Jegla
Timothy J. Jegla, La Jolla, CA US
Patent application number | Description | Published |
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20090175882 | METHODS AND COMPOSITIONS FOR TREATING HYPERALGESIA - This invention provides compounds which specifically inhibit TRPA1 but not other members of the thermoTRP ion channel family. Also provided in the invention are methods of using TRPA1-specific inhibitors to treat or alleviate pains mediated by noxious mechanosensation. | 07-09-2009 |
Timothy James Jegla, Durham, NC US
Patent application number | Description | Published |
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20100267930 | SLO2 and SLO4, Novel Potassium Channel Proteins from Human Brain - The invention provides isolated nucleic acid and amino acid sequences of Slo2 and Slo4, members of the Slo family of potassium channel proteins, also known as “maxi” or BK potassium channel proteins. Also provided herein are antibodies to Slo2 and Slo 4, methods of detecting Slo2 and Slo 4, methods of screening for potassium channel activators and inhibitors using biologically active Slo2 and Slo 4, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising Slo2 and Slo 4. | 10-21-2010 |
Timothy James Jegla, San Diego, CA US
Patent application number | Description | Published |
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20090017534 | SLO2 AND SLO4, NOVEL POTASSIUM CHANNEL PROTEINS FROM HUMAN BRAIN - The invention provides isolated nucleic acid and amino acid sequences of Slo2 and Slo4, members of the Slo family of potassium channel proteins, also known as “maxi” or BK potassium channel proteins. Also provided herein are antibodies to Slo2 and Slo 4, methods of detecting Slo2 and Slo 4, methods of screening for potassium channel activators and inhibitors using biologically active Slo2 and Slo 4, and kits for screening for activators and inhibitors of voltage-gated potassium channels comprising Slo2 and Slo 4. | 01-15-2009 |