Stevenson, MA
Adam Stevenson, Worcester, MA US
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20150089881 | SHAPED ABRASIVE PARTICLES AND METHODS OF FORMING SAME - A method of forming a shaped abrasive particle includes having a body formed by an additive manufacturing process. | 04-02-2015 |
Alexander Stevenson, Boston, MA US
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20100164983 | LEVERAGING GRAPHICS PROCESSORS TO OPTIMIZE RENDERING 2-D OBJECTS - Methods and computer-readable media for displaying two-dimensional objects on a display device are disclosed. Rendering requests are received from an application to render two-dimensionally modeled graphics to a display device. Primitive geometries of drawing calls of the rendering requests are tessellated into sequences of triangles. The vertices of the triangles are mapped to a vertex buffer along with an index to identify associated constant data. Batching operations store and communicate calls and mapped data to a graphics processing unit by way of a three-dimensional rendering application program interface. Constant data associated with the mapped data are indexed and appended together in a constant buffer, thereby allowing drawing calls to be coalesced. A staging buffer and a staging texture are provided for batching text anti-aliasing operations. Shader fragments are precompiled and organized by way of a predetermined lookup table. | 07-01-2010 |
20130106853 | LEVERAGING GRAPHICS PROCESSORS TO OPTIMIZE RENDERING 2-D OBJECTS | 05-02-2013 |
Cheri Stevenson, Haverhill, MA US
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20130189218 | PHARMACEUTICAL FORMULATIONS FOR FUMAGILLIN DERIVATIVE-PHF CONJUGATES - The invention described herein provides a mixture comprising polymer molecules or salts thereof, wherein a polymer molecule in the mixture comprises covalently bound subunits L, K, and M wherein the average molecular weight of the polymer molecules in the mixture is about 50 kDa to about 200 kDa, wherein the mole percentage of subunit M, K and L, relative to the total amount of subunits in the mixture, is about 90.5 to about 96 mol %, about 2.8 to about 7.3 mol %, and about 1.2 to about 2.2 mol %, respectively. | 07-25-2013 |
Christian P. Stevenson, Boston, MA US
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20110136842 | Substituted Dihydroisoquinolinone and Isoquinolinedione Derivatives as Calcium Channel Blockers - A series of disubstituted dihydroisoquinolinone and isoquinolinedione derivatives represented by Formula I, or pharmaceutically acceptable salts thereof are presented. Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more other therapeutically active compounds, and a pharmaceutically acceptable carrier. Methods of treating conditions associated with, or caused by, calcium channel activity, including, for example, acute pain, chronic pain, visceral pain, inflammatory pain, neuropathic pain, urinary incontinence, itchiness, allergic dermatitis, epilepsy, diabetic neuropathy, irritable bowel syndrome, depression, anxiety, multiple sclerosis, sleep disorder, bipolar disorder and stroke, comprise administering an effective amount of the present compounds, either alone, or in combination with one or more other therapeutically active compounds. | 06-09-2011 |
Harold H. Stevenson, Holliston, MA US
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20110080917 | METHOD, PROCESS AND SYSTEM FOR SHARING DATA IN A HETEROGENEOUS STORAGE NETWORK - A method, process and system of controlling the transmission of data in a heterogeneous environment having mainframe based storage using FICON and an open system based storage using FC. The invention bridges the heterogeneous environment while maintaining DASD/Disk neutrality. The bridge is a gateway programmed to permit applications residing on the mainframe or open system to map logic paths thereby eliminating or reducing the need to store data prior to transmission. The gateway is able to appear to the first storage device as a standard CTC connection to a mainframe, while appearing to the open system as a number of SCSI tape drives. | 04-07-2011 |
Jeremy Stevenson, Lexington, MA US
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20090019928 | Metering assembly and method of dispensing fluid - A metering assembly includes a fluidic chip and metering chambers. Selectable outlet valves communicate with each metering chamber to provide a discrete dispensed volume. The valves may be commonly controlled and may be formed as multi-level valves. The valves may be grouped into common substrate valve clusters. Purge channels communicate with the metering chambers and controlled purge valves allow reverse flow wash fluid to wash the metering chamber. Pressure ports are employed to actuate the valves. A method of dispensing a fluid from the fluidic chip includes a) selectively filling (or filling) the metering chambers with a selected fluid; and b) outputting (or selectively outputting) the fluid to output locations. The total output volume of fluid dispensed from each metering chamber may be accumulated. The process may be repeated until the accumulated volume equals the desired volume and may be repeated for another fluid from a plurality of different fluids. | 01-22-2009 |
20100186841 | MICROFLUIDIC DISPENSING ASSEMBLY - A microfluidic dispensing system may include multiple supply lines for simultaneous filling of diaphragm pumps associated with each supply line. Each supply line may fill corresponding groups of diaphragm pumps with a corresponding ingredient to a supply reservoir for the supply line. Accordingly, different groups of diaphragm pumps corresponding to different supply lines may be filled with corresponding ingredients simultaneously. Those ingredients corresponding to the different groups of diaphragm pumps may also be dispensed simultaneously, giving rise to a faster and more efficient fluidic dispensing system. | 07-29-2010 |
20100187452 | MICROFLUIDIC DISPENSING ASSEMBLY - A microfluidic dispensing system may include diaphragm pumps that may be used for aspirating in corresponding ingredients via a nozzle or a tip from supply sources. Tips may be placed in contact with ingredient supply sources, and through repeated actuation of the diaphragm pumps, desired volumes of ingredients are aspirated into the tips. In some cases, an air plug is aspirated into the tips before an ingredient. Once the desired volume of each ingredient is reached within each tip, the ingredients are dispensed from the tips through repeated actuation of corresponding diaphragm pumps. | 07-29-2010 |
20110214768 | METERING ASSEMBLY AND METHOD OF DISPENSING FLUID - A metering assembly includes a fluidic chip and metering chambers. Selectable outlet valves communicate with each metering chamber to provide a discrete dispensed volume. The valves may be commonly controlled and may be formed as multi-level valves. The valves may be grouped into common substrate valve clusters. Purge channels communicate with the metering chambers and controlled purge valves allow reverse flow wash fluid to wash the metering chamber. Pressure ports are employed to actuate the valves. A method of dispensing a fluid from the fluidic chip includes a) to selectively filling (or filling) the metering chambers with a selected fluid; and b) outputting (or selectively outputting) the fluid to output locations. The total output volume of fluid dispensed from each metering chamber may be accumulated. The process may be repeated until the accumulated volume equals the desired volume and may be repeated for another fluid from a plurality of different fluids. | 09-08-2011 |
Jon R. Stevenson, Sudbury, MA US
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20120072968 | ASSESSMENT AND ANALYSIS OF SOFTWARE SECURITY FLAWS IN VIRTUAL MACHINES - Security analysis and vulnerability testing results are “packaged” or “bound to” the actual software it describes. By linking the results to the software itself, downstream users of the software can access information about the software, make informed decisions about implementation of the software, and analyze the security risk across an entire system by accessing all (or most) of the reports associated with the executables running on the system and summarizing the risks identified in the reports. | 03-22-2012 |
Kristen Stevenson, Waltham, MA US
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20140127690 | Mutation Signatures for Predicting the Survivability of Myelodysplastic Syndrome Subjects - Somatic non-silent mutations on selected biomarkers are reliable indicators for the overall survival of Myelodysplastic Syndrome subjects. | 05-08-2014 |
Mario Stevenson, Worcester, MA US
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20090010941 | Methods for treating HIV - The invention relates to methods of treating HIV by administering a TRAIL receptor activator. The invention also relates to methods for inducing apoptosis in an HIV reservoir cell by contacting the cell with TRAIL receptor activator such as an M-CSF effector kinase inhibitor. | 01-08-2009 |
Mario Stevenson, Shrewsbury, MA US
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20110086048 | DETECTION OF HUMAN IMMUNODEFICIENCY VIRUS CO-RECEPTOR TROPISM IN AVIREMIC SUBJECTS - Methods for detecting human immunodeficiency virus (HIV) co-receptor tropism or replication-competent virus in aviremic subjects, and methods of selecting optimal therapies for aviremic subjects. | 04-14-2011 |
Martijn Stevenson, Cambridge, MA US
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20090147297 | System and method for image editing of electronic product design - Electronic document design systems and methods allowing a user engaged in customizing an electronic product to select an image container and modify the placement, scaling, and displayed portion of an image associated with the image container. Upon user selection of an image container from the product design, an image pane is presented to the user which displays the base image associated with the selected image container and at least one active control on either or both of the image container and the image pane which allow the user to modify which portion of, and how the portion of, the base image appears in the electronic product design. The image editor tool is displayed simultaneously with the product design to allow the user to immediately see the resulting changes in the product design due to modifications, using the active control(s), of the placement or scaling of the selected image container or of the cropping of the base image or magnification of the portion of the base image appearing within the image container. | 06-11-2009 |
Matthew Stevenson, Waltham, MA US
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20130037778 | DEVICE INCLUDING QUANTUM DOTS - A method of making a device comprises forming a layer comprising quantum dots over a substrate including a first electrode, fixing the layer comprising quantum dots formed over the substrate, and exposing at least a portion of, and preferably all, exposed surfaces of the fixed layer comprising quantum dots to small molecules. Also disclosed is a method of making a device, the method comprising forming a layer comprising quantum dots over a substrate including a first electrode, exposing the layer comprising quantum dots to small molecules and light flux. A method of making a film including a layer comprising quantum dots, and a method of preparing a device component including a layer comprising quantum dots are also disclosed. Devices, device components, and films are also disclosed. | 02-14-2013 |
Matthew Stevenson, Woburn, MA US
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20140234999 | METHOD FOR PROCESSING DEVICES INCLUDING QUANTUM DOTS AND DEVICES - A method of processing quantum dots is disclosed. The method comprises applying energy to excite the quantum dots to emit light and placing the quantum dots under vacuum after excitation of the quantum dots. Also disclosed is a method of processing a component including quantum dots comprising applying energy to the component including quantum dots to excite the quantum dots to emit light; and placing the component including quantum dots under vacuum after excitation. A method for processing a device is further disclosed, the method comprising applying energy to the device to excite the quantum dots to emit light; and placing the device under vacuum after excitation of the quantum dots. A method for preparing a device is also disclosed. Quantum dots, component, and devices of the methods are also disclosed. | 08-21-2014 |
Susan C. Stevenson, Ashland, MA US
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20090281191 | USE OF ORGANIC COMPOUNDS - Use of a ERRγ agonist Or pharmaceutically acceptable salt thereof, for the prevention, delay of progression or the treatment of diabetes, insulin resistance, metabolic disease/metabolic syndrome, dyslipdemia, obesity, overweight, Neurodegenerative diseases such as Parkinson's disease. Alzheimer's disease, Huntington's disease or improvement of exercise endurance capacity. | 11-12-2009 |
Susan C. Stevenson, Cambridge, MA US
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20100104584 | GENES INVOLVED IN MITOCHONDRIAL BIOGENESIS - The invention discloses suitable gene and polypeptide targets for the development of new therapeutics to treat, prevent or ameliorate conditions associated with mitochondrial dysfunction. The invention also relates to methods to treat, prevent or ameliorate said conditions and pharmaceutical compositions therefor, as well as to a method to identify compounds with therapeutic usefulness to treat conditions associated with mitochondrial dysfunction. | 04-29-2010 |
William G. Stevenson, Needham, MA US
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20090069808 | METHOD FOR ABLATING WITH NEEDLE ELECTRODE - A method for ablating tissue in or around the heart to create an enhanced lesion is provided. The distal end of a catheter including a needle electrode at its distal end is introduced into the heart. The distal end of the needle electrode is introduced into the tissue. An electrically-conductive fluid is infused through the needle electrode and into the tissue. The tissue is ablated after and/or during introduction of the fluid into the tissue. The fluid conducts ablation energy within the tissue to create a larger lesion than would be created without the introduction of the fluid. | 03-12-2009 |