Patent application number | Description | Published |
20090013994 | DELIVERY DEVICE AND RELATED METHODS - Devices for the delivery of medicament. | 01-15-2009 |
20100180894 | DELIVERY DEVICE AND RELATED METHODS - A delivery device that includes a cutter for opening a barrier layer to provide fluid access to a dose chamber, and a diverting structure for direct air flow toward the dose chamber. | 07-22-2010 |
20110083668 | SEALED CAPSULE INCLUDING AN INTEGRATED PUNCTURING MECHANISM - A sealed self-piercing capsule for storing and delivering a substance, such as a medicine, comprises one or more barrier layers forming a sealed chamber for containing the substance. An internal puncturing mechanism is disposed within the capsule chamber for puncturing a barrier layer to release the substance from the chamber. The internal puncturing mechanism may comprise a sharpened edge located on a movable tube, which moves relative to a barrier layer forming the sealed chamber to puncture the barrier layer. | 04-14-2011 |
20110130627 | Visualization Instrument - A visualization instrument comprising a display support component removably coupled to a component insertable into a target space. The insertable component includes a camera providing images of the target space. The images are presented in a display device supported by the display support component. The insertable component may be discarded after a permitted number of uses. | 06-02-2011 |
20110130632 | Visualization Instrument - A visualization instrument comprising a display support component removably coupled to a component insertable into a target space. The insertable component includes a camera providing images of the target space. The images are presented in a display device supported by the display support component. The insertable component may be discarded after a permitted number of uses. | 06-02-2011 |
20120090628 | DEVICE FOR DISPENSING A MEDIUM - A device for dispensing a medium is disclosed. The device comprises an elongated body including a chamber for containing a medium and an outlet through which the medium exits the device into an oral or nasal opening. A dispensing system selectively places the chamber and the outlet in communication, causing medium to flow out of the device. | 04-19-2012 |
20120090629 | DEVICE FOR DISPENSING A MEDIUM - A device for dispensing a medium is disclosed. The device comprises an elongated body including a chamber for containing a medium and an outlet through which the medium exits the device into an oral or nasal opening. A dispensing system selectively places the chamber and the outlet in communication, causing medium to flow out of the device. | 04-19-2012 |
20120277696 | DELIVERING AND/OR RECEIVING FLUIDS - The present invention generally relates to receiving bodily fluid through a device opening. In one aspect, the device includes a flow activator arranged to cause fluid to be released from a subject. A deployment actuator may actuate the flow activator in a deployment direction, which may in turn cause fluid release from a subject. The flow activator may also be moved in a retraction direction by a retraction actuator. In one aspect, the device may include a vacuum source that may help facilitate fluid flow into the opening of the device and/or may help facilitate fluid flow from the opening to a storage chamber. In one aspect, a device actuator may enable fluid communication between the opening and the vacuum source and the flow activator may be actuated after the enablement of fluid communication. | 11-01-2012 |
20130008442 | DELIVERY DEVICE AND RELATED METHODS - A dose delivery device with a mouthpiece having an inlet, an outlet, and an air path extending between the inlet and the outlet. A dose chamber having an opening may hold a dose, e.g., for inhalation by a user. One or more bypass inlets, two or more dispersion chambers, and/or flow arrangements in which incoming and outgoing flow in a dispersion chamber are transverse may be used to disperse a dose for delivery to a user. | 01-10-2013 |
20130032144 | DOSE DELIVERY DEVICE FOR INHALATION - Methods and devices for delivering a dose, such as a medicament, for inhalation. A dose may be stored by a delivery device and dispersed and delivered in a metered fashion to a subject, such as by the subject inhaling via a mouthpiece of the delivery device. One or more chambers of the device may have a toroidal shape and may be arranged to be selectively opened for fluid communication with a flow path of the delivery device, such as by sliding the chamber relative to a portion of the flow path. The flow path may include a restriction that permits air to bypass the chamber, and/or the chamber may be arranged so that fluid entering the chamber interacts with fluid exiting the chamber so as to enhance dispersion of the dose. | 02-07-2013 |
20130061851 | DELIVERY DEVICE AND RELATED METHODS - A dose delivery device with a mouthpiece having an inlet, an outlet, and an air path extending between the inlet and the outlet. A dose chamber having an opening may hold a dose, e.g., for inhalation by a user. A disc element may be arranged to move between a closed position in which the disc element closes the opening of the dose chamber, and an open position in which the disc opens the dose chamber to permit introduction of the dose into the air path of the device. Movement of the disc element from the closed position to the open position may be in a direction away from the dose chamber (e.g., a puller may engage the disc element and pull the element away from the chamber) and may leave a substantial portion of the dose in the dose chamber. | 03-14-2013 |
20130079666 | DELIVERING AND/OR RECEIVING FLUIDS - The present invention generally relates to receiving bodily fluid through a device opening. In one aspect, the device includes a flow activator arranged to cause fluid to be released from a subject. A deployment actuator may actuate the flow activator in a deployment direction, which may in turn cause fluid release from a subject. The flow activator may also be moved in a retraction direction by a retraction actuator. In one aspect, the device may include a vacuum source that may help facilitate fluid flow into the opening of the device and/or may help facilitate fluid flow from the opening to a storage chamber. In one aspect, a device actuator may enable fluid communication between the opening and the vacuum source and the flow activator may be actuated after the enablement of fluid communication. | 03-28-2013 |
20130112200 | SEALED CAPSULE INCLUDING AN INTEGRATED PUNCTURING MECHANISM - A sealed self-piercing capsule for storing and delivering a substance, such as a medicine, comprises one or more barrier layers forming a sealed chamber for containing the substance. An internal puncturing mechanism is disposed within the capsule chamber for puncturing a barrier layer to release the substance from the chamber. The internal puncturing mechanism may comprise a sharpened edge located on a movable tube, which moves relative to a barrier layer forming the sealed chamber to puncture the barrier layer. | 05-09-2013 |
20130138058 | DELIVERING AND/OR RECEIVING FLUIDS - The present invention generally relates to receiving bodily fluid through a device opening. In one aspect, the device includes a flow activator arranged to cause fluid to be released from a subject. A deployment actuator may actuate the flow activator in a deployment direction, which may in turn cause fluid release from a subject. The flow activator may also be moved in a retraction direction by a retraction actuator. In one aspect, the device may include a vacuum source that may help facilitate fluid flow into the opening of the device and/or may help facilitate fluid flow from the opening to a storage chamber. In one aspect, a device actuator may enable fluid communication between the opening and the vacuum source and the flow activator may be actuated after the enablement of fluid communication. | 05-30-2013 |
20130291865 | DELIVERY DEVICE AND RELATED METHODS - A dose delivery device includes a mouthpiece having an inlet and an outlet, a dose to be delivered to a subject via the mouthpiece and a housing surrounding the mouthpiece and the dose. The mouthpiece or other portion of the device may be moveable to form an opening in the housing, open a dose chamber and/or to extend the mouthpiece from the housing for delivery of the dose. The mouthpiece and housing may be arranged so that the mouthpiece remains attached to the housing after the opening is formed and the mouthpiece is extended from the housing. The housing may include a layer of barrier material that interacts with the mouthpiece to form the opening, e.g., the mouthpiece and barrier material may be moved relative to each other so that the barrier material is pierced. A dose chamber may be formed by a portion of the housing, a portion of the mouthpiece, and/or by any other suitable component of the delivery device. The dose chamber may be enclosed by the housing, and the dose chamber may be open to other spaces in the housing, or may be closed relative to other spaces enclosed by the housing. | 11-07-2013 |
20130327327 | AEROSOL DISPENSER WITH REPLACEABLE CARTRIDGE - Aerosolizing delivery apparatuses can include cartridges configured to be detachably connected to a delivery device. The cartridges can include: a housing defining a reservoir and a cartridge outlet, the cartridge outlet configured to permit fluid communication between the reservoir and an exterior of the cartridge. A surface of the housing can be configured to define a bypass port between the housing and a surface of the delivery device when the cartridge is assembled with the delivery device. | 12-12-2013 |
20140034053 | DELIVERY DEVICE AND RELATED METHODS - A delivery device that includes a cutter for opening a barrier layer to provide fluid access to a dose chamber, and a diverting structure for direct air flow toward the dose chamber. | 02-06-2014 |
20140102451 | DOSE DELIVERY DEVICE FOR INHALATION - Methods and devices for delivering a dose, such as a medicament, for inhalation. A dose may be stored by a delivery device and dispersed and delivered in a metered fashion to a subject, such as by the subject inhaling via a mouthpiece of the delivery device. One or more chambers of the device may have a toroidal shape and may be arranged to be selectively opened for fluid communication with a flow path of the delivery device, such as by sliding the chamber relative to a portion of the flow path. The flow path may include a restriction that permits air to bypass the chamber, and/or the chamber may be arranged so that fluid entering the chamber interacts with fluid exiting the chamber so as to enhance dispersion of the dose. | 04-17-2014 |
20140148746 | Limb Protection Device - A joint-supporting device comprises tensile members extending from a proximal cuff secured to the limb above the joint to a distal cuff secured to the limb below the joint, supplementing the tensile characteristics of the joint's tendons, ligaments, and other structure. The device may also comprise structure for limiting the range of motion and angular velocity of the joint. | 05-29-2014 |
20140216454 | DOSE DELIVERY DEVICE FOR INHALATION - Methods and devices for delivering a dose, such as a medicament, for inhalation. A dose may be stored by a delivery device and dispersed and delivered in a metered fashion to a subject, such as by the subject inhaling via a mouthpiece of the delivery device. One or more chambers of the device may have a toroidal shape and may be arranged to be selectively opened for fluid communication with a flow path of the delivery device, such as by sliding the chamber relative to a portion of the flow path. The flow path may include a restriction that permits air to bypass the chamber, and/or the chamber may be arranged so that fluid entering the chamber interacts with fluid exiting the chamber so as to enhance dispersion of the dose. | 08-07-2014 |
20140216457 | INHALATION DEVICE - The present invention provides for the integration of drug dispersion methods into a drug or medicine delivery system. The drug dispersion methods used include shear (e.g., air across a drug, with or without a gas assist), capillary flow or a venturi effect, mechanical means such as spinning, vibration, or impaction, and turbulence (e.g., using mesh screens, or restrictions in the air path). These methods of drug dispersion allow for all of the drug in the system to be released, allowing control of the dosage size. These methods also provide for drug metering, fluidization, entrainment, deaggragation and deagglomeration. The present invention also provides for the integration of a drug sealing system into the device. The drug sealing system provides a way of blocking the migration of drug from one area of the package to another. The drug seal system can also provide a method of tightly containing the drug until the package is opened, of directing airflow through the package and of managing and containing the drug during the package/device manufacturing process. | 08-07-2014 |
20150013053 | METHODS AND SYSTEMS FOR REDUCING SPREAD OF MICROBES - Methods and apparatuses of the invention relate to reduction of a spread of microbes, in particular from a toilet into the environment. In one aspect, a method of reducing a spread of microbes is provided comprising: providing a pressurized water supply to a toilet bowl; providing an externally accessible reservoir containing an anti-microbial additive; providing a conduit comprising a first end in fluid communication with the pressurized water supply and a second end in fluid communication with the externally accessible reservoir; and administering the anti-microbial additive into the toilet bowl, through the conduit; wherein the spread of microbes into an environment proximal to the toilet is reduced. In another aspect, a method of introducing an additive into a toilet is provided comprising: providing a pressurized water supply to a toilet bowl; providing an externally accessible reservoir containing an anti-microbial additive; providing a conduit comprising a first end in fluid communication with the pressurized water supply and a second end in fluid communication with the externally accessible reservoir; and administering the anti-microbial additive to the water at the level of the water supply when the toilet is flushed, wherein microbes are killed prior to the flush. Other aspects comprise apparatuses for reducing a spread of microbes and introducing an additive into a toilet. | 01-15-2015 |
20150038876 | DELIVERING AND/OR RECEIVING FLUIDS - The present invention generally relates to receiving bodily fluid through a device opening. In one aspect, the device includes a flow activator arranged to cause fluid to be released from a subject. A deployment actuator may actuate the flow activator in a deployment direction, which may in turn cause fluid release from a subject. The flow activator may also be moved in a retraction direction by a retraction actuator. In one aspect, the device may include a vacuum source that may help facilitate fluid flow into the opening of the device and/or may help facilitate fluid flow from the opening to a storage chamber. In one aspect, a device actuator may enable fluid communication between the opening and the vacuum source and the flow activator may be actuated after the enablement of fluid communication. | 02-05-2015 |
Patent application number | Description | Published |
20090202443 | METHODS OF IMPROVING SKIN QUALITY - Methods of improving skin quality are disclosed. Generally, the methods include topically administering an IRM compound to a treatment area of skin for a period of time and in an amount effective for improving the quality of the skin. Suitable IRM compound compounds include agonists of one or more TLRs. | 08-13-2009 |
20090246174 | TREATMENT FOR CUTANEOUS T CELL LYMPHOMA - The present invention provides method for treating a patient with cutaneous T cell lymphoma (CTCL). Generally, the methods include administering to the patient an IRM compound in an amount effective to ameliorate at least one symptom or clinical sign of CTCL. In some embodiments, the methods also include administering to the patient a priming dose of a Type I interferon. In another aspect, the invention provides methods of increasing a cell-mediated immune response of a cell population that includes cells affected by cutaneous T cell lymphoma. Generally, the methods include contacting the cell population with an IRM compound in an amount effective to increase at least one cell-mediated immune activity of the cell population. In some embodiments, the methods include contacting the cell population with a priming dose of a Type I interferon. | 10-01-2009 |
20100180902 | METHODS FOR DIAGNOSING SKIN LESIONS - Methods for diagnosing skin lesions are disclosed. Generally, the method include topically administering an IRM compound to a treatment area for a period of time and in an amount effective to cause a visible change in the appearance of a skin lesion including, in some cases, causing subclinical lesions to become visible. Suitable IRM compounds include agonists of one or more TLRs. | 07-22-2010 |
20110275662 | METHODS OF IMPROVING SKIN QUALITY - Methods of improving skin quality are disclosed. Generally, the methods include topically administering an IRM compound to a treatment area of skin for a period of time and in an amount effective for improving the quality of the skin. Suitable IRM compound compounds include agonists of one or more TLRs. | 11-10-2011 |
20130149341 | METHODS OF IMPROVING SKIN QUALITY - Methods of improving skin quality are disclosed. Generally, the methods include topically administering an IRM compound to a treatment area of skin for a period of time and in an amount effective for improving the quality of the skin. Suitable IRM compound compounds include agonists of one or more TLRs. | 06-13-2013 |
20150044279 | METHODS AND COMPOSITIONS FOR ENHANCING IMMUNE RESPONSE - Methods and compositions for enhancing the immune response to an IRM compound by depositing within a localized tissue region an IRM depot preparation that provides an extended residence time of active IRM within the localized tissue region. | 02-12-2015 |