Sproat
Brian Sproat, Booischot BE
Patent application number | Description | Published |
---|---|---|
20140024819 | PURIFICATION OF TRIPHOSPHORYLATED OLIGONUCLEOTIDES USING CAPTURE TAGS - The present invention relates to a method of preparing triphosphate-modified oligonucleotides using a capture tag. The method allows the synthesis and purification of triphosphate-modified oligonucleotides in high yield and purity suitable for pharmaceutical applications. | 01-23-2014 |
Brian S. Sproat, Booischot BE
Patent application number | Description | Published |
---|---|---|
20140065172 | DELIVERY SYSTEM AND CONJUGATES FOR COMPOUND DELIVERY VIA NATURALLY OCCURRING INTRACELLULAR TRANSPORT ROUTES - The present invention relates to a delivery system that comprises a conjugate that facilitates the delivery of a compound such as a biologically-active macromolecule, a nucleic acid or a peptide in particular, into a cell. The present invention also relates to said conjugate for delivery of a compound, such as a biologically-active macromolecule, a nucleic acid or a peptide, into a cell. The present invention further relates to a pharmaceutical composition comprising said conjugate and to its use. The present invention also relates to a method of delivering a compound to a cell or an organism, preferably a patient. | 03-06-2014 |
Brian Stephen Sproat, Booischot BE
Patent application number | Description | Published |
---|---|---|
20140200338 | OLIGONUCLEOTIDES CONTAINING HIGH CONCENTRATIONS OF GUANINE MONOMERS - This invention pertains to methods for oligonucleotide synthesis, specifically the synthesis of oligonucleotides that contain a high content of guanine monomers. In more detail, the invention relates to a method for coupling a nucleoside phosphoramidite during the synthesis of an oligonucleotide to a universal support, to a first nucleoside, or to an extending oligonucleotide. The invention further relates to oligonucleotides obtainable by the methods of the invention. | 07-17-2014 |
Brian Stephen Sproat, Leuven BE
Patent application number | Description | Published |
---|---|---|
20090054362 | COMPOUNDS - The present invention provides novel aptamer derivatives which are useful in binding to and neutralising viruses. Pharmaceutical formulations comprising the aptamers and the use of the aptamers in screening for useful compounds are also provided. | 02-26-2009 |
Eliza Sproat, Columbus, OH US
Patent application number | Description | Published |
---|---|---|
20150053694 | Quick-cook bean pot - In summary there is provided in one embodiment a quick-cook bean pot which creates an environment whereby beans cook far more efficiently than traditional methods. | 02-26-2015 |
Richard Sproat, Portland, OR US
Patent application number | Description | Published |
---|---|---|
20140163952 | CONVERSION OF INPUT TEXT STRINGS - Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for transforming text strings. In general, one aspect of the subject matter described in this specification can be embodied in methods that include the actions of receiving input string having a plurality of terms, the input string being in a first form; transforming the input string from the first form to a second form including: applying one or more rules to the input string to identify one or more terms for translation, the one or more identified terms being fewer than the plurality of terms, translating the identified one or more terms to one or more translated terms in the second form, and transliterating the remaining terms of the plurality of terms into transliterated terms in the second form; and concatenating the translated and transliterated terms to form a hybrid output string in the second form. | 06-12-2014 |
Richard William Sproat, Mahomet, IL US
Patent application number | Description | Published |
---|---|---|
20140188474 | System and Method of Lattice-Based Search for Spoken Utterance Retrieval - A system and method are disclosed for retrieving audio segments from a spoken document. The spoken document preferably is one having moderate word error rates such as telephone calls or teleconferences. The method comprises converting speech associated with a spoken document into a lattice representation and indexing the lattice representation of speech. These steps are performed typically off-line. Upon receiving a query from a user, the method further comprises searching the indexed lattice representation of speech and returning retrieved audio segments from the spoken document that match the user query. | 07-03-2014 |
Richard William Sproat, Berkeley Heights, NJ US
Patent application number | Description | Published |
---|---|---|
20100169076 | Text-to-Scene Conversion - The invention relates to a method of converting a set of words into a three-dimensional scene description, which may then be rendered into three-dimensional images. The invention may generate arbitrary scenes in response to a substantially unlimited range of input words. Scenes may be generated by combining objects, poses, facial expressions, environments, etc., so that they represent the input set of words. Poses may have generic elements so that referenced objects may be replaced by those mentioned in the input set of words. Likewise, a character may be dressed according to its role in the set of words. Various constraints for object positioning may be declared. The environment, including but not limited to place, time of day, and time of year, may be inferred from the input set of words. | 07-01-2010 |
William Harvey Sproat, Cartersville, GA US
Patent application number | Description | Published |
---|---|---|
20090151596 | Fastload rail carrier for motor vehicles, freight and passengers - This invention is a rail grade load/unload rail carrier with primary vertical load bearing sub-assemblies positioned above the carrier body floor. Carrier body sub-assemblies are vertical columns with stay cables attached to rail carrier bar joist sides. The design features carrier body floor elevation slightly above rail grade, and detachable rail wheel bogies outside the carrier body, to enable motor vehicle rail grade loading/unloading. Rail wheel bogie variants may be used for rail gage adaptation. Further, loaded motor vehicles provide rail carrier motive power; drive wheels protruding downward through carrier floor apertures to bear on rail flanking traction strips. Traction strips connect to a vehicle staging platform which has; integral rails, rail line connection, and highway access. Autonomous motor vehicle carrier translation along rails and across the staging area, negates need for conventional rail terminal handling facilities. Alternatively, the staging platform provides a maneuvering surface for portable lifting equipment to handle non-motorized cargo, including intermodal freight containers and passenger enclosures. | 06-18-2009 |