Ley, US
Andre Ley, Ferndale, MI US
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20110246105 | METHOD AND APPARATUS FOR TESTING AT LEAST ONE TEMPERATURE SENSOR IN A VEHICLE - An apparatus and method for testing a temperature sensor in a vehicle is provided. The apparatus includes a power device. The power device is configured to receive a power signal and to filter the power signal to generate a filtered power signal. The power device is further configured to compare the filtered power signal to a first threshold and to test the temperature sensor based on the comparison of the filtered power signal to the first threshold. | 10-06-2011 |
Arthur C. Ley, Newtown, MA US
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20080274969 | Albumin-Fused Kunitz Domain Peptides - The invention relates to proteins comprising serine protease inhibiting peptides, such as Kunitz domain peptides (including, but not limited to, fragments and variants thereof) fused to albumin, or fragments or variants thereof. These fusion proteins are herein collectively referred to as “albumin fusion proteins of the invention.” These fusion proteins exhibit extended shelf-life and/or extended or therapeutic activity in solution. The invention encompasses therapeutic albumin fusion proteins, compositions, pharmaceutical compositions, formulations and kits. The invention also encompasses nucleic acid molecules and vectors encoding the albumin fusion proteins of the invention, host cells transformed with these nucleic acids and vectors, and methods of making the albumin fusion proteins of the invention using these nucleic acids, vectors, and/or host cells. The invention also relates to compositions and methods for inhibiting neutrophil elastase, kallikrein, and plasmin. The invention further relates to compositions and methods for treating cystic fibrosis and cancer. | 11-06-2008 |
20110092413 | Albumin-Fused Kunitz Domain Peptides - The invention relates to proteins comprising serine protease inhibiting peptides, such as Kunitz domain peptides (including, but not limited to, fragments and variants thereof) fused to albumin, or fragments or variants thereof. These fusion proteins are herein collectively referred to as “albumin fusion proteins of the invention.” These fusion proteins exhibit extended shelf-life and/or extended or therapeutic activity in solution. The invention encompasses therapeutic albumin fusion proteins, compositions, pharmaceutical compositions, formulations and kits. The invention also encompasses nucleic acid molecules and vectors encoding the albumin fusion proteins of the invention, host cells transformed with these nucleic acids and vectors, and methods of making the albumin fusion proteins of the invention using these nucleic acids, vectors, and/or host cells. The invention also relates to compositions and methods for inhibiting neutrophil elastase, kallikrein, and plasmin. The invention further relates to compositions and methods for treating cystic fibrosis and cancer. | 04-21-2011 |
Arthur Charles Ley, Newton, MA US
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20090234101 | DIRECTED EVOLUTION OF NOVEL BINDING PROTEINS - In order to obtain a novel binding protein against a chosen target, DNA molecules, each encoding a protein comprising one of a family of similar potential binding domains and a structural signal calling for the display of the protein on the outer surface of a chosen bacterial cell, bacterial spore or phage (genetic package) are introduced into a genetic package. The protein is expressed and the potential binding domain is displayed on the outer surface of the package. The cells or viruses bearing the binding domains which recognize the target molecule are isolated and amplified. The successful binding domains are then characterized. One or more of these successful binding domains is used as a model for the design of a new family of potential binding domains, and the process is repeated until a novel binding domain having a desired affinity for the target molecule is obtained. In one embodiment, the first family of potential binding domains is related to bovine pancreatic trypsin inhibitor, the genetic package is M13 phage, and the protein includes the outer surface transport signal of the M13 gene III protein. | 09-17-2009 |
Brian Robert Ley, Washington, MO US
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20110031088 | Clutch Brake - A clutch brake for use in association with a braking mechanism for braking rotation of a shaft connecting an engine to a transmission. The clutch brake includes first and second clutch brake sections having first and second lock plates. The first and second clutch brake sections are selectively configurable in a disconnected configuration and a connected configuration. The clutch brake further comprises a fastening mechanism on the first and second lock plates for fastening the first and second clutch brake sections in the connected configuration. The fastening mechanism includes a first fastening component on the first lock plate and a second fastening component on the second lock plate. The first fastening component further includes a fastener body movably mounted in an opening in the first lock plate, and a fastening arm extending from the fastener body. The fastener body is movable from a fastening position, to a release position. | 02-10-2011 |
20110226579 | CENTRIFUGALLY ASSISTED CLUTCH - A friction clutch assembly connects driving and driven shafts and has a pressure plate axially moveable between an engaged position transmitting torque from the driving shaft to the driven shaft and a disengaged position. The assembly includes levers and a plurality of centrifugal-assist weights on the levers adjacent outer ends of the levers. The centrifugal-assist weights are arranged to apply an increased force urging the pressure plate to its engaged position upon rotation of the cover and the levers. The centrifugal-assist weights are suitably configured to provided the desired amount of increased force. | 09-22-2011 |
20150083544 | SELF-ADJUSTING MECHANISM FOR A FRICTION CLUTCH - A self-adjusting mechanism for a friction clutch is disclosed. The mechanism includes first and second hub members with mating ratchet teeth, and an adjustment arm having a non-slip connection with the first hub member for driving the first hub member in opposite rotational directions, and a worm gear which, when rotated, moves an adjustment ring of the clutch to adjust the friction surfaces to compensate for wear. The mechanism also includes a lost-motion connection located between the worm gear and the release mechanism of the clutch. The adjustment arm on the first hub member has a connection with the release mechanism of the clutch. The release mechanism is movable through an adjustment cycle during which the worm gear is rotated to move the adjustment ring of the clutch to adjust friction surfaces to compensate for wear. | 03-26-2015 |
Bruce Ley, Ossian, IN US
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20140265984 | System For Selecting An Output Speed For An Electric Motor - An electric motor has a control circuit that enables an operational speed of the electric motor to be selected with reference to multiple ranges of speeds and the input voltage to the motor. Switching between speed ranges occurs in response to activation of a switch or in response to expiration of a time period set by a selector switch. | 09-18-2014 |
20140271280 | PUMP MOTOR - An electric pump motor is provided. The motor includes a stator assembly including a magnetic stator component and an overmolded stator casing sealingly encapsulating the magnetic stator component. A rotor assembly that is rotatable about an axis includes a rotor shaft extending along the axis, a magnetic rotor component, and an overmolded rotor casing fixedly interconnecting the rotor shaft and magnetic rotor component. The rotor shaft is connected to an impeller that imparts a thrust load on the rotor shaft. The rotor and stator assemblies are configured so that the magnetic components induce a solenoid force on the rotor shaft opposite the thrust load. | 09-18-2014 |
Bruce Calvin Ley, Ossian, IN US
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20080295543 | WASHING MACHINE APPARATUS AND METHOD - A washing machine is provided that includes an induction motor and a motor control circuit with a feedback loop. The feedback loop provides rotor speed to a microprocessor of the motor control circuit. The motor control circuit and feedback loop control the motor such that the motor operates in a reverse frequency mode which provides braking to the washing machine. | 12-04-2008 |
20080297011 | INTEGRATED CONTROLLER/MOTOR WITH THERMAL OVERLOAD SENSOR - An integrated controller/motor energized by a power supply includes a controller that has controller circuits and a pair of controller lead lines connectable in circuit between the power supply and the controller circuits. The integrated controller/motor also includes a motor that has a first motor winding and a second motor winding each in circuit with the controller circuits and a thermal overload sensor located in direct proximity to the first motor winding and the second motor winding. The thermal overload sensor may be connected in series with at least one of the controller lead lines. A method of protecting an integrated controller/motor from thermal overload is also presented. | 12-04-2008 |
20080297098 | WASHING MACHINE APPARATUS AND METHOD - A washing machine is provided that includes an induction motor and a motor control circuit with a feedback loop. The feedback loop provides rotor speed to a microprocessor of the motor control circuit. The motor control circuit and feedback loop control the motor such that the motor operates in a negative slip mode which provides braking to the washing machine. | 12-04-2008 |
20080297275 | DUAL CONFIGURATION FILTER CIRCUIT - A low current leakage circuit for power source lines that include a first power line at one potential and a second power line at another potential with respect to the first power line and that carry energy to power a device is provided. The low leakage circuit may include a filter circuit connected in parallel with the device and between the first power line and the second power line. The filter circuit may have a junction in circuit with a local ground and a switch may be connected in series between the junction and the local ground. A method of reducing current leakage in a filter circuit for power source lines carrying energy for powering a device is also provided. | 12-04-2008 |
20090160276 | MOTOR ASSEMBLY - A motor includes a rotor core and a stator core disposed about the rotor core. The stator core includes three support portions and at least one end bracket supporting the stator core solely by three mounting portions that are interconnected with a respective support portion. A method of mounting an end shield to a laminated motor stator core is also presented. | 06-25-2009 |
20100107498 | GARAGE DOOR OPENER - This invention relates generally to a garage door opener. The garage door opener has a user interface and a motor operatively connected to the garage door, at least one sensor, and an integrated motor control circuit. The integrated motor control circuit has a motor control microprocessor and a memory. The memory contains previous operation data. The motor control microprocessor receives data from the user interface, the memory and the sensors to control the motor. | 05-06-2010 |
Cary M. Ley, Andover, MN US
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20140352735 | ZERO LAG DISPENSE APPARATUS - A wafer cleaning method includes dispensing liquid chemicals at two flow rates to start a chemical reaction, with the second flow rate being lower than the first. The method also includes dispensing liquid waters at two flow rates to stop a chemical reaction, with the second flow rate being lower than the first. | 12-04-2014 |
20140352738 | ZERO LAG DISPENSE APPARATUS - A liquid dispenser for a wafer processing system includes a supply tube with an inlet at one end and an outlet at the other end. Attached to the supply tube at the outlet end is a liquid reservoir. The liquid reservoir has a dispensing plate that has an outlet for dispensing liquid onto a wafer. There is also a dispensing valve for controlling the dispensing of the liquid. | 12-04-2014 |
20160086811 | VERTICAL NO-SPIN PROCESS CHAMBER - A processing chamber includes a base, a cover, and grippers. The base includes a body, a mating surface, an inner zone cavity extending into the body, a divider substantially surrounding the inner zone cavity, and an outer zone cavity extending into the body and substantially surrounding the divider. The cover includes a mating surface that contacts the body mating surface when the processing chamber is closed. The grippers hold the wafer in the inner zone cavity when the processing chamber is closed. | 03-24-2016 |
David J. Ley, Plantation, FL US
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20150256535 | METHODS AND SYSTEMS FOR TOKEN-BASED APPLICATION MANAGEMENT - Disclosed herein are methods and systems for token-based application management. In an embodiment, requests are received from applications for tokens that can be active or inactive. A token-interaction-directive pool is maintained in data storage, each directive having a triggering token, a target token, and one or both of triggering-token actions and target-token actions. Responsive to receiving a token request from an application, any directives having their triggering token equal the requested token and having their target token active are identified. A response plan that includes the actions in the identified directives is generated. Any triggering-token actions in the response plan are communicated to the requesting application, and any target-token actions in the response plan are communicated to each application that is authorized to access the corresponding target token. | 09-10-2015 |
20150271649 | METHOD AND APPARATUS FOR A BACK CHANNEL IN A HALF-DUPLEX COMMUNICATION SYSTEM - A method and apparatus for a back channel implemented by a transmitting device in a half-duplex communication system includes monitoring for voice activity detection, indicative of an absence of human speech, while the transmitting device is transmitting on a half-duplex channel of the half-duplex communication system; transmitting a notification of a back channel opportunity to other devices on the half-duplex channel responsive to the voice activity detection; and switching to a receiving mode to receive data on the back channel while still maintaining control of the half-duplex channel. A method for a back channel implemented by a receiving device is also described. | 09-24-2015 |
Geoffrey Thomas Ley, Dallas, TX US
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20110052777 | Method for Making a Rolled Snack Food Product Having a Light Crispy Texture - A method for making a cooked rolled snack food from a starch based dough. The starch based dough is admixed with a small average particle size monoglyceride. The dough is then rolled and cooked in hot oil. The fatty acid chain is disposed within the helical amylose molecules in the starch-based dough and provides structural support within the helix. This support helps control inward expansion of the rolled dough snack during frying. | 03-03-2011 |
Gregory R. Ley, New Brighton, MN US
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20080262587 | EXTENDABLE AND RETRACTABLE LEAD HAVING A SNAP-FIT TERMINAL CONNECTOR - A lead having an extendable and retractable fixation mechanism has a rotating terminal pin at the terminal end which rotates the fixation mechanism at the distal end. As the terminal pin is rotated, the fixation mechanism is extended or retracted from the distal end of the lead. A threaded collar allows for the fixation mechanism to smoothly extend and retract from the lead, and allows for a 1:1 turn ratio between the terminal pin and the fixation mechanism. A fluoroscopic ring disposed at the distal end of the lead provides information during the implantation process. | 10-23-2008 |
Herbert F. Ley, Wellsboro, PA US
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20110249335 | LENS COVERING AND CLEANING APPARATUS - An apparatus including a cap adapted for covering, protecting and cleaning a lens of a device such as a scope of a firearm. The cap may be manipulated to clean the lens, such that when the cap is opened, the lens is clean, with the scope ready for use. | 10-13-2011 |
Jason Ley, Detroit, MI US
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20150119153 | Propshaft Assembly With Damper - A propshaft assembly that includes a tubular member, first and second end connections coupled to opposite ends of the tubular member and a damper that is received in the tubular member and positioned between the first and second end connections. The tubular member has a wall member that defines an interior circumferential surface. The damper has a first damping device, a second damping device and a third damping device. The first damping device has a first core and a first damping member that is fixed to the first core. The first damping member extends helically about the first core and engages the interior circumferential surface. The second damping device is formed of foam and is positioned in the tubular member between the first and third damping devices. The second damping device engages the interior circumferential surface. The third damping device has a second core and a second damping member that is fixed to the second core. The second damping member extends helically about the second core and engages the interior circumferential surface. | 04-30-2015 |
20150300449 | DAMPED PROPSHAFT ASSEMBLY AND METHOD FOR FABRICATING A DAMPED PROPSHAFT ASSEMBLY - A damped propshaft assembly with a hollow shaft and a tuned damper, which is received in the hollow shaft and includes a liner and a damping member. The liner's mass and stiffness are tuned to attenuate one or more of a bending mode vibration and a torsion mode vibration that occurs at a first predetermined frequency. The liner is not configured to substantially damp shell mode vibration that occurs at a frequency that is not equal to the first predetermined frequency. The damping member is coupled to the liner and is configured to primarily attenuate shell mode vibration in the hollow shaft at one or more desired frequencies. The tuned damper attenuates the at least one of the bending moment vibration and the torsion mode vibration at the first predetermined frequency and also attenuates shell mode vibration. A method for forming a damped propshaft assembly is also provided. | 10-22-2015 |
Jason Ley, Rochester Hills, MI US
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20160047436 | DAMPED PROPSHAFT ASSEMBLY AND TUNED DAMPER FOR A DAMPED PROPSHAFT ASSEMBLY - A damped propshaft assembly with a hollow shaft and a tuned damper, which is received in the hollow shaft and includes a liner and a damping member. The liner's mass and stiffness are tuned to attenuate one or more of a bending mode vibration and a torsion mode vibration that occurs at a first predetermined frequency. The liner is not configured to substantially damp shell mode vibration that occurs at a frequency that is not equal to the first predetermined frequency. The damping member is coupled to the liner and is configured to primarily attenuate shell mode vibration in the hollow shaft at one or more desired frequencies. The tuned damper attenuates the at least one of the bending moment vibration and the torsion mode vibration at the first predetermined frequency and also attenuates shell mode vibration. A method for forming a damped propshaft assembly is also provided. | 02-18-2016 |
Jeff Ley, Cranberry, PA US
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20150204191 | FLUID TANK BALANCING SYSTEM FOR MINING MACHINE - A mining machine includes a frame, a first fluid tank, a second fluid tank, a valve, and a control system. The first fluid tank is supported on the frame proximate a first end, and the second fluid tank is supported on the frame proximate a second end. The valve permits fluid communication between the first and second fluid tanks when the valve is in a first position, and prevents fluid communication between the first and second fluid tanks when the valve is in a second position. The control system includes a first sensor detecting an amount of fluid in the first tank, a second sensor detecting an amount of fluid in the second tank, and a controller. The controller moves the valve to the first position when the difference between the amounts of fluid in the first and second tanks a predetermined threshold. | 07-23-2015 |
Jeffrey A. Ley, Cranberry, PA US
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20160061031 | PAN PITCH CONTROL IN A LONGWALL SHEARING SYSTEM - A system and corresponding method of monitoring a longwall shearing mining machine in a longwall mining system, where the shearing mining machine includes a shearer having a cutter drum, the method includes obtaining, by a processor, desired pitch angle information, and receiving, by the processor, a pitch angle indicative of a current pitch position of the shearer. The method also includes determining, by the processor, whether the pitch angle is within a desired pitch angle range, and controlling, by the processor, a position of the cutter drum based on whether the pitch angle is within the desired pitch angle range. The desired pitch angle range is based on the desired pitch angle information. | 03-03-2016 |
John Ley, Oregon, IL US
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20140035786 | PATCH ANTENNA - A patch antenna comprises a patch radiator, at least a first connection point for at least a first radio frequency signal, and at least a first feed structure. The first feed structure is arranged to connect the first connection point to at least two feed points on the patch radiator, a first of the feed points being disposed adjacent to a first edge of the patch radiator, and a second of the feed points being disposed adjacent to a second edge of the patch radiator, the first and second edges being on opposed sides of a central region of the patch radiator. The first feed structure comprises at least a first transmission line arranged to connect the first of the feed points to the second of the feed points, the transmission line being disposed in a substantially parallel relationship to the patch radiator. | 02-06-2014 |
John F. Ley, Oregon, IL US
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20140118220 | REFLECTOR ARRANGEMENT FOR ATTACHMENT TO A WIRELESS COMMUNICATIONS TERMINAL - A reflector arrangement is configured for attachment to a wireless communications terminal having a patch antenna. The patch antenna includes a patch radiator in a substantially parallel relationship with a ground plane, and the patch antenna produces a radiation beam of a predetermined beamwidth. The reflector arrangement is configured, when attached to the terminal, to produce a radiation beam of reduced beamwidth relative to the predetermined beamwidth. The reflector arrangement comprises a main reflector and a sub-reflector for reflecting radiation towards the main reflector, and the reflector arrangement is configured such that, when attached to the terminal, the patch antenna acts as a feed antenna for the sub-reflector. The sub-reflector is arranged to collect the radiation from the patch antenna and to reflect the beam towards the main reflector such that the main reflector produces the radiated beam of reduced beamwidth. | 05-01-2014 |
20150215013 | METHOD AND APPARATUS FOR A MULTI-USER MULTIPLE INPUT MULTIPLE OUTPUT (MU-MIMO) NETWORK WITH SINGLE TRANSCEIVER SUBSCRIBER MODULES - In a multi-user multiple input multiple output (MU-MIMO) wireless network comprising an access point and several subscriber modules, a subscriber module configured with a single transceiver and two antennas elements operates a polarization switch to cause one of the two antenna elements to be connected with the single transceiver. The polarization switch may be operated in response to receiving a command from the access point. A scheduler in the access point is configured to send the command to cause the subscriber module to operate the polarization switch. | 07-30-2015 |
John Francis Ley, Oregon, IL US
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20160104943 | PATCH ANTENNA-BASED WIDEBAND ANTENNA SYSTEM - Devices describe herein are configured to radiate radio frequency (RF) energy corresponding to RF signals from a first range of frequencies. The device comprises a patch antenna assembly comprising a microstrip disposed on a printed circuit board and a patch antenna. The device also includes a transmitter configured to generate RF signals from the first range of frequencies at an output of the transmitter and a center feed assembly comprising a waveguide, a lens and the patch antenna assembly disposed in the waveguide. The center feed assembly is configured to radiate from the lens radio frequency (RF) energy corresponding to RF signals from first range of frequencies at a power level greater than the first power level. | 04-14-2016 |
Joseph W. Ley, Tucson, AZ US
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20110287541 | ACCORDION BIOREACTOR - Disclosed herein are bioreactors including a first sheet and a second sheet (one or both of which is substantially transparent to light), wherein the second sheet is disposed adjacent to the first sheet, and the first and second sheets are sealed along a first longitudinal edge, a second longitudinal edge, a first horizontal edge, a second horizontal edge, and at least one intermediate horizontal seal between the first horizontal edge and the second horizontal edge, thereby forming at least two chambers for holding fluid in series along a vertical axis, wherein each of the two or more chambers is oriented at an angle relative to the vertical axis, wherein the angle is about 0° to about 90° and at least one of the chambers is oriented at an angle greater than 0°, and wherein there is at least one opening in each of the first horizontal edge, the second horizontal edge, and intermediate horizontal seal(s); a support structure comprising at least one horizontal support, wherein the horizontal support is located at or near the position of the intermediate horizontal seal; a reservoir below the second horizontal edge of the first and second sheets; and a means for pumping fluid from the reservoir to the first horizontal edge of the first and second sheets. Also disclosed are methods of culturing cells including circulating a suspension of cells in a disclosed bioreactor. In some examples, the cells include microalgae, macroalgae, bacteria, fungi, insect cells, plant cells, animal cells (such as mammalian cells), or plant or animals tissue or organs. In particular examples, the method includes exposing the culture in the bioreactor to a light source (such as sunlight or an artificial light source). | 11-24-2011 |
Josh Ley, Erie, CO US
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20080278020 | STATOR FOR PERMANENT MAGNET ELECTRIC MOTOR USING SOFT MAGNETIC COMPOSITES - A stator of an electrical machine operable as a motor or a generator, applicable to a radial-axial type machine. The stator includes a plurality of stator segments disposed circumferentially about an axis. Each segment has a generally wedge shaped core and a winding wound around the core. The winding is bent to have portions that are disposed on multiple planes. The core includes an elongated wedge tip portions aligned parallel to the axis and an outer radial face opposite to the tip portion. The multiple planes include at least one plane substantially normal to the axis and at least one plane tangential to the radial face. | 11-13-2008 |
20080278021 | Stress Distributing Permanent Magnet Rotor Geometry For Electric Machines - A rotor includes a cylindrical rotor core having an outer circumferential surface and a plurality of magnet insertion holes formed in the rotor core and arranged circumferentially at a preset angular interval about the rotational axis of the rotor core. Each hole extends in a direction parallel to the rotational axis and has a cross section of a generally elongated slit. The elongated slit is curved concave relative to the circumferential surface and has a radially inward side, a radially outward side, and two ends that are respectively spaced apart from the circumferential surface by two bridges, wherein each bridge has thinner and thicker portions that are respectively positioned near the radially inward and outward sides. One or more permanent magnets are inserted in each hole and arranged to transfer centrifugal forces acting on the magnets during operation to portions of the bridges. | 11-13-2008 |
20110121677 | ROTOR FOR A PERMANENT MAGNET ELECTRIC MACHINE - A rotor for a permanent magnet electric motor includes a rotor core having a generally cylindrical shape with an outer circumferential surface and a rotational axis and a plurality of magnet insertion hole arrangements formed in the rotor core and arranged circumferentially at a preset angular interval about the rotational axis. Each hole arrangement has a radially inward side, a radially outward side, and two ends that are respectively spaced apart from the circumferential surface by respective bridge regions formed by the rotor core. The material of the bridge regions is metallurgically transformed by having its grain structure changed, e.g., by heating the material to at least its Curie temperature, whereby the material possesses greater magnetic reluctance than the material of adjacent portions of the rotor core. | 05-26-2011 |
20120217834 | BRUSHLESS PM MACHINE CONSTRUCTION ENABLING LOW COERCIVITY MAGNETS - The present disclosure provides a brushless permanent magnet machine which includes an essentially circular shaped rotor, and a pair of magnets arranged in the rotor. The magnets are each U-shaped and have a thickness direction extending along a contour of the corresponding magnet between the opposite poles of the corresponding magnet, respectively. The magnets are each composed of a non-rare earth material having a lower coercivity than a rare earth material. A direction of magnetization of each of the pair of magnets is parallel to the thickness direction of the corresponding magnet. The present disclosure also provides a method of manufacturing such a brushless permanent magnet machine. | 08-30-2012 |
Kenneth D. Ley, Cotopaxi, CO US
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20140251831 | LEAK DETECTION FORMULA, ANALYZER and METHODS OF USE - Detecting a leak from a site in a sealed system with a source of pressurized gas which is capable of passing through the site, a composition of matter which adheres to the surfaces of the system and which is capable of showing the presence of the gas escaping from the site. The method includes: injecting gas into the system to a pressure in excess of the surrounding pressure, and covering the external surface with the composition to identify the location of the site by the interaction of the escaping gas with the composition. The composition is foam that includes a surfactant which forms a least one bubble in the presence of escaping gas and an indicator which changes color in the presence of the escaping gas. The leak is an opening down to at least the size of a hole 0.001″ in diameter. A gas detector may also be used. | 09-11-2014 |
Kevin Ley, Santa Fe, NM US
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20080213747 | FLUORESCENT POLYMER SUPERQUENCHING-BASED BIOASSAYS - A chemical composition including a fluorescent polymer and a receptor that is specific for both a target biological agent and a chemical moiety including (a) a recognition element, (b) a tethering element, and (c) a property-altering element is disclosed. Both the fluorescent polymer and the receptor are co-located on a support. When the chemical moiety is bound to the receptor, the property-altering element is sufficiently close to the fluorescent polymer to alter the fluorescence emitted by the polymer. When an analyte sample is introduced, the target biological agent, if present, binds to the receptor, thereby displacing the chemical moiety from the receptor, resulting in an increase of detected fluorescence. Assays for detecting the presence of a target biological agent are also disclosed. | 09-04-2008 |
Kevin R. Ley, Elk River, MN US
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20080234744 | SPINAL STABILIZATION SYSTEM WITH RIGID AND FLEXIBLE ELEMENTS - A spinal stabilization system generally comprises first and second anchor members configured to be secured to first and second vertebrae within a patient's body, a flexible element secured to the first anchor member, and a rigid element secured to the second anchor member. An end portion of the rigid element is coupled to an end portion of the flexible so that the system is able to provide both rigid and dynamic stabilization. The coupling is maintained even if the flexible element relaxes after a period of time within the patient's body. | 09-25-2008 |
20120016421 | SPINAL STABILIZATION SYSTEM WITH RIGID AND FLEXIBLE ELEMENTS - A spinal stabilization system generally comprises first and second anchor members configured to be secured to first and second vertebrae within a patient's body, a flexible element secured to the first anchor member, and a rigid element secured to the second anchor member. An end portion of the rigid element is coupled to an end portion of the flexible so that the system is able to provide both rigid and dynamic stabilization. The coupling is maintained even if the flexible element relaxes after a period of time within the patient's body. | 01-19-2012 |
20150230827 | SPINAL STABILIZATION SYSTEM WITH RIGID AND FLEXIBLE ELEMENTS - A spinal stabilization system generally comprises first and second anchor members configured to be secured to first and second vertebrae within a patient's body, a flexible element secured to the first anchor member, and a rigid element secured to the second anchor member. An end portion of the rigid element is coupled to an end portion of the flexible so that the system is able to provide both rigid and dynamic stabilization. The coupling is maintained even if the flexible element relaxes after a period of time within the patient's body. | 08-20-2015 |
Klaus Ley, La Jolla, CA US
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20120121590 | METHODS OF INHIBITING ADVERSE CARDIAC EVENTS AND TREATING ATHEROSCLEROSIS AND CORONARY ARTERY DISEASE USING GALECTIN-3 BINDING PROTEIN (GAL-3BP, BTBD17B, MAC-2 BINDING PROTEIN) - The invention provides Galectin-3 binding protein (Gal-3BP, BTBD17B) polypeptide sequences and compositions that include Gal-3BP polypeptide sequences, and methods of using Gal-3BP polypeptide sequences, including modified forms and wild type (native) forms of Gal-3BP polypeptide, such as in treatment, diagnostic, detection and prognostic methods. | 05-17-2012 |
20130095127 | METHODS OF INHIBITING INFLAMMATION AND INFLAMMATORY DISEASES USING Gal-3BP (BTBD17B, LGALS3BP, GALECTIN-3 BINDING PROTEIN, MAC-2 BINDING PROTEIN) - The invention provides Galectin-3 binding protein (Gal-3BP, BTBD17B) polypeptides, Gal-3BP compositions, and methods of use, and uses, for example, in treatment, diagnostic, detection and prognostic methods, such as treatment of an undesirable or aberrant immune response, immune disorder, inflammatory response, or inflammation, and treatment of an autoimmune response, disorder or disease. | 04-18-2013 |
20130108602 | METHODS AND USES OF NUR77 AND NUR77 AGONISTS TO MODULATE MACROPHAGES AND MONOCYTES, AND TREAT INFLAMMATION, INFLAMMATORY DISEASE AND CARDIOVASCULAR DISEASE | 05-02-2013 |
20150119333 | METHODS OF INHIBITING ADVERSE CARDIAC EVENTS AND TREATING ATHEROSCLEROSIS AND CORONARY ARTERY DISEASE USING GALECTIN-3 BINDING PROTEIN (GAL-3BP, BTBD17B, MAC-2 BINDING PROTEIN) - The invention provides Galectin-3 binding protein (Gal-3BP, BTBD17B) polypeptide sequences and compositions that include Gal-3BP polypeptide sequences, and methods of using Gal-3BP polypeptide sequences, including modified forms and wild type (native) forms of Gal-3BP polypeptide, such as in treatment, diagnostic, detection and prognostic methods. | 04-30-2015 |
Klaus F. Ley, La Jolla, CA US
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20090022712 | Compositions and Methods for Inhibiting Leukocyte Function - The present invention provides compositions and methods for regulating leukocyte migration and function. The present invention also provides compositions and methods for preventing and inhibiting lung injury and damage associated with neutrophil infiltration of the lung. | 01-22-2009 |
20090093005 | PROTEIN-BASED BIOMARKERS FOR ABDOMINAL AORTIC ANEURYSM - The present invention encompasses compositions and methods useful for diagnosing subjects with abdominal aortic aneurysms. The invention relates to the use of protein biomarkers whose levels are different in subjects with abdominal aortic aneurysms relative to normal subjects. | 04-09-2009 |
20100055723 | Galectin-3-Binding Protein as a Biomarker of Cardiovascular Disease - The present invention provides compositions and methods for using biomarkers to diagnose and monitor cardiovascular associated diseases and disorders. More specifically, the present invention provides Galectin-3-binding protein as a biomarker for disease. | 03-04-2010 |
Matthew Tyler Ley, Stillwater, OK US
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20140096593 | SYSTEM AND METHOD FOR RAPID MEASUREMENT OF THE AIR VOID DISTRIBUTION OF FRESH CONCRETE - According to an embodiment, there is provided herein a method of determining the air void distribution in a sample of fresh concrete. One embodiment of the invention determines a parameter related to air void distribution by applying a known pressure to a fresh concrete sample, measuring a first value representative of the volume under compression, releases at least a portion of the pressure, reapplies the same pressure to the sample, measures a second value representative of the volume under the second compression, and uses differential between the first and second values to estimate a parameter related to the air void distribution. | 04-10-2014 |
20140173903 | Prefabricated Structural Concrete Beam and Methods for Use - A structural beam, and methods for use, comprising a prefabricated structural concrete portion and a poured-in-place structural concrete portion, wherein said poured-in-place portion comprises at least ten percent of the total weight of said structural beam. Reinforcing extends from the prefabricated portion to the poured-in-place portion. In a preferred embodiment, the structural beam is an “inverted-T” beam, and the prefabricated structural concrete portion comprises the lower corbel portion of the beam, and the poured-in-place portion comprises an upper stem portion of the beam. | 06-26-2014 |
20150030777 | CONCRETE CURING PRODUCT AND METHOD OF USE - A mixture includes a pulped solid material, water, a viscosity modifier, and a dye. The solid material, water, viscosity modifier, and dye are mixed to form a slurry that will adhere in a layer onto a freshly finished concrete structure for purposed of aiding in curing the concrete. | 01-29-2015 |
Michael Scott Ley, Moon Township, PA US
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20090204538 | USER INTERFACE AND SYSTEM INCLUDING SAME - A graphical user interface including a controller for redistributing funds between a first account and a second account. The controller includes a slidable element positionable over a fixed background element to define a first segment and a second segment of the background element. A length of the first segment is representative of a balance of the first account, and a length of the second segment is representative of a balance of the second account. | 08-13-2009 |
M. Tyler Ley, Stillwater, OK US
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20120007579 | EMBEDDED WIRELESS CORROSION SENSOR - A corrosion sensor is disclosed. The corrosion sensor has a retainer and a microcontroller retained by the retainer. A length of antenna wire arranged in a wound configuration is retained by the retainer and connected to the microcontroller. A corrosion sensitive element is conductively connected to the microcontroller. The microcontroller is programmed to receive a power signal from the antenna wire and test for corrosion of the corrosion sensitive element. The he microcontroller is also programmed to transmit a signal indicative of the test results via the antenna. | 01-12-2012 |
Ruth E. Ley, St. Louis, MO US
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20100172874 | GUT MICROBIOME AS A BIOMARKER AND THERAPEUTIC TARGET FOR TREATING OBESITY OR AN OBESITY RELATED DISORDER - The present invention relates to the gut microbiome as a biomarker and therapeutic target for energy harvesting, weight loss or gain, and/or obesity in a subject. In particular, the invention provides methods of altering and monitoring the relative abundance of | 07-08-2010 |
20140093478 | GUT MICROBIOME AS A BIOMARKER AND THERAPEUTIC TARGET FOR TREATING OBESITY OR AN OBESITY RELATED DISORDER - The present invention relates to the gut microbiome as a biomarker and therapeutic target for energy harvesting, weight loss or gain, and/or obesity in a subject. In particular, the invention provides methods of altering and monitoring the relative abundance of | 04-03-2014 |
Ruth E. Ley, Ithaca, NY US
Patent application number | Description | Published |
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20150050293 | FLAGELLUM AND ANTI-FLAGELLUM ANTIBODY LEVELS IN SAMPLES AS A DIAGNOSTIC BIOMARKER AND THERAPEUTIC TARGET FOR METABOLIC SYNDROME - High levels of bacterial flagella in a sample such as a gastrointestinal sample and/or low levels of anti-flagella antibodies serve as an indication for metabolic syndrome (such as insulin resistance, hypertension, elevated cholesterol, increased risk for blood clotting, and obesity) with highest levels of adiposity. An intervention that reduces the level and/or activity of flagella in the gastrointestinal tract can mitigate the severity of metabolic syndrome or in protecting against the development of metabolic syndrome. | 02-19-2015 |
Ryan M. Ley, Wilmington, NC US
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20150143734 | Artificial Gun Mounting Accessory - An improved artificial accessory device for mounting on to a gun rail integration system of a weapon having a weighted housing, a thumb screw positioned on a bottom portion of the improved light structure, a threaded hole through which the thumb screw passes through into a small platform, a recoil groove for receiving gun recoil, a track for receiving the gun recoil and a pair of track extending members designed to allow gun trigger housing to fit in between. The thumb screw is designed to be tightened to engage the improved artificial accessory device with a bottom portion of the gun recoil. Specifically, the thumb screw when turned drives a small platform, that can be spring loaded and featuring a raised ridge, upward into a position flush with the bottom of the gun recoil and fitting the ridge within a counterpart recess in the bottom of the gun recoil. | 05-28-2015 |
Thomas A. Ley, La Crosse, WI US
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20110064571 | Secondary Inlet Cone for a Plenum Fan - A plenum fan comprising a fan wheel disposed within a box-like enclosure includes a secondary inlet cone, a primary inlet cone, and a flexible duct. The two inlet cones convey air to the mouth of the fan wheel. A frame supports the fan wheel and the primary inlet cone such that the frame, the fan wheel and the primary inlet cone comprise a fan assembly. If the fan assembly shifts due to fan thrust or vibration, the fan assembly moves as a unit. The flexible duct connects the primary inlet cone to an inlet of the enclosure while isolating the fan assembly's vibration from the enclosure. The secondary inlet cone extends from the inlet of the enclosure, protrudes into or toward the primary inlet cone and provides a smooth airflow path over the abrupt shape of the flexible duct. | 03-17-2011 |
20150040601 | ANTI-MICROBIAL HEAT TRANSFER APPARATUS - An anti-microbial heat transfer apparatus comprises a hybrid coil with multiple rows of fins and tubes. The fins and tubes have an upper portion and a lower portion. The upper portion comprises fins that include copper and has a height that is different than the height of the second portion. A chilled medium inside the tubes makes the surface of the fins and tubes colder than the temperature of the dew point of the surrounding air such that a condensate is formed on the surface of the fins. Gravity causes the condensate to drip copper ions from the upper portion to the lower portion of the coil resulting in the inhibition of microbial growth on the coil. | 02-12-2015 |
Timothy J. Ley, Shoreview, MN US
Patent application number | Description | Published |
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20080319531 | FLEXIBLE AND EXPANDABLE STENT - In one embodiment of the invention, a stent may be provided comprising a first undulating band having alternating peaks and troughs, a second undulating band having alternating peaks and troughs, a first substantially longitudinal connector extending between the first and second undulating bands and a second very short connector extending between the first and second undulating bands, the first connector substantially longer than the second very short connector. | 12-25-2008 |
20100131047 | Stent Cell Configurations - A generally cylindrical, radially expandable stent may be composed of a plurality of interconnected multibonate cell structures. The cells have three or more enlarged end portions radiating from a common center within the cell. The cells may be of tribonate or higher order multibonate configuration. Stents composed up of a series of generally multibonate cell elements are also disclosed. | 05-27-2010 |
20100132718 | Occlusion Stent - A device for occluding a target body lumen, comprises a wire structure defining a wire structure lumen extending therethrough and movable between a reduced diameter insertion configuration and an expanded diameter deployed configuration and a basket structure extending across the wire structure lumen and including therein a cell growth promoting agent to promote cell growth across the wire structure lumen to occlude the target body lumen. | 06-03-2010 |
20110282435 | Longitudinally Flexible Expandable Stent - Segmented articulatable stent of open structure comprised of end-connected struts of first and second lengths making up first and second segments with angular interconnects between adjacent first and second segments. | 11-17-2011 |
20120150280 | LONGITUDINALLY FLEXIBLE EXPANDABLE STENT - Segmented articulatable stent of open structure comprised of end-connected struts of first and second lengths making up first and second segments with angular interconnects between adjacent first and second segments. | 06-14-2012 |
20120185035 | FLEXIBLE AND EXPANDABLE STENT - In one embodiment of the invention, a stent may be provided comprising a first undulating band having alternating peaks and troughs, a second undulating band having alternating peaks and troughs, a first substantially longitudinal connector extending between the first and second undulating bands and a second very short connector extending between the first and second undulating bands, the first connector substantially longer than the second very short connector. | 07-19-2012 |
20130138138 | Occlusion Device - An occlusion device (e.g., for treatment of the left atrial appendage) includes a framework and a biocompatible covering disposed over at least a part of the framework. The framework may include a proximal portion, a middle portion, and a distal portion, wherein: the proximal portion includes a first hub that has a fixed first diameter; the middle portion has a second diameter and includes a plurality of beams extending from the first hub to a distal portion, wherein each of the plurality of beams is connected to an adjacent beam by a first circumferentially extending column of strut pairs; and the distal portion has a third diameter. In one or more embodiments, the framework includes improved circumferential strength and minimizes foreshortening. | 05-30-2013 |
20130204348 | LONGITUDINALLY FLEXIBLE EXPANDABLE STENT - Segmented articulatable stent of open structure comprised of end-connected struts of first and second lengths making up first and second segments with angular interconnects between adjacent first and second segments. | 08-08-2013 |
20140018841 | OCCLUSION DEVICE FOR AN ATRIAL APPENDAGE - Occlusion device for an atrial appendage, the device having proximal and distal ends and a central axis and comprising a cage-like structure formed of struts, the struts having proximal strut ends and distal strut ends, wherein at the proximal end of the device the struts extend towards the central axis and are connected to each other at their proximal strut ends, and wherein at least some of the struts are connected to each other at their distal strut ends within the cage-like structure so that the struts form an atraumatic distal end of the device. | 01-16-2014 |
Tom Ley, Cupertino, CA US
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20080284047 | Chip Package with Stiffener Ring - Various semiconductor chip packages and methods of making the same are provided. In one aspect, a method of manufacturing is provided that includes providing a substrate that has a first side and a first plurality of passive devices in the first side. A polymeric stiffener ring is formed on the first side. The stiffener ring embeds the first plurality of passive devices without covering a central portion of the first surface of the substrate. A semiconductor chip is mounted on the central portion of the first surface of the substrate. | 11-20-2008 |
20090200659 | Chip Package with Channel Stiffener Frame - Various semiconductor chip packages and methods of making the same are provided. In one aspect, a method of manufacturing is provided that includes providing a substrate that has a first side and a first plurality of passive devices on the first side. A stiffener frame is coupled on the first side. The stiffener frame has first and second spaced apart opposing walls that define a channel in which the first plurality of passive devices is positioned, and a central opening that does not cover a central portion of the first side of the substrate. | 08-13-2009 |
20110241161 | CHIP PACKAGE WITH CHANNEL STIFFENER FRAME - Various semiconductor chip packages and methods of making the same are provided. In one aspect, a method of manufacturing is provided that includes providing a substrate that has a first side and a first plurality of passive devices on the first side. A stiffener frame is coupled on the first side. The stiffener frame has first and second spaced apart opposing walls that define a channel in which the first plurality of passive devices is positioned, and a central opening that does not cover a central portion of the first side of the substrate. | 10-06-2011 |
Tom J. Ley, Cupertino, CA US
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20130258619 | STIFFENER FRAME WITH CIRCUIT BOARD CORNER PROTECTION - Various circuit boards and stiffener frames and methods of making the same are disclosed. In one aspect, a method of manufacturing is provided that includes fabricating a stiffener frame that has a surface adapted to engage a side of a circuit board. The surface includes a projection to protect a corner of the circuit board. | 10-03-2013 |
Vance Ley, Albuquerque, NM US
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20090155951 | Exponentially Doped Layers In Inverted Metamorphic Multijunction Solar Cells - A method of forming a multijunction solar cell including an upper subcell, a middle subcell, and a lower subcell, including providing first substrate for the epitaxial growth of semiconductor material; forming a first solar subcell on the substrate having a first band gap; forming a second solar subcell over the first solar subcell having a second band gap smaller than the first band gap; forming a grading interlayer over the second subcell, the grading interlayer having a third band gap greater than the second band gap; and forming a third solar subcell over the grading interlayer having a fourth band gap smaller than the second band gap such that the third subcell is lattice mis-matched with respect to the second subcell, wherein at least one of the bases of a solar subcell has an exponentially doped profile. | 06-18-2009 |
20090155952 | Exponentially Doped Layers In Inverted Metamorphic Multijunction Solar Cells - A method of forming a multifunction solar cell including an upper subcell, a middle subcell, and a lower subcell, including providing first substrate for the epitaxial growth of semiconductor material; forming a first solar subcell on the substrate having a first band gap; forming a second solar subcell over the first solar subcell having a second band gap smaller than the first band gap; forming a grading interlayer over the second subcell, the grading interlayer having a third band gap greater than the second band gap; and forming a third solar subcell over the grading interlayer having a fourth band gap smaller than the second band gap such that the third subcell is lattice mismatched with respect to the second subcell, wherein at least one of the bases of a solar subcell has an exponentially doped profile. | 06-18-2009 |