Patent application number | Description | Published |
20090012068 | Condensed Imidazole Derivatives as Aldosterone Synthase Inhibitors - The application relates to novel heterocyclic compounds of the general formula (I) and salts, preferably pharmaceutically acceptable salts, thereof, in which R, R | 01-08-2009 |
20090029981 | SUBSTITUTED 4-PHENYLPIPERIDINES - The application relates to substituted 4-phenylpiperidines of the general formula and their salts, preferably their pharmaceutically acceptable salts, in which R | 01-29-2009 |
20090048241 | Condensed Imidazole Derivatives as Aromatase Inhibitors - The application relates to novel heterocyclic compounds of the general formula (I) and salts, preferably pharmaceutically acceptable salts, thereof, in which R, R | 02-19-2009 |
20090088426 | Substituted 4-Phenyl Piperidines for Use as Renin Inhibitors - Compounds of the general formula (I) and the salts thereof, preferably the pharmaceutically acceptable salts thereof; in which R | 04-02-2009 |
20090088576 | Process for the Stereoselective Preparation of Alcohols From Alpha, Beta-Insaturated Compounds - A process for the synthesis of an alcohol of formula (I), using as intermediate a compound of formula (V). | 04-02-2009 |
20090105503 | Process for Preparing organic compounds - Process for preparing a compound of the formula (I) in which R | 04-23-2009 |
20090118512 | Process for Preparing 6,7-Dihydro-5H-Imidazo[1,5-A]Pyridin-8-One - 6,7-Dihydro-5H-imidazo[1,5-a]pyridin-8-one (I), is obtainable in high yields by: 1) a process which proceeds from a suitably protected C-(3-hydroxypyridin-2-yl)methylamine whose amine is converted to the formamide which is then cyclized to the imidazo[1,5-a]pyridine and hydrogenated to the 6,7-dihydro-5H-imidazo[1,5-a]pyridin-8-one, and suitably protected C-(3-hydroxypyridin-2-yl)methylamines can be prepared either in 2 steps proceeding from commercially available 3-hydroxy-2-cyanopyridine [932-35-4] or in 3 steps proceeding from commercially available 2-hydroxymethylpyridin-3-ol [14173-30-9]; 2) a process for preparing 4-hydroxy-1-(1H-imidazol-4-yl)butan-1-one, an intermediate from the synthesis of 6,7-dihydro-5H-imidazo[1,5-a]pyridin-8-one (formula I), as described in WO 2002/040484, proceeding from N,N-dimethyl-2-(trialkylsilanyl)imidazole-1-sulphonamide by lithiation and subsequent reaction with a suitably protected 4-hydroxybutyraldehyde, followed by oxidation of the secondary alcohol, acid-induced deprotection of the imidazole and deprotection of the alcohol functionality; 3) a process which proceeds from 5,6,7,8-tetrahydroimidazo[1,5-a]pyridine [38666-30-7], which is oxidized. | 05-07-2009 |
20090192144 | Imidazo Compounds - The application relates to novel heterocyclic compounds of the general formula (I) and salts, preferably pharmaceutically acceptable salts, thereof in which R, R | 07-30-2009 |
20090192145 | Spiro-Imidazo Compounds - Novel heterocyclic compounds of the general formula (I) and salts, preferably pharmaceutically acceptable salts, thereof, in which R, R | 07-30-2009 |
20090192149 | Imidazo Compounds - The application relates to novel heterocyclic compounds of the general formula (I) and salts, preferably pharmaceutically acceptable salts, thereof, in which R, R | 07-30-2009 |
20090197909 | Bis-Heterocyclic Imidazolyl Compounds - The patent application relates to new heterocyclic compounds of the general formula (I) in which R, R | 08-06-2009 |
20090275651 | Alcanoic Acid Amides Substituted by Saturated O-Heterocycles - Compounds of the general formula (formula I) in which the meanings of the substituents R1 to R6 are as indicated in claim | 11-05-2009 |
20090306062 | 2,5-Disubstituted Piperidines - The application relates to 2,5-disubstituted piperidines, their preparation and use as medicines, especially as renin inhibitors, of the general formula (I) in which R, R | 12-10-2009 |
20100305110 | CONDENSED IMIDAZOLE DERIVATIVES AS ALDOSTERONE SYNTHASE INHIBITORS - The application relates to novel heterocyclic compounds of the general formula (I) and salts, preferable pharmaceutically acceptable salts, thereof, in which R, R | 12-02-2010 |
20110028512 | BIS-HETEROCYCLIC IMIDAZOLYL COMPOUNDS - Heterocyclic compounds of the general formula (I) are provided in which R, R | 02-03-2011 |
20110092492 | IMIDAZO COMPOUNDS - Heterocyclic compounds of the formula (I) and salts, preferably pharmaceutically acceptable salts thereof, are provided in which R, R | 04-21-2011 |
20110144197 | ALCANOIC ACID AMIDES SUBSTITUTED BY SATURATED O-HETEROCYCLES - Compounds of the general formula (formula I) | 06-16-2011 |