Guarino, US
Andrew Guarino, Newark, DE US
Patent application number | Description | Published |
---|---|---|
20090202481 | Composition for Sustained Release Delivery of Proteins or Peptides - The present invention provides a novel liquid composition suitable for in-situ formation of a depot system to deliver a protein or peptide in a controlled manner. The composition of the present invention comprises: (a) a hydrophobic non-polymeric carrier material; (b) a water miscible biocompatible organic solvent that dissolves the hydrophobic non-polymeric material; (c) a protein or peptide covalently conjugated with one or more formulation performance-enhancing compounds. The present invention also provides a method of manufacturing and use of the composition thereof. | 08-13-2009 |
20100034801 | Non-Polymeric Compositions for Controlled Drug Delivery - The present invention provides a novel liquid composition suitable for in-situ formation of a depot system to deliver a bioactive substance in a controlled manner. The composition of the present invention comprises: (a) a hydrophobic non-polymeric carrier material; (b) a water miscible biocompatible organic solvent that dissolves the hydrophobic non-polymeric material; (c) an ionic complex that is formed between an amphiphilic molecule and a bioactive substance having a net charge at neutral pH in water. The present invention also provides a method of manufacturing and use of the composition thereof. | 02-11-2010 |
Andrew J. Guarino, Newark, DE US
Patent application number | Description | Published |
---|---|---|
20160106804 | Pharmaceutical composition with improved stability - The present invention provides an injectable composition for controlled release drug delivery and the process of making the same, where the composition comprises: a lactate-based polymer having a weight average molecular weight between 5,000 and 50,000 dalton, an acid number of less than 3 mgKOH/g and the content of residual lactide monomers in the lactate-based polymer of less than about 0.3% by weight; a pharmaceutically acceptable organic solvent; and a bioactive substance or a salt thereof that contains an amino acid serine in the molecular structure that is capable of reacting with lactide monomer to form a conjugate; and where the composition reduces the formation of the conjugate. | 04-21-2016 |
Bernard J. Guarino, Bridgewater, NJ US
Patent application number | Description | Published |
---|---|---|
20140310701 | CANCELLING DEVICE OVER THE AIR SOFTWARE UPDATE - A method and system are provided for providing a controlled software update to a group of computing devices. A server distributes a software update over the air to a first group of computing devices, through a wireless communication network. The first group of computing devices is monitored for successful installation of the software update. Upon determining that the software update is subject to a problem or potential problem, a second group of computing devices is identified based on the monitoring of the first group of computing devices. A software update cancellation message is sent through the wireless communication network to the second group of computing devices, instructing the second group of computing devices to cancel the software update in a way that is silent to the user of each respective computing device. | 10-16-2014 |
Bernard J. Guarino, New Hempstead, NY US
Patent application number | Description | Published |
---|---|---|
20100103951 | Adjusting Link Layer Control Frame to Facilitate Data Throughput - A base station subsystem includes logic to change the modulation and coding scheme for radio communications, and logic to communicate with a switching GSM to cause a change in link layer control frame size to reflect the change in modulation and coding scheme. | 04-29-2010 |
20130163459 | Adjusting Link Layer Control Frame to Facilitate Data Thoughput - A base station subsystem includes logic to change the modulation and coding scheme for radio communications, and logic to communicate with a switching GSM to cause a change in link layer control frame size to reflect the change in modulation and coding scheme. | 06-27-2013 |
20140133323 | Adjusting Link Layer Control Frame to Facilitate Data Thoughput - A base station subsystem includes logic to change the modulation and coding scheme for radio communications, and logic to communicate with a switching GSM to cause a change in link layer control frame size to reflect the change in modulation and coding scheme. | 05-15-2014 |
Cassandra Guarino, Slaterville Springs, NY US
Patent application number | Description | Published |
---|---|---|
20110039729 | GLYCOSYLATED PROTEIN EXPRESSION IN PROKARYOTES - The present invention relates to a prokaryotic host cell comprising eukaryotic glycosyltransferase activity, where the eukaryotic glycosyltransferase activity is eukaryotic dolichyl-linked UDP-GlcNAc transferase activity and eukaryotic mannosyl-transferase activity. Also disclosed is a method of producing a glycosylated protein by providing a prokaryotic host cell comprising the eukaryotic glycosyltransferase activity and culturing the prokaryotic host cell under conditions effective to produce a glycosylated protein. Another aspect of the present invention pertains to a method for screening bacteria or bacteriophages by expressing one or more glycans on the surface of a bacteria, attaching a label on the one or more glycans on the surface of the bacteria or on the surface of a bacteriophage derived from the bacteria, and analyzing the label in a high-throughput format. A glycosylated antibody comprising an Fv portion which recognizes and binds to a native antigen and an Fc portion which is glycosylated at a conserved asparagine residue is also disclosed. | 02-17-2011 |
20150232861 | GLYCOSYLATED PROTEIN EXPRESSION IN PROKARYOTES - The present invention relates to a prokaryotic host cell comprising eukaryotic glycosyltransferase activity, where the eukaryotic glycosyltransferase activity is eukaryotic dolichyl-linked UDP-GlcNAc transferase activity and eukaryotic mannosyltransferase activity. Also disclosed is a method of producing a glycosylated protein by providing a prokaryotic host cell comprising the eukaryotic glycosyltransferase activity and culturing the prokaryotic host cell under conditions effective to produce a glycosylated protein. Another aspect of the present invention pertains to a method for screening bacteria or bacteriophages by expressing one or more glycans on the surface of a bacteria, attaching a label on the one or more glycans on the surface of the bacteria or on the surface of a bacteriophage derived from the bacteria, and analyzing the label in a high-throughput format. A glycosylated antibody comprising an Fv portion which recognizes and binds to a native antigen and an Fc portion which is glycosylated at a conserved asparagine residue is also disclosed. | 08-20-2015 |
David R. Guarino, Edwardsburg, MI US
Patent application number | Description | Published |
---|---|---|
20080208509 | System and method for graphically plotting and displaying analyte concentration data on a calendar - A testing device or system is adapted to determine analyte concentrations in a fluid sample and graphically plot the analyte concentrations and display them on a calendar in an easy to read and understand format. | 08-28-2008 |
James C. Guarino, Kalamazoo, MI US
Patent application number | Description | Published |
---|---|---|
20130291583 | TWISTABLE TRAY FOR HEATER LESS ICE MAKER - An ice maker is provided that includes a tray having recesses that can include ice-phobic surfaces. The ice-phobic surfaces may include ice-phobic coatings, textured metal surfaces, hydrophobic coatings or other surfaces configured to repel water and ice. The tray can be formed from metal material and may exhibit a fatigue limit greater than about 150 Megapascals (MPa) at 10 | 11-07-2013 |
James Charles Leslie Guarino, Kalamazoo, MI US
Patent application number | Description | Published |
---|---|---|
20090019870 | VARIABLE POSITION AIR DAMPER FOR A REFRIGERATOR - A refrigerator, including a cabinet having top, bottom, rear and opposing side walls that collectively define a freezer compartment and a fresh food compartment, employs a cooling system and an air plenum to deliver a cooling air flow into the freezer and fresh food compartments. The air plenum includes a variable position air damper having a first, substantially straight portion and a second arcuate portion that forms an air scoop. The air damper is slidably mounted within the air plenum between first and second positions. The variable position air damper is selectively arranged in the first position to efficiently deliver a volume of the cooling air flow into the freezer compartment, the second position to deliver the cooling airflow into the fresh food compartment or in an infinite number of intermediate positions to deliver the cooling airflow into both compartments. | 01-22-2009 |
20110010923 | METHOD OF MAKING AN APPLIANCE DOOR - A method of making an appliance door includes inserting a door pan into a fixture having first and second forming molds. An inner door liner is placed over the door pan. The first and second forming molds are pressed together. A mold cavity is formed between the door pan and the inner door liner. An insulative material is injected into the mold cavity defined by the space between the door pan and the inner door liner. The inner door liner is secured to the door pan to form a base door. A removable decorative exterior skin is extended over the base door. | 01-20-2011 |
20110162393 | VARIABLE POSITION AIR DAMPER FOR A REFRIGERATOR - A refrigerator, including a cabinet having top, bottom, rear and opposing side walls that collectively define a freezer compartment and a fresh food compartment, employs a cooling system and an air plenum to deliver a cooling air flow into the freezer and fresh food compartments. The air plenum includes a variable position air damper having a first, substantially straight portion and a second arcuate portion that forms an air scoop. The air damper is slidably mounted within the air plenum between first and second positions. The variable position air damper is selectively arranged in the first position to efficiently deliver a volume of the cooling air flow into the freezer compartment, the second position to deliver the cooling airflow into the fresh food compartment or in an infinite number of intermediate positions to deliver the cooling airflow into both compartments. | 07-07-2011 |
20120227323 | METHOD OF MAKING AN APPLIANCE DOOR - A method of making an appliance door includes inserting a door pan into a fixture having first and second forming molds. An inner door liner is placed over the door pan. The first and second forming molds are pressed together. A mold cavity is formed between the door pan and the inner door liner. An insulative material is injected into the mold cavity defined by the space between the door pan and the inner door liner. The inner door liner is secured to the door pan to form a base door. A removable decorative exterior skin is extended over the base door. | 09-13-2012 |
James C.l. Guarino, Kalamazoo, MI US
Patent application number | Description | Published |
---|---|---|
20120324913 | ICE MAKING, TRANSFERRING, STORING AND DISPENSING SYSTEM FOR A REFRIGERATOR - An ice making, transferring and storing system includes an icemaker located in the fresh food compartment and an ice storage bin, located in one of the fresh food and freezer compartments, for receiving ice from the icemaker. A first ice transfer mechanism delivers ice from the icemaker to the ice storage bin. An ice dispenser is located in one of the fresh food and freezer doors. A second ice transfer mechanism selectively delivers ice from the ice storage bin to the ice dispenser. | 12-27-2012 |
20140165623 | WEIRLESS ICE TRAY - An ice tray may include a substantially planar body portion with a plurality of cavities that are not interconnected by weirs. The ice tray may include a body having raised portions between adjacent cavities to alleviate stress that may otherwise form in these areas. A water distribution system may be utilized to provide specified volumes of water in the cavities to prevent overflowing of the cavities. | 06-19-2014 |
20150027628 | METHOD OF ENCAPSULATING A PROJECTION AND MAKING AN EVACUATED CABINET - The invention relates to a method of using high velocity metal forming to encapsulate a projection of a non-metallic article by a metallic article and a method of crimping terminal flanges defining an interstitial space therebetween, while trapping a vapor barrier element between the terminal flanges, thereby hermetically sealing the interstitial space. | 01-29-2015 |
20150354871 | AIR CONDITIONER WITH SELECTIVE FILTERING FOR AIR PURIFICATION - A split air conditioner has a cabinet with a fan and evaporator for mounting within a structure. The cabinet includes a filter or a stacked filter system positioned in the flow path between an air inlet and an air outlet for filtering contaminants from the air. Movable dampers are provided for selectively changing the airflow path to selectively bypass the filter to provide a greater or lesser degree of filtration of the air. Preferably, the filter is a high performance HEPA-like filter having substantially less pressure drop . | 12-10-2015 |
20150354872 | AIR CONDITIONER WITH SELECTIVE FILTERING FOR AIR PURIFICATION - A split air conditioner has a cabinet with a fan and evaporator for mounting within a structure. The cabinet includes a filter or a stacked filter system positioned in the flow path between an air inlet and an air outlet for filtering contaminants from the air. Movable filters are provided for selectively bypassing the filters to provide a greater or lesser degree of filtration of the air. Preferably, the filters are high performance HEPA-like filter having substantially less pressure drop . | 12-10-2015 |
20150354874 | AIR CONDITIONER WITH SELECTIVE FILTERING FOR AIR PURIFICATION - A split air conditioner has a cabinet with a fan and evaporator for mounting within a structure. The cabinet includes one or more movable dampers or movable filters positioned in the flow path between the air inlet and the outlet for selectively filtering contaminants from the air to provide a greater or lesser degree of filtration of the air. The movable filters include sliding and/or pivot mounting structure which may accommodate stacking multiple filters with different filtering characteristics. The system may operate in a filtering only mode with no cooling, a cooling only mode with no filtering, or a combination of cooling and selective filtering. | 12-10-2015 |
Joanne Guarino, Milford, CT US
Patent application number | Description | Published |
---|---|---|
20160136462 | WEARABLE ULTRASOUND DEVICE - A wearable ultrasound device and method of using the device includes a power controller with a power source and at least one integrated circuit that delivers electrical power to an applicator. The applicator is electrically coupled to the power controller and a surface of the applicator transmits ultrasound to a wearer for a given duration. The applicator includes radio frequency (RF) drive electronics, an ultrasound transducer coupled to the drive electronics, a monitoring apparatus that includes a thermal cutoff coupled to the drive electronics, where the monitoring apparatus monitors a temperature of the applicator surface and the thermal cutoff turns off the applicator, if the temperature exceeds a pre-defined threshold, and a coupling bandage coupled to the applicator, where the bandage positions the surface of the applicator proximate to a wearer at a location on the body of a wearer. | 05-19-2016 |
Joanne L. Guarino, Slaterville Springs, NY US
Patent application number | Description | Published |
---|---|---|
20130144193 | HYDROGEL ULTRASOUND COUPLING DEVICE - The present invention relates to an ultrasound coupling device that includes a gel component and a coupling compartment. The present invention also relates to various kits and methods for using the ultrasound coupling device with low-intensity ultrasound transducers and therapy. The present invention also relates to methods of making the ultrasound coupling device of the present invention. The present invention further relates to an array that includes a plurality of ultrasound coupling devices of the present invention, and methods of using the array. | 06-06-2013 |
Joseph Guarino US
Patent application number | Description | Published |
---|---|---|
20150360248 | DISPOSABLE ASSEMBLY FOR PREPARING AND WORKING PAINT OR FOR SPRAYING A PRODUCT RESULTING FROM MIXING AT LEAST TWO COMPONENTS, TO BE USED AS A BUCKET ON A SPRAYING TOOL - The disposable assembly has a closed body, for containing a first component and having a lateral surface, a bottom and an upper opening. The bottom has a mounting projection extending within the body for its sealed interlocking engagement in the complementary conformation of the lower end of a hollow inner tubular member intended to contain a second component while its other end is closed by a sealing means. A shutter is tightly mounted on the opening of the body using screws, or by clipping or interlocking. The shutter and the sealing means or the shutter and the hollow tubular element can be a single piece. The presently described embodiments are suitable for producers of paint, varnishes, primers and other products to be sprayed or projected using a gun and other manufacturers of spray or paint guns. | 12-17-2015 |
Joshua Matthew Guarino, Strongsville, OH US
Patent application number | Description | Published |
---|---|---|
20150316079 | CONTROL VALVE AND SYSTEM WITH PRIMARY AND AUXILIARY FUNCTION CONTROL - A method of controlling a hydraulic system having a hydraulic lift function and an auxiliary function includes disabling the hydraulic lift function and the auxiliary function by routing pump flow to tank and opening the lift function and auxiliary function to tank with a single valve; enabling the lift function by closing pump flow to the auxiliary function and routing pump flow to the lift function with the single valve; and enabling the auxiliary function by closing pump flow to the lift function and routing pump flow to the auxiliary function with the single valve. | 11-05-2015 |
20150316171 | HYDRAULIC CONTROL VALVE WITH MANUAL OVERRIDE - A manual override for a hydraulic control valve spool includes a rotatable shaft having a threaded hole; a lever pin having a first end connected for movement with a hydraulic control valve spool and a second end having an external thread that is threadably received in the threaded hole; and the threaded hole and external thread include a mechanical antirotation element. | 11-05-2015 |
Julianne M. Guarino, Edwardsburg, MI US
Patent application number | Description | Published |
---|---|---|
20080208509 | System and method for graphically plotting and displaying analyte concentration data on a calendar - A testing device or system is adapted to determine analyte concentrations in a fluid sample and graphically plot the analyte concentrations and display them on a calendar in an easy to read and understand format. | 08-28-2008 |
20080245692 | Carrying assembly with analyte-determining instrument - A combination of carrying assembly with analyte-determining device. The analyte-determining device includes housing, a display and at least one user-input mechanism. The carrying assembly is adapted to magnetically attach the analyte-determining device. One of the analyte-determining device and the carrying assembly includes at least one magnet. The other of the analyte-determining device and the carrying assembly includes a magnetic-attracting portion. The at least one magnet is attracted to the at least one magnetic-attracting portion and attaches the analyte-determining device and the carrying assembly with each other. | 10-09-2008 |
Julianne M. Guarino, Elkhart, IN US
Patent application number | Description | Published |
---|---|---|
20080268485 | Iconic Display of Markers for a Meter - This invention relates to an iconic display of pre-event or post-event iconic markers for a meter and a method for marking an analyte concentration with a pre-event or post-event iconic marker. The meter includes at least one segment on a display adapted to show a pre-event or post-event iconic marker. The user can interact with the meter via a button on the meter. The button allows the user to scroll from pre-event, post-event, and neither iconic marker, and it also allows the user to select one or neither of the iconic markers. A memory device located within the meter stores the analyte concentration with the corresponding pre-event, post-event, or neither iconic marker. | 10-30-2008 |
Kerry Guarino, Philadelphia, PA US
Patent application number | Description | Published |
---|---|---|
20140051910 | Transport Incubator System Frame with Tank Trays - A transport incubator system includes an incubator, a system frame, and, optionally, supporting components. Supporting components can include a dampening system, slide-out internal compressed gas cylinder storage trays, a monitor mount, handles, strapping points, a chart and hand-held device holder, an electrical control box, a pneumatic control box, an accessory deck, an LED examination light, and a DC distribution component. Methods of using such a transport incubator system are also described. | 02-20-2014 |
Peter Guarino, East Hanover, NJ US
Patent application number | Description | Published |
---|---|---|
20140015197 | BEER PONG GAME AND METHOD OF PLAYING - A game kit comprises, in one embodiment, a plurality of different-sized containers for arranging on a playing surface and for use with a ball for throwing into the containers, and various method for playing the game. | 01-16-2014 |
Richard Guarino, Verona, NJ US
Patent application number | Description | Published |
---|---|---|
20100273844 | PHARMACEUTICAL COMPOSITIONS FOR TREATING OR PREVENTING MIGAINES - The present invention provides a method for treating or preventing one or more types of migraines by administering a monoamine oxidase inhibitor, preferably isocarboxazid, in a rapid-release formulation. The present invention also provides a pharmaceutical composition suitable for treating or preventing migraines and having at least one monoamine oxidase inhibitor. | 10-28-2010 |
Richard A Guarino, Mantaloking, NJ US
Patent application number | Description | Published |
---|---|---|
20160067187 | Methods for Treating or Preventing Migraines - The present invention provides a method for treating or preventing one or more types of migraines by administering a monoamine oxidase inhibitor, preferably Isocarboxazid, to a patient without invoking hypertensive crisis. | 03-10-2016 |
Richard F. Guarino, Fairhaven, MA US
Patent application number | Description | Published |
---|---|---|
20130324776 | PROCESS FOR REDUCING THE BENZENE CONTENT OF GASOLINE - A process is disclosed for alkylating benzene contained in a benzene-containing refinery gasoline stream also comprising at least 0.1 wt % of at least one C6 to C8 olefin. In the process, the refinery gasoline stream is contacted under alkylation conditions with an alkylating agent selected from one or more C2 to C5 olefins in at least a first alkylation reaction zone and a second alkylation reaction zone connected in series to produce an alkylated effluent, which has reduced benzene content as compared with said refinery gasoline stream. All of the refinery gasoline stream is introduced into the first alkylation reaction stage, whereas an aliquot of the alkylated effluent is recycled and introduced to the second, but not the first, alkylation reaction zone. | 12-05-2013 |
20130331626 | PROCESS FOR REDUCING THE BENZENE CONTENT OF GASOLINE - In a process for alkylating benzene contained in a benzene-containing refinery gasoline stream, the benzene-containing refinery gasoline stream is contacted with an alkylating agent selected from one or more C2 to C5 olefins in at least one alkylation reaction zone under alkylation conditions to produce an alkylated effluent which has reduced benzene content as compared with said refinery gasoline stream and is essentially free of said alkylating agent. An aliquot of the alkylated effluent is then recycled to the one at least one alkylation reaction zone such that the molar ratio of alkylatable aromatic compounds to said alkylating agent in the combined refinery gasoline and recycle streams introduced into the at least one alkylation reaction zone is at least 1.0:1. | 12-12-2013 |
20130331627 | PROCESS FOR REDUCING THE BENZENE CONTENT OF GASOLINE BY ALKYLATING BENZENE USING A LOWER OLEFIN IN THE PRESENCE OF A PARAFFINIC DILUENT - A process for reducing the benzene content of gasoline stream, such as a reformate or light naphtha, comprises alkylating the gasoline stream in a reaction zone with an olefin alkylating agent. A paraffinic stream comprising C5 to ClO paraffins is fed to the inlet of the alkylation reaction zone. | 12-12-2013 |
20140194660 | PROCESS FOR REDUCING THE BENZENE CONTENT OF GASOLINE - A process is described for alkylating benzene contained in a refinery gasoline stream, in which the refinery gasoline stream is contacted with an alkylating agent comprising one or more C2 to C5 olefins in an alkylation reaction zone under alkylation conditions to produce an alkylated effluent. The alkylation reaction zone comprises at least a first alkylation reaction stage and a second alkylation reaction stage and a portion of said alkylating agent is fed to each of said first and second alkylation reaction stages so that, although the molar ratio of alkylatable aromatic to alkylating agent in the total feed to the alkylation reaction zone is less than 1, the molar ratio of alkylatable aromatic to alkylating agent at the inlet of each of the first and second alkylation reaction stages is at least 1.0. | 07-10-2014 |
Richard F. Guarino, East Freetown, MA US
Patent application number | Description | Published |
---|---|---|
20100268008 | PRODUCTION OF ALKYL AROMATIC COMPOUNDS - Improved integrated processes for the production of alkyl aromatic compounds are disclosed wherein aromatic compounds which may be treated for removal of deleterious substances are reacted with olefin compounds, which may also be treated for contaminant removal, in the presence of acidic zeolite catalyst(s) to produce the desired alkyl aromatic compound(s). The aromatic and preferably also the olefin feeds are treated substantially to remove contaminants, particularly the nitrogen compounds contained therein, before they are brought together for reaction in the presence of the zeolite catalyst(s). In accordance with the present invention, it has been found that feed pretreatment for removal of nitrogen compounds significantly improves the run length and life of the acidic zeolite catalyst(s). The feed pretreatment of this invention may include the steps of distillation, extraction, and/or adsorption by solid adsorbent, which may be regenerated in accordance with further embodiments of this invention. | 10-21-2010 |
Victor R. Guarino, Pennington, NJ US
Patent application number | Description | Published |
---|---|---|
20140018321 | IMIDAZOLE PRODRUG LXR MODULATORS - Imidazole prodrugs, pharmaceutically acceptable salts, or isomers thereof, of the invention are disclosed, which are useful as modulators of the activity of liver X receptors (LXR). Pharmaceutical compositions containing the compounds and methods of using the compounds are also disclosed. | 01-16-2014 |
20150232491 | PRODRUGS OF 1,4-BENZODIAZEPINONE COMPOUNDS - Disclosed are compounds of Formula (I) and salts thereof, wherein: a) R | 08-20-2015 |
Vito Guarino, Glen Rock, NJ US
Patent application number | Description | Published |
---|---|---|
20130090584 | Joint Decompression Devices - An apparatus for treating a human knee, such as a knee decompression apparatus or device, is described. In some examples, the apparatus includes a bolster, one or more support bars configured to place the bolster proximate to the popliteal fossa of the knee, and one or more straps or other attachment devices configured to removably attach the apparatus to the knee (or, area of the leg that includes the knee) of a patient. | 04-11-2013 |