Patent application number | Description | Published |
20110124697 | COMPOSITIONS BASED ON AMINOACIDS, SUITABLE FOR THE TREATMENT OF HEART FAILURE - Compositions based on amino acids are described, in particular for oral or parenteral use, suitable for treating heart insufficiency. The compositions according to the invention comprise up to 75% of the branched chain amino acids leucine, isoleucine and valine, as active ingredients. Preferably, the compositions also comprise, as further active ingredients, up to 50% of theronine and lysine. Other essential amino acids are preferably also provided (in particular methionine, phenylalanine, histidine, triphtophan) as well as non essential amino acids (in particular tyrosine and/or cyst(e)ine—i.e., cystine and cyst(e)ine). Other amino acids can be added, provided that their sum is in a percentage being lower than 20% with respect to the other active ingredients, and less than 10% for each single amino acid. | 05-26-2011 |
20110245312 | AMINO ACID BASED COMPOSITIONS FOR THE TREATMENT OF PATHOLOGICAL CONDITIONS DISTINGUISHED BY INSUFFICIENT MITOCHONDRIAL FUNCTION - The present invention relates to compositions suitable for the treatment of pathological conditions distinguished by insufficient or reduced mitochondrial function. The compositions comprise, as principal active ingredients, the amino acids leucine, isoleucine and valine. The compositions may also comprise, as further active ingredients, amino acids threonine and lysine, and optionally, histidine, phenylalanine, methionine, tryptophan, as well as tyrosine and cysteine. | 10-06-2011 |
20110245313 | AMINO ACID BASED COMPOSITIONS FOR THE TREATMENT OF PATHOLOGICAL CONDITIONS DISTINGUISHED BY INSUFFICIENT MITOCHONDRIAL FUNCTION - The present invention relates to compositions suitable for the treatment of pathological conditions distinguished by insufficient or reduced mitochondrial function. The compositions comprise, as principal active ingredients, the amino acids leucine, isoleucine and valine. The compositions may also comprise, as further active ingredients, amino acids threonine and lysine, and optionally, histidine, phenylalanine, methionine, tryptophan, as well as tyrosine and cysteine. | 10-06-2011 |
20120316217 | COMBINATION FOR THE TREATMENT OF OSTEOARTHRITIS - The present invention relates to the use of a combination of glycine, proline, and optionally a natural or synthetic viscosity-controlling polymer, and/or lysine and/or leucine, to prepare a composition for the treatment of osteoarthritis. | 12-13-2012 |
20130018080 | COMPOSITIONS COMPRISING AMINO ACIDS FOR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASEAANM Dioguardi; Francesco SaverioAACI MilanoAACO ITAAGP Dioguardi; Francesco Saverio Milano ITAANM Mella; Isabella ArborioAACI MilanoAACO ITAAGP Mella; Isabella Arborio Milano ITAANM Conti; Edoardo Carlo MariaAACI MilanoAACO ITAAGP Conti; Edoardo Carlo Maria Milano ITAANM Conti; Giovanni Federico MariaAACI MilanoAACO ITAAGP Conti; Giovanni Federico Maria Milano IT - A composition comprising leucine, isoleucine, valine, threonine and lysine for treating chronic obstructive pulmonary disease. | 01-17-2013 |
20130039881 | COMBINATION FOR THE TREATMENT OF RADIATION- OR CHEMOTHERAPY-INDUCED MUCOSITIS - The present invention relates to the use of a combination of glycine, proline, and optionally a natural or synthetic film-forming polymer, and/or lysine and/or leucine, to prepare a composition for the treatment of mucositis induced by radiation or chemotherapy. | 02-14-2013 |
20130085170 | COMPOSITIONS COMPRISING AMINO ACIDS, WITH PRO-ANGIOGENIC ACTIVITY - Composition comprising leucine, isoleucine, valine threonine and lysine for treating angiogenic disorders in elderly subjects. | 04-04-2013 |
20130237577 | COMPOSITIONS COMPRISING AMINO ACIDS FOR PREVENTION AND/OR TREATMENT OF RENAL DISORDERS - Composition comprising leucine, isoleucine, valine, threonine and lysine for use in prophylactic and/or therapeutic treatment of renal disorders in a subject, preferably an elderly subject. | 09-12-2013 |
20130310437 | COMBINATION FOR THE TREATMENT OF OSTEOARTHRITIS - The present invention relates to the use of a combination of glycine, proline, and optionally a natural or synthetic viscosity-controlling polymer, and/or lysine and/or leucine, to prepare a composition for the treatment of osteoarthritis. | 11-21-2013 |
20140206736 | COMPOSITIONS COMPRISING AMINO ACIDS FOR PREVENTION AND/OR TREATMENT OF RENAL DISORDERS - Composition comprising leucine, isoleucine, valine, threonine and lysine for use in prophylactic and/or therapeutic treatment of renal disorders in a subject, preferably an elderly subject. | 07-24-2014 |
20140371289 | COMPOSITION FOR ELIMINATION OF TROUBLESOME VARMINTS - Composition for elimination of troublesome varmints comprises all the non-essential amino acids alanine, glycine, proline, serine, tyrosine, aspartic acid, asparagine, glutamic acid. | 12-18-2014 |
20150079009 | COMBINATION FOR THE TREATMENT OF RADIATION- OR CHEMOTHERAPY-INDUCED MUCOSITIS - The present invention relates to the use of a combination of glycine, proline, and optionally a natural or synthetic film-forming polymer, and/or lysine and/or leucine, to prepare a composition for the treatment of mucositis induced by radiation or chemotherapy. | 03-19-2015 |
Patent application number | Description | Published |
20100291461 | PREPARATION OF NANOSTRUCTURED THIN CATALYTIC LAYER-BASED ELECTRODE INK - A method of making an electrode ink containing nanostructured catalyst elements is described. The method comprises providing an electrocatalyst decal comprising a carrying substrate having a nanostructured thin catalytic layer thereon, the nanostructure thin catalytic layer comprising nanostructured catalyst elements; providing a transfer substrate with an adhesive thereon; transferring the nanostructured thin catalytic layer from the carrying substrate to the transfer substrate; removing the nanostructured catalyst elements from the transfer substrate; providing an electrode ink solvent; and dispersing the nanostructured catalyst elements in the electrode ink solvent. Electrode inks, coated substrates, and membrane electrode assemblies made from the method are also described. | 11-18-2010 |
20100291463 | ELECTRODE CONTAINING NANOSTRUCTURED THIN CATALYTIC LAYERS AND METHOD OF MAKING - A method of transferring a nanostructured thin catalytic layer from its carrying substrate to a porous transfer substrate and further processing and restructuring the nanostructured thin catalytic layer on the porous transfer substrate is provided. The method includes transferring the nanostructured catalytic layer from its carrying substrate to a transfer substrate. The nanostructured catalytic layer then is processed and reconstructed, including removing the residual materials and adding additional components or layers to the nanostructured catalytic layer, on the transfer substrate. Methods of fabricating catalyst coated membranes with the reconstructed electrode including the nanostructured thin catalytic layer, reconstructed electrode decals, and catalyst coated proton exchange membranes are also described. | 11-18-2010 |
20100291467 | FABRICATION OF CATALYST COATED DIFFUSION MEDIA LAYERS CONTAINING NANOSTRUCTURED THIN CATALYTIC LAYERS - A method of transferring nanostructured thin catalytic layers to a gas diffusion layer and thus making a catalyst coated diffusion media is described. The method includes treating the gas diffusion layer with a temporary adhesive to temporarily increase the adhesion strength within the microporous layer and to carbon fiber paper substrate, transferring the nanostructured thin catalytic layer to the microporous side of a gas diffusion media layer. The nanostructured thin catalytic layer can then be further processed, including adding additional components or layers to the nanostructured thin catalytic layer on the gas diffusion media layer. Preparation of catalyst coated diffusion media and a catalyst coated diffusion media based membrane electrode assembly (MEA) are also described. | 11-18-2010 |
20100291473 | FABRICATION OF ELECTRODES WITH MULTIPLE NANOSTRUCTURED THIN CATALYTIC LAYERS - A method of making a reconstructed electrode having a plurality of nanostructured thin catalytic layers is provided. The method includes combining a donor decal comprising at least one nanostructured thin catalytic layer on a substrate with an acceptor decal comprising a porous substrate and at least one nanostructured thin catalytic layer. The donor decal and acceptor decal are bonded together using a temporary adhesive, and the donor substrate is removed. The temporary adhesive is then removed with appropriate solvents. Catalyst coated proton exchange membranes and catalyst coated diffusion media made from the reconstructed electrode decals having a plurality of nanostructured thin catalytic layers are also described. | 11-18-2010 |
20110236788 | METHOD FOR MEMBRANE ELECTRODE ASSEMBLY FABRICATION AND MEMBRANE ELECTRODE ASSEMBLY - A method of coating carbon based electrodes and thick electrodes without mud-cracking is described. The electrode ink is deposited on a decal substrate, and transferred to a hot press before the electrode ink is completely dried. The partially dried electrode ink is hot pressed to the membrane to form a membrane electrode assembly. A membrane electrode assembly including a polymer membrane; and a pair of crack-free electrode layers on opposite sides of the polymer membrane, each of the pair of electrode layers having a thickness of at least about 50 μm is also described. | 09-29-2011 |
20110294037 | ELECTRODE CONTAINING NANOSTRUCTURED THIN CATALYTIC LAYERS AND METHOD OF MAKING - A method of making an electrode is provided. The method includes providing an electrocatalyst decal comprising a carrying substrate having a nanostructured thin catalytic layer thereon; providing a transfer substrate with an adjacent adhesive layer; adhering the nanostructured thin catalytic layer adjacent to the adhesive layer to form a composite structure; removing the carrying substrate from the composite structure; and removing the transfer substrate from the composite structure to form the stand-alone nanostructured thin catalytic film comprising the adhesive layer with the nanostructured thin catalytic layer adhered thereto. A stand alone nanostructured thin catalytic film and methods of constructing electrodes with the stand alone nanostructured thin catalytic films are also described. | 12-01-2011 |
20120244452 | DIRECT CATALYST COATING ON FREE STANDING MICROPOROUS LAYER - Methods of making reinforced membrane electrode assemblies are described. Catalyst coated free standing microporous layers and reinforced membrane electrode assemblies are also described. | 09-27-2012 |
20130236810 | Fuel Cell Durability By Orthogonally Oriented Anisotropic External Reinforce Layers - A fuel cell includes a proton exchange membrane having a first major side and a second major side. The membrane electrode assembly includes a first anisotropic reinforced layer having a first plurality of fiber preferentially oriented along a first direction, a second anisotropic reinforced layer having a second plurality of fiber preferentially oriented along a second direction, and a polymeric layer including a plurality of sulfonic acid groups. A cathode catalyst layer is disposed over the first major side of the proton exchange membrane while an anode catalyst layer is disposed over the second major side of the proton exchange membrane. An anode flow field plate is disposed over the anode catalyst layer and a cathode flow field plate is disposed over the cathode catalyst layer. | 09-12-2013 |
20130260278 | PREPARATION OF NANOSTRUCTURED THIN CATALYTIC LAYER-BASED ELECTRODE INK - A method of making an electrode ink containing nanostructured catalyst elements is described. The method comprises providing an electrocatalyst decal comprising a carrying substrate having a nanostructured thin catalytic layer thereon, the nanostructure thin catalytic layer comprising nanostructured catalyst elements; providing a transfer substrate with an adhesive thereon; transferring the nanostructured thin catalytic layer from the carrying substrate to the transfer substrate; removing the nanostructured catalyst elements from the transfer substrate; providing an electrode ink solvent; and dispersing the nanostructured catalyst elements in the electrode ink solvent. Electrode inks, coated substrates, and membrane electrode assemblies made from the method are also described. | 10-03-2013 |
20140120458 | Direct Coated Membrane Electrode Assembly On External Reinforcement For Fuel Cells - Disclosed are methods for fabricating a reinforced membrane electrode assembly having one or more freestanding external reinforcement layers. The method comprises providing a freestanding external reinforcement layer, and depositing a catalyst solution and membrane solution onto at least a portion of the freestanding external reinforcement layer. | 05-01-2014 |
Patent application number | Description | Published |
20090022388 | METHOD AND APPARATUS FOR ANALYZING CLUSTERS OF OBJECTS - The present invention relates to a method and an apparatus for processing and metrically quantifying images of objects containing clusters of points/spots, such as biological specimens comprising cluster of cells, in particular of human or animal origin, or images thereof. In particular, the present invention relates to a method for processing images of irregularly shaped objects in the form of at least one cluster of punctiform or spot-shaped objects, comprising a stage of acquisition of a digital image of said objects, a stage of image elaboration (IMA-EL) for quantizing said digital image to 1 bit and a stage of metrical processing of said 1-bit quantized image, wherein said stage of metrical processing comprises a stage of object's metrical quantification (QUANT) that on its turn comprises:
| 01-22-2009 |
20090232382 | "IN VITRO" DIAGNOSTIC METHOD FOR DISEASES AFFECTING HUMAN OR ANIMAL TISSUES - The present invention relates to an “in vitro” diagnostic method for diseases affecting human or animal tissues, in particular for the diagnosis of diseases involving inflammation and fibrosis in human or animals, more particularly for liver diseases. More particularly, the present invention relates to a method for diagnosing “in vitro” abnormal morphological conditions in human or animal tissues affected by a chronic inflammatory disease, which comprises observing an image of a biopsy sample of the human or animal body in which said abnormal condition can be detected and metrically quantifying said abnormal morphological condition, wherein said step of metrically quantifying comprises detecting the extent of the fibrotic and of the inflammatory tissue by means of: i) calculating the fractal corrected perimeter (Pf) and/or area (Af) of the collagen islets, and ii) calculating the percentage area of the clustered inflammatory cells by means of the formula ACINF/AB·100, wherein ACiNF is the actual area of the inflammatory cells belonging to clusters and AB is the area of the biopsy sample. | 09-17-2009 |