Patent application number | Description | Published |
20100032223 | DRIFTING KART - Drifting karts in accordance with embodiments of the invention are described that include a front wheel drive train and rear caster wheels that can be dynamically engaged to induce and control drift during a turn. One embodiment of the invention includes a chassis to which a steering column is mounted, where the steering column includes at least one front steerable wheel configured to be driven by an electric motor, a battery housing mounted to the chassis, where the battery housing contains a controller and at least one battery, wiring configured to provide power from the at least one battery to the electric motor, two caster wheels mounted to the chassis, where each caster wheel is configured to rotate around a rotational axis and swivel around a swivel axis, and a hand lever configured to dynamically engage the caster wheels to induce and control drift during a turn. | 02-11-2010 |
20110042912 | DRIFTING KART - Drifting karts in accordance with embodiments of the invention are described that include a front wheel drive train and rear caster wheels that can be dynamically engaged to induce and control drift during a turn. One embodiment of the invention includes a chassis to which a steering column is mounted, where the steering column includes at least one front steerable wheel configured to be driven by an electric motor, a battery housing mounted to the chassis, where the battery housing contains a controller and at least one battery, wiring configured to provide power from the at least one battery to the electric motor, two caster wheels mounted to the chassis, where each caster wheel is configured to rotate around a rotational axis and swivel around a swivel axis, and a hand lever configured to dynamically engage the caster wheels to induce and control drift during a turn. | 02-24-2011 |
20130199861 | DRIFTING KART - Drifting karts in accordance with embodiments of the invention are described that include a front wheel drive train and rear caster wheels that can be dynamically engaged to induce and control drift during a turn. One embodiment of the invention includes a chassis to which a steering column is mounted, where the steering column includes at least one front steerable wheel configured to be driven by an electric motor, a battery housing mounted to the chassis, where the battery housing contains a controller and at least one battery, wiring configured to provide power from the at least one battery to the electric motor, two caster wheels mounted to the chassis, where each caster wheel is configured to rotate around a rotational axis and swivel around a swivel axis, and a hand lever configured to dynamically engage the caster wheels to induce and control drift during a turn. | 08-08-2013 |
Patent application number | Description | Published |
20100199155 | METHOD AND APPARATUS FOR QUANTIFICATION OF DNA SEQUENCING QUALITY AND CONSTRUCTION OF A CHARACTERIZABLE MODEL SYSTEM USING REED-SOLOMON CODES - Data extracted from fluorosphore responses of fluorophore labeled bases in genetic material used in sequencing of unknown fragments from a defined set of for example a model system are converted into a class of block codes that are then employed in a computer-based process to compare and correct preliminary calls of calls of the categorically known genetic material. In a specific embodiment, the Reed-Solomon codes are employed to identify one or more errors as may occur in a finite block of codes. The methodology is also useful to identify elements of a real system containing known elements in the form of a tag. Reed-Solomon sensors may be employed with and in addition to other types of genome sensors. | 08-05-2010 |
20100261983 | IMPLANTABLE DEVICES FOR DYNAMIC MONITORING OF PHYSIOLOGICAL AND BIOLOGICAL PROPERTIES OF TUMORS - Biocompatible sensors configured for implantation include a first body in communication with a plurality of remote sensor bodies to detect physiological parameters in vivo. | 10-14-2010 |
20130054151 | PHASING OF HETEROZYGOUS LOCI TO DETERMINE GENOMIC HAPLOTYPES - Haplotypes of one or more portions of a chromosome of an organism from sequencing information of DNA or RNA fragments can be determined. Heterozygous loci (hets) can be used to determine haplotypes. One allele on a first het can be connected (likely to be on the same haplotype) to an allele on a second het, thereby defining a particular orientation between the hets. Haplotypes can be assembled through these connections. Errors can be identified through redundant connection information, particularly using a confidence value (strength) for a particular connection. The connections among a set of hets can be analyzed to determine likely haplotypes for that set, e.g., an optimal tree of a graph containing the hets. Furthermore, haplotypes of different contiguous sections (contig) of the chromosome can be matched to a particular chromosome copy (e.g., to a particular parental copy). Thus, the phase of an entire chromosome can be determined. | 02-28-2013 |
20130054508 | ANALYZING GENOME SEQUENCING INFORMATION TO DETERMINE LIKELIHOOD OF CO-SEGREGATING ALLELES ON HAPLOTYPES - Sequencing information is used to correlate alleles at certain locations to alleles at other locations. The statistical information from the reads of fragments in a sample can be used to determine the phasing of haplotypes and to correct or confirm based calls at the locations. In one example, a confidence value (strength score) is determined for a particular hypothesis, which can include whether two alleles are on a same haplotype at two particular loci, as well as what the alleles are on another haplotype (e.g. for a diploid organism). The strength can include a positive contribution from data that is consistent with the hypothesis and a negative contribution from data is that inconsistent with the hypothesis, where both values can be used in a formula to determine the strength. | 02-28-2013 |
20130059740 | Sequencing Small Amounts of Complex Nucleic Acids - The present invention provides methods and compositions for sequencing small amounts of complex nucleic acids such as human genomes and for analyzing the resulting sequence information in order to reduce sequencing errors and perform haplotype phasing, for example. | 03-07-2013 |
20130096841 | IDENTIFICATION OF DNA FRAGMENTS AND STRUCTURAL VARIATIONS - Various short reads can be grouped and identified as coming from a same long DNA fragment (e.g., by using wells with a relatively low-concentration of DNA). A histogram of the genomic coverage of a group of short reads can provide the edges of the corresponding long fragment (pulse). The knowledge of these pulses can provide an ability to determine the haploid genome and to identify structural variations. | 04-18-2013 |
20130124100 | Processing and Analysis of Complex Nucleic Acid Sequence Data - The present invention is directed to logic for analysis of nucleic acid sequence data that employs algorithms that lead to a substantial improvement in sequence accuracy and that can be used to phase sequence variations, e.g., in connection with the use of the long fragment read (LFR) process. | 05-16-2013 |
20140051588 | Sequencing Small Amounts of Complex Nucleic Acids - The present invention provides methods and compositions for sequencing small amounts of complex nucleic acids such as human genomes and for analyzing the resulting sequence information in order to reduce sequencing errors and perform haplotype phasing, for example. | 02-20-2014 |
20150057947 | LONG FRAGMENT DE NOVO ASSEMBLY USING SHORT READS - Techniques perform de novo assembly. The assembly can use labels that indicate origins of the nucleic acid molecules. For example, a representative set of labels identified from initial reads that overlap with a seed can be used. Mate pair information can be used. A sequence read that aligns to an end of a contig can lead to using the other sequence read of a mate pair, and the other sequence read can be used to determine which branch to use to extend, e.g., in an external cloud or helper contig. A kmer index can include labels indicating an origin of each of the nucleic acid molecules that include each kmer, memory addresses of the reads that correspond to each kmer in the index, and a position in each of the mate pairs that includes the kmer. Haploid seeds can also be determined using polymorphic loci identified in a population. | 02-26-2015 |
Patent application number | Description | Published |
20090027040 | OPEN CIRCUIT DELAY DEVICES, SYSTEMS, AND METHODS FOR ANALYTE MEASUREMENT - System, circuits, and methods to reduce or eliminate uncompensated voltage drop between an electrode of an electrochemical cell usable for analyte measurement. In one example, a system is provided that includes a test strip, a reference voltage circuit, an operational amplifier connected to the reference voltage circuit to provide a predetermined fraction of a reference voltage substantially equal to the test voltage applied to the first line, the operational amplifier having an output configured for one of a connected or disconnected state to the first line, and a processing circuit connected to the output of the operational amplifier and the first line such that, during a disconnected state between the output and the first line, the processing circuit remains in connection with the first line. In another example, a method of measuring an electrochemical reaction of an electrochemical cell is provided that includes applying a test voltage to the first electrode and connecting the second electrode to ground; uncoupling the first electrode from the output of the circuit while allowing electrical communication from the first electrode to the processor; and coupling the first electrode to the output to measure a test current generated in the electrochemical cell without an uncompensated voltage drop. | 01-29-2009 |
20090029479 | TEST STRIP AND CONNECTOR - An analyte test strip is provided that includes a generally planar substrate and a plurality of conductive areas disposed on the substrate to define five distinct conductive portions comprising at least five contact lands defining respective vertices of a polygon, and in which two contact lands are located in a single conductive portion. System and method utilizing the test strip are also described. | 01-29-2009 |
20090043177 | METHOD FOR INTEGRATING FACILITATED BLOOD FLOW AND BLOOD ANALYTE MONITORING - A method for the integrated facilitization of blood flow and monitoring of blood analyte concentration (for example, blood glucose concentration) includes implanting a stent configured to facilitate blood flow into a cardiovascular system of a user's body with the stent having attached thereto a continuous blood analyte determination module of a blood analyte monitoring system. The method also includes disposing a reader module of the blood analyte monitoring system external to the user's body and in proximity to a portion of the user's skin layer and monitoring blood analyte concentration via (i) emitting an RF carrier signal from the reader module toward the stent; (ii) receiving the RF carrier signal at a reflection antenna of the continuous blood analyte determination module; (iii) reflecting a modulated signal by the reflection antenna with the modulated signal being encoded with a blood analyte concentration determined by a sensor of the continuous blood analyte determination module; (iv) receiving the modulated signal by the reader module; and (v) decoding the analyte concentration from the modulated signal by the reader module. | 02-12-2009 |
20090043183 | INTEGRATED STENT AND BLOOD ANALYTE MONITORING SYSTEM - An integrated stent and blood analyte monitoring system includes a stent configured for implantation into a cardiovascular system of a user's body and a blood analyte monitoring system. The blood analyte monitoring system includes a continuous blood analyte determination module attached to the stent and a reader module configured for disposition external to the user's body and proximal to a portion of the user's skin layer. The continuous blood analyte determination module has a sensor for determining the concentration of a blood analyte (e.g., blood glucose concentration) and a reflection antenna with a switch. The reader module is configured to emit an RF carrier signal toward the stent. The reflection antenna is configured to receive the RF carrier signal and reflect a modulated signal that has been modulated by the switch to encode an analyte concentration determined by the sensor. Furthermore, the reader module is configured to receive the modulated signal and decode the analyte concentration therefrom. | 02-12-2009 |
20100128754 | Multiple Temperature Measurements Coupled With Modeling - The present invention is directed to, inter alia, systems and methods for calculating a temperature associated with an analyte measurement component of a biosensing instrument (such as a blood glucose monitor), with a test strip that is inserted in a biosensing instrument, or both. The present systems and methods may employ at least two temperature sensors, and the acquired temperature information may be used to modulate data regarding an analyte in a biological sample, thereby providing a more accurate measurement of the analyte. | 05-27-2010 |
20100130838 | Infrared Temperature Measurement of Strip - Provided are systems and methods that permit the direct assessment of temperature on an electrochemical test strip, including at the reaction site of the strip, through the inclusion of an infrared sensor within the biosensing instrument. Analyte measurement systems are provided in which an infrared sensor is used to assess temperature associated with a test strip, and the acquired temperature data is used to modulate data regarding an analyte in a biological sample, thereby providing a more accurate measurement of the analyte. | 05-27-2010 |
20130039383 | MULTIPLE TEMPERATURE MEASUREMENTS COUPLED WITH MODELING - The present invention is directed to, inter alia, systems and methods for calculating a temperature associated with an analyte measurement component of a biosensing instrument (such as a blood glucose monitor), with a test strip that is inserted in a biosensing instrument, or both. The present systems and methods may employ at least two temperature sensors, and the acquired temperature information may be used to modulate data regarding an analyte in a biological sample, thereby providing a more accurate measurement of the analyte. | 02-14-2013 |