Patent application number | Description | Published |
20090018553 | MULTI-ACTUATING TRIGGER ANCHOR DELIVERY SYSTEM - A single trigger system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchor devices for such purposes. | 01-15-2009 |
20100030262 | ANCHOR DELIVERY SYSTEM WITH REPLACEABLE CARTRIDGE - A system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchor devices for such purposes. | 02-04-2010 |
20100132523 | Replaceable brake mechanism for power equipment - Woodworking machines are disclosed having cutting tools adapted to cut workpieces. The machines include a safety system adapted to detect one or more dangerous conditions between a person and the cutting tool, and to stop movement of the cutting tool upon detection of the dangerous condition. At least part of the safety system is housed in a removable cartridge substantially sealed against entry of sawdust. | 06-03-2010 |
20100192741 | Table saw with improved safety system - A table saw having an adjustable blade, a detection system to detect contact between a person and the blade, and a brake mechanism to engage and stop the blade upon detection of contact between the person and the blade is disclosed. The saw includes a brake positioning system that adjusts the position of the brake mechanism to maintain the brake mechanism in an operative position relative to the blade as the position of the blade is adjusted. The saw also may include a retraction system that urges the blade downward, away from a user, upon detection of contact between a person and the blade. The retraction system may include a releasable gear. The saw may be constructed so that the blade is adjustable up and down around a pivot point downstream of the blade relative to the feed direction. | 08-05-2010 |
20110054493 | Multi-Actuating Trigger Anchor Delivery System - A single trigger system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchor devices for such purposes. | 03-03-2011 |
20110061768 | Brake mechanism for power equipment - Woodworking machines are disclosed having cutting tools adapted to cut workpieces. The machines include a detection system adapted to detect one or more dangerous conditions between a person and the cutting tool. The machines also include a brake mechanism having one or more braking components adapted to engage and stop the cutting tool in response to the detection of a dangerous condition. | 03-17-2011 |
20120245600 | ANCHOR DELIVERY SYSTEM WITH REPLACEABLE CARTRIDGE - A system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchor devices for such purposes. | 09-27-2012 |
20130096582 | ANCHOR DELIVERY SYSTEM - A system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchor devices for such purposes. | 04-18-2013 |
20130296889 | ANCHOR DELIVERY SYSTEM - A system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchor devices for such purposes. | 11-07-2013 |
20130296935 | MULTI-ACTUATING TRIGGER ANCHOR DELIVERY SYSTEM - A single trigger system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchor devices for such purposes. | 11-07-2013 |
20140275756 | Devices, Systems and Methods for Treating Benign Prostatic Hyperplasia and Other Conditions - Devices, systems and methods for compressing, cutting, incising, reconfiguring, remodeling, attaching, repositioning, supporting, dislocating or altering the composition of tissues or anatomical structures to alter their positional or force relationship to other tissues or anatomical structures. In some applications, the invention may be used to improve patency or fluid flow through a body lumen or cavity (e.g., to limit constriction of the urethra by an enlarged prostate gland). | 09-18-2014 |
Patent application number | Description | Published |
20090105057 | Board sport training device and method of use - A board sport training device comprises a base configured for attachment to a platform such that the base is disposed beneath the platform. The base comprises a plurality of separate base portions, each base portion comprising at least two bowl-shaped pivot areas and each base portion having sufficient flexibility that each base portion conforms to a curved bottom surface of the platform. A plurality of the pivot areas are positioned along a longitudinal axis of the platform and separated by a distance from the platform. | 04-23-2009 |
20120226122 | Inserter for in-vitro analyte sensor - A device and method for implanting an analyte sensor into a subcutaneous fat layer is presented. The device comprises a housing that is positioned above the subcutaneous fat layer, a blade shuttle, and a sensor shuttle. In one embodiment, a spring is compressed between the blade shuttle and the sensor shuttle. The blade shuttle and sensor shuttle move towards the subcutaneous fat layer. When a spring force is released by the spring, the blade shuttle moves towards and pierces into the subcutaneous fat layer creating a pathway into the subcutaneous fat layer. The analyte sensor is implanted by the sensor shuttle by following the blade shuttle into the pathway created by the blade shuttle. The blade shuttle is then retracted from the subcutaneous fat layer, leaving the analyte sensor in the fat layer. | 09-06-2012 |
20120329365 | NON-ROLLABLE TO ROLLABLE TRANSFORMING TOY - A transformable toy with an alterable exterior structure. The toy is constructed to transform from a non-rollable first shape to a second rollable shape. An interior structure inside the exterior structure includes two or more exterior wall portions that collectively define a sphere, the wall portions moveably coupled relative to each and actuated by a triggering mechanism reactive to a magnetic force that is initiated external to the toy, and a biasing member that effects a force which transitions the wall portions to control the exterior structure—from a non-rollable (e.g., half-sphere or the like) first shape to a rollable (e.g., sphere or the like) second shape. Without initiation of the magnetic force, the first shape is maintained. With initiation of the magnetic force, the first shape transforms to the second shape. | 12-27-2012 |
Patent application number | Description | Published |
20090109250 | METHOD AND APPARATUS FOR SUPPORTING A SUBSTRATE - Methods and apparatus for supporting a substrate are provided. According to one aspect of the invention, a substrate support is provided which includes a first major surface comprising a plurality of flat support tiles and a plurality of leveling mechanisms coupled to the plurality of support tiles, wherein the plurality of leveling mechanisms are adapted to level the plurality of flat support tiles with respect to each other so as to provide a flat and level first major surface of the substrate support. Numerous other aspects are provided. | 04-30-2009 |
20090195262 | IN-LINE ELECTRON BEAM TEST SYSTEM - A method and apparatus for testing a plurality of electronic devices formed on a large area substrate is described. In one embodiment, the apparatus performs a test on the substrate in one linear axis in at least one chamber that is slightly wider than a dimension of the substrate to be tested. Clean room space and process time is minimized due to the smaller dimensions and volume of the system. | 08-06-2009 |
20090255911 | LASER SCRIBING PLATFORM AND HYBRID WRITING STRATEGY - Laser scribing can be performed on a workpiece ( | 10-15-2009 |
20100327162 | IN-LINE ELECTRON BEAM TEST SYSTEM - A method and apparatus for testing a plurality of electronic devices formed on a large area substrate is described. In one embodiment, the apparatus performs a test on the substrate in one linear axis in at least one chamber that is slightly wider than a dimension of the substrate to be tested. Clean room space and process time is minimized due to the smaller dimensions and volume of the system. | 12-30-2010 |
20130068161 | GAS DELIVERY AND DISTRIBUTION FOR UNIFORM PROCESS IN LINEAR-TYPE LARGE-AREA PLASMA REACTOR - An apparatus for introducing gas into a processing chamber comprising one or more gas distribution tubes having gas-injection holes which may be larger in size, greater in number, and/or spaced closer together at sections of the gas introduction tubes where greater gas conductance through the gas-injection holes is desired. An outside tube having larger gas-injection holes may surround each gas distribution tube. The gas distribution tubes may be fluidically connected to a vacuum foreline to facilitate removal of gas from the gas distribution tube at the end of a process cycle. | 03-21-2013 |
Patent application number | Description | Published |
20090170719 | SUPERIOR HYBRIDIZATION PROBES AND METHODS FOR THEIR USE IN DETECTION OF POLYNUCLEOTIDE TARGETS - We describe new hybridization probes and methods for their use in detection, identification, and quantitation of polynucleotides such as RNA and DNA. Ordinary short oligonucleotide probes usually provide higher sequence-specificity but lower efficacy of hybridization than longer ordinary polynucleotide probes where both are fully complementary to the target polynucleotide. Our new polynucleotide probes combine the hybridization efficacy of long probes with the sequence-specificity of short probes. The polynucleotide probes contain a target binding domain and a binding enhancer domain, where the binding enhancer domain does not for stable structures under hybridizing conditions with the target binding domain or its corresponding target. These binding enhancer domains are able to improve the hybridization features of the target binding domain as well as the signal-to-noise ratio for target detection. Detection methods based on these probes allow fast, accurate, and sensitive detection of target polynucleotides (either qualitatively or quantitatively) and can be easily multiplexed. | 07-02-2009 |
20090170794 | Small interfering rnas that efficiently inhibit viral expression and methods of use thereof - The invention provides methods, compositions, and kits comprising small interfering RNA (shRNA or siRNA) which are useful for inhibition of viralmediated gene expression. Small interfering RNAs as described herein may be used in methods of treatment of HCV infection. ShRNA and siRNA constructs that target the internal ribosome entry site (IRES) sequence of HCV are described. | 07-02-2009 |
20100112686 | SHORT HAIRPIN RNAS FOR INHIBITION OF GENE EXPRESSION - Methods, compositions, and kits that include small hairpin RNA (shRNA) useful for inhibition of gene expression, such as viral-mediated gene expression, are described. | 05-06-2010 |
20110269816 | Inhibition of Viral Gene Expression Using Small Interfering RNA - The invention provides methods, compositions, and kits comprising small interfering RNA (shRNA or siRNA) that are useful for inhibition of viral-mediated gene expression. Small interfering RNAs as described herein can be used in methods of treatment of HCV infection. ShRNA and siRNA constructs targetING the internal ribosome entry site (IRES) sequence of HCV are described. | 11-03-2011 |
20120164651 | METHODS AND COMPOSITIONS FOR DETECTION OF SMALL RNAS - Currently, the circularization of small RNAs is broadly regarded as an obstacle in ligation-related assays and explicitly avoided while short lengths of linear RNA targets is broadly recognized as a factor limiting use of conventional primers in PCR-related assays. In contrast, the disclosed invention capitalizes on circularization of small RNA targets or their conjugates with oligonucleotide adapters. The circular RNA templates provide amplification of the target sequences via synthesis of multimer nucleic acids that can be either labeled for direct detection or subjected to PCR amplification and detection. Structure of small circular RNAs and corresponding multimeric nucleic acids provide certain advantages over current methods including flexibility in design of conventional RT and PCR primers as well as use of 5′-overlapping dimer-primers for efficient and sequence-specific amplification of short target sequences. Our invention also reduces number of steps and reagents while increasing sensitivity and accuracy of detection of small RNAs with both 2′OH and 2′-OMe at their 3′ ends. Our invention increase sensitivity and specificity of detection of microRNAs and other small RNAs with both 2′OH and 2′-OMe at their 3′ ends while allowing us to distinguish these two forms from each other. | 06-28-2012 |
20120165397 | CHEMICAL MODIFICATION OF SHORT SMALL HAIRPIN RNAS FOR INHIBITION OF GENE EXPRESSION - Aspects of the present invention include the production and use of chemically modified RNAi agents (e.g., shRNAs) in gene silencing applications. The chemically modified RNAi agents disclosed herein have reduced immunostimulatory activity, increased serum stability, or both, as compared to a corresponding RNAi agent not having the chemical modification. Compositions containing chemically modified RNAi agents according to aspects of the present invention (including pharmaceutical compositions) and kits containing the same are also provided. | 06-28-2012 |
20120220033 | INHIBITION OF VIRAL GENE EXPRESSION USING SMALL INTERFERING RNA - The invention provides methods, compositions, and kits comprising small interfering RNA (shRNA or siRNA) that are useful for inhibition of viral-mediated gene expression. Small interfering RNAs as described herein can be used in methods of treatment of HCV infection. ShRNA and siRNA constructs targetING the internal ribosome entry site (IRES) sequence of HCV are described. | 08-30-2012 |
Patent application number | Description | Published |
20120144976 | BEATER BRACKET AND VARIABLE DRIVE LEVER SYSTEM WITH VARIABLE PIVOT POINT SPRING ROTOR FOR BASS DRUM FOOT PEDALS - Described is a bass drum foot pedal having a variable drive lever linkage with variable arc ratios connecting the foot pedal to a beater bracket. The beater bracket is formed with a mounting surface that tips a beater shaft forward to create a forward beater angle that maximizes the beater impact against a bass drum. | 06-14-2012 |
20120198984 | TOPSIDE SPRING TENSION ADJUSTER FOR BASS DRUM PEDALS WITH VARIABLE PIVOT POINT SPRING ROTOR - Described is a drum foot pedal with a tension adjuster for adjusting the tension of the spring and corresponding return action of a beater. The device includes a foot pedal and a beater bracket operably connected with the foot pedal such that the beater bracket is actuated in response to force applied to the foot pedal. A rocker component is attached with the beater bracket such that rotational motion of the beater bracket causes a rotational motion of the rocker component. A swivel component is connected with the rocker component. Further, a spring is attached with the swivel component for biasing the beater bracket to force a return action of a beater when force is removed from the foot pedal. Finally, a spring tension adjuster connected with and between the swivel component and spring, the spring tension adjuster operable for allowing a user to selectively adjust tension of the spring. | 08-09-2012 |
20130000460 | MOUNTING SYSTEM FOR ACOUSTIC MUSICAL INSTRUMENTS - Described is a mounting system for acoustic musical instruments. The mounting system includes a central hub with three suspension arms extending thereform. Each extension arm having a proximal end connected with the central hub and a distal end having a gripper arm assembly. A lower support cushion and a gripper pad are connected with each gripper arm assembly, both of which are formed of neoprene. Thus, a user can position a drum hoop on the lower support cushions and use the gripper pads to secure the drum therebetween. In doing so, the mounting system provides a secure, rigid grip on the instrument for performance, while ensuring the instrument is undamaged and fits all types of counter hoops in popular use. Additionally, due to the neoprene, the mounting system allows the acoustic instrument to resonate (speak) in a more unrestricted manner with respect to the prior art. | 01-03-2013 |
Patent application number | Description | Published |
20080293089 | Assays for Modulators of Parkin Activity Using Novel Substrates - The invention provides in vitro and cell-based assays for parkin activity, in which parkin-mediated ubiquitination of the S5a subunit of the 26S proteasome is measured, or ubiquitination of troponin 1. The assays may be used to screen for agents that modulate parkin protein ligase activity. | 11-27-2008 |
20090023178 | Parkin Substrate and Assay - The invention provides in vitro, ex vivo, and in vivo assays for Parkin activity, in which Parkin-mediated ubiquitination of a Sept4 protein is measured. The assays may be used to screen for agents that modulate Parkin protein ligase activity. | 01-22-2009 |
20090317825 | ASSAY FOR PARKINSON'S DISEASE THERAPEUTICS AND ENZYMATICALLY ACTIVE PARKIN PREPARATIONS USEFUL THEREIN - The invention provides to assays for agent useful for treatment of Parkinson's Disease. Included are cell-based assays for agents that modulate the effect of Parkin proteins on proteasome function. The invention also provides recombinant, enzymatically active, Parkin protein produced in prokaryotic expression systems, such as | 12-24-2009 |
20120083003 | PARKIN SUBSTRATE AND ASSAY - The invention provides in vitro, ex vivo, and in vivo assays for Parkin activity, in which Parkin-mediated ubiquitination of a Sept4 protein is measured. The assays may be used to screen for agents that modulate Parkin protein ligase activity. | 04-05-2012 |
20140186294 | PHAGOCYTIC ACTIVITY AS A MARKER OF SYNUCLEINOPATHIC DISEASE - The invention provides methods of screening for agents useful in treating or prophylaxis of synucleinopathic disease, methods of diagnosis or prognosis of the same and methods of treatment and prophylaxis. The invention is based in part on the result that cells with phagocytic activity from subjects with synucleinopathic disease have increased levels of alpha synuclein and reduced phagocytic activity and that these processes can be reversed (i.e., synuclein levels decreased and phagocytic levels increased) by treatment with IL-4 among other agents. The increase in phagocytic activity is readily amenable to detection and provides a basis for a screening assay in which an agent is contacted with phagocytic cells and the effect of the agent on phagocytic activity is detected, which is an indicator that the agent has the ability to reduce alpha synuclein levels. | 07-03-2014 |
Patent application number | Description | Published |
20110132431 | OPTOELECTRONIC DEVICE WITH BYPASS DIODE - Optoelectronic devices with bypass diodes are described. An optoelectronic device includes a bypass diode, a heat spreader unit disposed above, and extending over, the bypass diode, and a heat sink disposed above the heat spreader unit. Another optoelectronic device includes a bypass diode, a heat spreader unit disposed above, but not extending over, the bypass diode, and a heat sink disposed above the heat spreader unit. | 06-09-2011 |
20120031464 | DIODE AND HEAT SPREADER FOR SOLAR MODULE - Arrangements of diodes and heat spreaders for solar modules are described. For example, a solar module may include a backsheet with a low profile, surface-mount diode disposed above the backsheet. A pair of ribbon interconnects is coupled to the low profile, surface-mount diode and may penetrate the backsheet. | 02-09-2012 |
20120074576 | INTERCONNECT FOR AN OPTOELECTRONIC DEVICE - Interconnects for optoelectronic devices are described. An interconnect may include a stress relief feature. An interconnect may include an L-shaped feature. | 03-29-2012 |
20130163137 | CIRCUITS AND METHODS FOR LIMITING OPEN CIRCUIT VOLTAGE OF PHOTOVOLTAIC STRINGS - A photovoltaic string may include an open circuit voltage limiter that conducts current in one direction to provide a limiter voltage less than an open circuit voltage of the photovoltaic string, and that conducts current in the other direction. One or more open circuit voltage limiters may be connected across the photovoltaic string or across selected groups of solar cells of the photovoltaic string. The limiter voltage may be greater than a maximum power point voltage but less than the open circuit voltage of the photovoltaic string. | 06-27-2013 |
20130228906 | INTERCONNECT FOR AN OPTOELECTRONIC DEVICE - Interconnects for optoelectronic devices are described. For example, an interconnect for an optoelectronic device includes an interconnect body having an inner surface, an outer surface, a first end, and a second end. A plurality of bond pads is coupled to the inner surface of the interconnect body, between the first and second ends. A stress relief feature is disposed in the interconnect body. The stress relief feature includes a slot disposed entirely within the interconnect body without extending through to the inner surface, without extending through to the outer surface, without extending through to the first end, and without extending through to the second end of the interconnect body. | 09-05-2013 |
20130257155 | PHOTOVOLTAIC SYSTEMS WITH LOCAL MAXIMUM POWER POINT TRACKING PREVENTION AND METHODS FOR OPERATING SAME - A photovoltaic system includes solar cells and an inverter configured to convert direct current generated by the solar cells to alternating current. The photovoltaic system includes a maximum power point (MPP) tracking module configured to perform MPP tracking for the photovoltaic system. The MPP tracking module is configured to detect shading of the solar cells and to modify its MPP tracking to prevent tracking of local MPPs. The MPP tracking module may be incorporated in the inverter. | 10-03-2013 |
20140048119 | DIODE AND HEAT SPREADER FOR SOLAR MODULE - Arrangements of diodes and heat spreaders for solar modules are described. For example, a solar module may include a backsheet with a low profile, surface-mount diode disposed above the backsheet. A pair of ribbon interconnects is coupled to the low profile, surface-mount diode and may penetrate the backsheet. | 02-20-2014 |
20140153149 | CIRCUITS AND METHODS FOR LIMITING OPEN CIRCUIT VOLTAGE OF PHOTOVOLTAIC STRINGS - A photovoltaic string may include an open circuit voltage limiter that conducts current in one direction to provide a limiter voltage less than an open circuit voltage of the photovoltaic string, and that conducts current in the other direction. One or more open circuit voltage limiters may be connected across the photovoltaic string or across selected groups of solar cells of the photovoltaic string. The limiter voltage may be greater than a maximum power point voltage but less than the open circuit voltage of the photovoltaic string. | 06-05-2014 |
20140291852 | INTERCONNECT FOR AN OPTOELECTRONIC DEVICE - Interconnects for optoelectronic devices are described. For example, an interconnect for an optoelectronic device includes an interconnect body having an inner surface, an outer surface, a first end, and a second end. A plurality of bond pads is coupled to the inner surface of the interconnect body, between the first and second ends. A stress relief feature is disposed in the interconnect body. The stress relief feature includes a slot disposed entirely within the interconnect body without extending through to the inner surface, without extending through to the outer surface, without extending through to the first end, and without extending through to the second end of the interconnect body. | 10-02-2014 |
20140352761 | OPTOELECTRONIC DEVICE WITH BYPASS DIODE - Optoelectronic devices with bypass diodes are described. An optoelectronic device includes a bypass diode, a heat spreader unit disposed above, and extending over, the bypass diode, and a heat sink disposed above the heat spreader unit. Another optoelectronic device includes a bypass diode, a heat spreader unit disposed above, but not extending over, the bypass diode, and a heat sink disposed above the heat spreader unit. | 12-04-2014 |
Patent application number | Description | Published |
20110313736 | Method and Algorithm for Modeling and Simulating A Discrete-Event Dynamic System - A method for modeling, visualizing and simulating a large-scale discrete-event dynamic system, comprising the steps of expressing an algorithm that models a plurality of activity interactions, determining a plurality of possible relationships between a plurality of system elements including transient entities, resident entities, or both, providing a hierarchical mapping of the plurality of system elements and the plurality of possible relationships among the plurality of system elements, representing a relationship diagram as a graph notation where an activity or a system element is visualized as a node and the plurality of possible relationships among the activity or the system element as an arc, allowing an explicit description of the plurality of possible relationships among the activity or the system element and a plurality of possible ways in which the activity can begin and a sequence of activities, and representing an activity interaction matrix that categorizes the plurality of activity interactions. | 12-22-2011 |
20120005661 | Method for Just-in-Time Compilation and Execution of Code Blocks within Discrete Event Simulations - A method for a discrete event simulation model of a system utilizing a just-in-time compilation for one or more code blocks associated with an event in one or more discrete event simulation models is disclosed. The method comprises the steps of determining the event in a discrete event simulation model according to a kind of event, retrieving the code block associated with the event, compiling the code block into an object file using a compiler, linking the object file with a predetermined function in a simulation library, compiling the object file and the predetermined function into a customized dynamic link library, loading the customized dynamic link library (DLL) within a discrete event simulation program execution and linking the customized DLL to a simulation program. The method allows user entered logic to be executed in high speed by integrating a just-in-time compiler embedded into the simulation model to allow dynamic generation of high speed code blocks within one or more simulations. | 01-05-2012 |
20130275173 | Real-Time Publishing of Finite Schedules and Real-Time Response to Schedule Changes - A method for real-time publishing of a finite schedule that includes a plurality of activities and a plurality of resources is presented. The method utilizes at least one master schedule derived from an output of the finite schedule and at least one published schedule associated with the at least one master schedule. The at least one master schedule includes at least one master activity instance and the at least one published schedule includes at least one published activity instance. The method creates a schedule mapping table and an activity instance-mapping table. The schedule mapping table stores at least one relationship between the at least one master schedule and the at least one published schedule. Furthermore, the method updates the finite schedule and communicates schedule deviations in real-time with the finite schedule. | 10-17-2013 |
20140114637 | METHOD FOR JUST-IN-TIME COMPILATION AND EXECUTION OF CODE BLOCKS WITHIN DISCRETE EVENT SIMULATIONS - A method for a discrete event simulation model of a system utilizing a just-in-time compilation for one or more code blocks associated with an event in one or more discrete event simulation models is disclosed. The method comprises the steps of determining the event in a discrete event simulation model according to a kind of event, retrieving the code block associated with the event, compiling the code block into an object file using a compiler, linking the object file with a predetermined function in a simulation library, compiling the object file and the predetermined function into a customized dynamic link library, loading the customized dynamic link library (DLL) within a discrete event simulation program execution and linking the customized DLL to a simulation program. The method allows user entered logic to be executed in high speed by integrating a just-in-time compiler embedded into the simulation model to allow dynamic generation of high speed code blocks within one or more simulations. | 04-24-2014 |
Patent application number | Description | Published |
20090011417 | Testing Device - The invention provides, in different aspects, a system, sample preparation device, sample processing cartridge, kit, methods of use, business methods, and computer program product. | 01-08-2009 |
20090275014 | THERMAL CYCLING METHOD - This invention provides a method for carrying out nucleic acid amplification reactions involving heating and cooling of samples in sample vessels utilizing a heat block comprising a liquid. The method can be used to perform multiple nucleic acid amplification reactions simultaneously in which each of the reactions is performed so as to have temperature profiles. The apparatus can be used for performing PCR, and real time PCR in particular, with control and uniformity. | 11-05-2009 |
20090275113 | Thermal cycling apparatus - This invention provides an apparatus for providing heating and cooling of samples in sample vessels having uniform temperature profiles. The apparatus can be used for performing PCR, and real time PCR in particular, with control and uniformity. The system employs a heat block containing a liquid composition to efficiently transfer heat to and from reaction vessels. | 11-05-2009 |
20100279299 | Devices and Methods for Heating Biological Samples - This invention provides a systems and methods for regulating temperature and heat transfer in applications in which it is desirable to maintain temperature uniformity such as thermal cycling applications. A heat block is used to rapidly transfer heat to or from a set of one or more reaction vessels. | 11-04-2010 |
20120171678 | APPARATUS FOR THERMAL CYCLING - This invention provides a system for performing PCR, and real time PCR in particular, with great speed and specificity. The system employs a heat block containing a liquid composition to rapidly transfer heat to and from reaction vessels. The system makes use of the reflective properties of the liquid metal to reflect signal from the PCR into the vessel and out the top. In this way, the signal can be measured by an optical assembly in real time without removing the vessels from the heat block. | 07-05-2012 |
Patent application number | Description | Published |
20110172494 | SURGICAL RETRACTOR WITH CURVED ROTATING BLADES - Various embodiments of the present invention provide a surgical retractor having two blade-supporting arms, which are mounted to be laterally slideable towards and apart from each other by a toothed rack. Each arm supports a respective retractor blade. In some embodiments, the retractor blades are curved in the same direction as each other so that the first blade is concave in the first direction, and a second blade is also concave in the same direction. Alternatively or additionally, in some embodiments, a cushioned material or cushioned sleeve is present on the blades where the blades contact the anatomy. The cushioned material or sleeve may be made of a soft silicone. Further, the cushioned material or sleeve may be coated or molded onto the blade structure, or may be a removable sleeve that is manually slid onto or off of the blade structure. Also, alternatively or in addition in some embodiments, blade-mounted lighting may be provided. In some embodiments, the lighting may comprise a fiber optic light source that penetrates into and through the blade and terminates in an opening in the blade facing inward so that it shines light inwardly towards the direction of the other blade and/or towards the anatomy. One or both of the two opposed blades may have light sources shining generally inward. | 07-14-2011 |
20130204091 | ANTERIOR HIP REPLACEMENT RETRACTOR ASSEMBLY - A retractor assembly has a first clamp adapted to be mounted to a table, a first vertically oriented post supported by the clamp, a first main arm mounted for at least one of angular and lateral movement relative to the first post, and lockable in a selected position, and a tree assembly configured at one end of the second post. The tree assembly has at least two accessory arms, with each accessory arm having a first ball joint on a first end, and a pivot lock knob at an immediate portion, and each accessory arm having a second end configured to accept the mounting of a retractor to the accessory arm. The retractor assembly may also include a J-shaped hook mounted to a ratcheting linearly movable distractor assembly and trochanteric retractors mounted to the accessory arms for femoral elevation and exposure. | 08-08-2013 |
20130204262 | SURGICAL PROCESS FOR ANTERIOR HIP REPLACEMENT - Various exemplary embodiments relate to a method of performing an anterior approach hip replacement using a retractor assembly. The method may include: providing a retractor assembly including a first vertical post, a plurality of accessory arms mounted to the first post, a second vertical post, and a femur distractor mounted to the second post; exposing a surgical site including the femoral neck and acetabulum using a plurality of retractors secured to the accessory arms; cutting the femoral neck to remove the femoral head; preparing the acetabulum for insertion of an acetabular cup; preparing the femur for insertion of a femoral implant by lifting the femur using a femur hook and the femur distractor; and closing the surgical site. In various alternative embodiments, the retractors may include a lesser trochanteric retractor coming from a direct medial approach and a greater trochanteric retractor coming from a lateral, posterior, proximal approach. | 08-08-2013 |
20140003084 | FIBER OPTIC LIGHT SUPPLY SYSTEM AND CONNECTOR | 01-02-2014 |
20140358149 | SURGICAL PROCESS FOR ANTERIOR HIP REPLACEMENT - Various exemplary embodiments relate to a method of performing an anterior approach hip replacement. The method may include: exposing a surgical site including the femoral neck and acetabulum using a plurality of retractors secured to the plurality of accessory arms; cutting the femoral neck to remove the femoral head; preparing the acetabulum for insertion of an acetabular cup; preparing the femur for insertion of a femoral implant by lifting the femur using a femur hook and the femur distractor; and closing the surgical site. In various alternative embodiments, the method may include using a lesser trochanteric retractor corning from a direct medial approach and a greater trochanteric retractor coming from a lateral, posterior, proximal approach. | 12-04-2014 |
Patent application number | Description | Published |
20110160860 | CERVICAL SPACER - An anterior cervical column support having a hollow frame having a top load bearing surface and a bottom load bearing surface may be inserted between a first spinal vertebra and a second spinal vertebra. The top load bearing surface and the bottom load bearing surface may each include an opening allowing access to the interior of the frame. A front surface may extend between the top load bearing surface and the bottom load bearing surface, and a rear surface may extend between the top load bearing surface and the bottom load bearing surface. Two side surfaces are attached between the front surface and the rear surface, each side surface having a solid side panel that is at least x-ray translucent. An anterior (front) plate is attached to the front surface of the support device, where the front plate includes clearance holes for receiving fasteners for holding the front plate in position. The top load bearing surface and the bottom load bearing surface may include a serrated or other high friction surface for applying frictional forces between the load bearing surfaces and adjacent vertebrae. | 06-30-2011 |
20120316649 | CERVICAL SPACER - An anterior cervical column support having a hollow frame having a top load bearing surface and a bottom load bearing surface may be inserted between a first spinal vertebra and a second spinal vertebra. The top load bearing surface and the bottom load bearing surface may each include an opening allowing access to the interior of the frame. A front surface may extend between the top load bearing surface and the bottom load bearing surface, and a rear surface may extend between the top load bearing surface and the bottom load bearing surface. An anterior front plate is attached to the front surface of the support device. The interior front plate may be arranged along a plane (P), and an axis (A) between the top load bearing surface and the bottom load bearing surface may be at a non-zero angle relative to the plane (P) | 12-13-2012 |
20140107785 | BONE PLATE AND FUSION CAGE INTERFACE - Various exemplary embodiments relate to a spinal implant for insertion between two adjacent vertebrae, the spinal implant including one or more of the following: a cage comprising: a frame sized to be inserted between the vertebrae, the frame comprising a fastener hole and a cage alignment structure, the cage alignment structure comprising at least one of: a cage groove and a cage ridge; a bone plate comprising a bone plate alignment structure a through hole, wherein the bone plate alignment structure comprises at least one of a bone plate groove and a bone plate ridge, and wherein the bone plate alignment structure and the cage alignment structure are configured to interact with each other to provide an indication when the bone plate is properly aligned with the cage; and a fastener to attach the bone plate to the cage when inserted through the through hole and into the fastener hole. | 04-17-2014 |
20140107786 | FUSION CAGE IMPLANT WITH LATTICE STRUCTURE - Various exemplary embodiments relate to a spinal implant for insertion between two vertebrae including one or more of the following: a cage comprising: a frame including a fastener hole, a lattice structure disposed within the frame and exposed on a top and bottom face of the frame to permit bone growth into the lattice structure, and an inner rim disposed between the lattice structure and a through bore extending through the cage; a bone plate comprising a through hole, and a first and a second screw hole, wherein the first and second screw hole are positioned to overlie the vertebrae when the bone plate is attached to the cage and the cage is inserted between the two vertebrae; and a fastener operable to attach the bone plate to the cage when the fastener is inserted through the through hole of the bone plate and into the fastener hole of the frame. | 04-17-2014 |
Patent application number | Description | Published |
20090034713 | Projection Headset - A headset apparatus including a virtual keypad and a method for inputting data into a headset are provided. In one embodiment, a headset includes a processor, at least one acoustic transducer, a projector operably coupled to the processor for displaying an image on a surface exterior to the headset, and a position detector operably coupled to the processor for determining an image position and a user finger position. | 02-05-2009 |
20090279712 | Microphone Boom With Adjustable Wind Noise Suppression - A microphone boom cap includes a porous plastic portion adapted to cover a microphone boom first aperture. The microphone boom cap includes a non-porous plastic portion affixed to the porous plastic portion. The non-porous plastic portion is adapted to cover a microphone boom second aperture in a second use position, where the porous plastic portion covers the second aperture in a first use position. | 11-12-2009 |
20100020982 | DONNED/DOFFED MULTIMEDIA FILE PLAYBACK CONTROL - Methods and apparatuses for headset wearing mode based operation are presented. A headset system includes a first earbud and a second earbud. One or both earbuds have a detector which indicates whether the earbud is donned or doffed. Operation of the headset is modified based on the donned or doffed status of the earbuds. | 01-28-2010 |
20100020998 | HEADSET WEARING MODE BASED OPERATION - Methods and apparatuses for headset wearing mode based operation are presented. A headset system includes a first earbud and a second earbud. One or both earbuds have a detector which indicates whether the earbud is donned or doffed. Operation of the headset is modified based on the donned or doffed status of the earbuds. | 01-28-2010 |
20120020492 | Headset Wearing Mode Based Operation - Methods and apparatuses for headset wearing mode based operation are presented. A headset system includes a first earbud and a second earbud. One or both earbuds have a detector which indicates whether the earbud is donned or doffed. Operation of the headset is modified based on the donned or doffed status of the earbuds. | 01-26-2012 |
20120189136 | DONNED/DOFFED MULTIMEDIA FILE PLAYBACK CONTROL - Methods and apparatuses for headset wearing mode based operation are presented. A headset system includes a first earbud and a second earbud. One or both earbuds have a detector which indicates whether the earbud is donned or doffed. Operation of the headset is modified based on the donned or doffed status of the earbuds. | 07-26-2012 |
20130095894 | DONNED AND DOFFED HEADSET STATE DETECTION - An apparatus and method are provided for determining the donned or doffed state of a headset. In one example, a headset includes a processor, an acoustic transducer, and a detector operably coupled to the processor, the detector providing an output charge pattern corresponding to a state selected from the group consisting of the headset being donned and doffed. Advantageously, the present disclosure provides for reliably determining a donned or doffed state of a headset for efficiently routing calls, text messages, and/or otherwise being used for notifications and requests in a system. | 04-18-2013 |
20130188805 | Donned/Doffed Mute Control - Methods and apparatuses for headset wearing mode based operation are presented. A headset system includes a first earbud and a second earbud. One or both earbuds have a detector which indicates whether the earbud is donned or doffed. Operation of the headset is modified based on the donned or doffed status of the earbuds. | 07-25-2013 |
20130210497 | DONNED AND DOFFED HEADSET STATE DETECTION - An apparatus and method are provided for determining the donned or doffed state of a headset. In one example, a headset includes a processor, an acoustic transducer, and a detector operably coupled to the processor, the detector providing an output charge pattern corresponding to a state selected from the group consisting of the headset being donned and doffed. Advantageously, the present disclosure provides for reliably determining a donned or doffed state of a headset for efficiently routing calls, text messages, and/or otherwise being used for notifications and requests in a system. | 08-15-2013 |
20130300345 | Jaw Powered Electric Generator - An electric generator powered by the opening and closing of a user's jaw. In one embodiment, a portion of an electric generator is mechanically stressed by a user's teeth when the user opens or closes his jaw. The mechanical stress is converted to electric energy and may be stored in a battery or power an electric device. In another embodiment, a magnet is passed through a coil when the user opens or closes his jaw to generate electric energy. | 11-14-2013 |
Patent application number | Description | Published |
20110082627 | Morphing Vehicle User Interface - A method for operating a vehicle user interface is provided, the user interface utilizing a touch-screen display mounted within the vehicle. In one aspect, the visual or visual/interactive properties of the interface change after the user initiates interface interaction. In another aspect, the interface allows a user to utilize any of a variety of different control interaction techniques, all to achieve the same function. | 04-07-2011 |
20110296855 | Thermal Management System with Dual Mode Coolant Loops - A dual mode, thermal management system for use in a vehicle is provided. At a minimum, the system includes a first coolant loop in thermal communication with a battery system, a second coolant loop in thermal communication with at least one drive train component (e.g., electric motor, power electronics, inverter), and a dual mode valve system that provides means for selecting between a first mode where the two coolant loops operate in parallel, and a second mode where the two coolant loops operate in series. | 12-08-2011 |
20120153718 | Thermal Management System for Use with an Integrated Motor Assembly - An integrated drive system assembly is provided that combines an electric motor, a power inverter assembly and a gearbox into a single, multi-piece enclosure. Combining these components into a single enclosure reduces weight, reduces drive system complexity, reduces system volume, simplifies assembly integration into an electric vehicle, reduces manufacturing cost, allows the flexible and lengthy electrical cables between the power inverter and the electric motor to be replaced with short, low loss, rigid bus bars, and simplifies component cooling by allowing the use of a common thermal management system. The common thermal management system includes a liquid coolant loop that is thermally coupled to the electric motor, the power inverter assembly and the gearbox. | 06-21-2012 |
20120168125 | Multi-Function Automotive Radiator and Condenser Airflow System - A vehicle thermal management system is provided that includes two or more heat exchangers configured in a non-stacked arrangement, where separate air inlets corresponding to each of the heat exchangers allow a direct intake of ambient air. Corresponding to each heat exchanger is a set of adjustable louvers that control ambient air flowing directly into the heat exchanger. The adjustable louvers may be adjustable between two positions; fully opened or fully closed. Alternately, the adjustable louvers may be adjustable over a range between fully opened and fully closed. Alternately, each set of adjustable louvers may be comprised of multiple groups of independently controllable louvers. Air ducts may be used to couple the output from one heat exchanger to the input of a different heat exchanger. | 07-05-2012 |
20120180997 | Coolant De-Aeration Reservoir - A coolant de-aeration system is provided that includes a coolant reservoir, a plurality of de-aeration chambers within the reservoir, a plurality of de-aeration chamber apertures that direct coolant flow through the de-aeration chambers, a reservoir inlet and a reservoir outlet that share a common coolant flow pathway that allows the majority of coolant to flow directly between the reservoir inlet and the reservoir outlet, and a reservoir inlet aperture that directs a portion of coolant passing along the common coolant flow pathway through the reservoir's de-aeration chambers for de-aeration prior to being returned to the common coolant flow pathway. | 07-19-2012 |
20120183815 | Thermal Management System with Dual Mode Coolant Loops - A dual mode, thermal management system for use in a vehicle is provided. At a minimum, the system includes a first coolant loop in thermal communication with a battery system, a second coolant loop in thermal communication with at least one drive train component (e.g., electric motor, power electronics, inverter), a dual mode valve system that provides means for selecting between a first mode where the two coolant loops operate in parallel and a second mode where the two coolant loops operate in series, and a coolant reservoir that is coupled to both coolant loops when the two coolant loops are operating in series and only coupled to the drive train coolant loop when the two coolant loops are operating in parallel. | 07-19-2012 |
20120222833 | Active Louver System for Controlled Airflow in a Multi-Function Automotive Radiator and Condenser System - A vehicle thermal management system is provided that includes two or more heat exchangers configured in a non-stacked arrangement, where separate air inlets corresponding to each of the heat exchangers allow a direct intake of ambient air. Active louver systems consisting of sets of adjustable louvers and a control actuator are used to control and regulate air flowing directly into one or more of the heat exchangers, where the adjustable louvers are either adjustable between two positions, i.e., opened and closed, or adjustable over a range of positions. Air ducts may be used to couple the output from one heat exchanger to the input of a different heat exchanger. | 09-06-2012 |
20130074525 | Thermal Management System with Heat Exchanger Blending Valve - A thermal management system and method of use are provided, the system including a heat exchanger, a refrigeration system, a coolant loop thermally coupled to the heat exchanger, and a by-pass valve that regulates the amount of coolant within the coolant loop that either passes through the heat exchanger or is diverted away from the heat exchanger. The coolant loop is thermally coupled to the battery pack of an electric vehicle. | 03-28-2013 |
20130298583 | Battery Centric Thermal Management System Utilizing a Heat Exchanger Blending Valve - A method of regulating thermal dissipation from a vehicle battery pack is provided in which a by-pass valve is used to control the amount of battery pack coolant either passing through, or by-passing, a heat exchanger, where the coolant passing through the heat exchanger is cooled by a refrigeration system. The vehicle's HVAC system is controlled to insure that HVAC operation does not compromise maintaining the battery pack within an acceptable range of temperatures. | 11-14-2013 |
Patent application number | Description | Published |
20080263983 | Flush or near-flush flooring transitions - The invention is a joint cover assembly for covering a gap adjacent an edge of a panel that covers a sub-surface, and a method of covering such a gap. The assembly can be installed to be a flush or near-flush arrangement with adjacent flooring elements. | 10-30-2008 |
20100115870 | BREAK-AWAY MULTI-PURPOSE FLOORING TRANSITION - The invention is a joint cover assembly for covering a gap adjacent an edge of a panel that covers a sub-surface, and a method of covering such a gap. The assembly can be manipulated to form an end molding, a T-molding, a hard surface reducer, a carpet reducer, and/or a stair nose molding. A kit can include the joint cover assembly an a tool for forming a flooring transition from a generic element having break-away sections. | 05-13-2010 |
20120272602 | BREAK-AWAY MULTI-PURPOSE FLOORING TRANSITION - The invention is a joint cover assembly for covering a gap adjacent an edge of a panel that covers a sub-surface, and a method of covering such a gap. The assembly can be manipulated to form an end molding, a T-molding, a hard surface reducer, a carpet reducer, and/or a stair nose molding. | 11-01-2012 |
Patent application number | Description | Published |
20090058466 | DIFFERENTIAL PAIR CIRCUIT - A differential pair circuit includes a first transistor having a first control terminal, a first input terminal, and a first output terminal; a second transistor having a second control terminal, a second input terminal, and a second output terminal, a first buffer stage including a third transistor having a third control terminal, a third input terminal, and a third output terminal; and a second buffer stage including a fourth transistor having a fourth control terminal, a fourth input terminal, and a fourth output terminal. The first output terminal and the second output terminal are electrically connected; the third output terminal and the first control terminal are electrically connected; the fourth output terminal and the second control terminal are electrically connected; the first input terminal and the fourth input terminal are electrically connected; and the second input terminal and the third input terminal are electrically connected. | 03-05-2009 |
20130131665 | Transmural Ablation Device - A transmural ablation device is provided to achieve endocardial and epicardial ablation at the same site but directed from the inner and outer surfaces of the heart to create a transmural lesion. By ablating from both sides of the heart tissue, it is possible to increase the depth of the lesion created and to increase the likelihood of a transmural lesion. Embodiments pertain to techniques to align the endocardial and epicardial ablation elements and techniques to position and move the endocardial and epicardial ablation elements along a predefined linear, curvilinear, or circular path. The ability to bring the epicardial and endocardial elements more closely or firmly with the underlying tissue is important in creating optimal lesions. Magnetic force attracts the epicardial and endocardial elements. | 05-23-2013 |