Giorgia
Giorgia De Franceschi, Scorze IT
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20150309045 | METHOD AND TOOLS FOR THE DETERMINATION OF CONFORMATION AND CONFORMATIONAL CHANGES OF PROTEINS AND OF DERIVATIVES THEREOF - A Method for the detection of the conformational state of a protein contained in a complex mixture of further proteins and/or other biomolecules, is proposed as well as assays for such a method. The method comprises the following steps: (1) Limited proteolysis of the complex mixture under a condition where the protein is in the conformational state to be detected leading to a first fragment sample; (2) Denaturation of the first fragment sample to a denaturated first fragment sample; (3) Complete fragmentation of the denaturated first fragment sample in a digestion step to a completely fragmented sample; and (4) Analytical analysis of the completely fragmented sample for the determination of fragments characteristic of having been the result both the limited proteolysis of step 1 as well as of the complete fragmentation in the digestion step 3. for the determination of the conformational state. | 10-29-2015 |
Giorgia Deplano, Casalpusterlengo IT
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20100125962 | TOOTHBRUSH WITH METAL SKELETON AND PLASTIC BODY MOULDED AROUND IT - Toothbrush having a head, a neck and a handle, the toothbrush comprising a plastic body and a metal skeleton, the plastic body being moulded around the metal skeleton, the metal skeleton extending from the handle through the neck and into the head of the toothbrush. | 05-27-2010 |
Giorgia Egidy, Paris FR
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20090098535 | UPREGULATION OF RACK-1 IN MELANOMA AND ITS USE AS A MARKER - The present invention concerns a method for diagnosing a melanoma in a mammal comprising the detection of the overexpression of RACK-1 protein in a melanocytic cell of said mammal, and the deduction of the presence of a melanoma from the overexpression of RACK-1 protein. The invention is also directed to a method for determining the tumoral status of a melanocytic cell of a mammal, comprising the detection of overexpression of RACK-1 protein in the melanocytic cell, and the deduction of the tumoral state of said cell from the overexpression of RACK-1 protein. | 04-16-2009 |
20100297632 | UPREGULATION OF RACK-1 IN MELANOMA AND ITS USE AS A MARKER - The present invention concerns a method for diagnosing a melanoma in a mammal comprising the detection of the overexpression of RACK-1 protein in a melanocyte cell of said mammal, and the deduction of the presence of a melanoma from the overexpression of RACK-1 protein. The invention is also directed to a method for determining the tumoral status of a melanocyte cell of a mammal, comprising the detection of overexpression of RACK-1 protein in the melanocyte cell, and the deduction of the tumoral state of said cell from the overexpression of RACK-1 protein. | 11-25-2010 |
20110045475 | UPREGULATION OF RACK-1 IN MELANOMA AND ITS USE AS A MARKER - The present invention concerns a method for diagnosing a melanoma in a mammal comprising the detection of the overexpression of RACK-1 protein in a melanocytic cell of said mammal, and the deduction of the presence of a melanoma from the overexpression of RACK-1 protein. The invention is also directed to a method for determining the tumoral status of a melanocytic cell of a mammal, comprising the detection of overexpression of RACK-1 protein in the melanocytic cell, and the deduction of the tumoral state of said cell from the overexpression of RACK-1 protein. | 02-24-2011 |
20130273532 | UPREGULATION OF RACK-1 IN MELANOMA AND ITS USE AS A MARKER - The present invention concerns a method for diagnosing a melanoma in a mammal comprising the detection of the overexpression of RACK-1 protein in a melanocyte cell of said mammal, and the deduction of the presence of a melanoma from the overexpression of RACK-1 protein. The invention is also directed to a method for determining the tumoral status of a melanocyte cell of a mammal, comprising the detection of overexpression of RACK-1 protein in the melanocyte cell, and the deduction of the tumoral state of said cell from the overexpression of RACK-1 protein. | 10-17-2013 |
Giorgia Franchin, Cambridge, MA US
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20150307385 | Methods and apparatus for additive manufacturing of glass - In illustrative implementations of this invention, a crucible kiln heats glass such that the glass becomes or remains molten. A nozzle extrudes the molten glass while one or more actuators actuate movements of the nozzle, a build platform or both. A computer controls these movements such that the extruded molten glass is selectively deposited to form a 3D glass object. The selective deposition of molten glass occurs inside an annealing kiln. The annealing kiln anneals the glass after it is extruded. In some cases, the actuators actuate the crucible kiln and nozzle to move in horizontal x, y directions and actuate the build platform to move in a z-direction. In some cases, fluid flows through a cavity or tubes adjacent to the nozzle tip, in order to cool the nozzle tip and thereby reduce the amount of glass that sticks to the nozzle tip. | 10-29-2015 |
Giorgia Iarussi, Rome IT
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20110154358 | METHOD AND SYSTEM TO AUTOMATICALLY OPTIMIZE EXECUTION OF JOBS WHEN DISPATCHING THEM OVER A NETWORK OF COMPUTERS - A computer implemented method, system, and/or computer program product selects a target computer to execute a job. For each computer in a system, a statistical mean of last job duration values is computed from historical records for all computers that have executed the job. Multiple pools of computers are selected based on a statistical mean of last job duration values. A ratio for each pool from the multiple pools is computed. This ratio is a ratio of the quantity of current executions of the job in a particular pool compared to a total of current job executions of the job in all of the multiple pools of computers. A particular pool of computers, which has a computed ratio that is closest to a preselected ratio, is selected. A target computer is selected from the particular pool of computers to execute a next iteration of the job. | 06-23-2011 |
Giorgia Pastorin, Singapore SG
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20120089117 | APPARATUS THAT INCLUDES NANO-SIZED PROJECTIONS AND A METHOD FOR MANUFACTURE THEREOF - An apparatus that includes a nano-projection array and an application unit configured to displace the nano-projection array to thereby deliver a composition (e.g., vaccine) to a controlled depth within the skin. The nano-projection array includes nano-projections carried by a carrier substrate. The application unit includes a peripheral structure and a displaceable carrier. The nano-projection array can be disposed within the peripheral structure. Displacement of the displaceable carrier causes a corresponding displacement to the nano-projection array. The displacement of the displaceable carrier can be controlled. For instance the distance of displacement of the displaceable carrier can be controlled. A method or process for manufacturing the apparatus is also provided. | 04-12-2012 |
20130095083 | Method For Controlling And Accelerating Differentiation Of Stem Cells Using Graphene Substrates - The invention relates to methods for directing differentiation of stem cells comprising graphene. In additional embodiments, the invention relates to methods for repairing and improving bone tissue functions comprising accelerating differentiation in stem cell growth by exposing stem cells to graphene and transplanting the graphene with the exposed stem cells in the tissue at the site of repair. | 04-18-2013 |
Giorgia Salvagiotto, Madison, WI US
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20100216181 | METHODS AND COMPOSITIONS FOR THE DIFFERENTIATION OF STEM CELLS - The present invention provides methods and compositions for the production of hematopoietic progenitor cells or endothelial progenitor cells from human pluripotent stem cells using a defined cell culture medium without the need to utilize feeder cells or serum. In some embodiments, differentiation is accomplished using hypoxic atmospheric conditions. The defined medium of the present invention may contain growth factors and a matrix component. The hematopoietic progenitor cells may be further differentiated into cell lineages including red blood cells, macrophages, granulocytes, and megakaryocytes. The endothelial progenitor cells may be further differentiated into endothelial cells. Also disclosed are screening assays for identification of candidate substances that affect differentiation of pluripotent stem cells into progenitor cells. | 08-26-2010 |
Giorgia Sgalari, Bologna IT
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20140014251 | PROCESS AND APPARATUS FOR MANUFACTURING TYRES FOR VEHICLE WHEELS - A carcass ply is built on a forming drum by application of a plurality of strip-like elements, through the steps of: setting a width of these strip-like elements, setting a width of the overlapped part between two adjacent strip-like elements, setting a fitting diameter of the forming drum, calculating a whole number of strip-like elements to be applied. The whole number of strip-like elements is applied by rotating the forming drum around a geometric rotation axis thereof, and applying pairs of strip-like elements by means of a first and second laying unit located close to opposite portions of the forming drum. When the calculated whole number of strip-like elements is an odd number, the first laying unit is shifted along an adjustment path orthogonal to the geometric rotation axis and substantially tangent to the radially external laying surface of the forming drum. | 01-16-2014 |
Giorgia Sgalari, Milano IT
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20090009310 | Wheel Having a Controlled Pressure and a Pressure Reservoir - A wheel having a controlled pressure includes a rim associated with a tank adapted to be filled with a fluid to a first pressure; a tyre mounted on the rim and having an inner volume inflated to an operating pressure at a reference temperature, the operating pressure being lower than the first pressure; and at least one valve assembly adapted to establish a communication between the tank, the inner volume of the tyre and the external environment. The valve assembly includes a command valve, an exhaust valve and a compensation valve operatively associated with each other. The command valve controls communication between the tank and the inner volume of the tyre. The exhaust valve is connected to the external environment, to the inner volume, to the command valve and to the compensation valve. The compensation valve is connected to the exhaust valve and the command valve. The command valve includes an inner chamber connected with the exhaust valve and the compensation valve in such a manner that the command valve is operated by the exhaust valve and the compensation valve through a pressure variation of the inner chamber in response to a variation of the inner pressure of the tyre. | 01-08-2009 |
20100024949 | PROCESS FOR MANUFACTURING TYRES BY APPLICATION OF STRIPS HAVING DIFFERENT WIDTHS - A process for manufacturing a tyre includes: providing a first plurality of strip-like elements, each substantially having a first effective width; providing at least a second plurality of strip-like elements, each substantially having a second effective width; arranging the strip-like elements of the first plurality and of the second plurality on a support by approaching side edge portions thereof to one another, so as to form at least one reinforcing component of the tyre on the support; wherein the first effective width is different from the second effective width. | 02-04-2010 |
20100300603 | PROCESS AND APPARATUS FOR MANUFACTURING TYRES FOR VEHICLE WHEELS - A carcass ply is built on a forming drum by application of a plurality of strip-like elements by the steps of: setting a width of these strip-like elements, setting a width of the overlapped part between two adjacent strip-like elements, setting a fitting diameter of the forming drum by calculating a corresponding extension of a radially external laying surface, and calculating a whole number of strip-like elements to be applied. The whole number of strip-like elements is applied by rotating the forming drum around a geometric rotation axis thereof, and applying pairs of strip-like elements by means of a first laying unit and a second laying unit located close to opposite portions of the forming drum relative to the geometric rotation axis. When the calculated whole number of strip-like elements is an odd number, before at least one application step, the first laying unit is shifted along an adjustment path orthogonal to the geometric rotation axis and substantially tangent to the radially external laying surface of the forming drum. | 12-02-2010 |
Giorgia Tordini, Eindhoven NL
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20100271843 | ILLUMINATION SYSTEM, LUMINAIRE AND BACKLIGHTING UNIT - The invention relates to an illumination system ( | 10-28-2010 |
20110026246 | LED BASED LIGHT SOURCE - There is provided a light-emitting device ( | 02-03-2011 |
20110026257 | WHITE LIGHT-EMITTING DEVICE - A light-emitting device comprises a light source adapted to emit light of a first wavelength range; a reflective body comprising a reflective layer; a wavelength converting layer comprising a wavelength converting material adapted to absorb light of said first wavelength range and to emit light of a second wavelength range, said wavelength converting layer and said light source being arranged mutually spaced apart; and light-scattering elements adapted to scatter light of at least said first wavelength range; wherein at least part of said light-scattering elements are arranged in the path of light from said light source to said wavelength converting layer. The light-emitting device according to the invention provides improved uniformity in colour and also improved brightness uniformity. | 02-03-2011 |
Giorgia Tordini, Winterswijk NL
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20110164398 | LUMINAIRE AND ILLUMINATION SYSTEM - The invention relates to a luminaire ( | 07-07-2011 |
Giorgia Tordini, Lyon FR
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20110170278 | ILLUMINATION SYSTEM, LUMINAIRE AND DISPLAY DEVICE - The invention relates to an illumination system ( | 07-14-2011 |
20120147621 | LIGHTING DEVICE HAVING A LENS INCLUDING A PLURALITY OF INTERCONNECTED ELONGATED LIGHT-GUIDING ELEMENTS - A lighting device ( | 06-14-2012 |
20120163027 | LIGHT-EMITTING DEVICE - It is disclosed a light-emitting device ( | 06-28-2012 |
20120176813 | LIGHT EMITTING DEVICE COMPRISING A LIGHT GUIDE PLATE WITH REFLECTIVE SHIELDING WITH GLARE REDUCTION - The present invention relates to light emitting devices and more specifically to light emitting devices comprising light guides making use of total internal reflection (TIR). The light emitting device ( | 07-12-2012 |
20140036494 | Luminaire and illumination system - Disclosed is a luminaire having a light exit window ( | 02-06-2014 |
20140268641 | Illumination system, luminaire, collimator, and display device - The invention relates to an illumination system ( | 09-18-2014 |
Giorgia Valsesia, Giubiasco CH
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20100009405 | Biosynthetic process for the preparation of gallidermin - A process for the production of gallidermin comprises fermentative production of the respective biologically in-active and non-toxic pre-form(s) by either genetically engineered producer organism or mutants of the natural producer organism that are deficient for the extracelluar gallidermin pathway specific serine-pro tease. The process includes a downstream process in which a pre-form of gallidermin is isolated from the fermentation and bio-catalytically activated, followed by purification of the mature and active gallidermin. | 01-14-2010 |