Johannes Theodorus
Johannes Theodorus Antonius Van De Ven, Eindhoven NL
Patent application number | Description | Published |
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20140159407 | ROBOTIC FINGER - A prosthetic finger, comprising: a first axis of movement comprising a moving magnet; a second axis of movement comprising a moving coil, wherein the second axis is generally orthogonal to the first axis; and a third axis of movement comprising a moving magnet, wherein the third axis of movement is generally oriented in the same direction as the first axis of movement. | 06-12-2014 |
20140159408 | ROBOTIC FINGER - A robotic finger, comprising: a first axis of movement comprising a moving magnet; a second axis of movement comprising a moving coil, wherein the second axis is generally orthogonal to the first axis; and a third axis of movement comprising a moving magnet, wherein the third axis of movement is generally oriented in the same direction as the first axis of movement. | 06-12-2014 |
Johannes Theodorus Den Dunnen, Rotterdam NL
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20080209581 | Induction of exon skipping in eukaryotic cells - Described is a method for at least in part decreasing the production of an aberrant protein in a cell, the cell comprising pre-mRNA comprising exons coding for the protein, by inducing so-called exon skipping in the cell. Exon-skipping results in mature mRNA that does not contain the skipped exon, which leads to an altered product of the exon codes for amino acids. Exon skipping is performed by providing a cell with an agent capable of specifically inhibiting an exon inclusion signal, for instance, an exon recognition sequence, of the exon. The exon inclusion signal can be interfered with by a nucleic acid comprising complementarity to a part of the exon. The nucleic acid, which is also herewith provided, can be used for the preparation of a medicament, for instance, for the treatment of an inherited disease. | 08-28-2008 |
20100125099 | THERAPEUTIC INTERVENTION IN A GENETIC DISEASE IN AN INDIVIDUAL BY MODIFYING EXPRESSION OF AN ABERRANTLY OR ABNORMALLY EXPRESSED GENE - The present invention provides means and methods for alleviating genetic disease. A genetic defect that has a phenotype in differentiated cells can lead to defects in precursor cells thereof. These so-called secondary defects contribute to the overall disease of the individual. In the present invention, genetic intervention with the aim to alleviate symptoms of genetic disease is directed toward the primary genetic defect in the differentiated cell and the secondary defect in the precursor cell. | 05-20-2010 |
20140357698 | MODULATION OF EXON RECOGNITION IN PRE-MRNA BY INTERFERING WITH THE SECONDARY RNA STRUCTURE - The invention relates to oligonucleotides for inducing skipping of exon 53 of the dystrophin gene. The invention also relates to methods of inducing exon 53 skipping using the oligonucleotides. | 12-04-2014 |
20140357855 | MODULATION OF EXON RECOGNITION IN PRE-MRNA BY INTERFERING WITH THE SECONDARY RNA STRUCTURE - The invention relates to oligonucleotides for inducing skipping of exon 53 of the dystrophin gene. The invention also relates to methods of inducing exon 53 skipping using the oligonucleotides. | 12-04-2014 |
Johannes Theodorus Huiberts, Spanbroek NL
Patent application number | Description | Published |
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20140041527 | BEVERAGE PREPARATION DEVICE - The invention relates to a beverage preparation device comprising a cylindrical chamber with a jacket provided with a filling opening for receiving a powder-like or granular substance and an ejection opening for ejecting the substance, a first and a second compression element, positioned perpendicularly with respect to a longitudinal axis of the chamber, a displacement member for relative displacement of the first compression element with respect to the jacket between a filling position, a compression position and an ejection position, wherein the compression elements in the filling position delimit a filling volume and the compression elements in the compression position delimit a preparation volume positioned along a longitudinal axis and at a distance from the filling volume, wherein the first compression element engages the inner wall of the jacket in a fluid-tight manner and a fluid supply channel and a fluid discharge channel that in the compression position is in fluid-communication with the preparation volume. | 02-13-2014 |