Patent application number | Description | Published |
20080203130 | EXPANDER ROLLER - A roller for a web-processing machine, the roller having a support core, which is braced in the region of both its ends via a respective bearing arrangement, and an outer covering, which in its axially central region is mounted in a radially fixed manner in relation to the support core and in the region of its two ends is braced in a radially displaceable manner in relation to the support core by a respective additional bearing arrangement, whereby the outer covering is displaceable in the region of its two ends respectively by an actuator arranged within the outer covering, the actuator being adjustable and including two inter-mounted eccentrics to which is assigned respectively one pivoting device, whereby the two pivoting devices are controllable such that the size of the resulting eccentricity and the position of the resulting eccentricity are adjustable preferably separately from each other. | 08-28-2008 |
20080207419 | EXPANDER ROLLER - A roller for a web-processing machine has a support core, which is braced in the region of both its ends via a respective bearing arrangement, and an outer covering, which in its axially central region is braced in a radially fixed manner in relation to the support core and in the region of its two ends is braced in a radially displaceable manner in relation to the support core by a respective additional bearing arrangement, whereby the radially extending center plane of both the support core bearing arrangement and the outer covering bearing arrangement lies axially within the outer covering, and the outer covering is displaceable in the region of its two ends respectively by an actuator arranged preferably within the outer covering. | 08-28-2008 |
20080210733 | EXPANDER ROLLER - A roller, in particular an expander roller, for a web-processing machine, has a support core, which is braced in the region of both its ends via a respective bearing arrangement, and an outer covering, which in its axially central region is braced in a radially fixed manner in relation to the support core and in the region of its two ends is braced in a radially displaceable manner in relation to the support core by a respective additional bearing arrangement, whereby the radially extending center plane of both the support core bearing arrangement and the outer covering bearing arrangement lies axially within the outer covering. Preferably the outer covering is displaceable in this case in the region of its two ends respectively by an actuator arranged within the outer covering. | 09-04-2008 |
20110098166 | EXPANDER ROLLER - A roller for a web-processing machine, the roller having a support core, which is braced in the region of both its ends via a respective bearing arrangement, and an outer covering, which in its axially central region is mounted in a radially fixed manner in relation to the support core and in the region of its two ends is braced in a radially displaceable manner in relation to the support core by a respective additional bearing arrangement, whereby the outer covering is displaceable in the region of its two ends respectively by an actuator arranged within the outer covering, the actuator being adjustable and including two inter-mounted eccentrics to which is assigned respectively one pivoting device, whereby the two pivoting devices are controllable such that the size of the resulting eccentricity and the position of the resulting eccentricity are adjustable preferably separately from each other, the outer covering being non-rotatably connected to the support core. | 04-28-2011 |
Patent application number | Description | Published |
20090017467 | COMPOSITION EXHIBITING A VON WILLEBRAND FACTOR (vWF) PROTEASE ACTIVITY COMPRISING A POLYPEPTIDE CHAIN WITH THE AMINO ACID SEQUENCE AAGGILHLELLV - The invention relates to vWF cleaving entities having a molecular weight of 180 kD, 170 kD, 160 kD, 120 kD or 110 kD and an N-terminal amino acid sequence of AAGGILHLELLV, vWF cleaving complexes and methods for their production. | 01-15-2009 |
20090220521 | Anti MIF Antibodies - The present invention relates to monoclonal antibodies and antigen-binding portions thereof that specifically bind to the C-terminal or the center region of macrophage migration inhibitory factor (MIF). These anti-MIF antibodies and antigen-binding portions thereof further inhibit human MIF biological function. The invention also relates to isolated heavy and light chain immunoglobulins derived from anti-MIF antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to a method of identifying anti-MIF antibodies, pharmaceutical compositions comprising these antibodies and a method of using these antibodies and compositions for the treatment of MIF-related conditions. | 09-03-2009 |
20090221003 | PROCEDURE FOR THE GENERATION OF A HIGH PRODUCER CELL LINE FOR THE EXPRESSION OF A RECOMBINANT ANTI-CD34 ANTIBODY - The present invention relates to cell capture assay for the selection of a high producer cell line expressing anti-CD34 antibodies that recognize the CD34 membrane-protein in the cell membrane. The monoclonal antibody secreted by the hybridoma cell line 9C5/9069 binds to human CD34 and is used to isolate stem cells. The DNA sequences encoding for the antibody heavy and light chain have been identified, isolated from the hybridoma cells and cloned into appropriate expression vectors. After co-transfection of the heavy and light chain genes into HEK293T or in CHO cells either conditioned medium or purified antibody were assessed for binding to CD34 protein located in the cell membrane in different cell capture assays. The binding of the antibody to CD34-positive cells could be shown with these assays for several cell lines. | 09-03-2009 |
20100260768 | ANTI MIF ANTIBODIES - The present invention relates to monoclonal antibodies and antigen-binding portions thereof that specifically bind to the C-terminal or the center region of macrophage migration inhibitory factor (MIF). These anti-MIF antibodies and antigen-binding portions thereof further inhibit human MIF biological function. The invention also relates to isolated heavy and light chain immunoglobulins derived from anti-MIF antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to a method of identifying anti-MIF antibodies, pharmaceutical compositions comprising these antibodies and a method of using these antibodies and compositions for the treatment of MIF-related conditions. | 10-14-2010 |
20140335071 | Composition Exhibiting a von Willebrand Factor (vWF) Protease Activity Comprising a Polypeptide Chain with the Amino Acid Sequence AAGGILHLELLV - The invention relates to vWF cleaving entities having a molecular weight of 180 kD, 170 kD, 160 kD, 120 kD or 110 kD and an N-terminal amino acid sequence of AAGGILHLELLV, vWF cleaving complexes and methods for their production. | 11-13-2014 |
20150023978 | ANTI MIF ANTIBODIES - The present invention relates to monoclonal antibodies and antigen-binding portions thereof that specifically bind to the C-terminal or the center region of macrophage migration inhibitory factor (MIF). These anti-MIF antibodies and antigen-binding portions thereof further inhibit human MIF biological function. The invention also relates to isolated heavy and light chain immunoglobulins derived from anti-MIF antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to a method of identifying anti-MIF antibodies, pharmaceutical compositions comprising these antibodies and a method of using these antibodies and compositions for the treatment of MIF-related conditions. | 01-22-2015 |
20150071942 | COMBINATION THERAPY OF ANTI-MIF ANTIBODIES AND CHEMOTHERAPEUTICS - The present invention pertains to anti-MIF antibodies, in particular their use in combination with therapeutics, i.e. chemotherapeutics, in the treatment of cancer. | 03-12-2015 |
20150160235 | ANTI-MIF IMMUNOHISTOCHEMISTRY - The present invention pertains to the specific detection of MIF, in particular oxMIF, in tissues. A detection method is provided which uses immunohistochemistry and wherein specific anfi-oxMIF antibodies are used. | 06-11-2015 |
20150250873 | COMBINATION THERAPY OF ANTI-MIF ANTIBODIES AND GLUCOCORTICOIDS - The present invention pertains to anti-MIF antibodies, in particular their use in combination with glucocorticoids, in the treatment of glycocorticoid receptive diseases. | 09-10-2015 |