Maria Pia
Maria Pia Abbracchio, Milano IT
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20090156521 | Gpr17 modulators,method of screening and uses thereof - The invention provides GPR17 modulators, methods of screening and use thereof for diagnosis and therapy of diseases or dysfunctions involving GPR17 activation, particularly ischemic brain damage. | 06-18-2009 |
20150141410 | GPR17 Receptor Modulators - Chemical compounds are provided which act on GPR17 receptors and are useful in the treatment or amelioration of chronic and/or acute neurodegenerative diseases, such as multiple sclerosis, inflammatory diseases, pathologies involving the immune system, cardiovascular diseases, and renal diseases. | 05-21-2015 |
Maria Pia Arolfo, Pleasanton, CA US
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20080207610 | ALDH-2 INHIBITORS IN THE TREATMENT OF ADDICTION - Disclosed are novel isoflavone derivatives having the structure of Formula I | 08-28-2008 |
20090209533 | ALDH-2 INHIBITORS IN THE TREATMENT OF ADDICTION - Disclosed are novel isoflavone derivatives having the structure of Formula I | 08-20-2009 |
Maria Pia Catalani, Verona IT
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20150018345 | NOVEL NEUROKININ 1 RECEPTOR ANTAGONIST COMPOUNDS - The present invention relates to a compound according to formula (A) wherein n is 1 or 2; R1 and R2 are independently hydrogen, C | 01-15-2015 |
Maria Pia Cosma, Salerno IT
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20100311170 | METHOD FOR REPROGRAMMING DIFFERENTIATED CELLS - The present invention discloses a method for reprogramming a differentiated cell to an undifferentiated stem cell comprising fusing a pluripotent cell with a differentiated cell to form a fused cell, wherein the pluripotent cell is pre-treated or the fused cell is treated with a suitable amount of a Wnt/β-catenin pathway activator. | 12-09-2010 |
Maria Pia Rastaldi, Rho (mi) IT
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20150368608 | METHOD FOR THE THREE-DIMENSIONAL CO-CULTURE OF PODOCYTES AND ENDOTHELIAL CELLS AND RELATIVE IN VITRO CO-CULTURE SYSTEM - The present invention relates to a new three-dimensional co-culture method of podocytes and endothelial cells, and a relative co-culture system. Furthermore, the invention relates to the use of said co-culture system as an in vitro study model of pathologies affecting the kidneys, and in particular the renal glomerular filtration barrier. | 12-24-2015 |
Maria Pia Rastaldi, Rho IT
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20080214458 | SYNAPSE-SPECIFIC PROTEINS IN GLOMERULI - The present invention identifies that glomeruli express many neuron-specific and especially synapse-specific protein similarities. In particular, the present invention identifies Rab3A expression, including the expression of altered forms, as well as expression of other synapse-specific proteins including neurotransmitter receptors. The invention further identifies that modulation of the activity of these synapse-specific proteins results in modulation of podocytes. | 09-04-2008 |
Maria Pia Rastaldi, Rho (milano) IT
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20130177929 | METHOD FOR THE THREE-DIMENSIONAL CO- CULTURE OF PODOCYTES AND ENDOTHELIAL CELLS AND RELATIVE IN VITRO CO- CULTURE SYSTEM - The present invention relates to a new three-dimensional co-culture method of podocytes and endothelial cells, and a relative co-culture system. Furthermore, the invention relates to the use of said co-culture system as an in vitro study model of pathologies affecting the kidneys, and in particular the renal glomerular filtration barrier. | 07-11-2013 |
Maria Pia Zappavigna, Magenta IT
Patent application number | Description | Published |
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20090209506 | AMINO DERIVATIVES OF BETA-HOMOANDROSTANES AND BETA-HETEROANDROSTANES - New aminoalkoxyimino derivatives at position 3 of substituted B-homoandrostanes and B-heteroandrostanes, processes for their preparation, and to pharmaceutical compositions containing them for the treatment of cardiovascular disorders, such as heart failure and hypertension. In particular compounds having the general formula (I) are described, where the radicals have the meanings described in detail in the application. | 08-20-2009 |
20110053902 | AMINO DERIVATIVES OF ANDROSTANES AND ANDROSTENES AS MEDICAMENTS FOR CARDIOVASCULAR DISORDERS - Compounds of formula (I) wherein: the groups are as defined in the description, are useful for the preparation of medicaments for the treatment of cardiovascular disorders, in particular heart failure and hypertension. The compounds are inhibitors of the enzymatic activity of the Na | 03-03-2011 |