Patent application number | Description | Published |
20110054583 | Flexible and Scalable Sensor Arrays for Recording and Modulating Physiologic Activity - An implantable sensor array incorporates active electronic elements to greatly increase the number of sensors and their density that can be simultaneously recorded and activated. The sensors can be of various configurations and types, for example: optical, chemical, temperature, pressure or other sensors including effectors for applying signals to surrounding tissues. The sensors/effectors are arranged on a flexible and stretchable substrate with incorporated active components that allow the effective size, configuration, number and pattern of sensors/effectors to be dynamically changed, as needed, through a wired or wireless means of communication. Active processing allows many channels to be combined either through analog or digital means such that the number of wires exiting the array can be substantially reduced compared to the number of sensors/effectors on the array. | 03-03-2011 |
20110230747 | IMPLANTABLE BIOMEDICAL DEVICES ON BIORESORBABLE SUBSTRATES - Provided herein are implantable biomedical devices and methods of administering implantable biomedical devices, making implantable biomedical devices, and using implantable biomedical devices to actuate a target tissue or sense a parameter associated with the target tissue in a biological environment. | 09-22-2011 |
20120143568 | SELF-ADAPTIVE BIO-SIGNAL AND MODULATION DEVICE - A sensor-effector system includes an array of sensor-effector transducers providing a plurality of sensed signals and applying a plurality of effector signals. The array provides signals to input signal conditioning circuitry which digitizes and filters the plurality of sensed signals. A processor receives the digitized signals, and processes them to generate multiple feature vectors. It also analyzes the feature vectors to identify patterns and classify the identified patterns and generates at least one response vector resulting from the recognized pattern. The response vector is applied to output signal conditioning circuitry, coupled which converts the response vector to at least one analog signal which is applied as an effector signal to the array of sensor-effector transducers. | 06-07-2012 |
20120157804 | High-Speed, High-Resolution Electrophysiology In-Vivo Using Conformal Electronics - Provided herein are biomedical devices and methods of making and using biomedical devices for sensing and actuation applications. For example, flexible and/or stretchable biomedical devices are provided including electronic devices useful for establishing in situ conformal contact with a tissue in a biological environment. The invention includes implantable electronic devices and devices administered to the surfaces(s) of a target tissue, for example, for obtaining electrophysiology data from a tissue such as cardiac, brain tissue or skin. | 06-21-2012 |
20120245481 | Method for automatic, unsupervised classification of high-frequency oscillations in physiological recordings - Oscillatory signals may be used to determine a region of a patient's body that is associated with a medical condition. As described herein, oscillatory signals may be detected using a high sensitivity, low specificity detector. The oscillatory signals may be representative of discrete events in a patient's body. The detected signals may be tested in the context of surrounding background activity to identify anomalous discrete physiologic events that are sufficiently different from the surrounding background activity. The anomalous discrete physiologic events having correlative morphological, time, or location characteristics may be automatically clustered and clusters of anomalous physiologic events may be determined that are indicative of at least one region of the patient's body that is associated with a medical condition. | 09-27-2012 |
20130072775 | Conformable Actively Multiplexed High-Density Surface Electrode Array for Brain Interfacing - Provided are methods and devices for interfacing with brain tissue, specifically for monitoring and/or actuation of spatio-temporal electrical waveforms. The device is conformable having a high electrode density and high spatial and temporal resolution. A conformable substrate supports a conformable electronic circuit and a barrier layer. Electrodes are positioned to provide electrical contact with a brain tissue. A controller monitors or actuates the electrodes, thereby interfacing with the brain tissue. In an aspect, methods are provided to monitor or actuate spatio-temporal electrical waveform over large brain surface areas by any of the devices disclosed herein. | 03-21-2013 |
20140163390 | Implantable Biomedical Devices on Bioresorbable Substrates - Provided herein are implantable biomedical devices and methods of administering implantable biomedical devices, making implantable biomedical devices, and using implantable biomedical devices to actuate a target tissue or sense a parameter associated with the target tissue in a biological environment. | 06-12-2014 |
20150080695 | Conformable Actively Multiplexed High-Density Surface Electrode Array for Brain Interfacing - Provided are methods and devices for interfacing with brain tissue, specifically for monitoring and/or actuation of spatio-temporal electrical waveforms. The device is conformable having a high electrode density and high spatial and temporal resolution. A conformable substrate supports a conformable electronic circuit and a barrier layer. Electrodes are positioned to provide electrical contact with a brain tissue. A controller monitors or actuates the electrodes, thereby interfacing with the brain tissue. In an aspect, methods are provided to monitor or actuate spatio-temporal electrical waveform over large brain surface areas by any of the devices disclosed herein. | 03-19-2015 |
Patent application number | Description | Published |
20120260133 | Visualizing Transaction Traces As Flows Through A Map Of Logical Subsystems - A method for diagnosing problems in a computer system by visualizing flows through subsystems of the computer system. Diagnostic tools include a user interface which includes a triage map which graphically depicts subsystems, such as applications, through which a Business Transaction flows, and the calling relationship between the subsystems. The subsystems can be depicted by nodes which include alerts and performance information. The user can run a command to find transactions of a specific Business Transaction and/or front end subsystem which meet filter criterion such as response time and user identifier. Each captured transaction can be listed with information such as response time and reporting agent. Details of a particular transaction instance, such as its invoked components, can also be viewed in a transaction trace. | 10-11-2012 |
20120260135 | Visualizing Relationships Between A Transaction Trace Graph And A Map Of Logical Subsystems - A method for diagnosing problems in a computer system by providing a user interface for visualizing flows through subsystems of the computer system, and allowing a user to explore relationships between a triage map which graphically depicts subsystems, and a transaction trace graph, which depicts a time sequence of invoked components of the subsystems. In one aspect, in response to a user selecting a portion of the transaction trace graph which depicts an invoked component, the user interface visually distinguishes one of the subsystems which invokes the invoked component. In another aspect, the transaction trace can be played back so that subsystems in the triage map are highlighted in turn, in a time sequence, as components of different subsystems are invoked. A time marker can skip to selected time points which result in updating of the triage map. | 10-11-2012 |
Patent application number | Description | Published |
20090043141 | Oxidative coupling of methane - A microchannel apparatus comprising a conduit including a microchannel mixing section, a microchannel reaction section, a microchannel heat transfer section, and a separation section, where the microchannel mixing section includes direct injection inlets, where the microchannel mixing section is downstream from the reaction section, and where the separation section is downstream from the reaction section. Further exemplary embodiments are also disclosed. | 02-12-2009 |
20100024645 | METHODS FOR APPLYING MICROCHANNELS TO SEPARATE GASES USING LIQUID ABSORBENTS, ESPECIALLY IONIC LIQUID (IL) ABSORBENTS - Methods of using microchannel separation systems including absorbents to improve thermal efficiency and reduce parasitic power loss. Energy is typically added to desorb a solute and then energy or heat is removed to absorb a solute using a working solution. The working solution or absorbent may comprise an ionic liquid, or other fluids that demonstrate a difference in affinity between a solute and other gases in a solution. | 02-04-2010 |
20100280136 | INTEGRATED MICROCHANNEL SYNTHESIS AND SEPARATION - A process for carrying out at least two unit operations in series, the process comprising the step of: (a) directing a feed stream into an integrated assembly which comprises a first microchannel unit operation upon at least one chemical of the feed stream to generate a distributed output stream that exits the first microchannel unit operation in a first set of discrete microchannels isolating flow through the discrete microchannels; and (b) directing the distributed output stream of the first microchannel unit operation into a second microchannel unit operation as a distributed input stream, to continue isolating flow between the first set of discrete microchannels, and conducting at least one operation upon at least one chemical of the input stream to generate a product stream that exits the second microchannel unit operation, where the first microchannel unit operation and the second unit operation share a housing. | 11-04-2010 |
20140186229 | INTEGRATED MICROCHANNEL SYNTHESIS AND SEPARATION - An integrated microchannel reactor and heat exchanger comprising: (a) a waveform sandwiched between opposing shim sheets and mounted to the shim sheets to form a series of microchannels, where each microchannel includes a pair of substantially straight side walls, and a top wall formed by at least one of the opposing shim sheets, and (b) a first set of microchannels in thermal communication with the waveform, where the waveform has an aspect ratio greater than two. | 07-03-2014 |
20150045459 | INTEGRATED MICROCHANNEL SYNTHESIS AND SEPARATION - An integrated microchannel reactor and heat exchanger comprising: (a) a waveform sandwiched between opposing shim sheets and mounted to the shim sheets to form a series of microchannels, where each microchannel includes a pair of substantially straight side walls, and a top wall formed by at least one of the opposing shim sheets, and (b) a first set of microchannels in thermal communication with the waveform, where the waveform has an aspect ratio greater than two. | 02-12-2015 |