Del Valle
David Del Valle, Austin, TX US
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20090054411 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS - The invention relates to chemical compounds of formula IA or IB: | 02-26-2009 |
20090270450 | CHEMICAL COMPOUNDS - The invention relates to chemical compounds of formula (I): | 10-29-2009 |
Edmundo David Del Valle, Tucson, AZ US
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20120264127 | SIMULTANEOUS DETECTION OF MUTATIONAL STATUS AND GENE COPY NUMBER - The present invention provides compositions and methods for simultaneously detecting mutational status and gene copy number. In particular, the present invention provides simultaneous measurement of gene copy number and detection of the L858R and Exon 19 del mutations in a tissue sample. | 10-18-2012 |
Edward M. Del Valle, Glendale Heights, IL US
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20140049004 | HAND PERSPIRATION REMOVAL DEVICE - A hand perspiration removal device comprises a base which includes top and bottom surfaces, a perspiration absorbing pad which is removably attached to the top surface, and an arrangement for securing the base to a part of a user's body. The bottom surface of the base comprises a concave configuration which extends from a first side of the base to a second, opposite side of the base such that the bottom surface is configured to conform to the part of the user's body to which the device is secured. | 02-20-2014 |
Frank Del Valle, Croton On Hudson, NY US
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20100109332 | Floating electricity generating plant - The purpose of this invention is to produce Electricity from running surface water by the use of a water wheel mounted on a Floating platform and coupled to a Generator assembly. The invention specifically uses already known technologies and existing equipment, in a novel combination to create a versatile floating power plant. | 05-06-2010 |
Juan R. Del Valle, Tampa, FL US
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20160083361 | INHIBITORS OF THE IRE-1/XBP-1 PATHWAY AND METHODS OF USING THEREOF - Disclosed are XBP-1/IRE-1 inhibitors having formula disclosed herein. Methods of making and using these inhibitors for the treatment of cancer, in particular B cell cancers, are also disclosed. Also disclosed is a genetic XBP-1-knockout cancer mouse model. In still further aspects, the disclosed subject matter relates to methods for treating oncological and inflammatory disorders in a patient. For example, disclosed herein are methods whereby an effective amount of a compound or composition disclosed herein is administered to a patient having an oncological disorder, for example B-cell chronic lymphocytic leukemia (CLL), and who is in need of treatment thereof. XBP-1 deficiency causes leukemic cells to acquire phenotypes that are disadvantageous for their survival, such as compromised BCR signaling capability and increased surface expression of S1 P1. | 03-24-2016 |
Manel Del Valle, Terrassa ES
Patent application number | Description | Published |
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20150293048 | CHEMOMETRIC ANALYSIS OF CHEMICAL AGENTS USING ELECTROCHEMICAL DETECTION AND CLASSIFICATION TECHNIQUES - Methods, systems, and devices are disclosed for the identification of chemical agents and determination of their level of exposure using electrochemical detection and advanced signal processing. In one aspect, a method includes collecting a sample from a surface containing a chemical agent to an electrode on a sensor such that the chemical agent transfers on the electrode, detecting an electrochemical signal of the chemical agent on the electrode to transduce chemical information associated with the chemical agent to an electrical signal, processing the electrical signal to obtain electrochemical spectral signature data to identify the chemical agent and generating a series of coefficients of the electrochemical spectral signature data to reduce the data, and classifying the chemical information based on the series of coefficients among preselected data sets to determine a level of exposure to the chemical agent. | 10-15-2015 |