 | SYSTEM AND METHOD FOR ONLINE DATA PROCESSING - Customer online data is collected via script on customer computers and is communicated to a server hosted by an organization, such as a card issuer. The customer online data communicated to the server is non-personally identifiable information (non-PII). In turn, the server aggregates the non-PII customer online data from the set of participating merchants. The server associates the received non-PII customer online data with non-PII demographic data. Other non-PII transaction data, such as previous transactions processed at a card issuer, also can be associated with the non-PII customer online data and non-PII demographic data. These associations are, in turn, used to create reports and to provide services to help merchants or other requesting organizations develop online strategies to drive click thru and conversion rates. | 04-09-2015 |
Jeongsik Yong, Broomall, PA US
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20120252718 | Compositions and Methods for Regulating Cytochrome c-Mediated Apoptosis by tRNA - The invention relates to the discovery that tRNA is a potent regulator of cell survival, tRNA regulates the interaction between cytochrome c and Apaf-1 and subsequently Apaf-1 oligomerization into an apoptosome which in turn recruits and oligomerizes the caspase cascade which ultimately leads to cell death. Accordingly, the present invention provides compositions and methods for regulating cell survival. | 10-04-2012 |
20150197729 | Compositions and Methods for Regulating Cytochrome c-Mediated Apoptosis by tRNA - The invention relates to the discovery that tRNA is a potent regulator of cell survival. tRNA regulates the interaction between cytochrome c and Apaf-1 and subsequently Apaf-1 oligomerization into an apoptosome which in turn recruits and oligomerizes the caspase cascade which ultimately leads to cell death. Accordingly, the present invention provides compositions and methods for regulating cell survival. | 07-16-2015 |
Jinloong Yong, Watertown, CT US
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20090098763 | Contacts For Use In Monitoring Connection Patterns In Data Ports - A telecommunications connection system including a plug; an outlet; the plug including: a plug body; transmission contacts supported in the plug body, the transmission contacts transmitting signals when the plug is mated with the outlet; a plug contact mounted on the plug body, the plug contact deflecting towards the plug body upon mating the plug with the outlet, the plug contact carrying a connectivity signal for monitoring port-to-port connectivity; a conductor in electrical connection with the plug contact; an outlet contact for making contact with the plug contact for transmission of the connectivity signal; outlet transmission contacts in the outlet making electrical contact with the transmission contacts. | 04-16-2009 |
Joe Cheow Chao Yong, Bellevue, WA US
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20160125015 | DATABASE DATA DISTRIBUTION MANAGEMENT - The maintaining of a database that is distributed across a front database and one or more cloud databases. Rather than have the front and remote portions of the database be fixed, a data distribution manager evaluates databases segments following a data distribution policy to identify one or more database segments that are to be transferred to or from the one or more cloud databases from or to the front database. In response, the data distribution manager causes the identified database segment to be moved. Accordingly, the data that is in the front database (and the data that is stored in the cloud) may vary over time. | 05-05-2016 |
Jun Xian Yong US
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20110130019 | ELECTRICAL CONNECTOR AND ELECTRICAL CONNECTOR ASSEMBLY - An electrical connector comprises a dielectric body, a plurality of terminals, and a metal shell. The dielectric body includes a base and a tongue. The tongue extends forward from the base and supports the plurality of terminals. The metal shell is integrally formed around the dielectric body, and can be formed by bending a metal plate, and includes a top wall, a bottom wall opposite to the top wall, a first side wall, and a second side wall, the four walls defining a rectangular opening. The first side wall includes a lower wall portion and an upper wall portion, both of which are joined at a seam on the first side wall. The lower wall portion has a lower solder leg and the upper wall portion has an upper solder leg and the lower and upper solder legs can be soldered to the circuit board. | 06-02-2011 |
Kelvin Yong, Lyndhurst, NJ US
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20130274463 | PROCESS AND INTERMEDIATES FOR PREPARING MACROLACTAMS - The present invention relates to macrolactam compounds, intermediates useful in the preparation of macrolactams, methods for preparing the intermediates, and methods for preparing and modifying macrolactams. One use of the compounds and methods described herein is in the production of macrolactam compounds able to inhibit HCV NS3 protease activity. An example of an HCV inhibitory compound that can be synthesized using the procedures described herein is Compound A and derivative thereof. | 10-17-2013 |
20130331597 | AMIDATION PROCESS - This invention describes an amidation process whereby perfluorinated amino acids can be activated and treated with an amine in the presence of a coupling agent and a pyridine derivative to yield amides, without loss of optical purity. | 12-12-2013 |
Kelvin Yong, Westfield, NJ US
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20160075645 | AMIDATION PROCESS - This invention describes an amidation process whereby perfluorinated amino acids can be activated and treated with an amine in the presence of a coupling agent and a pyridine derivative to yield amides, without loss of optical purity. | 03-17-2016 |
Kelvin H. Yong, Lyndhurst, NJ US
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20100137597 | SYNTHESIS Of DIETHYLPHOSPHONATE - This application discloses a novel process for the preparation of phosphonate esters useful as intermediates in the preparation of himbacine analogs, themselves useful as thrombin receptor antagonists. The chemistry taught herein can be exemplified by the following scheme: | 06-03-2010 |
20100324295 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED 5-QUINOLYL-OXAZOLES AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF - The present invention relates a process for the preparation of a compound of the formula: | 12-23-2010 |
20110124867 | Process and intermediates for the Synthesis of heterocyclic Substituted Piperazines with CXCR3 Antagonist Activity - The present invention relates to novel processes for the preparation of the compound of the Formula A45: | 05-26-2011 |
Kelvin Hin-Yeong Yong, Westfield, NJ US
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20150210650 | SOLID FORMS OF 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRI- MIDINE-5-CARBOXAMIDE, COMPOSITIONS THEREOF AND METHODS OF THEIR USE - Provided herein are formulations, processes, solid forms and methods of use relating to 2-(tert-butylamino)-4-((1R,3R,4R)-3-hydroxy-4-methylcyclohexylamino)-pyrimidine-5-carboxamide. | 07-30-2015 |
Kelvin H.y. Yong, Westfield, NJ US
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20140081032 | PROCESSES FOR THE PREPARATION OF ISOINDOLE COMPOUNDS AND ISOTOPOLOGUES THEREOF - Processes for the preparation of certain isoindole compounds, and isotopologues thereof, are provided. In some embodiments, the processes comprise catalytic assymetrical hydrogenation with hydrogen gas or deuterium gas in a solvent containing exchangeable proton or deuterium for proton-deuterium exchange. | 03-20-2014 |
20150183739 | PROCESSES FOR THE PREPARATION OF ISOINDOLE COMPOUNDS AND ISOTOPOLOGUES THEREOF - Processes for the preparation of certain isoindole compounds, and isotopologues thereof, are provided. In some embodiments, the processes comprise catalytic assymetrical hydrogenation with hydrogen gas or deuterium gas in a solvent containing exchangeable proton or deuterium for proton-deuterium exchange. | 07-02-2015 |
Ken-Tye Yong, Tonawanda, NY US
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20100125100 | GOLD NANOROD-siRNA COMPLEXES AND METHODS OF USING SAME - Provided are methods and compositions for inhibiting expression of one or more target genes. The compositions contain RNA polynucleotides that can inhibit expression of a target gene via RNA interference (RNAi) electrostatically complexed with surface functionalized gold nanorods (GNRs). The RNA polynucleotides are not covalently bound to the surface functionalized GNRs. The method involves inhibiting expression of a target gene in an individual. The method is performed by administering to the individual an effective amount of a composition containing surface functionalized GNRs electrostatically complexed with RNA polynucleotides, such as siRNA, that can inhibit expression of the target gene via RNAi. The siRNA is not covalently bound to the surface functionalized GNRs. | 05-20-2010 |
Lucy Yong, Georgetown, TX US
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20140086253 | Overlay Virtual Gateway for Overlay Networks - A method for providing communication over an overlay virtual network (OVN) with multiple data plane encapsulations at a tunnel endpoint comprising receiving a data packet via a first overlay tunnel, wherein the data packet comprises an encapsulation header of a first encapsulation type and an inner destination address, determining an egress tunnel endpoint and a second encapsulation type supported by the egress tunnel end point based on the inner destination address, performing encapsulation translation on the data packet by replacing the encapsulation header of the first encapsulation type with an encapsulation header of the second encapsulation type to form a translated packet, and forwarding the translated packet toward the egress tunnel endpoint via a second overlay tunnel, wherein the first encapsulation type and the second encapsulation type are different encapsulation types, and wherein the data packet is destined to the egress tunnel endpoint. | 03-27-2014 |
20140233569 | Distributed Gateway in Virtual Overlay Networks - A method for distributing the inter-network forwarding policies to a distributed gateway located within a network virtualization edge (NVE). The NVE may receive a data packet within a first virtual overlay network and determine that the data packet is destined for a destination end point located within a second virtual overlay network. The NVE may validate the data packet corresponds to an inter-network forwarding policy stored within the distributed gateway and forward the data packet to the second virtual overlay network. Alternatively, the NVE may forward the data packet toward a gateway or query the corresponding policy from a controller if no corresponding inter-network forwarding policy is located on the distributed gateway. A distributed gateway may receive the forwarding policies from a designated gateway or from a centralized controller. | 08-21-2014 |
20140307744 | Service Chain Policy for Distributed Gateways in Virtual Overlay Networks - A method forwarding data traffic based on a service chain policy for distributed gateway located within a network virtualization edge (NVE). The NVE may receive, within a first virtual overlay network, a data packet destined for a destination tenant end point located in a second virtual overlay network. The NVE may determine that a network service function is unavailable to treat the data packet between the first virtual overlay network and the second virtual overlay network. In order to route the data packet, the NVE may obtain a service chain policy that provides the location of a network node configured to treat the data packet with the network service function. The NVE may transmit the data packet toward the network node. A service chain policy may correspond to a sequence of network nodes that represents a path to the destination tenant end point. | 10-16-2014 |
20150055652 | Multi-Destination Traffic Control in Multi-Level Networks - An internet protocol (IP) traffic control method comprising receiving a message that comprises multicast group information and distribution tree root information from a tree root node in a first network area, determining the border network node is a designated forwarder for the second network area, sending an announcement message that comprises the multicast group information and the distribution tree root information within the second network area, receiving multicast group membership information for a multicast group computing a multicast group membership summary for the first network area and the second network area, sending the multicast group membership summary to first network area and the second network area, computing a distribution tree using the multicast group information and the distribution tree root information, pruning the distribution tree to generate a multicast tree, and communicating multicast data traffic between the first network area and the second network area along the multicast tree. | 02-26-2015 |
20150195197 | Service Function Chaining in a Packet Network - Service function chaining is a sequence of service function instances that traffic flows need to traverse through in order. Those service function instances are not required to reside on the direct path and traffic flow, but steered through network nodes. Service function instances and network nodes process the packets that carry a service function chain (SFC) header. The packets are encapsulated by a virtual network overlay header and forwarded through the service function instances in an SFC. The SFC header in specific format will prompt the network nodes to re-route the packets in the traffic flow using destination based forwarding or path based forwarding method in the packet network as well as an SDN controller and/or in-band control plane, and able to carry the metadata with the packets. | 07-09-2015 |
20160080246 | Offloading Tenant Traffic in Virtual Networks - An apparatus comprising a receiver configured to receive an offload traffic notification from tenant service system, and a processor coupled to a memory and the receiver, where the memory comprises computer executable instructions stored in a non-transitory computer readable medium, that when executed by the processor, cause the processor to receive the offload traffic notification, wherein the offload traffic notification identifies a sender tenant system and a receiver tenant system and comprises policy information, determine a network mapping between a network virtualization edge (NVE) that is associated with the receiver tenant system and the receiver tenant system, generate a network mapping message that comprises the network mapping, and send the network mapping message and policy information within a network to an NVE that is associated with a sender tenant system. | 03-17-2016 |
20160119159 | Bit Index Explicit Replication Forwarding Using Replication Cache - A data packet forwarding method including receiving, by a network node, a data packet that comprises a bit string, a BFIR identifier (ID), and a multicast replication path (MRP) ID, wherein the BFIR ID identifies an ingress network node for a multicast group, and wherein the MRP ID identifies the multicast group, identifying an entry in a BIER Replication Path Cache Table (BRCT) using the BFIR ID and the MRP ID, wherein the entry identifies a replication neighbor (NBR) list associated with the BFIR ID and the MRP ID, and forwarding the data packet in accordance with the replication NBR list. | 04-28-2016 |
Luo Yong, Plymouth, MN US
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20140204485 | WRITE POLE BOX SHIELD - A magnetic element may be generally configured as a data writer constructed at least with a write pole within a box shield that consists of first and second side shields and first and second vertical shields. The write pole may be separated from the box shield by a multi-layer gap structure that consists of at least two gap layers of dissimilar materials. | 07-24-2014 |
Mei Yong, Acton, MA US
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20100098149 | SYSTEMS AND METHODS FOR MULTICARRIER MODULATION USING MULTI-TAP FREQUENCY-DOMAIN EQUALIZER AND DECISION FEEDBACK - Through the use of feedback in determining frequency domain equalization, interference can be reduced. Specifically, the determined constellation point closest to the determined received point can be fed back to aid in determining one or more other closest constellation points. | 04-22-2010 |
20100296570 | SYSTEMS AND METHODS FOR MULTICARRIER MODULATION USING MULTI-TAP FREQUENCY-DOMAIN EQUALIZER AND DECISION FEEDBACK - Through the use of feedback in determining frequency domain equalization, intersymbol interference can be reduced. Specifically, the determined constellation point closest to the determined received point can be fed back to aid in determining one or more other closest constellation points. | 11-25-2010 |
Nansil Yong, New York, NY US
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20130117902 | EXTENDABLE SHIRT COLLAR - An expandable shirt collar includes a pair of expandable collar members that are received within corresponding pockets at ends of a collarband. The collar members have fastening means associated therewith to permit closing of the collar. | 05-16-2013 |
Sandro L. Yong, Cleveland, OH US
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20100029639 | ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF - Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia. | 02-04-2010 |
20100056603 | ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF - Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia. | 03-04-2010 |
20110207730 | ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF - Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia. | 08-25-2011 |
20130171077 | ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF - Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia. | 07-04-2013 |
20140314685 | ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF - Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia. | 10-23-2014 |
Shiung-Vei Yong, Sammamish, WA US
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20130067539 | ACCESS CONTROL MANAGEMENT - The subject disclosure relates to authorization based on a determination of permissions that can be granted for an action(s) to be performed on a resource. The determination of the permission is based on a set of rules that represent a theory including a notion of trust that has been divided into different sized tables. The tables are utilized to evaluate two or more input claims and to facilitate a determination of whether access to at least one system resource is to be granted. The evaluation can include matching the two or more input claims to rows in the table, wherein access is allowed if a match is found. | 03-14-2013 |
Suksoon Yong, Austin, TX US
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20160098332 | DYNAMIC MULTI-PURPOSE EXTERNAL ACCESS POINTS CONNECTED TO CORE INTERFACES WITHIN A SYSTEM ON CHIP (SOC) - An integrated circuit device comprises multiple cores each comprising one or more separate input and output interfaces, the multiple cores integrated within the integrated circuit device to function as a single computer system. Internal inter-chip connection links are disposed on the integrated circuit device for connecting one or more cores with at least one other core via the one or more separate input and output interfaces. One or more bidirectional access ports are communicatively connected in each path of the inter-chip connection links to enable a separate external access point to each of the one or more separate input and output interfaces of the cores, wherein each of the one or more bidirectional access ports is dynamically selectable as each of an external input interface of the integrated circuit device and an external output interface of the integrated circuit device. | 04-07-2016 |
Yawfui Yong, Iowa City, IA US
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20110060150 | METHOD OF DETECTING FLUORESCENCE - The invention provides novel anthraquinone compositions that are useful as broad-spectrum quenchers of fluorescence and provides methods for making and using them. The anthraquinone quenchers can be conjugated to a variety of biologically relevant compounds, including lipids, nucleic acids, polypeptides, and more specifically antigens, steroids, vitamins, drugs, haptens, metabolites, toxins, environmental pollutants, amino acids, peptides, proteins, nucleotides, oligonucleotides, polynucleotides, carbohydrates, and their analogs. The invention also provides kits comprising, in one or more containers, at least one anthraquinone quencher dye composition of the present invention, and instructions for using that composition. | 03-10-2011 |
Yawfui Yong, Coralville, IA US
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20090053821 | FLUORESCENCE QUENCHING AZO DYES, THEIR METHODS OF PREPARATION AND USE - Disclosed is a group of azo quencher compositions useful as fluorescence quenchers having the general structure of formula 1, methods of making or using the compositions, and kits comprising the composition. | 02-26-2009 |
20090118482 | COMPOUNDS AND METHODS FOR LABELING OLIGONUCLEOTIDES - The invention provides a novel method of labeling oligonucleotides, with reporter moieties, including but not limited to, quenchers, fluorophores, biotin, digoxigenin, peptides and proteins. In addition, this invention provides a method of detecting hybridization of oligonucleotides. This invention also provides novel azo quenchers having the general formula shown below. | 05-07-2009 |
20090299041 | COMPOUNDS AND METHODS FOR LABELING OLIGONUCLEOTIDES - The invention provides a novel method of labeling oligonucleotides, with reporter moieties, including but not limited to, quenchers, fluorophores, biotin, digoxigenin, peptides and proteins. In addition, this invention provides a method of detecting hybridization of oligonucleotides. This invention also provides novel azo quenchers having the general formula shown below. | 12-03-2009 |
20100076181 | COMPOUNDS AND METHODS FOR LABELING OLIGONUCLEOTIDES - The invention provides a novel method of labeling oligonucleotides, with reporter moieties, including but not limited to, quenchers, fluorophores, biotin, digoxigenin, peptides and proteins. In addition, this invention provides a method of detecting hybridization of oligonucleotides. This invention also provides novel azo quenchers having the general formula shown below. | 03-25-2010 |
20100298554 | COMPOUNDS AND METHODS FOR LABELING OLIGONUCLEOTIDES - A compound having the general formula shown below: | 11-25-2010 |
20110319606 | COMPOUNDS AND METHODS FOR LABELING OLIGONUCLEOTIDES - A compound having the general formula shown below: | 12-29-2011 |
20120064633 | FLUORESCENCE QUENCHING AZO DYES, THEIR METHODS OF PREPARATION AND USE - Disclosed is a group of azo quencher compositions useful as fluorescence quenchers having the general structure of formula 1, methods of making or using the compositions, and kits comprising the composition. | 03-15-2012 |
20130116415 | FLUORESCENCE QUENCHING AZO DYES, THEIR METHODS OF PREPARATION AND USE - Disclosed is a group of azo quencher compositions useful as fluorescence quenchers having the general structure of formula 1, methods of making or using the compositions, and kits comprising the composition. | 05-09-2013 |
Yawfui Yong, Hamden, CT US
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20110293529 | FLUORESCENT NIRF ACTIVATABLE PROBES FOR DISEASE DETECTION - Fluorescent activatable probes for imaging biological processes and disease detection in vitro and in vivo. There is also described a method for detecting the presence of an enzyme. A sample is contacted with a nanoparticle including a monomer, at least one cleavable spacer comprising at least one fluorescence activation site, and at least two dyes of at least two types. The cleavable spacer is attached at one end to the nanoparticle. The at least two types comprise an energy donor type and an energy acceptor type. At least one dye of one type is embedded in the nanoparticle and the cleavable spacer has at least one dye of the other type attached. The at least two dyes comprise at least one matched pair capable of fluorescence resonance energy transfer. Fluorescence is detected by exposing the sample to a light source, and detecting emitted light with a detector. | 12-01-2011 |
Yook-Kong Yong, Princeton, NJ US
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20080289418 | ANGULAR VELOCITY SENSOR - An angular velocity sensor includes a protrusion protruding in a Y′-axis direction and extending in an X-axis direction on a main surface of a rotated Y cut quartz plate, and an excitation electrode and a detection electrode formed on the main surface adjacent to this protrusion. This excitation electrode excites thickness-shear vibration in the X-axis direction on the quartz substrate, exiting vibration on the protrusion. Then, the protrusion is bent and displaced due to Coriolis force acting in a direction orthogonal to the vibration of the protrusion corresponding to a rotation around an Y′ axis. This displacement at the protrusion is applied to the quartz substrate as stress. The detection electrode detects change of this stress, thereby angular speed added to the angular velocity sensor is detected. | 11-27-2008 |
20140347138 | METHODS FOR NOISE REDUCTION AND QUALITY FACTOR IMPROVEMENT IN RESONATORS - A low phase noise dual mode resonator and a method of making and using said resonator is disclosed. The dual mode resonator is capable of sustaining two frequency vibration modes simultaneously. The two frequency vibration modes are capable of exhibit non-linear coupling when one is driven at a higher voltage than the other. The dual mode resonator is configured such that the ratio of the two vibration frequency modes is a value that maximizes the non-linear coupling effect. As a result of the non-linear effect, the phase noise on the mode that is not overdriven is reduced. | 11-27-2014 |