Patent application number | Description | Published |
20100313960 | High Performance Transducer - An electro-pneumatic transducer for controlling gas pressure is disclosed. The transducer includes a nozzle body and a valve housing interconnected therebetween by a nozzle and a solenoid assembly including a magnetized valve assembly and a solenoid having a top portion and a bottom portion, which when energized generate a magnetic field having a predetermined polarity in response to which the magnetized valve assembly is actuated to control gas flow through the nozzle. The transducer also includes a control circuit adapted to receive an input signal. The control circuit is configured to energize the solenoid in response to the input signal to generate the magnetic field thereabout to actuate the valve assembly. The transducer further includes a capacitor coupled to the control circuit, wherein upon loss of the input signal, the control circuit signals the capacitor to provide an electrical signal to the solenoid to actuate the valve assembly. | 12-16-2010 |
20110284788 | High Performance Miniature Regulator - A pressure regulator is disclosed. The pressure regulator includes a housing having a supply port and an outlet port interconnected by an opening defined in a sealing seat. The pressure regulator also includes a supply valve assembly having a core and an elastic shell disposed thereon, wherein the elastic shell is configured to seal the opening and a diaphragm assembly biased by a range spring and configured to push on the supply valve, the diaphragm assembly having a working surface area. | 11-24-2011 |
20130233406 | Systems And Methods For A Three Chamber Compensation Network - Systems and methods for a three chamber compensation network for pressure regulators are disclosed. For example, one described pressure regulator includes: an inlet port; a primary chamber coupled to the inlet port by a main valve; an outlet chamber coupled to the primary chamber by one or more venturi; and a control chamber coupled to one or more of the venturi by one or more sensing holes, the control chamber comprising a movable piston configured to vary the position of the main valve. | 09-12-2013 |
20140034155 | Valve Seat For A Pressure Regulator - Improved valve seats for pressure regulators, as well as improved pressure regulators, are disclosed. For example, in one disclosed embodiment, a valve seat may comprise a first valve seat surface; a second valve seat surface opposite the first valve seat surface; a compression seal area; and a concentric stress relief groove on the first valve seat surface. | 02-06-2014 |
Patent application number | Description | Published |
20130151481 | SYSTEM, APPARATUS AND METHOD FOR GENERATING ARRANGEMENTS OF DATA BASED ON SIMILARITY FOR CATALOGING AND ANALYTICS - Embodiments of the invention relate generally to electrical and electronic hardware, computer software, wired and wireless network communications, and computing devices, and more particularly, to a system, an apparatus and a method configured to generate arrangements of data, including data catalogs, to facilitate discovery of items via an interface depicting item representations based on similarity of one or more attributes. In one embodiment, a method includes receiving data representing a request to transmit data; executing instructions at a processor to determine the relationships of the item representations to the principal item representation for records stored in a memory, associating the item representations to positions of a data arrangement based on the relationships of the item representations. Also the method can include transmitting to a computing device data representing the data arrangement including data representing the item representations to be presented on an interface of the computing device. | 06-13-2013 |
20130152019 | APPARATUS AND METHOD FOR FACILITATING DISCOVERY OF ITEMS VIA AN INTERFACE DEPICTING SELECTABLE REPRESENTATIONS BASED ON SIMILARITY - Embodiments of the invention relate generally to electrical and electronic hardware, computer software, wired and wireless network communications, and computing devices, and more particularly, to an apparatus and methods configured to facilitate discovery of items via an interface, such as a touchscreen interface, depicting item representations based on similarity of one or more attributes. | 06-13-2013 |
Patent application number | Description | Published |
20090054460 | Piperazine derivatives and methods of use - Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation, and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes. | 02-26-2009 |
20140221410 | Fluorinated 3-(2-Oxo-3-(3-Arylpropyl)Imidazolidin-1-yl)-3-Arylpropanoic Acid Derivatives - The invention relates to fluorinated compounds and their use as integrin receptor antagonists. Novel fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives and pharmaceutically acceptable salts or solvates thereof and their use are described. | 08-07-2014 |
20140235634 | THERAPEUTIC COMPOUNDS AND USES THEREOF - Described herein are compounds of Formula (I) or Formula (VI), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Also provided are particles (e.g., nanoparticles) comprising compounds of Formula (I) or Formula (VI) and pharmaceutical compositions thereof that are mucus penetrating. Methods of using the compounds or pharmaceutical compositions thereof for treating diseases are also provided. | 08-21-2014 |
20140235657 | THERAPEUTIC COMPOUNDS AND USES THEREOF - Described herein are compounds of Formula (I)-(III), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Also provided are particles (e.g., nanoparticles) comprising compounds of Formula (I)-(III) and pharmaceutical compositions thereof that are mucus penetrating. Methods of using the compounds or pharmaceutical compositions thereof for treating and/or preventing diseases are also provided. | 08-21-2014 |
20140296260 | 3-Aryl-2-((Arylamino)Methyl)Quinazolin-4-(3H)-Ones - The invention relates to novel quinazolinone compounds and their use as inhibitors of PI3 kinases, for example, PI3Kδ, for treating and/or preventing diseases, disorder, and conditions associated with modulating PI3 kinase activity. Novel 3-aryl-2-((arylamino)methyl)quinazolin-4(3H)-one derivatives and pharmaceutically acceptable salts or solvates thereof and their use for the treatment or prevention of diseases, disorders, and conditions associated with the activity of one or more PI3 kinase, such as PI3Kδ, are disclosed. | 10-02-2014 |
20150057308 | Fluorinated 3-(2-Oxo-3-(3-Arylpropyl)Imidazolidin-1-yl)-3-Arylpropanoic Acid Derivatives - The invention relates to fluorinated compounds and their use as integrin receptor antagonists. Novel fluorinated 3-(2-oxo-3-(3 -arylpropyl)imidazolidin-1-yl)-3 -arylpropanoic acid derivatives and pharmaceutically acceptable salts or solvates thereof and their use are described. | 02-26-2015 |
Patent application number | Description | Published |
20080283328 | LONGITUDINAL STRINGER EXHAUST FLEX PIPE ASSEMBLY - A longitudinal stringer type exhaust flex pipe assembly is provided having two end pieces and multiple interlaced interlocking longitudinal stringer elements forming a flexible cylinder. Every other longitudinal stringer element is affixed to each end piece, such that each stringer element is affixed to only one end piece. The stringer elements each have a male and a female interlocking feature that allows them to slide freely between each other while maintaining a relatively airtight seal. This provides a flex pipe assembly that is compliant in the compression, extension, axial bending, and torsional directions. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. 37 CFR 1.72(b). | 11-20-2008 |
20110126524 | ENGINE EXHAUST SYSTEM HAVING A PLURALITY OF DIESEL PARTICULATE FILTERS - An exhaust system for an internal combustion engine comprises a turbocharger, an exhaust pipe, a first diesel particulate filter, a second diesel particulate filter, and a flow control valve. The exhaust pipe has a first portion, a second portion, and a third portion. At least the second portion of the exhaust pipe comprises a plurality of fluid paths. The first diesel particulate filter is coupled to on one of the plurality of fluid paths between the second portion and the third portion of the exhaust pipe. The second diesel particulate filter is coupled to another of the plurality of fluid paths. The flow control valve is disposed within the second portion of the exhaust pipe. The flow control valve is response to an input signal indicative of an operating condition and is configured to control exhaust flow to the first diesel particulate filter and the second diesel particulate filter in response to the input signal. | 06-02-2011 |
20120222412 | Engine Exhaust Gas Particulate Filter having Helically Configured Cells - An engine exhaust gas particulate filter comprises a plurality of paired longitudinal flow cells having a first flow cell channel and a second flow cell channel. The first flow cell channel is disposed in fluid communication with the second flow cell channel through a common permeable filtration wall. Each of the plurality of paired longitudinal flow cells forms a non-linear flow path about a longitudinal axis of the engine exhaust gas particulate filter. | 09-06-2012 |
20120275039 | AUTOMATICALLY ADJUSTING SIDE MIRROR ASSEMBLY FOR A VEHICLE - An automatically adjusting side mirror assembly for a vehicle having an eye gaze detection system has a mirror subassembly, a support bracket, an actuator mechanism and a biasing mechanism. The mirror subassembly has a first and second position. The second position aligns the mirror subassembly generally parallel to the vehicle in order to provide better aerodynamics. The support bracket connects to the vehicle. The mirror subassembly is connected to the support bracket. The actuator mechanism and the biasing mechanism each connects to the mirror subassembly. The actuator mechanism has a first and second position corresponding to the first and second position of the mirror subassembly. The actuator mechanism is in electrical communication with the eye gaze detection system to position the mirror subassembly to the first position in response to an output of the eye gaze detection system. The biasing mechanism biases the mirror subassembly to the first position. | 11-01-2012 |
Patent application number | Description | Published |
20150110721 | Modulation of a Response Signal to Distinguish Between Analyte and Background Signals - A method for modulating a response signal includes introducing functionalized particles into a lumen of subsurface vasculature, wherein the functionalized particles are configured to interact with one or more target analytes present in blood circulating in the subsurface vasculature; and non-invasively detecting the one or more target analytes. A response signal, which may include a background signal and an analyte response signal related to interaction of the functionalized particles with the one or more target analytes, is transmitted from the subsurface vasculature. A modulation configured to alter the response signal such that the analyte response signal is affected differently than the background signal may be applied to a portion of subsurface vasculature. Analyte detection may be achieved by differentiating the analyte response signal from the background signal. | 04-23-2015 |
20150112167 | Non-Invasive Analyte Detection System with Modulation Source - A system for modulating a response signal includes functionalized particles configured to interact with target analytes, a detector configured to detect an analyte response signal transmitted from the body, a modulation source configured to modulate the analyte response signal, and a processor configured to non-invasively detect the one or more target analytes by differentiating the analyte response signal from a background signal, at least in part, based on the modulation. The analyte response signal is related to the interaction of the target analytes with the functionalized particles. In some examples, the system may also include magnetic particles and a magnetic field source sufficient to distribute the magnetic particles into a spatial arrangement in the body. The analyte response signal may be differentiated from the background signal, at least in part, based on modulation of the signals due, at least in part, to the spatial arrangement of the magnetic particles. | 04-23-2015 |
20150112168 | Spatial Modulation of Magnetic Particles in Vasculature by External Magnetic Field - A method for modulating a response signal includes introducing functionalized magnetic particles configured to interact with target analytes into the body, applying a magnetic field sufficient to draw the functionalized magnetic particles towards a surface of the lumen of subsurface vasculature closest to an internally or externally applied mask having a spatial arrangement, and detecting a response signal, which includes a background signal and an analyte response signal, transmitted from the subsurface vasculature. The analyte response signal related to interaction of the functionalized magnetic particles with the target analytes and is modulated with respect to the background signal due, at least in part, to the spatial arrangement of the mask. The target analytes may be non-invasively detected by differentiating the analyte response signal from the background signal due, at least in part, to the modulation of the analyte response signal. | 04-23-2015 |
Patent application number | Description | Published |
20120184609 | VITAMIN C AND VITAMIN K, AND COMPOSITIONS THEREOF FOR TREATMENT OF OSTEOLYSIS OR PROLONGATION OF PROSTHETIC IMPLANT - Provided herein is a method of treating, preventing, or managing osteolysis in a subject, comprising administering to the subject a therapeutically effective amount of vitamin C, or a pharmaceutically acceptable salt, solvate, or hydrate thereof, in combination with vitamin K, or a single enantiomer, a mixture of enantiomers, or a mixture of diastereomers thereof, or a pharmaceutically acceptable salt, solvate, or hydrate thereof. | 07-19-2012 |
20130178522 | VITAMIN C AND CHROMIUM-FREE VITAMIN K, AND COMPOSITIONS THEREOF FOR TREATING AN NFKB-MEDIATED CONDITION OR DISEASE - Provided herein is a pharmaceutical composition comprising vitamin C and chromium-free vitamin K, and optionally one or more pharmaceutically acceptable excipient(s). Also provided herein is a chromium-free pharmaceutical composition comprising vitamin C and vitamin K, and optionally one or more pharmaceutically acceptable excipient(s). Further provided herein is a method of treating, preventing, or managing an NFKB-mediated condition, disorder, or disease, comprising administering to the subject a therapeutically effective amount of vitamin C and chromium-free vitamin K. | 07-11-2013 |
Patent application number | Description | Published |
20110067521 | HUMANOID ROBOT - A humanoid robot includes a torso, a pair of arms, two hands, a neck, and a head. The torso extends along a primary axis and presents a pair of shoulders. The pair of arms movably extend from a respective one of the pair of shoulders. Each of the arms has a plurality of arm joints. The neck movably extends from the torso along the primary axis. The neck has at least one neck joint. The head movably extends from the neck along the primary axis. The head has at least one head joint. The shoulders are canted toward one another at a shrug angle that is defined between each of the shoulders such that a workspace is defined between the shoulders. | 03-24-2011 |
20110068595 | ROBOTIC FINGER ASSEMBLY - A robotic hand includes a finger with first, second, and third phalanges. A first joint rotatably connects the first phalange to a base structure. A second joint rotatably connects the first phalange to the second phalange. A third joint rotatably connects the third phalange to the second phalange. The second joint and the third joint are kinematically linked such that the position of the third phalange with respect to the second phalange is determined by the position of the second phalange with respect to the first phalange. | 03-24-2011 |
20110071671 | DEXTEROUS HUMANOID ROBOTIC WRIST - A humanoid robot includes a torso, a pair of arms, a neck, a head, a wrist joint assembly, and a control system. The arms and the neck movably extend from the torso. Each of the arms includes a lower arm and a hand that is rotatable relative to the lower arm. The wrist joint assembly is operatively defined between the lower arm and the hand. The wrist joint assembly includes a yaw axis and a pitch axis. The pitch axis is disposed in a spaced relationship to the yaw axis such that the axes are generally perpendicular. The pitch axis extends between the yaw axis and the lower arm. The hand is rotatable relative to the lower arm about each of the yaw axis and the pitch axis. The control system is configured for determining a yaw angle and a pitch angle of the wrist joint assembly. | 03-24-2011 |
20110071673 | ACTUATOR AND ELECTRONICS PACKAGING FOR EXTRINSIC HUMANOID HAND - The lower arm assembly for a humanoid robot includes an arm support having a first side and a second side, a plurality of wrist actuators mounted to the first side of the arm support, a plurality of finger actuators mounted to the second side of the arm support and a plurality of electronics also located on the first side of the arm support. | 03-24-2011 |
20110071678 | TENDON DRIVEN FINGER ACTUATION SYSTEM - A humanoid robot includes a robotic hand having at least one finger. An actuation system for the robotic finger includes an actuator assembly which is supported by the robot and is spaced apart from the finger. A tendon extends from the actuator assembly to the at least one finger and ends in a tendon terminator. The actuator assembly is operable to actuate the tendon to move the tendon terminator and, thus, the finger. | 03-24-2011 |
20130193704 | ROBOTIC FINGER ASSEMBLY - A robotic hand includes a finger with first, second, and third phalanges. A first joint rotatably connects the first phalange to a base structure. A second joint rotatably connects the first phalange to the second phalange. A third joint rotatably connects the third phalange to the second phalange. The second joint and the third joint are kinematically linked such that the position of the third phalange with respect to the second phalange is determined by the position of the second phalange with respect to the first phalange. | 08-01-2013 |
Patent application number | Description | Published |
20090157002 | CATHETER HAVING COMMUNICATING LUMENS - A catheter having a plurality of longitudinal lumens for removing biological, natural and/or man-made materials from cavities, ducts, vessels, or other locations in a patient's body. The multi-lumen catheter comprises a longitudinally-extending suction lumen with suction holes through which materials pass into the lumen in response to suction forces generated by a source of negative pressure coupled to a proximal end of the lumen. A longitudinally-extending vent lumen coupled to a source of at least neutral vent pressure through, for example, an opening to ambient air at the proximal end of the lumen, and preferably, through vent holes disposed along a length of the catheter. A dividing septum between the adjacent lumens has one or more ports fluidically coupling the lumens. The ratio of the area of the suction holes and ports is such that the suction force at unobstructed suction holes is maintained below a desired maximum force for a given negative pressure when none or more of the suctions holes are obstructed. When a suction hole obstruction occurs, fluid is drawn into the suction lumen through the communication port(s). This compensating fluid flow prevents the suction forces from exceeding a predetermined maximum value during use even when one or more suction holes become obstructed. This maximum force may be set, for example, to avoid hematoma, to permit repositioning of the catheter during use, etc. thereby allowing for continuous suction. | 06-18-2009 |
20090192504 | CRYOSURGERY SYSTEM HAVING UNINTEGRATED DELIVERY AND VISUALIZATION APPARATUS - Systems and methods for delivering cryosurgical treatment. The cryosurgery system comprises a cryogen delivery apparatus configured to deliver a spray of cryogen to target tissue of a patient and an indirect visualization apparatus configured to provide indirect visualization of the target tissue during the cryogen delivery. The indirect visualization apparatus and the cryogen delivery apparatus are constructed and arranged to be operationally unintegrated and physically spaced with respect to each other during the delivery of the cryogen. | 07-30-2009 |
20090192505 | Method for cryospray ablation - The present invention relates to methods for treating tissue in the thoracic cavity of a subject by the application of a cryogen, or using the cryogen to create an isotherm in proximity to the tissue to be treated. A wide variety of conditions may be treated using the methods of the invention including asthma, neoplastic disease and a variety of conditions characterized by inflammation in lung and chest tissue. | 07-30-2009 |
20110208166 | CATHETER HAVING COMMUNICATING LUMENS - A catheter having a plurality of longitudinal lumens for removing biological, natural and/or man-made materials from cavities, ducts, vessels, or other locations in a patient's body. The multi-lumen catheter comprises a longitudinally-extending suction lumen with suction holes through which materials pass into the lumen in response to suction forces generated by a source of negative pressure coupled to a proximal end of the lumen. A longitudinally-extending vent lumen coupled to a source of at least neutral vent pressure through, for example, an opening to ambient air at the proximal end of the lumen, and preferably, through vent holes disposed along a length of the catheter. A dividing septum between the adjacent lumens has one or more ports fluidically coupling the lumens. The ratio of the area of the suction holes and ports is such that the suction force at unobstructed suction holes is maintained below a desired maximum force for a given negative pressure when none or more of the suctions holes are obstructed. When a suction hole obstruction occurs, fluid is drawn into the suction lumen through the communication port(s). This compensating fluid flow prevents the suction forces from exceeding a predetermined maximum value during use even when one or more suction holes become obstructed. This maximum force may be set, for example, to avoid hematoma, to permit repositioning of the catheter during use, etc. thereby allowing for continuous suction. | 08-25-2011 |