Venturelli, IT
Alberto Venturelli, Maranello (modena) IT
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20120302511 | PEPTIDES BINDING TO THE DIMER INTERFACE OF THYMIDYLATE SYNTHASE FOR THE TREATMENT OF CANCER - Provided are peptides that bind to the thymidylate synthase protein, in particular to human thymidylate synthase (hTS) protein, for the treatment of cancer. Further provided are peptides that can bind at a binding site located at the interface of thymidylate synthase protein. These peptides range from 3 to 10, preferably 4-8 amino acids and have a sequence that binds to each subunit of the thymidylate synthase dimer at the level of dimer interface, stabilizing the dimeric inactive form of the thymidylate synthase enzyme. In addition, provided are pharmaceutical compositions including these compounds as active agents, and uses thereof for the treatment of cancer and to reverse or/and be active in cancer drug resistance. | 11-29-2012 |
Alberto Venturelli, Gorzano Di Maranello IT
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20100048692 | Naphthofuranone Derivatives as Specific Inhibitors of Thymidylate Synthases - Synthetic compounds of 1,2-naphthalein moelcules (I) having specific inhibitory properties of the enzymatic activity of thymidylate synthases of bacterial species, their preparation, their pharmaceutical composition and use in the treatment and prophylaxis of infectious pathologies are disclosed. | 02-25-2010 |
Andrea Venturelli, Brescia IT
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20080221662 | Endoluminal Prosthesis - An endoluminal prosthesis, comprising a tubular body, said tubular body developing along a longitudinal axis, said tubular body comprising a plurality of serpentines, which develop along a substantially circumpherential direction, each of said serpentines comprising arm portions of a preset width transversal to their main longitudinal extension, and bend portions joining two subsequent arms, at least one bridge, having a main longitudinal extension, connecting two adjacent serpentines, wherein the bends facing an adjacent serpentine are circumpherentially staggered relative to the opposite bends of the adjoining serpentine, both when the prosthesis is collapsed and when the prosthesis is expanded or partially expanded, wherein the at least one bridge connecting adjacent serpentines extends substantially straight, and wherein the at least one bridge has a width transversal to its main longitudinal direction of a greater value than the arm width. | 09-11-2008 |
20100070024 | Endoluminal Prosthesis - The present invention regards an endoluminal prosthesis ( | 03-18-2010 |
Andrea Venturelli, Concesio IT
Patent application number | Description | Published |
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20090069882 | Endoluminal Prosthesis - An endoluminal prosthesis comprises a tubular body which can be expanded about a longitudinal axis. A plurality of serpentines extend in a substantially circumferential direction. Each comprises arm portions and bend portions which join two subsequent arms. The bends facing an adjacent serpentine are circumferentially offset relative to the respective opposite bends of the contiguous serpentine, both when the prosthesis is collapsed and when the prosthesis is expanded. A first portion comprises at least two adjacent serpentines interconnected by at least one bridge, and at least two bends situated at the shortest longitudinal distance between the two serpentines is not connected by a bridge. A second portion comprises at least two adjacent serpentines interconnected by a number of bridges equal to the number of pairs of bends of the two serpentines, at the shortest longitudinal distance between the two serpentines. | 03-12-2009 |
20090198319 | Assembly for the Treatment of Bifurcations - A stent for the endoluminal treatment of stenosis at a vessel bifurcation comprises at least two cylindrical portions extending along different axes. A catheter and a mandrel for placing the stent are described as well. | 08-06-2009 |
20120253380 | Balloon for the treatment of stenosis and method for manufacturing the balloon - The present invention relates to a balloon ( | 10-04-2012 |
20140378896 | BALLOON FOR TREATMENT OF STENOSIS AND METHOD FOR MANUFACTURING THE BALLOON - The present invention relates to a balloon ( | 12-25-2014 |
Andrea Venturelli, Concesio (brescia) IT
Patent application number | Description | Published |
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20080215129 | Endolumenal Prosthesis with Bioresorbable Portions - The present invention relates to an endolumenal prosthesis comprising a tubular body adapted to convert from a contracted condition to an expanded condition. The tubular body develops along a longitudinal axis and comprises: a plurality of coils and at least one bridge. The coils develop along a substantially circumferential direction and the bridge connects two coils. The coils are realised in a persistent material, while the bridge is realised in a bioabsorbable material. | 09-04-2008 |
20080249484 | Auxiliary Probes - A first aspect of the invention relates to an auxiliary catheter comprising a main body comprising, in turn, a first duct defining a first lumen and a second duct defining a second lumen. Along the main body from the distal end in the proximal direction, the followings are found in the order: | 10-09-2008 |
Antonio Venturelli, Varese IT
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20100300296 | DEGASSER - Degasser including a shell and nozzles for spraying liquid into the shell, and plates within the shell to receive liquid sprayed by the nozzles. The plates disposed to enable running the liquid from upper plates to lower plates. The degasser including a port for steam entry into the shell and conveyor means for directing the steam between the plates. The steam is directed from the lower plates to the upper plates. The degasser including at least one first outlet to extract the degassed liquid from the degasser bottom and to enable a layer of degassed liquid to form on the container bottom when in use; and at least one second outlet to enable extracting a minimum part of the steam plus degassed gases from the shell interior. The conveyor means conveying entering steam to make it bubble through the layer of degassed liquid, to further reduce its dissolved gas concentration. | 12-02-2010 |
Leonardo Venturelli, Calderara Di Reno (bologna) IT
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20160040166 | OLIGONUCLEOTIDES FOR MODULATING GENE EXPRESSION AND USES THEREOF - The present invention regards oligonucleotides for modulating the expression of a gene, in particular for modulating a gene responsible for a pathology of genetic, tumoural or viral origin. Moreover, the present invention relates to the use of said oligonucleotides, possibly chemically modified, for the treatment and/or the diagnosis of said diseases. | 02-11-2016 |
Matteo Venturelli, Serramazzoni IT
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20140329642 | METHOD FOR CALIBRATING A DETECTOR IN A DAMPING ASSEMBLY - A method for calibrating a detector of a damping assembly in a vehicle is disclosed. The damping assembly comprises a damper for connecting a transmission shaft of a transmission system of the vehicle to a driving shaft, the method comprising the step of applying different torques at the damping assembly by generating losses at different working conditions of the transmission system, so that the damper can be compared to a damper of a reference vehicle for each of said different working conditions. | 11-06-2014 |
Matteo Venturelli, Serramazzoni (modena) IT
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20090033010 | Method and a jig for mounting a stack of Belleville Springs - The invention relates to mounting of a stack of Belleville springs about a shaft. The individual springs of the stack are first positioned over the shaft. A jig is then placed over the shaft and the springs and has at least one axially extending pressure bar that is radially inwardly biased to urge the inner circumferences of all the springs into contact with axially aligned points on the surface of the shaft. The springs are then compressed using a compression element while they are still urged by the pressure bar against the shaft. Finally, to retain the springs on the shaft and maintain the springs in compression, a split retaining clip is pressed onto to the shaft until it engages in a groove. | 02-05-2009 |
20120291244 | Jig for Mounting a Stack of Belleville Springs - The invention relates to mounting of a stack of Belleville springs about a shaft. The individual springs of the stack are first positioned over the shaft. A jig is then placed over the shaft and the springs and has at least one axially extending pressure bar that is radially inwardly biased to urge the inner circumferences of all the springs into contact with axially aligned points on the surface of the shaft. The springs are then compressed using a compression element while they are still urged by the pressure bar against the shaft. Finally, to retain the springs on the shaft and maintain the springs in compression, a split retaining clip is pressed onto to the shaft until it engages in a groove. | 11-22-2012 |
20150314788 | A Method for Estimating Torque Downstream of a Vehicle Transmission - A method for estimating torque transmitted to a structure located downstream of a transmission system of a vehicle is disclosed. The vehicle comprises an engine for generating torque, a transmission system configured to transmit a fraction of the torque generated by the engine to a plurality of wheels of the vehicle, and a further fraction of the torque generated by the engine to the structure. The transmission system includes a shaft arrangement interposed between the engine and the structure, a planetary gearing supported by the shaft arrangement, and a transmission unit arranged in parallel to the shaft arrangement. The torque transmitted to the structure is estimated on the basis of a group of parameters which comprise torque upstream of the transmission system, twist of the shaft arrangement, and a parameter which is indicative of the ratio between an output rotational speed at an output of the transmission unit and an input rotational speed at an input of the transmission unit. | 11-05-2015 |