Ligon
Aaron Ligon, Millbrae, CA US
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20120150695 | Apparatuses, Methods and Systems for an Online Rewards Incentive Program - Software on a server receives a game action message associated with one of a plurality of online games being played by a user. The software generates an asset message based at least in part on the game action message. The software determines user feed preferences based on a social filter graph. The social filter graph depends at least in part on a metagame account associated with the user. And the software transmits the asset message to social network identifiers according to the user feed preferences. | 06-14-2012 |
Azra H. Ligon, Brookline, MA US
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20160032359 | Methods for Generating Nucleic Acid Molecule Fragments Having a Customized Size Distribution - The invention provides methods for generating nucleic acid molecule fragments having a customized distribution. In one aspect, a method of generating nucleic acid fragments having a customized fragment size distribution is provided comprising obtaining a master pool of nucleic acid molecules to be fragmented; fragmenting at least two independent aliquots of the master pool of nucleic acid molecules in separate reactions, wherein the fragmentation conditions are identical except for a single variable. | 02-04-2016 |
Brook Ligon US
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20110269802 | METHOD OF DELIVERY OF PERISHABLE LIQUID MIXTURES USING MIXING CAP AND CONTAINER SYSTEM - Methods for preparing and delivering perishable liquid mixtures comprising at least one active ingredient. The methods use systems comprising vessels having novel barriers for segregating solvent liquids from active ingredients prior to preparation. Novel liquid mixtures having therapeutic properties are also disclosed. | 11-03-2011 |
Brooke Ligon US
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20110266170 | MIXING CAP AND CONTAINER SYSTEM FOR IMPROVED DELIVERY OF PERISHABLE LIQUID MIXTURES - System and compositions for preparing and delivering perishable liquid mixtures comprising at least one active ingredient. The system comprises vessels having novel barriers for segregating solvent liquids from active ingredients prior to preparation. Novel liquid mixtures having therapeutic properties are also disclosed. | 11-03-2011 |
Brooke Ligon, Sullivan, ME US
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20080318908 | USE OF GABA AND GABAB AGONISTS - The present invention provides methods of stimulating tissue growth, including islet cell growth, by administering GABA or a GABA agonist to act on GABA | 12-25-2008 |
20130252886 | METHODS OF DELAYING AND TREATING DIABETES - The present invention provides methods of treating hyperglycemia and delaying the onset of diabetes, comprising administering to a mammal in need thereof a therapeutically effective amount of a GABA receptor agonist at or near a time of an exogenous insulin administration or a meal. | 09-26-2013 |
Charles R. Ligon, Bradentown, FL US
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20140199517 | Enhanced friction coating construction and method for forming same - A method for forming a friction coating construction which utilizes the providing of a mixture of molten metal material with abrasive particles dispersed therethroughout in particulant form which is sprayed onto a flexible substrate which is of a metallic material being preferably ductile which is then allowed to harden and cool to allow the molten metal to affix the flexible support layer with respect to the metal material and with respect to the abrasive particles dispersed therethroughout thereby providing an enhanced friction control surface which can optionally include an adhesive layer on the surface of the flexible substrate positioned oppositely from the abrasive particles to allow this layer to be affixed to any subsurface surface which needs enhanced control of the coefficient of friction thereto. | 07-17-2014 |
David Ligon, San Francisco, CA US
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20080208281 | Device and method for biasing and stimulating respiration - A device and method is provided for biasing lung volume by electrically stimulating tissue associated with the diaphragm or phrenic nerve at a low level. | 08-28-2008 |
20080215106 | Thoracoscopically implantable diaphragm stimulator - A diaphragm stimulator is provided to treat one or more diseases disorders or conditions where the stimulator is configured to be implanted by way of a thoracoscopic approach to the diaphragm. The stimulator may include sensors positioned within the thorax. The stimulator may also include or be used with a cardiac rhythm management device. | 09-04-2008 |
20080288015 | Diaphragm stimulation device and method for use with cardiovascular or heart patients - A method for treating a patient is provided where a sensed cardiac rhythm is used to adjust electrical stimulation that is used to activate a diaphragm to cause contraction. A cardiac rhythm management device in combination with a diaphragm stimulation device is also provided which includes a cardiac stimulation device configured to provide stimulation to control cardiac rhythm of a subject; and an electrical stimulation device configured to provided electrical stimulation to a subject to activate a diaphragm to increase functional residual capacity of the subject. | 11-20-2008 |
20110230932 | DEVICE AND METHOD FOR INDEPENDENTLY STIMULATING HEMIDIAPHRAGMS - A device and method for treating a subject is provided where electrical stimulation may be separately provided to each hemidiaphragm to cause diaphragm contraction. Fatigue may be avoided among other possible benefits. Each hemidiaphragm may also be stimulated with different stimulation parameters. Stimulation may be smoothly transitioned between hemidiaphragms. Such stimulation may provide an increase in functional residual capacity or other therapeutic effects. | 09-22-2011 |
20120109249 | MULTIMODE DEVICE AND METHOD FOR CONTROLLING BREATHING - A device and method is provided for therapeutic stimulating, augmenting, manipulating and/or controlling breathing, in combination with stimulation of auxiliary respiratory nerves or muscles including the upper airway tract, chest wall muscles or abdominal muscles. Stimulation may be provided, for example, to augment breathing or to prevent closing of the upper airway during therapeutic stimulation. Stimulation may be also provided to the Hypoglossal nerve during exhalation. | 05-03-2012 |
20120158091 | THERAPEUTIC DIAPHRAGM STIMULATION DEVICE AND METHOD - A device and method for treating a variety of conditions, disorders or diseases with diaphragm/phrenic nerve stimulation is provided. | 06-21-2012 |
20130197601 | DEVICE AND METHOD FOR INDEPENDENTLY STIMULATING HEMIDIAPHRAGMS - A device and method for treating a subject is provided where electrical stimulation may be separately provided to each hemidiaphragm to cause diaphragm contraction. Fatigue may be avoided among other possible benefits. Each hemidiaphragm may also be stimulated with different stimulation parameters. Stimulation may be smoothly transitioned between hemidiaphragms. Such stimulation may provide an increase in functional residual capacity or other therapeutic effects. | 08-01-2013 |
20130296973 | BREATHING THERAPY DEVICE AND METHOD - A device and method is provided for electrically stimulating the diaphragm to control breathing while inhibiting respiratory drive. A stimulation phase is identified. The stimulation phase is it period of time within the breathing cycle in which stimulation will inhibit respiratory drive. The respiratory drive inhibition may be used in a number of applications including but not limited to: improving or remodeling the heart in heart failure patients, treating apnea, chronic obstructive pulmonary disorder (COPD), and hypertension. | 11-07-2013 |
Keith L. Ligon, Brookline, MA US
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20160032359 | Methods for Generating Nucleic Acid Molecule Fragments Having a Customized Size Distribution - The invention provides methods for generating nucleic acid molecule fragments having a customized distribution. In one aspect, a method of generating nucleic acid fragments having a customized fragment size distribution is provided comprising obtaining a master pool of nucleic acid molecules to be fragmented; fragmenting at least two independent aliquots of the master pool of nucleic acid molecules in separate reactions, wherein the fragmentation conditions are identical except for a single variable. | 02-04-2016 |
Mary Louisa Ligon, Almont, MI US
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20150260207 | ELASTIC CLIP - An elastic clip that is functional, inexpensive to produce, requires no tools to use, and allows the user many options on how to use it. It can be used as an adjustable clip with a single elongated member and a keeper. It can be used to fasten together parallel parts with the use of a keeper. Finally, it can fasten together perpendicular members with the perpendicular member parallel to the bend in the nose taking the place of the keeper. Pinching the two handles together allows the user to insert the desired components into the elastic clip and releasing the two handles causes the handles to spring apart forcing the edges of the orifice to apply pressure to the elongated member pushing all the components toward the nose locking everything into an assembled relation. | 09-17-2015 |
Paul Jerry Ligon, The Woodlands, TX US
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20100185506 | SYSTEMS AND METHODS USED IN THE OPERATION OF A RECYCLING ENTERPRISE - A system and computer program product for managing an online recycling operation, including uniquely associating one or more recyclable products with unique identifiers and other product information stored in a database, receiving information associated with the one or more recyclable products, periodically storing and updating the information associated with the one or more recyclable products in the database, associating the unique identifier with a recycling user having user account information stored in the database, updating the reward point total based on an activity of the recycling user, communicating the product information and the user account information to the recycling user over a network, communicating rewards that are available in exchange for reward points to the recycling user over the network, and redeeming reward points upon demand by the recycling user over the network. Each recyclable product includes indicia that uniquely identifies the recyclable product. The user account information includes user information comprising a reward point total and recycling data associated with the recycling user. The activity includes recycling activities and active participation on an environmentally-friendly web server. | 07-22-2010 |
20110225098 | SYSTEMS AND METHODS USED IN THE OPERATON OF A RECYCLING ENTERPRISE - A system and computer program product for communicating with a recycling user during recycling activities of a recycling vehicle, including: receiving recycling user information, associated with a recycling user via a web-based user interface, having a street address, contact information, a reward point total and recycling data associated with the recycling user; associating a unique identifier with the recycling user; periodically storing and updating the recycling user information in an account identified by the unique identifier in the database; converting the street address into a recycling user geographic coordinate; periodically receiving a recycling vehicle geographic coordinate associated with the real-time location of a recycling vehicle via a wireless network; comparing the received recycling vehicle geographic coordinate with the recycling user geographic coordinate and determining whether the received recycling vehicle geographic coordinate associated with the recycling user geographic coordinate are within a predefined geographic distance of each other; retrieving the account of the recyclable user within the determined predefined geographic distance; and transmitting an electronic communication over a network to an electronic address identified by the contact information associated with the account of the recyclable user. | 09-15-2011 |
Robert J. Ligon, Frankfort, IL US
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20080313998 | METHOD OF MANFACTURE FOR A SQUEEZABLE FLEXIBLE PACKAGE - A method and apparatus for manufacturing a non-rectilinear flexible package comprising an in-line process including application and selective sealing of a semi-rigid strip to an inner wall of the package and further including a dual-stage die-cutting technique to remove and cut a non-linear shape into a formed web of film. The semi-rigid strip is sealed to one interior wall of the package but not the other to provide a reinforced opening to the package through which a material can be dispensed. Additionally, the dual stage die-cutting method comprises first cutting and removing a portion of the web material prior to filling the package and again cutting and removing a portion of the web material after filling, resulting in a package having a narrowed neck adjacent the closed reinforced opening at an upper portion of the package and a body of the package that is tapered towards the reinforced opening. | 12-25-2008 |
20110146208 | Method of Manufacture for a Squeezable Flexible Package - A method and apparatus for manufacturing a non-rectilinear flexible package comprising an in-line process including application and selective sealing of a semi-rigid strip to an inner wall of the package and further including a dual-stage die-cutting technique to remove and cut a non-linear shape into a formed web of film. The semi-rigid strip is sealed to one interior wall of the package but not the other to provide a reinforced opening to the package through which a material can be dispensed. Additionally, the dual stage die-cutting method comprises first cutting and removing a portion of the web material prior to filling the package and again cutting and removing a portion of the web material after filling, resulting in a package having a narrowed neck adjacent the closed reinforced opening at an upper portion of the package and a body of the package that is tapered towards the reinforced opening. | 06-23-2011 |
20120144780 | Method of Manufacture for a Squeezable Flexible Package - A method and apparatus for manufacturing a non-rectilinear flexible package comprising an in-line process including application and selective sealing of a semi-rigid strip to an inner wall of the package and further including a dual-stage die-cutting technique to remove and cut a non-linear shape into a formed web of film. The semi-rigid strip is sealed to one interior wall of the package but not the other to provide a reinforced opening to the package through which a material can be dispensed. Additionally, the dual stage die-cutting method comprises first cutting and removing a portion of the web material prior to filling the package and again cutting and removing a portion of the web material after filling, resulting in a package having a narrowed neck adjacent the closed reinforced opening at an upper portion of the package and a body of the package that is tapered towards the reinforced opening. | 06-14-2012 |
Samuel Clark Ligon, Vienna AT
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20120255894 | METHOD FOR COVALENTLY ATTACHING POLYMERIC MONOLITHS TO POLYETHER ETHER KETONE (PEEK) SURFACES - Method for covalently attaching polymeric monoliths to polyether ether ketone (PEEK) surfaces The present invention provides a method of covalently attaching a polymeric monolith to the internal surface of polyether ether ketone (PEEK) tubing and column housings, comprising the steps of: (a) reducing the ketone group of the PEEK to a hydroxyl group to obtain a modified PEEK, (b) optionally reacting the hydroxyl group obtained in step (a) with a compound having an active vinyl group to form a modified PEEK selected from the group of acrylate modified PEEK, methacrylate modified PEEK, styrene modified PEEK and epoxy modified PEEK, and (c) reacting the modified PEEK obtained in step (a) or (b) with a polymer or polymerization mixture for forming the polymeric monolith. Hereby, the mechanical stability and solvent durability of larger diameter monolithic columns as well as their overall performance are improved. | 10-11-2012 |
Timothy D. Ligon, Saint Albans, WV US
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20110172462 | CONTROL OF A PROCESS FOR THE PURIFICATION OF (METH)ACRYLIC ACID USING ON-LINE, NEAR IR ANALYSIS - An improved process for the manufacture of technical grade (meth)acrylic acid, e.g., acrylic acid, the process comprising producing a hydrated reaction product from the gas-phase oxidation of at least one (meth)acrylic acid precursor, e.g., propylene, followed by first dehydrating and then concentrating the reaction product, the improvement comprising controlling at least one of the water, acetic acid and (meth)acrylic acid content of the reaction product during the purification of the reaction product using on-line, near IR spectroscopy. | 07-14-2011 |
Timothy D. Ligon, St. Albans, WV US
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20090318735 | PREPARATION OF GLUTARALDEHYDE - Provided is a process for the preparation of glutaraldehyde. The process comprises reacting an alkoxydihydropyran with water in the presence of an acidic catalyst. The alcohol by-product distilled from the reaction mixture is subjected to a heterogeneous catalyst that is located external to the distillation column used for distilling the alcohol, thereby increasing glutaraldehyde yield and decreasing the level of alkoxydihydropyran contamination in the alcohol. | 12-24-2009 |