Patent application number | Description | Published |
20100048547 | PI 3-KINASE INHIBITORS AND METHODS OF THEIR USE - Phosphatidylinositol (PI) 3-kinase inhibitor compounds, their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases, including proliferative diseases, inflammatory and obstructive airways diseases, allergic conditions, autoimmune and cardiovascular diseases. | 02-25-2010 |
20100249126 | PYRIMIDINE DERIVATIVES USED AS PI-3-KINASE INHIBITORS - Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases. | 09-30-2010 |
Patent application number | Description | Published |
20100160960 | HYDROGEL TISSUE ADHESIVE HAVING INCREASED DEGRADATION TIME - A hydrogel tissue adhesive having increased degradation time is described. The hydrogel tissue adhesive is formed by reacting an oxidized polysaccharide with a water-dispersible, multi-arm amine in the presence of a polyol additive, which retards the degradation of the hydrogel. The hydrogel may be useful as a tissue adhesive or sealant for medical applications, including but not limited to, ophthalmic applications such as sealing wounds resulting from trauma such as corneal lacerations, or from surgical procedures such as vitrectomy procedures, cataract surgery, LASIK surgery, glaucoma surgery, and corneal transplants; neurosurgery applications, such as sealing the dura; as a plug to seal a fistula or the punctum; adhesion prevention to prevent undesired tissue to tissue adhesions resulting from trauma or surgery; and as a hemostat sealant. | 06-24-2010 |
20120035129 | HYDROGEL TISSUE ADHESIVE HAVING REDUCED DEGRADATION TIME - A hydrogel tissue adhesive having decreased degradation time is described. The hydrogel tissue adhesive is formed by reacting an oxidized polysaccharide with a water-dispersible, multi-arm polyether amine in the presence of an oligomer additive, which promotes the degradation of the hydrogel. The hydrogel may be useful as a tissue adhesive or sealant for medical applications, such as a hemostat sealant or to prevent undesired tissue-to-tissue adhesions resulting from trauma or surgery. | 02-09-2012 |
20120094955 | METHOD OF DISSOLVING AN OXIDIZED POLYSACCHARIDE IN AN AQUEOUS SOLUTION - A method of dissolving an oxidized polysaccharide in an aqueous solution using an oligomer additive is described. The resulting aqueous solution of the oxidized polysaccharide may be used in combination with an aqueous solution comprising an amine-containing component to prepare hydrogel tissue adhesives and sealants for medical and veterinary applications, such as wound closure, supplementing or replacing sutures or staples in internal surgical procedures such as intestinal anastomosis and vascular anastomosis, tissue repair, ophthalmic procedures, drug delivery, and to prevent post-surgical adhesions. | 04-19-2012 |
20120285930 | PRINTING FORM AND PROCESS FOR PREPARING THE PRINTING FORM WITH CURABLE COMPOSITION HAVING EPOXY NOVOLAC RESIN - The invention pertains to a printing form and a process for preparing the printing form from a curable composition that includes an epoxy novolac resin having an epoxide equivalent weight of 156 to 300 g/equivalent, and an amine curing agent selected from primary amines and secondary amines, the agent having an amine equivalent weight of less than or equal to 60 g/equivalent. The process includes applying the curable composition to a supporting substrate to form a layer, curing the layer at one or more temperatures in a temperature range, and engraving to form at least one cell in the cured layer. The process prepares printing forms, particularly gravure printing forms, having a cured resin composition layer that is engravable, resistant to solvent inks and to mechanical wear, and capable of printing gravure-quality images. | 11-15-2012 |
20130165549 | PRINTING FORM AND PROCESS FOR PREPARING THE PRINTING FORM WITH CURABLE COMPOSITION HAVING SOLVENT-FREE EPOXY RESIN - The invention pertains to a printing form and a process for preparing the printing form from a solvent-free curable composition that includes, in prescribed relative amounts, an epoxy novolac resin; a bisphenol-A epoxy resin or a bisphenol-F epoxy resin; a monofunctional reactive diluent; a multifunctional reactive diluent; and a stoichiometric amount of an amine curing agent. The ratio of the epoxy novolac resin to the bisphenol epoxy resin is 1:3 to 3:1 by weight. The process includes applying the curable composition to a supporting substrate to form a layer, curing the layer at one or more temperatures in a temperature range, and engraving to form at least one cell in the cured layer. The process prepares printing forms, particularly gravure printing forms, having a cured resin composition layer that is engravable, resistant to solvent inks and to mechanical wear, and capable of printing gravure-quality images. | 06-27-2013 |
20140251168 | PRINTING FORM AND A PROCESS FOR PREPARING A PRINTING FORM USING TWO-STEP CURE - The invention pertains to a printing form and a process for preparing the printing form from a curable composition that includes an epoxy resin, less than a stoichiometric amount of at least one amine curing agent, and optionally a catalytic curing agent and/or a latent curing agent. The process includes applying the curable composition to a supporting substrate to form a layer, partially curing the layer at a first temperature, engraving the partially cured layer, and then completing the curing by heating at a second temperature greater than the first temperature. The less than stoichiometric amount of the amine curing agent guarantees that after the first curing step, epoxy functionalities in the curable composition will be available for second curing step. The optional catalytic curing agent or latent curing agent promotes completion of the cure at higher temperature. The process prepares printing forms, particularly gravure printing forms, having a cured resin composition layer that is engravable, resistant to solvent inks and to mechanical wear, and capable of printing gravure-quality images. | 09-11-2014 |
20150290961 | PRINTING FORM AND PROCESS FOR PREPARING THE PRINTING FORM WITH CURABLE COMPOSITION HAVING SOLVENT-FREE EPOXY RESIN - The invention pertains to a printing form and a process for preparing the printing form from a solvent-free curable composition that includes, in prescribed relative amounts, an epoxy novolac resin; a bisphenol-A epoxy resin or a bisphenol-F epoxy resin; a monofunctional reactive diluent; a multifunctional o reactive diluent; and a stoichiometric amount of an amine curing agent. The ratio of the epoxy novolac resin to the bisphenol epoxy resin is 1:3 to 3:1 by weight. The process includes applying the curable composition to a supporting substrate to form a layer, curing the layer at one or more temperatures in a temperature range, and engraving to form at least one cell in the cured layer. The process prepares printing forms, particularly gravure printing forms, having a cured resin composition layer that is engravable, resistant to solvent inks and to mechanical wear, and capable of printing gravure-quality images. | 10-15-2015 |
Patent application number | Description | Published |
20090034918 | Fiber optic cables having coupling and methods therefor - A fiber optic cable including at least one optical fiber disposed within a cavity of a cable jacket and methods for manufacturing the same are disclosed. The cavity has a first cavity cross-sectional area and a second cavity cross-sectional area located at different longitudinal locations along the cable, where the first cavity cross-sectional area is greater than the second cavity cross-sectional area. The region of the second cavity cross-sectional area of the cable provides and/or increases the coupling level of the at least one optical fiber to the cable jacket. In further embodiments, the fiber optic cable is a dry cable having one or more dry insert within the cavity for cushioning and/or optionally providing water-blocking for the cable. | 02-05-2009 |
20090034919 | Fiber optic cables using dry inserts for coupling and methods therefor - A fiber optic cable including at least one optical fiber and at least one dry insert disposed within a cavity of a cable jacket and methods for manufacturing the same are disclosed. The dry insert has a first thickness and a second thickness located at different longitudinal locations along the dry insert, where the first thickness is greater than the second thickness. The region of the cable having the first thickness of the dry insert provides and/or increases the coupling level of the at least one optical fiber to the cable jacket. In further embodiments, the optical fiber(s) have a predetermined level of coupling to the cable jacket that is about 0.1625 Newtons or more per optical fiber for a thirty meter length of fiber optic cable. | 02-05-2009 |
20090041411 | Fiber Optic Drop Cables and Preconnectorized Assemblies - A preconnectorized outdoor cable streamlines the deployment of optical waveguides into the last mile of an optical network. The preconnectorized outdoor cable includes a cable and at least one plug connector. The plug connector is attached to a first end of the cable, thereby connectorizing at least one optical waveguide. The cable has at least one optical waveguide, at least one tensile element, and a cable jacket. Various cable designs such as figure-eight or flat cables may be used with the plug connector. In preferred embodiments, the plug connector includes a crimp assembly having a crimp housing and a crimp band. The crimp housing has two half-shells being held together by the crimp band for securing the at least one tensile element. When fully assembled, the crimp housing fits into a shroud of the preconnectorized cable. The shroud aides in mating the preconnectorized cable with a complimentary receptacle. | 02-12-2009 |
20090060423 | Fiber Optic Drop Cables and Preconnectorized Assemblies Having Toning Portions - A preconnectorized outdoor cable streamlines the deployment of optical waveguides into the last mile of an optical network. The preconnectorized outdoor cable includes a cable and at least one plug connector. The plug connector is attached to a first end of the cable, thereby connectorizing at least one optical waveguide. The cable has at least one optical waveguide, at least one tensile element, and a cable jacket. Various cable designs such as figure-eight or flat cables may be used with the plug connector. In preferred embodiments, the plug connector includes a crimp assembly having a crimp housing and a crimp band. The crimp housing has two half-shells being held together by the crimp band for securing the at least one tensile element. When fully assembled, the crimp housing fits into a shroud of the preconnectorized cable. The shroud aides in mating the preconnectorized cable with a complimentary receptacle. | 03-05-2009 |
20090274425 | Fiber Optic Cables Having Coupling and Methods Therefor - A fiber optic cable including at least one optical fiber disposed within a cavity of a cable jacket and methods for manufacturing the same are disclosed. The cavity has a first cavity cross-sectional area and a second cavity cross-sectional area located at different longitudinal locations along the cable, where the first cavity cross-sectional area is greater than the second cavity cross-sectional area. The region of the second cavity cross-sectional area of the cable provides and/or increases the coupling level of the at least one optical fiber to the cable jacket. In further embodiments, the fiber optic cable is a dry cable having one or more dry insert within the cavity for cushioning and/or optionally providing water-blocking for the cable. | 11-05-2009 |
20100322563 | FIBER OPTIC DROP CABLES AND PRECONNECTORIZED ASSEMBLIES HAVING TONING PORTIONS - A preconnectorized outdoor cable streamlines the deployment of optical waveguides into the last mile of an optical network. The preconnectorized outdoor cable includes a cable and at least one plug connector. The plug connector is attached to a first end of the cable, thereby connectorizing at least one optical waveguide. The cable has at least one optical waveguide, at least one tensile element, and a cable jacket. Various cable designs such as figure-eight or flat cables may be used with the plug connector. In preferred embodiments, the plug connector includes a crimp assembly having a crimp housing and a crimp band. The crimp housing has two half-shells being held together by the crimp band for securing the at least one tensile element. When fully assembled, the crimp housing fits into a shroud of the preconnectorized cable. The shroud aides in mating the preconnectorized cable with a complimentary receptacle. | 12-23-2010 |
20110286706 | CABLE JACKET WITH VARIABLE PERIMETER BOND - The bond between an armor and a cable covering jacket is controlled by introducing intervening material at the interface of the layers along selected bond regions. The intervening material can comprise particulate matter or a strip of material introduced at selected locations of the armor perimeter to allow ease of access at the selected regions. | 11-24-2011 |