Patent application number | Description | Published |
20080210125 | Stable cement composition for orthopaedic and dental use - The present invention relates to ceramic precursor compositions and chemically bonded ceramic (CBC) materials, especially Ca-based, and composite biomaterials suitable for orthopaedic and dental applications with improved setting and curing properties resulting in stable close contact between biomaterial and bone tissue. The present invention also relates to a method of manufacturing said cured material, a bioelement and carrier material for drug delivery made by said cured material, a kit comprising the ceramic precursor powder and hydration liquid, as well as the use of said ceramic precursor powder and hydration liquid, or said cured material, for orthopaedic and dental applications. | 09-04-2008 |
20080213337 | DRUG IMPLANT CARRIER FOR DRUG DELIVERY - The present invention relates to ceramic precursor material exhibiting injectability arid properties that make the material suitable as a carrier material used in drug delivery. According to the invention this is accomplished by selecting a microstructure based on pre-reacted phases and after injection established phases, which contain anti-infective and/or anti-inflammatory drugs. The present invention also relates to a cured ceramic material and a method of manufacturing said cured material. The precursor and the cured ceramic material according to the present invention can suitably be used for filling orthopaedic cavities and other bone voids. | 09-04-2008 |
20080214500 | Injectable cement composition for orthopaedic and dental use - The present invention relates to ceramic precursor powder compositions and chemically bonded ceramic (CBC) materials, Ca-aluminate and/or calcium silicate, and a composite biomaterial with prolonged shelf time of the precursor, suitable for orthopaedic applications with improved injectability. The present invention also relates to a method of manufacturing said cured material, bioelements, implants, or drug delivery carrier materials made by said cured material, a kit comprising the ceramic precursor powder and hydration liquid, as well as the use of said ceramic precursor powder and hydration liquid, or said cured material, for orthopaedic and dental applications. | 09-04-2008 |
20090050015 | Dental cement system, a powdered material and a hydration liquid therefor, and ceramic material formed therefrom - A dental cement system, including an aqueous hydration liquid and a powdered material that essentially consists of an inorganic cement system, which powdered material has the capacity to form a complex, chemically bonded material with inorganic as well as organic phases with properties suitable for cementation of implant to another implant and/or to tooth or bone tissue. | 02-26-2009 |
20090061003 | CARRIERS FOR DRUG DELIVERY - The present invention relates to chemically bonded ceramic precursor material of aluminates and silicates exhibiting a controlled release rate and properties that make the material suitable as a carrier material used in drug delivery. According to the invention, this is accomplished by selecting a microstructure based on pre-reacted phases and/or reacting phases, which contains the drugs. The present invention also relates to a cured ceramic material and a method of manufacturing said cured material. The precursor and the cured ceramic material according to the present invention can suitably be used for different types of drug intake and delivery. | 03-05-2009 |
20090192513 | RESORBABLE CERAMIC COMPOSITIONS - Ceramic precursor compositions and chemically bonded ceramic (CBC) materials, especially Ca-based, and a composite biomaterial suitable for orthopaedic applications. The CBC-system includes a binding phase (chemical cement) and additional phases with specified chemistry imparting to the biomaterial the ability of initial strength followed by interaction with the body tissue including body liquid, to form a resorbable or partly resorbable biomaterial. The ceramic precursor composition includes at least one silicate with Ca as the main cation with a resorption rate less or equal to that of the bone in-growth rate. The silicate will form the binding phase of the cured material. Implants and surface coated devices are also disclosed. The cured material exhibits a compressive strength exceeding 100 MPa. | 07-30-2009 |
20100050902 | INJECTABLE CEMENT COMPOSITION FOR ORTHOPAEDIC AND DENTAL USE - The present invention relates to ceramic precursor powder compositions and chemically bonded ceramic (CBC) materials, Ca-aluminate and/or calcium silicate, and a composite biomaterial with prolonged shelf time of the precursor, suitable for orthopaedic applications with improved injectability. The present invention also relates to a method of manufacturing said cured material, bioelements, implants, or drug delivery carrier materials made by said cured material, a kit comprising the ceramic precursor powder and hydration liquid, as well as the use of said ceramic precursor powder and hydration liquid, or said cured material, for orthopaedic and dental applications. | 03-04-2010 |
Patent application number | Description | Published |
20100331978 | Antipathogenic Biomedical Implants, Methods and Kits Employing Photocatalytically Active Material - An antipathogenic biomedical implant is formed throughout its structure of a matrix material comprising at least about 1 weight percent of a photocatalytically active filler which exhibits an antipathogenic effect upon irradiation with light. The photocatalytically active filler is arranged in the matrix material in the implant to receive light irradiated from an external light source. In another embodiment, an antipathogenic biomedical implant comprises at least about 1 weight percent of a photocatalytically active material which exhibits an antipathogenic effect upon irradiation with light, wherein the photocatalytically active material is arranged in the implant to receive light irradiated from an external light source. Methods for providing an antipathogenic biomedical implant, methods for reducing pathogens on a biomedical implant, methods for reducing the bioburden in a biomedical implant installation, and kits for providing an antipathogenic biomedical implant employ the antipathogenic biomedical implants. | 12-30-2010 |
20120087954 | ION SUBSTITUTED CALCIUM PHOSPHATE COATINGS - A method for the formation of a surface coating of an ion substituted calcium phosphate on a substrate, the coating itself and the use of the coating. | 04-12-2012 |
20120134919 | Ion substituted calcium phosphate particles - A method for formation of spherical particles of ion substituted calcium phosphate. The method is based on precipitation of particles from a buffered solution under static, stirring or hydrothermal conditions. Also, the use of the formed materials and the particles in itself. | 05-31-2012 |
20120252845 | COMPOSITION FOR SUSTAINED DRUG DELIVERY COMPRISING GEOPOLYMERIC BINDER - The present invention relates to a sustained release medical composition comprising an active pharmaceutical ingredient and a geopolymeric binder. Preferably the active pharmaceutical ingredient is combined with the geopolymeric binder during the formation of that binder. | 10-04-2012 |
20120330435 | Implants and Methods for Correcting Tissue Defects - The present invention relates to mosaic implant ( | 12-27-2012 |
20130030361 | COATED MEDICAL IMPLANT - The present invention relates to a coated medical implant wherein the coating comprises an amorphous Me oxide layer or an (Al, Me) oxide layer deposited by physical vapor deposition, and wherein Me can be one or more of the elements of Ti, Si, Cr, Hf, Zr, Ta or Nb. The PVD layer does not have any bioactive/osseointegrating properties at temperatures below 45° C. This makes it easy to remove the implant after it has being inserted in an animal or human body, e.g. when used for fixating fractures. The coating may further comprise a calcium phosphate layer, preferably a hydroxyapatite layer, which is grown on the PVD layer using a biomimetic process. The coating may be loaded with a releasable agent such as a pharmaceutical agent, an ion or a bio molecule. The present invention also relates to a method for forming the coated medical implant. | 01-31-2013 |
20130066324 | HYDRAULIC CEMENTS, METHODS AND PRODUCTS - A hydraulic cement composition comprises a mixture of (a) a cement powder composition which is soluble or partly soluble in water, (b) a non-aqueous water-miscible liquid, and (c) an aqueous hydration liquid. Methods of producing a hardened cement, hardened cements, kits, and articles of manufacture employ such compositions. | 03-14-2013 |
20130066325 | HYDRAULIC CEMENTS WITH OPTIMIZED GRAIN SIZE DISTRIBUTION, METHODS, ARTICLES AND KITS - A non-aqueous hydraulic cement composition comprises a non-aqueous mixture of (a) β-tricalcium phosphate powder, (b) monocalcium phosphate powder, and (c) non-aqueous water-miscible liquid, wherein (i) at least about 90% of the monocalcium phosphate powder has a grain size in a range of about 200-600 μm and the powder (weight) to liquid (volume) ratio is about 2.5-5.5, (ii) at least about 90% of the monocalcium phosphate powder has a grain size in a range of about 1-400 μm and the powder (weight) to liquid (volume) ratio is about 2-5, or (iii) at least about 90% of the monocalcium phosphate powder has a grain size in a range of about 1-600 μm and the powder (weight) to liquid (volume) ratio is about 2.5-5.5. Methods, hardened cements, articles of manufacture and kits employ such compositions. | 03-14-2013 |
20130066327 | HYDRAULIC CEMENT COMPOSITIONS WITH LOW PH METHODS, ARTICLES AND KITS - A non-aqueous hydraulic cement composition comprises a non-aqueous mixture of (a) β-tricalcium phosphate powder, (b) monocalcium phosphate comprising monocalcium phosphate anhydrous (MCPA), monocalcium phosphate monohydrate (MCPM), or a combination thereof, and (c) non-aqueous water-miscible liquid, wherein a 0.1 g/ml saturated aqueous solution of the monocalcium phosphate has a pH less than 3.0. Methods of producing a hardened cement, hardened cements, kits, and articles of manufacture employ such compositions. | 03-14-2013 |
20130273119 | TRANSDERMAL DRUG ADMINISTRATION DEVICE - A transdermal drug administration device comprising a drug delivery element ( | 10-17-2013 |
20140195004 | Implants and Methods for Correcting Tissue Defects - The present invention relates to mosaic implant ( | 07-10-2014 |
20140221303 | Hydraulic Cements, Methods and Products - Non-aqueous hydraulic cement compositions comprise a non-aqueous mixture of a powder composition and a non-aqueous water-miscible liquid. In one embodiment, powder composition is a Brushite or Monetite-forming calcium phosphate powder composition. In another embodiment, the powder composition comprises porous β-tricalcium phosphate (β-TCP) granules and at least one additional calcium phosphate powder. In another embodiment, the powder composition comprises calcium silicate powder. In a further embodiment, the powder composition comprises calcium aluminate powder. In another embodiment, the powder composition is a cement composition and comprises nanopowders having a grain size of less than 1 micron. Hardened cements are formed from such hydraulic cement compositions, and methods of producing hardened cements, kits, and articles of manufacture employ such hydraulic cement compositions. | 08-07-2014 |
20140277571 | IMPLANTS WITH WEAR RESISTANT COATINGS AND METHODS - An implant comprises a substrate and a coating on a surface of the substrate, and the coating comprises silicon nitride and has a thickness of from about 1 to about 15 micrometer. A method of providing the implant comprises coating a surface of the implant substrate with the coating comprising silicon nitride and having a thickness of from about 1 to about 15 micrometer by physical vapour deposition. | 09-18-2014 |
20140312517 | Storage Stable Premixed Hydraulic Cement Compositions, Cements, Methods, and Articles - Refrigerated hydraulic cement compositions comprise a mixture of (a) β-tricalcium phosphate powder, (b) monocalcium phosphate comprising monocalcium phosphate anhydrous (MCPA), monocalcium phosphate monohydrate (MCPM), or a combination thereof, wherein a 0.1 g/ml saturated aqueous solution of the monocalcium phosphate has a pH less than 3.0, (c) non-aqueous water-miscible liquid, and (d) an aqueous hydrating liquid. The aqueous hydrating liquid is included in an amount of about 1-50 volume percent, based on the combined volume of the non-aqueous water-miscible liquid and the aqueous hydration liquid, and the refrigerated hydraulic cement composition is storage stable for greater than one day, without setting. Methods of forming hardened cements in vivo and/or for forming implants for use in vivo employ the hydraulic cement compositions. | 10-23-2014 |
20140324187 | Implants and Methods for Correcting Tissue Defects - An implant comprises a plurality of discrete biocompatible molded cement mosaic plates of maximum width w and thickness d connected by wire arms molded into and extending substantially laterally from the mosaic plates. Neighbouring mosaic plates are separated by a gap of width t, and at least some of the mosaic plates have a hexagon shape. | 10-30-2014 |
Patent application number | Description | Published |
20100331978 | Antipathogenic Biomedical Implants, Methods and Kits Employing Photocatalytically Active Material - An antipathogenic biomedical implant is formed throughout its structure of a matrix material comprising at least about 1 weight percent of a photocatalytically active filler which exhibits an antipathogenic effect upon irradiation with light. The photocatalytically active filler is arranged in the matrix material in the implant to receive light irradiated from an external light source. In another embodiment, an antipathogenic biomedical implant comprises at least about 1 weight percent of a photocatalytically active material which exhibits an antipathogenic effect upon irradiation with light, wherein the photocatalytically active material is arranged in the implant to receive light irradiated from an external light source. Methods for providing an antipathogenic biomedical implant, methods for reducing pathogens on a biomedical implant, methods for reducing the bioburden in a biomedical implant installation, and kits for providing an antipathogenic biomedical implant employ the antipathogenic biomedical implants. | 12-30-2010 |
20110184529 | Implants Comprising Titanium and Carbonate and Methods of Producing Implants - The invention relates to a substrate comprising a bioactive element and a method to obtain the substrate with the bioactive element. The plate comprising the bioactive element relies upon formation of a carbonate layer containing biologically relevant and active ions on a surface of the substrate. Via the surface modification and mineralization, features such as bone bioactivity and/or sustained ion release can be achieved. This is beneficial for the fixation and thus the long-term outcome of implanted materials. | 07-28-2011 |
20110313052 | Composition Comprising Biodegradable Carrier for Controlled Delivery - The present invention relates to a controlled release medical composition comprising: a powder composition of a binder; a water based liquid; and a medical active pharmaceutical ingredient. In a first embodiment the powder composition comprises at least calcium carbonate of a first phase and calcium carbonate of a second different phase, the first and second phase are selected from the group: amorphous calcium carbonate; vaterite; aragonite; and calcite; and in a second embodiment the powder composition comprises calcium carbonate, or calcium sulphate, or calcium phosphate, or combinations thereof. | 12-22-2011 |
20120022023 | Hydraulic Cements, Methods and Products - Non-aqueous hydraulic cement compositions comprise a non-aqueous mixture of a powder composition and a non-aqueous water-miscible liquid. In one embodiment, powder composition is a Brushite or Monetite-forming calcium phosphate powder composition. In another embodiment, the powder composition comprises porous β-tricalcium phosphate (β-TCP) granules and at least one additional calcium phosphate powder. In another embodiment, the powder composition comprises calcium silicate powder. In a further embodiment, the powder composition comprises calcium aluminate powder. In another embodiment, the powder composition is a cement composition and comprises nanopowders having a grain size of less than | 01-26-2012 |
20120330435 | Implants and Methods for Correcting Tissue Defects - The present invention relates to mosaic implant ( | 12-27-2012 |
20130066324 | HYDRAULIC CEMENTS, METHODS AND PRODUCTS - A hydraulic cement composition comprises a mixture of (a) a cement powder composition which is soluble or partly soluble in water, (b) a non-aqueous water-miscible liquid, and (c) an aqueous hydration liquid. Methods of producing a hardened cement, hardened cements, kits, and articles of manufacture employ such compositions. | 03-14-2013 |
20130066325 | HYDRAULIC CEMENTS WITH OPTIMIZED GRAIN SIZE DISTRIBUTION, METHODS, ARTICLES AND KITS - A non-aqueous hydraulic cement composition comprises a non-aqueous mixture of (a) β-tricalcium phosphate powder, (b) monocalcium phosphate powder, and (c) non-aqueous water-miscible liquid, wherein (i) at least about 90% of the monocalcium phosphate powder has a grain size in a range of about 200-600 μm and the powder (weight) to liquid (volume) ratio is about 2.5-5.5, (ii) at least about 90% of the monocalcium phosphate powder has a grain size in a range of about 1-400 μm and the powder (weight) to liquid (volume) ratio is about 2-5, or (iii) at least about 90% of the monocalcium phosphate powder has a grain size in a range of about 1-600 μm and the powder (weight) to liquid (volume) ratio is about 2.5-5.5. Methods, hardened cements, articles of manufacture and kits employ such compositions. | 03-14-2013 |
20130066327 | HYDRAULIC CEMENT COMPOSITIONS WITH LOW PH METHODS, ARTICLES AND KITS - A non-aqueous hydraulic cement composition comprises a non-aqueous mixture of (a) β-tricalcium phosphate powder, (b) monocalcium phosphate comprising monocalcium phosphate anhydrous (MCPA), monocalcium phosphate monohydrate (MCPM), or a combination thereof, and (c) non-aqueous water-miscible liquid, wherein a 0.1 g/ml saturated aqueous solution of the monocalcium phosphate has a pH less than 3.0. Methods of producing a hardened cement, hardened cements, kits, and articles of manufacture employ such compositions. | 03-14-2013 |
20130273119 | TRANSDERMAL DRUG ADMINISTRATION DEVICE - A transdermal drug administration device comprising a drug delivery element ( | 10-17-2013 |